WEBVTT - Selects: How the Flu Works

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<v Speaker 1>Ooh god, Hi everybody, it's Chuck here. Oh boy. My

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<v Speaker 1>selection this week is Hell the Flu Works, and I'll

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<v Speaker 1>give you one reason why. This is from November fourteenth,

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<v Speaker 1>twenty seventeen. H I hope you like it. I'm going

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<v Speaker 1>back to bed. Welcome to Stuff You Should Know, a

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<v Speaker 1>production of iHeartRadio.

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<v Speaker 2>Hey, and welcome to the podcast. I'm Josh Clark, There's

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<v Speaker 2>Charles W Chuck Bryant, there's Jerry. This is Stuff you

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<v Speaker 2>Should Know about the flu, which I have.

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<v Speaker 1>You know the flu?

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<v Speaker 2>Do you? I don't know, man, I can't. I can't.

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<v Speaker 2>I've been on the planet for forty one years. Okay,

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<v Speaker 2>I still can't really tell the difference between a flu

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<v Speaker 2>and a cold.

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<v Speaker 1>I think the difference that I can tell, and I

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<v Speaker 1>don't get a flu much. You know, always get the

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<v Speaker 1>stomach bug, which, as it turns out, is not a

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<v Speaker 1>flu I just learned. But I don't get the flu

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<v Speaker 1>flu much. But I can always tell though when I'm

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<v Speaker 1>super achy, like the flu just makes me feel like

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<v Speaker 1>dog doodoo. Right, Where's the cold? Is just a big inconvenience?

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<v Speaker 2>Yeah, I've had uh no, I've definitely had like lots

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<v Speaker 2>of aches and I woke up like shivering one night.

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<v Speaker 1>I don't see you. I had a fever, for sure,

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<v Speaker 1>I guess.

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<v Speaker 2>So, I guess it must have just been one night

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<v Speaker 2>in the middle of the night. So that's that's the flu, right, probably,

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<v Speaker 2>So I guess I do have the flu. No, no joke, everybody.

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<v Speaker 1>Well, I'm erecting the clear glass in between us.

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<v Speaker 2>Yeah. I think that I've had it long enough now

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<v Speaker 2>based on the research from this article that I'm not contagious,

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<v Speaker 2>or else I would have called this off.

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<v Speaker 1>So did you get it in New York?

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<v Speaker 2>I wonder, I think so. Yeah, I'm letty New York, right, Yeah,

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<v Speaker 2>Which I was like, I was just walking walking around

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<v Speaker 2>like with my hands inside of a couple of like

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<v Speaker 2>plastic Dwayne Reid bags and it still didn't work.

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<v Speaker 1>Well, that was your problem probably right there, Dwayne Reid.

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<v Speaker 2>Because I didn't take them off when I ate gross. Yeah. So, yes,

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<v Speaker 2>we were in New York for some Bellhouse shows, right,

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<v Speaker 2>those went pretty well?

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<v Speaker 1>Yeah, I thought they were great.

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<v Speaker 2>All right, So the flu. We won't reminisce about past victories.

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<v Speaker 2>We'll just talk about the flu instead.

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<v Speaker 1>Yeah, how about a stat right off the get go? Here?

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<v Speaker 2>Okay, the flu. And also sorry everybody for the sniffling

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<v Speaker 2>that we knew inevitably happen. I'm trying hard not to

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<v Speaker 2>do it.

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<v Speaker 1>You're a method podcaster, all right, which is also what

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<v Speaker 1>I said in my very first episode. That's right, remember that. Yep,

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<v Speaker 1>it's not any funnier now. So the CDC right here

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<v Speaker 1>in Atlanta Centers for Disease Control and Prevention, not the CDCP.

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<v Speaker 2>No, they just stuck with the original.

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<v Speaker 1>Yes, they reckon that. About five to twenty between five

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<v Speaker 1>percent and twenty percent of United States people's get the

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<v Speaker 1>flu each year, compared to about ten percent to twenty

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<v Speaker 1>five percent in dirty cold Canada.

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<v Speaker 2>Right, I know. And normally when you get the flu,

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<v Speaker 2>it's just you're laid up for a couple of days, right, Yeah,

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<v Speaker 2>like you said, you feel like dog do or something

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<v Speaker 2>like that. Yeah, that's the seasonal flu. But even with

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<v Speaker 2>the seasonal flu, which usually here in the United States

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<v Speaker 2>or in North America runs from what like October to March,

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<v Speaker 2>yeah roughly. Uh, and then I didn't really think about

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<v Speaker 2>this before, but in the Southern Hemisphere it runs the

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<v Speaker 2>opposite and actually peaks in August, right, Yeah, most of

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<v Speaker 2>the time, it's just an inconvenience for you, but it

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<v Speaker 2>actually kills people sometimes.

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<v Speaker 1>Yeah, it can be dangerous for sure.

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<v Speaker 2>So in two thy eleven and twelve that was a

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<v Speaker 2>pretty low year, and for deaths from the flu in

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<v Speaker 2>the US, there were twelve thousand people who died from

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<v Speaker 2>the flu or complications from the flu. Twenty twelve thirteen

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<v Speaker 2>flu season, fifty six thousand people died that year, and

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<v Speaker 2>I think the average is something around thirty six thousand

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<v Speaker 2>people in the US die from the flu every year.

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<v Speaker 1>Yeah, and apparently the World Health Organization says around the

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<v Speaker 1>world as many as a quarter of a million people

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<v Speaker 1>to a half a million people can die every year

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<v Speaker 1>from the flu.

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<v Speaker 2>Right, there's a lot of folks it is. So, I mean,

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<v Speaker 2>in the idea of dying from the flu, that's awful

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<v Speaker 2>because I mean, if you feel bad enough, as it

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<v Speaker 2>is from a flu that you recover from in a

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<v Speaker 2>few days, imagine dying from that. That would just be

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<v Speaker 2>a terrible way to die.

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<v Speaker 1>Yeah.

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<v Speaker 2>And the whole thing, chuck, comes down to this little

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<v Speaker 2>tiny virus, that influenza virus, and there's different types and

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<v Speaker 2>influenza I found actually a shout out to the Italian

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<v Speaker 2>name for it originally did you know this? Uh? Did not,

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<v Speaker 2>So I'm going to say it normally, but then you

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<v Speaker 2>have to say it in your famous Italian accent, Influenza

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<v Speaker 2>di fredo.

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<v Speaker 1>Are you talking about the influenza de fredo?

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<v Speaker 2>Yeah, well, which means influence of the cold. Oh, all right,

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<v Speaker 2>a lot of For many, many, many many years, because

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<v Speaker 2>the flu is most predominant in the colder months, everybody

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<v Speaker 2>just assumed that it was the actual cold that was

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<v Speaker 2>getting you sick, right, That turns out not to be true.

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<v Speaker 2>It's an actual it's a virus that does seem to

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<v Speaker 2>favor the cold, drier conditions of the winter months. But

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<v Speaker 2>this little tiny virus gets into your body and it

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<v Speaker 2>starts this chain reaction that is just fascinating.

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<v Speaker 1>Yeah, so it is a respiratory illness. So, like I

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<v Speaker 1>said before, when you hear people say the stomach flu,

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<v Speaker 1>which I've said lot in my life because I get

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<v Speaker 1>it once a year with the poopy butt and the

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<v Speaker 1>vomitous mouth and the ill belly.

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<v Speaker 2>At the same time. Though I can't I think I've

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<v Speaker 2>asked you this before, but.

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<v Speaker 1>As it literally ever happened at the same time, I

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<v Speaker 1>think once in my life.

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<v Speaker 2>Man, that's rough.

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<v Speaker 1>I was on the john with a bucket. That's so rough. Well,

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<v Speaker 1>the worst time I ever had it. I may have

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<v Speaker 1>told the story before. I was sick at a friend's house,

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<v Speaker 1>which is the worst when I was not living in Atlanta,

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<v Speaker 1>but I was in Atlanta, and I was like, I

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<v Speaker 1>just got to get to my mom's house. Well, yeah,

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<v Speaker 1>I was like, I just much more comfortably being sick there,

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<v Speaker 1>and he was working. It was just one of those things.

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<v Speaker 1>And so I got in my brother's car that I

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<v Speaker 1>was borrowing while I was in town.

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<v Speaker 2>I don't like where this story's going.

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<v Speaker 1>And I drove no lie, probably about one hundred miles

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<v Speaker 1>an hour to Snellville from Atlanta, thinking, and I pooped

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<v Speaker 1>in my pants in the car, and I remember thinking,

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<v Speaker 1>if a cop pulls me over, he would have to

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<v Speaker 1>be a cold heartless individual to give me a ticket,

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<v Speaker 1>because I would just say, sir, don't take me to prison,

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<v Speaker 1>take me to a hospital because I'm dying. Yeah, so

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<v Speaker 1>I trove one hundred miles an hour. It's kind of fun.

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<v Speaker 2>So you made it home. You showed up with poopy

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<v Speaker 2>pants and your mom took care of you.

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<v Speaker 1>Yep, showed up to Diane's house, and I lived. But anyway,

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<v Speaker 1>that was a long way of setting up this which

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<v Speaker 1>is that is actually not a flu. The stomach flu

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<v Speaker 1>is not because the flu is one hundred percent of

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<v Speaker 1>respiratory illness, right, and is not something that happens in

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<v Speaker 1>your stomach or in your butt. Right.

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<v Speaker 2>And let's let's talk first before we talk about the

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<v Speaker 2>actual effect of the flu. Let's talk about the virus

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<v Speaker 2>a little bit. I second, Okay, So back in nineteen

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<v Speaker 2>thirty one, there was this Iowa farm physician, which is

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<v Speaker 2>to say he was a human physician of humans, but

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<v Speaker 2>he probably lived on a farm because it was Iowa

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<v Speaker 2>in nineteen thirty one. Yeah, his name was Richard schop

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<v Speaker 2>and he was trying to figure out what this bug

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<v Speaker 2>that was getting people was. And he investigated with pigs first,

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<v Speaker 2>because there are plenty of other animals that can come

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<v Speaker 2>down with the flu, not just humans, right, right, And

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<v Speaker 2>he finally isolated, isolated a flu virus in swine and

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<v Speaker 2>it led to this discovery of the isolation of the

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<v Speaker 2>flu virus in humans too. So right after that they

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<v Speaker 2>started classifying the flu by strains.

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<v Speaker 1>You got A, B, and C, right, So A is

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<v Speaker 1>the most common and most severe that's the bad news. Yeah,

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<v Speaker 1>B is a little milder, a little less prevalent. And

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<v Speaker 1>then we go all the way down to C, which

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<v Speaker 1>is I get the feeling. CE doesn't happen a lot,

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<v Speaker 1>and it definitely isn't the one that you're going to

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<v Speaker 1>have like a big epidemic of the flu from a sea.

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<v Speaker 2>Yeah. I couldn't find much on C influenza either orse C. Yeah,

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<v Speaker 2>it'll make a comeback one day and it'll shock the

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<v Speaker 2>heck out of all of us. Right, So Type A

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<v Speaker 2>infects all sorts of different species, right, humans, birds of

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<v Speaker 2>all kinds, pigs, bats, horses, even.

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<v Speaker 1>Yeah, I mean remember the Avian flu that was that

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<v Speaker 1>scared the world, and that was a right, that was

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<v Speaker 1>a strain.

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<v Speaker 2>B strain is almost exclusively effective of humans. Apparently. The

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<v Speaker 2>only other species we've ever found a Type B influenza

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<v Speaker 2>virus in is seals. God knows where they got it from,

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<v Speaker 2>or if we got it from seals, who knows? Maybe

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<v Speaker 2>up North, I don't know. And then that C one,

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<v Speaker 2>it just infects humans and pigs. So you got the

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<v Speaker 2>three types. And then one other thing about them about

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<v Speaker 2>the classification of flu strains is that there are also subtypes, right,

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<v Speaker 2>And so you mentioned like avian flu and the one

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<v Speaker 2>that scared everybody. I think H five N one, Yeah,

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<v Speaker 2>that was it.

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<v Speaker 1>I remember.

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<v Speaker 2>So that H and the N are the they refer

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<v Speaker 2>to the two kinds of the two main proteins that

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<v Speaker 2>you find on the outside of a flu virus, hemagglutinin

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<v Speaker 2>and neurrominiase. Okay, and so depending on those types of

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<v Speaker 2>H protein or M protein. Uh, that's that's how they

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<v Speaker 2>subtype flu strains.

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<v Speaker 1>Yeah. So, I mean that's a good little factoid. I

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<v Speaker 1>don't think anyone really understands what those letters mean.

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<v Speaker 2>That's what they mean, you know.

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<v Speaker 1>Yeah, But as far as you're concerned, just pay attention

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<v Speaker 1>to the news, and when they talk about the scary ones,

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<v Speaker 1>they'll mention those letters in numbers, and then you can

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<v Speaker 1>impress your friends.

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<v Speaker 2>Yeah, you can be like, oh, well they're talking about

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<v Speaker 2>hema glutenant and neurominidase, and they'll.

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<v Speaker 1>Say, shut up, nerd, I hope you get sick. So,

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<v Speaker 1>as far as the standard flu that we're talking about here,

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<v Speaker 1>the virus, it gets into your body and it kind

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<v Speaker 1>of makes a b line to your respiratory tract and

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<v Speaker 1>it binds with your cells. It's viruses. Did we do

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<v Speaker 1>one a general on viruses?

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<v Speaker 2>The one I think we really went in depth on

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<v Speaker 2>was HIV, where we talked about how virus centers the

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<v Speaker 2>body takes over. It's just vicious, it is, but it's

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<v Speaker 2>also it's kind of like admirable in a really deadly

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<v Speaker 2>efficient way, you know.

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<v Speaker 1>It is. So they bind to the surface of the

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<v Speaker 1>cells in that respiratory tract and then they say, hey,

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<v Speaker 1>i'd like you to meet my little friend RNA. Why

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<v Speaker 1>don't Why don't I inject my genetic information into your

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<v Speaker 1>nucleus and see how you like it? Right?

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<v Speaker 2>And when it does that, the cell has been officially hijacked,

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<v Speaker 2>and the virus uses the cell's own RNA transcription process

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<v Speaker 2>to create the proteins that are needed to make new

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<v Speaker 2>versions of the virus. The virus is using this host

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<v Speaker 2>cell in your respiratory tract to make copies of itself,

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<v Speaker 2>and suddenly, before the cell knows what's going on, it's

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<v Speaker 2>made millions of copies of these viruses. Right, And apparently

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<v Speaker 2>when you talk about it step by step, it seems

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<v Speaker 2>like this takes a little while, right, No, in seconds.

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<v Speaker 2>Seconds after that, the virus has entered your respiratory cell.

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<v Speaker 2>Millions of copies of it have been made.

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<v Speaker 1>Yeah, Like this is happening so fast it moves in there,

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<v Speaker 1>it says I'm in charge.

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<v Speaker 2>Now, so out of the way.

0:12:36.840 --> 0:12:40.200
<v Speaker 1>Yeah, completely out of the way. I'm running the show. Here.

0:12:40.320 --> 0:12:43.560
<v Speaker 1>We're copying each other and we're going to move out

0:12:43.600 --> 0:12:45.480
<v Speaker 1>to the cell membrane because this cell's going to die

0:12:45.600 --> 0:12:47.880
<v Speaker 1>very quickly, and then that's just going to poof me

0:12:47.920 --> 0:12:51.000
<v Speaker 1>out into the body further to infect other cells. And

0:12:51.120 --> 0:12:53.600
<v Speaker 1>it's scary how quickly this happens.

0:12:53.760 --> 0:12:55.559
<v Speaker 2>Right, So if you think about it, if that first

0:12:55.559 --> 0:13:00.280
<v Speaker 2>cell produces millions of viruses, viral copies, and then they're

0:13:00.280 --> 0:13:03.040
<v Speaker 2>released from the cell out into the rest of the

0:13:03.400 --> 0:13:07.240
<v Speaker 2>other respiratory cells, and each of those infects another cell,

0:13:07.320 --> 0:13:09.800
<v Speaker 2>and then those cells all make millions. You see how

0:13:09.880 --> 0:13:16.520
<v Speaker 2>quickly these viruses reproduce in your body. Yeah, And once

0:13:16.559 --> 0:13:19.680
<v Speaker 2>that starts to happen, you are infectious. I think once

0:13:19.760 --> 0:13:24.200
<v Speaker 2>that first cell ruptures, you become infectious. But this can

0:13:24.240 --> 0:13:26.640
<v Speaker 2>be like a day before symptoms. Right, So this is

0:13:27.160 --> 0:13:30.120
<v Speaker 2>something people are always saying, like, oh, I'm not infectious anymore,

0:13:30.280 --> 0:13:33.720
<v Speaker 2>like me I said it earlier too, right, But supposedly

0:13:34.120 --> 0:13:37.520
<v Speaker 2>the day before you even know you're sick, the day

0:13:37.520 --> 0:13:40.600
<v Speaker 2>before the first symptoms start, before you start like sniffling

0:13:40.640 --> 0:13:43.800
<v Speaker 2>a little bit or whatever. Huh, you're infectious, buddy. Yeah,

0:13:43.840 --> 0:13:47.360
<v Speaker 2>And you're infectious up to seven days after that day

0:13:47.400 --> 0:13:49.520
<v Speaker 2>you first start showing symptoms with the flu. And if

0:13:49.520 --> 0:13:52.040
<v Speaker 2>you're a kid, you can be infectious even longer because

0:13:52.120 --> 0:13:55.400
<v Speaker 2>if kids are anything, they're walking germ factories.

0:13:55.679 --> 0:13:57.559
<v Speaker 1>They are just disgusting monsters.

0:13:57.800 --> 0:13:58.840
<v Speaker 2>It's hilarious.

0:14:00.280 --> 0:14:03.240
<v Speaker 1>It's true. Man, Like, my kid didn't get sick at

0:14:03.240 --> 0:14:06.280
<v Speaker 1>all for the first eighteen months of her life, and

0:14:06.320 --> 0:14:09.120
<v Speaker 1>I thought, I've got a wonder baby. Yeah, really, I

0:14:09.160 --> 0:14:11.959
<v Speaker 1>don't know what's going on. We put her in daycare

0:14:12.000 --> 0:14:13.800
<v Speaker 1>a couple of days a week, and she was sick

0:14:13.960 --> 0:14:15.480
<v Speaker 1>NonStop for the next six months.

0:14:15.520 --> 0:14:16.439
<v Speaker 2>Man. That is rough.

0:14:16.679 --> 0:14:18.360
<v Speaker 1>It is rough. And then they get the family sick,

0:14:18.480 --> 0:14:20.200
<v Speaker 1>and we'll talk a little bit about that and how

0:14:20.200 --> 0:14:24.480
<v Speaker 1>that happens. But all this is to say, during flu season,

0:14:24.640 --> 0:14:27.000
<v Speaker 1>especially if you work in like an office where you

0:14:27.040 --> 0:14:29.320
<v Speaker 1>know when you hear like the flu's going around or whatever,

0:14:29.840 --> 0:14:32.600
<v Speaker 1>or anywhere you work, or in school, if you hear

0:14:32.640 --> 0:14:36.320
<v Speaker 1>about the flu going around, even if you don't feel sick,

0:14:36.680 --> 0:14:40.760
<v Speaker 1>or your cube mate doesn't feel or look sick. Just

0:14:40.800 --> 0:14:42.200
<v Speaker 1>start washing your hands a lot.

0:14:42.640 --> 0:14:45.200
<v Speaker 2>Oh yeah, that's like they say, that's the best way

0:14:45.240 --> 0:14:47.640
<v Speaker 2>to prevent getting the flu or spreading the flu is

0:14:47.760 --> 0:14:49.000
<v Speaker 2>washing your hands a lot.

0:14:49.320 --> 0:14:49.600
<v Speaker 1>Do it.

0:14:49.600 --> 0:14:53.360
<v Speaker 2>And it's so simple that you almost might discount it,

0:14:53.440 --> 0:14:55.600
<v Speaker 2>but it's actually true, Like that's the best way to

0:14:55.640 --> 0:14:57.920
<v Speaker 2>do it. You can wash the flu virus off of

0:14:57.960 --> 0:15:01.360
<v Speaker 2>your hands with some soap that will buy and the

0:15:01.400 --> 0:15:02.800
<v Speaker 2>water will wash it right off.

0:15:03.280 --> 0:15:04.680
<v Speaker 1>Wash that flu right out of your hair.

0:15:05.040 --> 0:15:09.840
<v Speaker 2>Yeah, and if you have the flu, stay home. Yeah,

0:15:09.880 --> 0:15:12.320
<v Speaker 2>everybody but me stay home.

0:15:12.760 --> 0:15:14.800
<v Speaker 1>Well, we're up against it. We had to record a.

0:15:14.760 --> 0:15:19.600
<v Speaker 2>Today and also wash your hands just constantly. Like if

0:15:19.640 --> 0:15:22.120
<v Speaker 2>I'm about to touch anything, I'll wash my hands first.

0:15:22.640 --> 0:15:25.280
<v Speaker 2>If I'm going to go somewhere outside of the hot zone,

0:15:25.840 --> 0:15:28.960
<v Speaker 2>which is whatever room I'm sequestered in, you know, I

0:15:29.000 --> 0:15:30.120
<v Speaker 2>will wash my hands.

0:15:30.840 --> 0:15:32.720
<v Speaker 1>You know I appreciate that. I mean, trust me. We're

0:15:32.720 --> 0:15:34.440
<v Speaker 1>in this tiny studio now, the three of us.

0:15:34.600 --> 0:15:36.000
<v Speaker 2>I know, I'm trying not to breathe.

0:15:36.960 --> 0:15:39.240
<v Speaker 1>You know, you've done all this on one breath. It's impressive,

0:15:39.400 --> 0:15:42.840
<v Speaker 1>I know. Well, quickly before we take a break, so

0:15:42.880 --> 0:15:46.880
<v Speaker 1>you can breathe again. We're going to talk about symptoms afterward.

0:15:48.120 --> 0:15:51.400
<v Speaker 1>Before you get these symptoms, though, what's happening is your

0:15:51.400 --> 0:15:55.160
<v Speaker 1>respiratory system is going to become inflamed, and this inflammation

0:15:56.160 --> 0:15:59.360
<v Speaker 1>might stick around for a few weeks, but from there

0:16:00.040 --> 0:16:02.200
<v Speaker 1>it moves into your bloodstream, and then that's when you're

0:16:02.240 --> 0:16:04.560
<v Speaker 1>gonna get these symptoms once it sort of moves into

0:16:04.600 --> 0:16:07.840
<v Speaker 1>the bloodstream, right, and we're gonna talk about those symptoms

0:16:07.840 --> 0:16:33.640
<v Speaker 1>as promised, right after this, all.

0:16:33.600 --> 0:16:39.080
<v Speaker 2>Right, Chuck, let's bread yeah a little bit, let's talk symptoms. Okay,

0:16:39.880 --> 0:16:41.400
<v Speaker 2>you know what I need? I need one of those

0:16:41.480 --> 0:16:45.080
<v Speaker 2>like reads that bugs Bunny used to like hide in

0:16:45.120 --> 0:16:47.000
<v Speaker 2>the water when Almer Fudd was hunting him.

0:16:47.080 --> 0:16:47.320
<v Speaker 1>Uh huh.

0:16:47.800 --> 0:16:50.320
<v Speaker 2>I could just like get a long one and maybe

0:16:50.360 --> 0:16:52.800
<v Speaker 2>a crazy straw would be even better, and just like

0:16:52.920 --> 0:16:55.200
<v Speaker 2>pipe it out to the air duct right there.

0:16:55.360 --> 0:16:56.160
<v Speaker 1>That's a great idea.

0:16:56.280 --> 0:16:58.240
<v Speaker 2>What do you think we'll get everybody else sick except

0:16:58.280 --> 0:16:58.920
<v Speaker 2>you and Jeer.

0:17:00.120 --> 0:17:03.120
<v Speaker 1>So the symptoms sound a lot like a cold because

0:17:03.160 --> 0:17:06.440
<v Speaker 1>the symptoms are kind of the same. A cold is

0:17:06.840 --> 0:17:10.240
<v Speaker 1>usually not as fraught with potential complications and maybe a

0:17:10.280 --> 0:17:13.640
<v Speaker 1>little less severe, but they're pretty close which is why

0:17:13.640 --> 0:17:15.440
<v Speaker 1>you couldn't tell earlier if you had a colder fever

0:17:15.520 --> 0:17:16.400
<v Speaker 1>or flu.

0:17:16.520 --> 0:17:21.080
<v Speaker 2>Right now, but that fever, that's the big one. Apparently,

0:17:21.160 --> 0:17:23.479
<v Speaker 2>it's a big distinction between the Yeah.

0:17:23.520 --> 0:17:25.840
<v Speaker 1>I think that's kind of the way I just distinguish it.

0:17:25.880 --> 0:17:28.760
<v Speaker 2>Right, Yeah, And the cold colds are also caused by

0:17:28.840 --> 0:17:32.720
<v Speaker 2>viruses are caused by coronaviruses, which can there are types

0:17:32.760 --> 0:17:35.600
<v Speaker 2>of coronaviruses that are really bad that cause like MYRS

0:17:35.640 --> 0:17:38.480
<v Speaker 2>and SARS. Yeah, but for the most part, when you

0:17:38.560 --> 0:17:41.360
<v Speaker 2>catch a cold from a coronavirus, it's a low level virus,

0:17:41.800 --> 0:17:45.560
<v Speaker 2>or it's a rhinovirus. That's the other one that causes

0:17:45.600 --> 0:17:48.120
<v Speaker 2>the common cold, right, So it's just a different kind

0:17:48.119 --> 0:17:50.920
<v Speaker 2>of virus producing similar symptoms to a flu.

0:17:51.320 --> 0:17:54.520
<v Speaker 1>Do you remember when Peter Sarscard was on Saturday Night

0:17:54.600 --> 0:17:58.320
<v Speaker 1>Live years ago? He was, you know, the actor. Sure,

0:17:58.720 --> 0:18:01.600
<v Speaker 1>he was on there during the SARS when there was

0:18:01.600 --> 0:18:04.720
<v Speaker 1>that t SARS scare in the United States, and one

0:18:04.760 --> 0:18:07.720
<v Speaker 1>of their skits was he had developed the SARS Guard.

0:18:07.760 --> 0:18:12.320
<v Speaker 1>SARS Guard just basically a surgical mask. But it was

0:18:12.320 --> 0:18:14.760
<v Speaker 1>just funny. They said Sarsgard Stars Guard like thirty times

0:18:14.760 --> 0:18:15.640
<v Speaker 1>and I laughed every time.

0:18:17.240 --> 0:18:19.960
<v Speaker 2>I think his younger brothers was Pennywise, the clown in

0:18:20.000 --> 0:18:20.879
<v Speaker 2>the IT movie.

0:18:20.920 --> 0:18:22.320
<v Speaker 1>Right, Oh, I don't know.

0:18:22.600 --> 0:18:24.800
<v Speaker 2>I'm pretty sure that was a Sars guard and he

0:18:24.960 --> 0:18:27.960
<v Speaker 2>is amazing. Yeah have you seen it?

0:18:28.800 --> 0:18:29.000
<v Speaker 1>No?

0:18:29.280 --> 0:18:31.000
<v Speaker 2>Oh, you got to see it. You're gonna love it.

0:18:31.040 --> 0:18:33.280
<v Speaker 1>Now. Was he a Sar's guard or a scars Guard?

0:18:33.800 --> 0:18:36.520
<v Speaker 2>Oh? God, I didn't know there were two different things.

0:18:36.600 --> 0:18:39.720
<v Speaker 1>Well, there are the scars Guards, which is like Stellin'

0:18:39.760 --> 0:18:43.240
<v Speaker 1>scarsguard is the dad, okay, and then the son was

0:18:43.320 --> 0:18:48.360
<v Speaker 1>the dude on True Blood the vampire show, and then

0:18:48.480 --> 0:18:53.200
<v Speaker 1>recently on that pretty Little Liars I think one with

0:18:53.280 --> 0:18:56.679
<v Speaker 1>Nicole Kidman, Okay, that's Alexander scars Guard.

0:18:56.800 --> 0:18:59.280
<v Speaker 2>I think that might be him. Is sars Guard the

0:18:59.320 --> 0:19:04.160
<v Speaker 2>one who's in Fire Starza? No, who is that Peter

0:19:04.240 --> 0:19:04.840
<v Speaker 2>sars Card?

0:19:05.640 --> 0:19:08.240
<v Speaker 1>Yeah, that's another dude. What is up with all these guys?

0:19:08.480 --> 0:19:11.120
<v Speaker 2>So are you sure you're not just dropping the kof

0:19:11.160 --> 0:19:13.800
<v Speaker 2>of Peter's scars Guard?

0:19:14.760 --> 0:19:18.800
<v Speaker 1>All right, here's the deal. Okay, the guy in Fargo, Man,

0:19:18.840 --> 0:19:21.640
<v Speaker 1>this is such a bad sidetrack already, it's pretty bad.

0:19:21.720 --> 0:19:23.560
<v Speaker 1>The guy in Fargo was Peter Stormyre.

0:19:24.240 --> 0:19:26.800
<v Speaker 2>Okay, so he's not even in the equation.

0:19:26.960 --> 0:19:30.280
<v Speaker 1>Then no, but I definitely know that there is Peter

0:19:30.640 --> 0:19:34.480
<v Speaker 1>sars Guard okay, because he either was or is married

0:19:34.480 --> 0:19:35.400
<v Speaker 1>to Maggie Gillenhall.

0:19:36.520 --> 0:19:39.520
<v Speaker 2>Oh yeah, I guess I knew that Peter sars Guard.

0:19:39.840 --> 0:19:43.399
<v Speaker 1>Okay, and then they're stelling an Alexander scars Guard and

0:19:43.480 --> 0:19:44.800
<v Speaker 1>I don't know who it the clown was.

0:19:45.840 --> 0:19:47.920
<v Speaker 2>It's Bill scars Guard.

0:19:47.880 --> 0:19:50.120
<v Speaker 1>And is he related to the scars Guards?

0:19:50.880 --> 0:19:51.399
<v Speaker 2>I guess so.

0:19:51.760 --> 0:19:51.920
<v Speaker 1>Yeah.

0:19:51.960 --> 0:19:53.360
<v Speaker 2>I believe he's the youngest of them.

0:19:53.440 --> 0:19:53.760
<v Speaker 1>Okay.

0:19:54.240 --> 0:19:56.600
<v Speaker 2>Oh, I'm sorry. I was wrong. It was Tim Curry

0:19:56.600 --> 0:19:57.280
<v Speaker 2>I was talking about.

0:19:58.600 --> 0:20:00.800
<v Speaker 1>No, Actually we didn't know. Looks stuff up. But I

0:20:00.840 --> 0:20:04.040
<v Speaker 1>didn't look that up because the headline here says Alexander

0:20:04.080 --> 0:20:09.520
<v Speaker 1>Scarsgard's reaction to his brother Bill's clown costume.

0:20:09.840 --> 0:20:14.920
<v Speaker 2>Yeah, it's good his acting, it goes way beyond the costume.

0:20:14.960 --> 0:20:17.119
<v Speaker 2>They did good with the costume, but it was doing that.

0:20:17.240 --> 0:20:19.040
<v Speaker 2>Oh yeah, it was good.

0:20:19.240 --> 0:20:21.240
<v Speaker 1>I know there were so many people screaming at their phones,

0:20:21.280 --> 0:20:22.560
<v Speaker 1>but I think we finally got it right.

0:20:23.040 --> 0:20:26.680
<v Speaker 2>Yeah, sorry about that everybody. I also want to apologize

0:20:26.680 --> 0:20:29.720
<v Speaker 2>for any medical students who are being forced to listen

0:20:29.760 --> 0:20:32.840
<v Speaker 2>to this as part of their class. Hopefully your instructor

0:20:32.880 --> 0:20:34.120
<v Speaker 2>fast forwarded through that part.

0:20:34.280 --> 0:20:37.240
<v Speaker 1>All right, fact this all got started with Stars Guard

0:20:37.280 --> 0:20:37.919
<v Speaker 1>Stars Guards.

0:20:38.840 --> 0:20:41.600
<v Speaker 2>Oh yeah, that's right, because that's from the coronavirus. This

0:20:41.720 --> 0:20:44.280
<v Speaker 2>is the influenza virus we're talking about that creates this

0:20:44.400 --> 0:20:49.360
<v Speaker 2>inflammation which is your immune response right in your lungs.

0:20:49.000 --> 0:20:53.480
<v Speaker 1>That's correct. And the symptoms like a cold are coughing, sneezing,

0:20:53.520 --> 0:20:55.600
<v Speaker 1>that the fever which is different, like we said, with

0:20:55.640 --> 0:20:58.840
<v Speaker 1>the flu, achy body which usually comes with that fever,

0:20:59.480 --> 0:21:02.160
<v Speaker 1>and then Josh's running nose and congestion that you can

0:21:02.200 --> 0:21:04.040
<v Speaker 1>hear in your overall lethargy.

0:21:04.960 --> 0:21:07.760
<v Speaker 2>Yeah, I am a little under the weather, I guess

0:21:07.840 --> 0:21:09.280
<v Speaker 2>is a good way to put it. I can tell.

0:21:10.359 --> 0:21:13.680
<v Speaker 2>So those are just standard flu symptoms. You can have

0:21:13.840 --> 0:21:18.960
<v Speaker 2>secondary symptoms from complications of the flu. Right. One thing

0:21:19.000 --> 0:21:22.639
<v Speaker 2>that has long gone hand in hand with the flu

0:21:23.200 --> 0:21:26.600
<v Speaker 2>as far as like death from flu complications goes is

0:21:26.640 --> 0:21:27.760
<v Speaker 2>bacterial pneumonia.

0:21:27.880 --> 0:21:28.720
<v Speaker 1>Yeah. That's good.

0:21:29.000 --> 0:21:32.000
<v Speaker 2>And for a very long time science wasn't quite sure

0:21:32.080 --> 0:21:36.959
<v Speaker 2>why that why you were just so susceptible to bacterial

0:21:37.000 --> 0:21:40.119
<v Speaker 2>infections when you were battling the flu, and they figured

0:21:40.119 --> 0:21:44.199
<v Speaker 2>it out. It's actually your body's immune response that is

0:21:44.240 --> 0:21:47.000
<v Speaker 2>responsible for it, right, right, So when you have the

0:21:47.040 --> 0:21:49.080
<v Speaker 2>flu and your body starts to battle it off and

0:21:49.119 --> 0:21:54.760
<v Speaker 2>you get a fever and your lungs become inflamed, that's

0:21:54.880 --> 0:21:59.000
<v Speaker 2>that's your immune your immune system's response to the flu virus.

0:21:59.560 --> 0:22:02.960
<v Speaker 2>But when your body says, okay, calm down, everybody, let's

0:22:03.000 --> 0:22:07.120
<v Speaker 2>bring the temperature back down, and your body represses its

0:22:07.119 --> 0:22:11.199
<v Speaker 2>own immune response, it opens the door for bacteria that

0:22:11.359 --> 0:22:13.880
<v Speaker 2>normally it would be able to fight off, to take

0:22:13.920 --> 0:22:17.640
<v Speaker 2>advantage of this kind of naturally weakened state that your

0:22:17.680 --> 0:22:20.640
<v Speaker 2>immune system is in, and you can you're much more

0:22:20.680 --> 0:22:25.080
<v Speaker 2>susceptible the infections from bacteria, and that's where pneumonia comes from.

0:22:25.119 --> 0:22:28.960
<v Speaker 2>You can get viral pneumonia, but you usually get bacterial pneumonia.

0:22:29.480 --> 0:22:32.280
<v Speaker 2>And that's the stuff that people can die from because

0:22:32.600 --> 0:22:36.160
<v Speaker 2>that bacteria infects your air sex and your lungs, which

0:22:36.200 --> 0:22:39.960
<v Speaker 2>feel a fluid and puss and blood, and you die

0:22:40.000 --> 0:22:44.480
<v Speaker 2>from choking on bloody froth that fills up your airway. Yeah,

0:22:44.119 --> 0:22:45.560
<v Speaker 2>it's a bad jam man.

0:22:46.600 --> 0:22:50.760
<v Speaker 1>Severe dehydration is another secondary symptom of the flu. That's why,

0:22:50.760 --> 0:22:53.200
<v Speaker 1>of course you always want to drink plenty of water

0:22:53.280 --> 0:22:54.520
<v Speaker 1>when you have a cold or flu.

0:22:54.760 --> 0:22:56.840
<v Speaker 2>I look that one up too, Chuck, Because if you

0:22:56.840 --> 0:22:59.440
<v Speaker 2>think about it, why why would you be dehydrated from

0:22:59.480 --> 0:23:03.439
<v Speaker 2>the flu. It's from sweating, yeah, sure, your nose running.

0:23:03.560 --> 0:23:05.960
<v Speaker 1>Yeah, it's just leaking fluids.

0:23:06.080 --> 0:23:09.080
<v Speaker 2>You you are, and like they start to add up

0:23:09.080 --> 0:23:11.440
<v Speaker 2>and all of a sudden you're dehydrated before you even

0:23:11.480 --> 0:23:11.800
<v Speaker 2>knew it.

0:23:12.000 --> 0:23:17.000
<v Speaker 1>That's right. Ear infections, especially if you're a kid, sinus issues.

0:23:17.480 --> 0:23:20.200
<v Speaker 1>Emily always gets bad sinus problems along with this stuff.

0:23:20.440 --> 0:23:22.240
<v Speaker 2>I know she was starting to get a little Sniffley,

0:23:22.320 --> 0:23:25.800
<v Speaker 2>is she sick? She did get sick, that poor lady. Yeah,

0:23:25.840 --> 0:23:28.480
<v Speaker 2>New York Man. Yeah, it killed everyone I love.

0:23:31.119 --> 0:23:33.960
<v Speaker 1>And then if you like, in Emily's case, she's slightly asthmatic,

0:23:34.720 --> 0:23:37.600
<v Speaker 1>But if you are asthmatic, you're like diabetes, it can

0:23:37.800 --> 0:23:38.800
<v Speaker 1>make that stuff worse.

0:23:40.200 --> 0:23:43.879
<v Speaker 2>Yeah, she doesn't have diabetes, right, No, Well, the reason

0:23:43.920 --> 0:23:48.719
<v Speaker 2>diabetes is comorbid with the flu or is problematic when

0:23:48.760 --> 0:23:52.280
<v Speaker 2>you have with the flu, is because type one diabetes,

0:23:52.400 --> 0:23:58.399
<v Speaker 2>especially is an autoimmune disease, So your immune systems already repressed,

0:23:58.960 --> 0:24:02.879
<v Speaker 2>I guess yeah, And then heart conditions can be exacerbated

0:24:02.880 --> 0:24:07.080
<v Speaker 2>by it because you're getting less oxygen from your lungs

0:24:07.119 --> 0:24:10.480
<v Speaker 2>into your bloodstream, which strains the heart. And if it's

0:24:10.480 --> 0:24:12.960
<v Speaker 2>already weak, people have heart attacks from the flu if

0:24:12.960 --> 0:24:16.600
<v Speaker 2>they already have a heart condition. Isn't that crazy? Yeah, again,

0:24:16.680 --> 0:24:17.640
<v Speaker 2>it's a bad jam.

0:24:18.080 --> 0:24:21.520
<v Speaker 1>Well, actually, we in the episode coming up about the

0:24:21.840 --> 0:24:26.440
<v Speaker 1>silly one about the ten Cursed movies. Remember the little

0:24:26.480 --> 0:24:31.720
<v Speaker 1>girl from Poltergeis died from at twelve from a heart

0:24:31.720 --> 0:24:33.840
<v Speaker 1>attack brought on by the flu.

0:24:34.320 --> 0:24:37.880
<v Speaker 2>Yeah right, yeah, or she had like a stomach blockage.

0:24:37.880 --> 0:24:39.879
<v Speaker 2>They initially diagnosed it as the flu.

0:24:40.359 --> 0:24:43.119
<v Speaker 1>Oh okay, but I thought it was not never like

0:24:43.160 --> 0:24:43.879
<v Speaker 1>a virus like that.

0:24:44.200 --> 0:24:46.800
<v Speaker 2>I don't think so. I think they mistook it all. Well,

0:24:46.840 --> 0:24:49.480
<v Speaker 2>then forget all that, but people do, so your point

0:24:49.560 --> 0:24:51.240
<v Speaker 2>still remains correct.

0:24:51.359 --> 0:24:57.560
<v Speaker 1>Okay, So how you get the flu? Is this? Like

0:24:57.600 --> 0:25:00.280
<v Speaker 1>you said, it's generally about November through March. Jane in

0:25:00.320 --> 0:25:03.560
<v Speaker 1>February tend to be the worst of it here in

0:25:03.600 --> 0:25:08.520
<v Speaker 1>the United States, And as we mentioned, offices and schools,

0:25:08.600 --> 0:25:14.119
<v Speaker 1>especially because children are filthy monsters who just don't wash hands,

0:25:14.119 --> 0:25:16.840
<v Speaker 1>and they breathe on each other and touch each other,

0:25:16.880 --> 0:25:19.400
<v Speaker 1>and they don't cover their mouths when they call for sneeze.

0:25:19.440 --> 0:25:21.360
<v Speaker 2>But it's pretty cute when they hug each other.

0:25:21.600 --> 0:25:22.520
<v Speaker 1>It's very cute.

0:25:22.600 --> 0:25:25.600
<v Speaker 2>Actually, it's worth it's worth all the sickness in the world.

0:25:25.720 --> 0:25:29.680
<v Speaker 1>It's pretty great. But that's the reason that kids tend

0:25:29.720 --> 0:25:31.880
<v Speaker 1>to spread it more because as much as you try

0:25:31.920 --> 0:25:33.399
<v Speaker 1>and teach them to cover their mouth when they call

0:25:33.560 --> 0:25:35.679
<v Speaker 1>and sneeze and wash their hands a lot, it's just

0:25:35.680 --> 0:25:37.720
<v Speaker 1>not really on their radar like it is for adults.

0:25:38.119 --> 0:25:43.800
<v Speaker 2>No, you know, because they are dirty, dirty, dirty creatures.

0:25:44.280 --> 0:25:46.080
<v Speaker 1>And then you know, the kid then in turn brings

0:25:46.119 --> 0:25:49.080
<v Speaker 1>it home and the family gets infected pretty quickly because

0:25:49.840 --> 0:25:53.080
<v Speaker 1>try as you might, there's just a lot of close

0:25:53.160 --> 0:25:55.399
<v Speaker 1>contact with kids that you can't avoid. And even if

0:25:55.400 --> 0:25:58.359
<v Speaker 1>you're washing your hands, they will find a way to

0:25:58.400 --> 0:25:58.879
<v Speaker 1>infect you.

0:25:59.800 --> 0:26:02.639
<v Speaker 2>Right, And if you go even further back, there's an

0:26:02.720 --> 0:26:07.280
<v Speaker 2>even earlier origin before kids picking it up at daycare

0:26:07.400 --> 0:26:14.439
<v Speaker 2>or preschool. For the flu, usually it comes from other animals.

0:26:14.640 --> 0:26:18.440
<v Speaker 2>We were finding, right, Yes, frequently birds, like we were saying, right,

0:26:18.960 --> 0:26:21.679
<v Speaker 2>And they used to think that for a human to

0:26:21.760 --> 0:26:27.840
<v Speaker 2>catch a flu from a bird, especially, that flu had

0:26:27.840 --> 0:26:30.399
<v Speaker 2>to show up in a mixing vessel. Usually a pig

0:26:31.080 --> 0:26:34.320
<v Speaker 2>which was capable of taking it could be infected by

0:26:34.320 --> 0:26:38.160
<v Speaker 2>a bird flu and a human flu and flu viruses

0:26:38.240 --> 0:26:44.280
<v Speaker 2>have this amazing talent called reassortment, where a flu strain

0:26:44.720 --> 0:26:47.920
<v Speaker 2>and another flu strain can get together and be like, oh, hey,

0:26:48.000 --> 0:26:52.159
<v Speaker 2>you have eight proteins that make up your RNA. I

0:26:52.240 --> 0:26:54.760
<v Speaker 2>do too, Let's mix and match and see what happens.

0:26:55.280 --> 0:26:57.120
<v Speaker 2>And they thought for a long time that this really

0:26:57.160 --> 0:26:59.760
<v Speaker 2>only took place in pigs and then out would come

0:26:59.840 --> 0:27:02.200
<v Speaker 2>a new super virus that no one had ever seen

0:27:02.240 --> 0:27:06.679
<v Speaker 2>before that humans could catch. But from Southeast Asia, people

0:27:06.680 --> 0:27:11.240
<v Speaker 2>being in close contact with infected birds, especially like in

0:27:11.240 --> 0:27:14.679
<v Speaker 2>the poultry industry or something, there have been cases that

0:27:14.760 --> 0:27:19.600
<v Speaker 2>started in the nineties of AVM flu coming directly from

0:27:19.680 --> 0:27:22.119
<v Speaker 2>birds to humans, so that that theory went out in

0:27:22.119 --> 0:27:25.399
<v Speaker 2>the window. Yeah, and that's what set off those fears

0:27:25.400 --> 0:27:27.879
<v Speaker 2>of a bird flu pandemic that we lived with for

0:27:27.920 --> 0:27:28.880
<v Speaker 2>many years.

0:27:29.560 --> 0:27:32.760
<v Speaker 1>Yeah, that's right as far as and you know that

0:27:32.840 --> 0:27:34.560
<v Speaker 1>a lot of that was just spread from bird poop.

0:27:35.560 --> 0:27:39.440
<v Speaker 2>Yeah, and it scared people because that those bird flus

0:27:39.520 --> 0:27:42.600
<v Speaker 2>are no joke, Like they have like a sixty percent

0:27:42.680 --> 0:27:46.720
<v Speaker 2>mortality rate sixty percent. Six out of ten people who

0:27:46.760 --> 0:27:52.040
<v Speaker 2>come down with H five N one bird flu die right. Luckily,

0:27:52.080 --> 0:27:55.199
<v Speaker 2>it's really really difficult to catch it even when you

0:27:55.240 --> 0:27:58.240
<v Speaker 2>are around sick birds. It doesn't very frequently make the

0:27:58.320 --> 0:28:00.719
<v Speaker 2>jump to humans, but it can, is what they what

0:28:00.760 --> 0:28:01.280
<v Speaker 2>they found.

0:28:01.920 --> 0:28:05.840
<v Speaker 1>Yeah, as far as the regular flu, the garden variety

0:28:05.840 --> 0:28:11.160
<v Speaker 1>flu that we're talking about mainly here, it spreads from well,

0:28:11.200 --> 0:28:14.920
<v Speaker 1>like we said, from touching stuff, from coughing and sneezing.

0:28:14.920 --> 0:28:17.520
<v Speaker 1>When you cough and sneeze, even even if you think

0:28:17.560 --> 0:28:21.919
<v Speaker 1>you're covering your mouth pretty well, there may be little

0:28:22.119 --> 0:28:27.600
<v Speaker 1>little fluids squirting out between your fingers up to a

0:28:27.640 --> 0:28:34.639
<v Speaker 1>few feet. It's in the air around you. That stuff

0:28:34.640 --> 0:28:37.440
<v Speaker 1>can travel, you know. So if that lands on a doorknob,

0:28:37.800 --> 0:28:39.960
<v Speaker 1>or if someone covers her mouth like a like a

0:28:40.160 --> 0:28:44.720
<v Speaker 1>normal and then opens a door or borrows a stapler

0:28:45.240 --> 0:28:48.240
<v Speaker 1>or whatever, it's going to be on that door knob

0:28:48.320 --> 0:28:50.600
<v Speaker 1>and then you touch it. And that's why like hand

0:28:50.760 --> 0:28:53.480
<v Speaker 1>washing by the sick and by the non sick is

0:28:53.480 --> 0:28:55.280
<v Speaker 1>so crucial. Yeah.

0:28:55.320 --> 0:28:57.840
<v Speaker 2>And if you're like having an anxious day at work

0:28:57.840 --> 0:28:59.920
<v Speaker 2>and you're doing your normal thing of chewing on your

0:28:59.880 --> 0:29:03.400
<v Speaker 2>stapler to relieve anxiety and the guy who borrowed it

0:29:03.440 --> 0:29:04.960
<v Speaker 2>was sick, your toast.

0:29:05.160 --> 0:29:08.200
<v Speaker 1>You are toast. And as you mentioned earlier, bears repeating

0:29:08.800 --> 0:29:11.560
<v Speaker 1>you can be sick a day before symptoms, and you

0:29:11.600 --> 0:29:14.520
<v Speaker 1>can or you can be contagious a day before symptoms

0:29:14.560 --> 0:29:19.560
<v Speaker 1>and still remain contagious up to seven days after the

0:29:19.600 --> 0:29:23.240
<v Speaker 1>symptoms start. Right, So even if you feel better after

0:29:23.960 --> 0:29:26.960
<v Speaker 1>day four, you could still be spreading that junk around

0:29:27.000 --> 0:29:28.240
<v Speaker 1>for a few more days. Right.

0:29:28.320 --> 0:29:30.560
<v Speaker 2>And they say that even after you feel better, you

0:29:30.600 --> 0:29:32.960
<v Speaker 2>should stay in bed an extra day because again, your

0:29:32.960 --> 0:29:38.000
<v Speaker 2>immune system is compromised and you are are like, you

0:29:38.000 --> 0:29:40.320
<v Speaker 2>can catch other stuff, so you want to be careful.

0:29:40.400 --> 0:29:42.280
<v Speaker 2>That extra day really pays.

0:29:42.000 --> 0:29:44.280
<v Speaker 1>Off, and that's when you just lay in bed and

0:29:44.520 --> 0:29:45.760
<v Speaker 1>watch Stranger Things.

0:29:45.560 --> 0:29:47.800
<v Speaker 2>Too, Right, I haven't seen it you? Is it good?

0:29:48.040 --> 0:29:49.440
<v Speaker 1>Yeah, we just finished it last night.

0:29:49.480 --> 0:29:49.760
<v Speaker 2>Cool.

0:29:50.200 --> 0:29:51.600
<v Speaker 1>Did you see the first season? Yeah?

0:29:51.600 --> 0:29:52.880
<v Speaker 2>Oh yeah, yeah, that was great.

0:29:53.160 --> 0:29:56.120
<v Speaker 1>Season two is just as great, if not better.

0:29:56.360 --> 0:29:58.440
<v Speaker 2>Wow. I'm glad to say that too.

0:29:58.560 --> 0:30:00.280
<v Speaker 1>I was a little nervous, you know, because it was

0:30:00.280 --> 0:30:04.000
<v Speaker 1>something I loved and it's like, oh man, it's easy too.

0:30:04.000 --> 0:30:04.640
<v Speaker 1>A lot of pressure.

0:30:04.840 --> 0:30:07.320
<v Speaker 2>Well, yeah, that's how it happens. The sophomore season is

0:30:07.440 --> 0:30:11.600
<v Speaker 2>very frequently like everyone's aware of the success of the

0:30:11.640 --> 0:30:13.920
<v Speaker 2>show and what people are saying about and they try

0:30:13.960 --> 0:30:17.920
<v Speaker 2>to adapt to the expectations rather than continuing on doing

0:30:17.920 --> 0:30:20.280
<v Speaker 2>what they were doing before. But good for you guys.

0:30:20.320 --> 0:30:21.120
<v Speaker 2>Stranger things.

0:30:21.200 --> 0:30:23.800
<v Speaker 1>Yeah so great. I want to get those Duffer brothers

0:30:23.840 --> 0:30:25.160
<v Speaker 1>on movie Crush.

0:30:25.320 --> 0:30:26.280
<v Speaker 2>Oh yeah, it'd be cool.

0:30:26.320 --> 0:30:27.160
<v Speaker 1>Those guys'd be great.

0:30:27.680 --> 0:30:29.760
<v Speaker 2>Should we take a break, yeah, I think so.

0:30:29.880 --> 0:30:31.520
<v Speaker 1>All right, we'll come back and talk a little bit

0:30:31.520 --> 0:30:56.760
<v Speaker 1>about pandemics, all.

0:30:56.720 --> 0:31:00.480
<v Speaker 2>Right, Chuck. So we were talking about how seasonal flu

0:31:00.680 --> 0:31:05.560
<v Speaker 2>has seasons. That's why it's called seasonal flu. Right, That's

0:31:05.720 --> 0:31:10.280
<v Speaker 2>that's I guess one classification of flus. There's also a

0:31:10.280 --> 0:31:12.800
<v Speaker 2>pandemic flu, and the same kind of flu virus can

0:31:12.880 --> 0:31:15.520
<v Speaker 2>be a pandemic flu or a seasonal flu. And I

0:31:15.520 --> 0:31:18.640
<v Speaker 2>think usually the way it happens is a new virus

0:31:18.720 --> 0:31:22.800
<v Speaker 2>will emerge from say like livestock or poultry or something

0:31:22.840 --> 0:31:26.760
<v Speaker 2>like that and infect humans. And if it's totally novel

0:31:26.920 --> 0:31:30.160
<v Speaker 2>where no human has ever encountered a flu of this

0:31:30.280 --> 0:31:33.720
<v Speaker 2>type before, it can just lay waste to people. It

0:31:33.720 --> 0:31:35.560
<v Speaker 2>can kill a lot of people, It can infect a

0:31:35.560 --> 0:31:38.840
<v Speaker 2>lot of people that can spread the world. And when

0:31:38.880 --> 0:31:43.200
<v Speaker 2>that happens, it becomes classified as a pandemic flu. After

0:31:43.480 --> 0:31:46.520
<v Speaker 2>a couple of rounds around the world, people will have

0:31:46.560 --> 0:31:49.040
<v Speaker 2>started to develop an immunity to it, but it'll still

0:31:49.080 --> 0:31:53.200
<v Speaker 2>be passed around. And so for the decade or so,

0:31:53.440 --> 0:31:56.200
<v Speaker 2>it can be the predominant strain of the flu, but

0:31:56.280 --> 0:31:59.600
<v Speaker 2>it'll be it'll have changed over to a seasonal type

0:31:59.640 --> 0:32:03.680
<v Speaker 2>of flu. So it's almost like that the pandemic versus

0:32:03.720 --> 0:32:08.680
<v Speaker 2>seasonal type flu describes how contagious it is and how

0:32:08.760 --> 0:32:11.680
<v Speaker 2>virulent it is. I think that's the big distinction.

0:32:12.280 --> 0:32:14.280
<v Speaker 1>Yeah, And I think also in a pandemic, doesn't that

0:32:14.320 --> 0:32:16.760
<v Speaker 1>mean it is left the country?

0:32:16.880 --> 0:32:18.760
<v Speaker 2>Yeah, I think that is kind of one of the

0:32:18.800 --> 0:32:19.880
<v Speaker 2>indicators of it too.

0:32:20.040 --> 0:32:24.160
<v Speaker 1>Yeah. Nineteen eighteen, that was These numbers are staggering. This

0:32:24.280 --> 0:32:27.800
<v Speaker 1>is the worst flu pandemic and world history in nineteen

0:32:27.880 --> 0:32:32.200
<v Speaker 1>eighteen for I don't know what months exactly, but nineteen

0:32:32.240 --> 0:32:36.960
<v Speaker 1>eighteen and nineteen and it killed more than twenty million

0:32:37.640 --> 0:32:39.480
<v Speaker 1>people around the world.

0:32:39.320 --> 0:32:41.920
<v Speaker 2>And it killed most of those people actually in four

0:32:41.960 --> 0:32:43.680
<v Speaker 2>months from September to December.

0:32:43.960 --> 0:32:47.600
<v Speaker 1>Isn't that crazy? More lives were lost than all twentyth

0:32:47.600 --> 0:32:49.800
<v Speaker 1>century wars combined to the flu.

0:32:50.320 --> 0:32:53.400
<v Speaker 2>Yeah, you said twenty million, twenty.

0:32:53.120 --> 0:32:55.720
<v Speaker 1>Million worldwide, about half a million in the United States.

0:32:55.840 --> 0:32:59.840
<v Speaker 2>I saw in many reputable places fifty million people died

0:33:00.120 --> 0:33:00.680
<v Speaker 2>around the world.

0:33:00.800 --> 0:33:02.280
<v Speaker 1>It's just it's staggering.

0:33:02.600 --> 0:33:04.400
<v Speaker 2>Yeah, And that was like right at the end of

0:33:04.400 --> 0:33:07.880
<v Speaker 2>World War One and just came out of nowhere. And

0:33:07.960 --> 0:33:10.560
<v Speaker 2>one of the other really noteworthy things about it that

0:33:10.680 --> 0:33:14.800
<v Speaker 2>just baffled people was it was killing like healthy people

0:33:15.120 --> 0:33:18.240
<v Speaker 2>under the age of like twenty two, twenty three, twenty four,

0:33:18.840 --> 0:33:22.000
<v Speaker 2>like just healthy young people killed by the flu. A

0:33:22.000 --> 0:33:25.320
<v Speaker 2>lot of them died from pneumonia. And they finally figured

0:33:25.360 --> 0:33:29.120
<v Speaker 2>out that it was because it had been about twenty

0:33:29.200 --> 0:33:32.800
<v Speaker 2>something years since a flu resembling that type of strain

0:33:32.880 --> 0:33:35.920
<v Speaker 2>had made the rounds, so people under say, like age

0:33:35.920 --> 0:33:38.800
<v Speaker 2>twenty five had never been exposed to it. So it

0:33:38.840 --> 0:33:42.640
<v Speaker 2>was a novel flu which just leveled the people it

0:33:42.720 --> 0:33:45.880
<v Speaker 2>was exposed to had never never encountered something like it before.

0:33:46.120 --> 0:33:50.200
<v Speaker 1>Yeah, it's I mean, it's scared to think about. I mean, truly,

0:33:50.240 --> 0:33:52.120
<v Speaker 1>that couldn't happen today, could it? Or could it?

0:33:52.240 --> 0:33:52.400
<v Speaker 2>Oh?

0:33:52.520 --> 0:33:56.560
<v Speaker 1>Yeah, yeah, sure, man, you think that we could had

0:33:56.600 --> 0:33:58.240
<v Speaker 1>something like that off these days?

0:33:59.040 --> 0:34:01.360
<v Speaker 2>Do you know, like a of the population of the

0:34:01.360 --> 0:34:05.240
<v Speaker 2>world was infected with that flu that year? Wow, isn't

0:34:05.240 --> 0:34:05.920
<v Speaker 2>that crazy?

0:34:06.000 --> 0:34:06.960
<v Speaker 1>I know, that's hard to believe.

0:34:07.080 --> 0:34:11.480
<v Speaker 2>Yeah, that can totally happen. It's a real concern, all right.

0:34:11.560 --> 0:34:15.520
<v Speaker 1>So as far as your risk of getting the flu,

0:34:16.080 --> 0:34:19.600
<v Speaker 1>if you're a kid, like there's different risk groups like

0:34:19.680 --> 0:34:23.640
<v Speaker 1>high risk, low risk, whatever, medium or average risk. But

0:34:23.680 --> 0:34:27.400
<v Speaker 1>if you're under two years old, your little immune system

0:34:27.520 --> 0:34:30.040
<v Speaker 1>isn't quite smart enough yet to know how to fight

0:34:30.080 --> 0:34:33.760
<v Speaker 1>things off, so you're definitely more at risk. And as always,

0:34:34.040 --> 0:34:37.239
<v Speaker 1>what affects the children also affect the elderly. So if

0:34:37.239 --> 0:34:41.879
<v Speaker 1>you're over sixty five seniors is elderly wrong to say,

0:34:42.239 --> 0:34:43.080
<v Speaker 1>I think elderly?

0:34:43.239 --> 0:34:44.839
<v Speaker 2>Technically eighty one? Oh?

0:34:44.880 --> 0:34:46.760
<v Speaker 1>Really? Yeah, all right, so we'll go with seniors.

0:34:47.600 --> 0:34:51.719
<v Speaker 2>Seniors, active senior adults who have decades left ahead of them,

0:34:51.880 --> 0:34:52.399
<v Speaker 2>that's right.

0:34:53.719 --> 0:34:56.600
<v Speaker 1>Who else, anyone who has any kind of chronic like

0:34:56.640 --> 0:34:59.720
<v Speaker 1>I mentioned asthma or diabetes, any kind of chronic condition,

0:35:00.520 --> 0:35:03.799
<v Speaker 1>if you're pregnant, if you work in a hospital or

0:35:03.800 --> 0:35:06.040
<v Speaker 1>a doctor's office or nursing home.

0:35:06.360 --> 0:35:08.920
<v Speaker 2>Nursing home is not just people who work there, but

0:35:08.960 --> 0:35:13.400
<v Speaker 2>the residents too are in a really vulnerable position. Because

0:35:13.400 --> 0:35:16.640
<v Speaker 2>they are in the elderly age range, their immune systems

0:35:16.640 --> 0:35:19.160
<v Speaker 2>are pretty compromised. If they're in a nursing home, they're

0:35:19.200 --> 0:35:22.560
<v Speaker 2>probably ill already and then they're living in close quarters

0:35:22.560 --> 0:35:24.880
<v Speaker 2>with other people who are ill. That's a that's a

0:35:24.880 --> 0:35:25.880
<v Speaker 2>recipe for a disaster.

0:35:26.200 --> 0:35:29.640
<v Speaker 1>Yeah, sure is. It's also a recipe for tapioca pudding.

0:35:30.360 --> 0:35:35.520
<v Speaker 1>It is the best around remedy wise. And we'll talk

0:35:35.520 --> 0:35:38.360
<v Speaker 1>about vaccinations here in a minute, because I thought that

0:35:38.440 --> 0:35:40.200
<v Speaker 1>was kind of one of the most interesting parts of this.

0:35:41.640 --> 0:35:44.560
<v Speaker 1>But as far as remedies, if you get the flu,

0:35:45.040 --> 0:35:49.359
<v Speaker 1>it's a it's a virus. So you can't take anti biotics. No,

0:35:49.920 --> 0:35:52.040
<v Speaker 1>you can't take a pill that's going to cure you.

0:35:52.840 --> 0:35:55.560
<v Speaker 1>There are some anti viral drugs, which I've never tried

0:35:55.600 --> 0:35:56.759
<v Speaker 1>any of these of you.

0:35:56.800 --> 0:35:58.239
<v Speaker 2>No, no, no.

0:35:58.960 --> 0:36:02.080
<v Speaker 1>I tried zycamlast year once. I think that's for colds.

0:36:02.360 --> 0:36:04.560
<v Speaker 2>Yeah, I thought that was like discredited.

0:36:05.040 --> 0:36:07.040
<v Speaker 1>Well, I mean I had a few people say, oh,

0:36:07.239 --> 0:36:08.880
<v Speaker 1>you know, you try as I can. It helps not

0:36:08.960 --> 0:36:09.759
<v Speaker 1>cut your cold faster.

0:36:10.080 --> 0:36:10.160
<v Speaker 2>Uh.

0:36:10.520 --> 0:36:15.200
<v Speaker 1>It killed my sense of taste and smell. Oh no,

0:36:15.600 --> 0:36:17.680
<v Speaker 1>for several days, to the point where I was scared.

0:36:17.880 --> 0:36:19.760
<v Speaker 2>I don't remember that. I'll bet you were scared.

0:36:19.920 --> 0:36:21.319
<v Speaker 1>Yeah, And I looked it up and it's a thing.

0:36:21.920 --> 0:36:23.520
<v Speaker 2>Oh I do remember that actually.

0:36:23.800 --> 0:36:24.240
<v Speaker 1>Yeah.

0:36:24.320 --> 0:36:28.080
<v Speaker 2>Yeah, that's just really unnerving. The idea of maybe it's permanent.

0:36:28.400 --> 0:36:31.319
<v Speaker 1>Yeah it was. It was pretty pretty freaky, yeah, I'll bet,

0:36:31.480 --> 0:36:34.279
<v Speaker 1>and super noticeable. It wasn't like a subtle thing.

0:36:34.719 --> 0:36:39.040
<v Speaker 2>You'd be like chilling, I miss you.

0:36:40.160 --> 0:36:43.080
<v Speaker 1>So that was my experience. I'm not making some sweeping

0:36:43.120 --> 0:36:45.000
<v Speaker 1>statement about that medication.

0:36:44.960 --> 0:36:46.000
<v Speaker 2>Way to see amen.

0:36:47.000 --> 0:36:50.160
<v Speaker 1>But there are antiviral drugs called there's one called tama

0:36:50.160 --> 0:36:54.960
<v Speaker 1>flu relenza flumidine a little on the nose if you ask.

0:36:54.840 --> 0:37:00.960
<v Speaker 2>Me flu stop, Well, any viral they seem like a

0:37:01.000 --> 0:37:04.239
<v Speaker 2>good idea, But they seem like a good idea under

0:37:04.280 --> 0:37:07.040
<v Speaker 2>the premise that seasonal flu strains were used to think.

0:37:07.200 --> 0:37:09.480
<v Speaker 2>They used to think that they died out at the

0:37:09.560 --> 0:37:12.719
<v Speaker 2>end of a season. Right, Well, they started tracking them,

0:37:12.719 --> 0:37:17.680
<v Speaker 2>like our global monitoring system is really top notch and

0:37:18.000 --> 0:37:20.680
<v Speaker 2>they can track flu around the world, and they've found

0:37:20.719 --> 0:37:23.319
<v Speaker 2>that seasonal flu at the end of the season in

0:37:23.360 --> 0:37:27.880
<v Speaker 2>North America, it just goes to South America. So since

0:37:28.280 --> 0:37:31.319
<v Speaker 2>since that's the case, when you use anti virals and

0:37:31.400 --> 0:37:34.919
<v Speaker 2>you're exposing these flus that go on to survive, you're

0:37:34.960 --> 0:37:39.359
<v Speaker 2>also training them evolutionarily speaking, to adapt so that those

0:37:39.719 --> 0:37:42.800
<v Speaker 2>antiviral drugs are useless against them. For people who really

0:37:42.840 --> 0:37:47.160
<v Speaker 2>need them. So, just like with antibiotics, using anti virals

0:37:47.360 --> 0:37:50.000
<v Speaker 2>just to cure a common flu or to shorten a

0:37:50.040 --> 0:37:53.240
<v Speaker 2>common flu is probably a bad idea when you're talking

0:37:53.239 --> 0:37:54.440
<v Speaker 2>about the whole population.

0:37:55.239 --> 0:37:57.520
<v Speaker 1>Yeah, and that's what they do. They they what they

0:37:57.520 --> 0:38:01.840
<v Speaker 1>try to do is just keep the red cellular spread

0:38:01.880 --> 0:38:06.160
<v Speaker 1>from happening as much as it can. Right, And that's

0:38:06.160 --> 0:38:07.319
<v Speaker 1>sort of the easiest way to say it.

0:38:08.080 --> 0:38:11.120
<v Speaker 2>Yeah. Yeah, there's there's one keeps them well to a

0:38:11.120 --> 0:38:13.920
<v Speaker 2>pair of them, keep them from replicating, and then another

0:38:13.960 --> 0:38:17.840
<v Speaker 2>one traps them inside to sell. Once they enter, it's like,

0:38:17.880 --> 0:38:20.320
<v Speaker 2>oh God, I can't get out, the door is locked,

0:38:20.320 --> 0:38:21.520
<v Speaker 2>and then death.

0:38:22.840 --> 0:38:26.160
<v Speaker 1>And they're all prescription drugs, right, if I'm not mistaken.

0:38:27.080 --> 0:38:30.600
<v Speaker 2>So vaccines are like pretty hot. They're like the hot

0:38:30.640 --> 0:38:32.600
<v Speaker 2>thing to do on a Friday night is to go

0:38:32.640 --> 0:38:33.920
<v Speaker 2>get a flu vaccine, right.

0:38:34.320 --> 0:38:39.120
<v Speaker 1>Yeah, I didn't get I didn't get flu shots for many, many,

0:38:39.120 --> 0:38:42.040
<v Speaker 1>many many years until I had a kid.

0:38:42.600 --> 0:38:45.120
<v Speaker 2>Yeah. And they say like if you especially if you

0:38:45.160 --> 0:38:47.800
<v Speaker 2>have a baby under six months of age, they can't

0:38:47.800 --> 0:38:53.680
<v Speaker 2>be vaccinated and so everyone around them should be vaccinated,

0:38:53.800 --> 0:38:57.040
<v Speaker 2>is the recommended recommendation from the CDC.

0:38:57.239 --> 0:39:00.920
<v Speaker 1>Yeah, like our close family, the grain and the abbas

0:39:01.640 --> 0:39:03.880
<v Speaker 1>all and the pop pops and the papas and the

0:39:03.920 --> 0:39:11.319
<v Speaker 1>poupas and the memangs and the momos. Yeah, yeah, Momo

0:39:11.360 --> 0:39:12.000
<v Speaker 1>got a flu shot.

0:39:12.120 --> 0:39:14.320
<v Speaker 2>That was nice of her. She's very kind.

0:39:15.239 --> 0:39:17.480
<v Speaker 1>So yeah, we all got flu shots. And I just

0:39:17.600 --> 0:39:19.640
<v Speaker 1>wasn't you know, I never got the flu much. I'd

0:39:19.640 --> 0:39:23.320
<v Speaker 1>never I didn't have a disbelief in the flu vaccine.

0:39:23.360 --> 0:39:25.719
<v Speaker 1>I was just like, yeah, I don't really need to

0:39:25.719 --> 0:39:26.279
<v Speaker 1>bother with that.

0:39:26.560 --> 0:39:28.799
<v Speaker 2>Yeah, that's kind of it was fine. Do you get

0:39:28.840 --> 0:39:31.160
<v Speaker 2>them now though? Is it a habit of yours now?

0:39:31.320 --> 0:39:33.799
<v Speaker 1>Well? Yeah, now, just they just sort of recommend it.

0:39:33.800 --> 0:39:36.799
<v Speaker 1>When you have kids up up until they're a certain age,

0:39:36.840 --> 0:39:39.319
<v Speaker 1>you should get vaccinated as a family.

0:39:39.239 --> 0:39:41.719
<v Speaker 2>Right, And when you have kids, if you get them vaccinated,

0:39:41.760 --> 0:39:45.479
<v Speaker 2>you once they're able to be vaccinated again under six months,

0:39:45.520 --> 0:39:48.959
<v Speaker 2>they say, no, no, no, don't do that. When they're

0:39:49.360 --> 0:39:52.000
<v Speaker 2>young though, and you're getting them vaccinated, they need to

0:39:52.000 --> 0:39:55.440
<v Speaker 2>be vaccinated twice, like a month apart. Yes, And so

0:39:55.600 --> 0:39:58.960
<v Speaker 2>with flu vaccines in general, they recommend that you get

0:39:58.960 --> 0:40:01.920
<v Speaker 2>it as early in the season is possible because it

0:40:01.960 --> 0:40:05.080
<v Speaker 2>takes about two weeks for that to take effect. So

0:40:05.200 --> 0:40:07.040
<v Speaker 2>with a kid, then I guess you would want to

0:40:07.080 --> 0:40:11.200
<v Speaker 2>get them, so that six weeks before the flu season,

0:40:11.239 --> 0:40:14.720
<v Speaker 2>I don't know, or there is that second one pretty

0:40:14.760 --> 0:40:17.239
<v Speaker 2>much like, okay, now it's taking effect. So is that

0:40:17.520 --> 0:40:19.480
<v Speaker 2>four weeks plus two weeks or just.

0:40:19.480 --> 0:40:24.480
<v Speaker 1>I don't remember the schedule. Yeah, I don't remember the schedule.

0:40:25.040 --> 0:40:29.360
<v Speaker 2>Well, ask your doctor. Okay, we're not doctors. Stop pressure.

0:40:29.360 --> 0:40:30.920
<v Speaker 1>They'll tell you, like when you go to get your

0:40:30.920 --> 0:40:33.759
<v Speaker 1>little kiddy checkups, they say, you know, come back in

0:40:33.840 --> 0:40:36.160
<v Speaker 1>this month and get your flu shot number one and

0:40:36.160 --> 0:40:37.200
<v Speaker 1>then flu shot number two.

0:40:37.560 --> 0:40:40.200
<v Speaker 2>And so for a while there they there were two

0:40:40.280 --> 0:40:43.000
<v Speaker 2>kinds of flu shots that the CDC recommended. One was

0:40:43.040 --> 0:40:46.480
<v Speaker 2>an actual shot, the flu vaccine that was in a

0:40:46.520 --> 0:40:48.839
<v Speaker 2>shot form, yes, and then there was another one that's

0:40:48.840 --> 0:40:55.439
<v Speaker 2>called live attenuated influenza virus, which came in the form

0:40:55.480 --> 0:40:58.240
<v Speaker 2>of a nasal spray, and that was usually recommended for kids.

0:40:58.320 --> 0:41:00.720
<v Speaker 2>I don't know if it's because kids still like needles

0:41:01.200 --> 0:41:07.160
<v Speaker 2>or what, but the CDC is officially stopped recommending nasal

0:41:08.000 --> 0:41:11.080
<v Speaker 2>flu vaccines. Yeah, don't do those right.

0:41:11.680 --> 0:41:13.560
<v Speaker 1>Well, And when they were doing it, when we say kids,

0:41:13.560 --> 0:41:16.200
<v Speaker 1>you had to be over five because it was a

0:41:16.960 --> 0:41:21.279
<v Speaker 1>like you said, a live a live virus.

0:41:21.120 --> 0:41:23.120
<v Speaker 2>Right, it was a live, weakened virus.

0:41:23.560 --> 0:41:26.359
<v Speaker 1>Yeah, And that's different. Like if you think, all right,

0:41:26.400 --> 0:41:27.960
<v Speaker 1>I'm gonna get a flu shot, so that means I'm

0:41:27.960 --> 0:41:30.680
<v Speaker 1>going to get the flu virus shot into me, and

0:41:30.719 --> 0:41:33.040
<v Speaker 1>so I might feel like I have the flu. That's

0:41:33.120 --> 0:41:35.000
<v Speaker 1>not really the case. It's it's really kind of neat

0:41:35.040 --> 0:41:37.960
<v Speaker 1>how they do it. These these scientists and doctors, like

0:41:38.000 --> 0:41:40.600
<v Speaker 1>you said, track what's going on in the world of

0:41:40.640 --> 0:41:45.160
<v Speaker 1>flu all over the world, and they they sort of

0:41:45.200 --> 0:41:48.560
<v Speaker 1>make up normal. They don't sort of. They very definitely

0:41:48.560 --> 0:41:53.759
<v Speaker 1>make a prediction and say, here's the flu strain specific

0:41:54.000 --> 0:41:56.759
<v Speaker 1>to the United States. Let's say that I think we're

0:41:56.800 --> 0:41:59.120
<v Speaker 1>going to be faced with this year, and they make

0:41:59.160 --> 0:42:03.680
<v Speaker 1>their best side scientific guests possible, and that is, you

0:42:03.719 --> 0:42:07.560
<v Speaker 1>get a not live version of that virus injected into

0:42:07.560 --> 0:42:11.440
<v Speaker 1>your body. Your body sees, hey, foreign invaders here, let

0:42:11.440 --> 0:42:14.560
<v Speaker 1>me produce antibodies. Then if that virus or if the

0:42:14.840 --> 0:42:18.480
<v Speaker 1>real flu knocks on your door later that winter, your

0:42:18.520 --> 0:42:20.719
<v Speaker 1>body says, wait, I've met you before, I know how

0:42:20.719 --> 0:42:21.200
<v Speaker 1>to fight you.

0:42:21.480 --> 0:42:23.160
<v Speaker 2>Yeah, but it's pretty cool.

0:42:23.640 --> 0:42:27.680
<v Speaker 1>And it literally the effectiveness. I looked up this year

0:42:28.360 --> 0:42:30.360
<v Speaker 1>and it's a year to year thing. It's forty to

0:42:30.400 --> 0:42:34.640
<v Speaker 1>sixty percent on this year's strain, and it varies because

0:42:34.680 --> 0:42:38.520
<v Speaker 1>it really just depends on how well those scientists have

0:42:38.640 --> 0:42:39.840
<v Speaker 1>predicted how much they get it.

0:42:39.880 --> 0:42:43.399
<v Speaker 2>Right right, because if they get all three wrong, well

0:42:43.440 --> 0:42:46.520
<v Speaker 2>then you're toast when you encounter the flu that's going

0:42:46.520 --> 0:42:49.719
<v Speaker 2>around that season's right, it's introducing. But even when they

0:42:49.760 --> 0:42:53.080
<v Speaker 2>do get it right, it's kind of baffling that sometimes

0:42:53.120 --> 0:42:57.759
<v Speaker 2>the flu vaccine just doesn't bestow any kind of immunity. Yeah,

0:42:57.840 --> 0:43:02.080
<v Speaker 2>apparently Australia just came out out of a really bad

0:43:02.239 --> 0:43:05.759
<v Speaker 2>epidemic flu season down there, and what didn't cause a

0:43:05.760 --> 0:43:09.080
<v Speaker 2>lot of deaths, but everybody was sick with the flu.

0:43:09.680 --> 0:43:12.120
<v Speaker 2>It was an H three type flu that went around.

0:43:12.320 --> 0:43:15.560
<v Speaker 2>And even though that strain showed up in the vaccine

0:43:15.600 --> 0:43:19.920
<v Speaker 2>that was given out, only like fifteen percent of people

0:43:20.280 --> 0:43:24.080
<v Speaker 2>who got vaccinated and were exposed to the flu were

0:43:24.440 --> 0:43:27.160
<v Speaker 2>immune to it. Like eighty five percent of people who

0:43:27.200 --> 0:43:29.920
<v Speaker 2>got flu vaccines and then encountered the flu still got sick.

0:43:30.200 --> 0:43:33.239
<v Speaker 2>That's a pretty bad track record for a flu vaccine,

0:43:33.280 --> 0:43:36.000
<v Speaker 2>and they're they're just not sure why. And one of

0:43:36.040 --> 0:43:39.480
<v Speaker 2>the theories is so when they make flu vaccines they

0:43:39.520 --> 0:43:43.040
<v Speaker 2>grow them in egg protein typically like hats eggs. That's

0:43:43.080 --> 0:43:45.560
<v Speaker 2>the medium they use actually grow the viruses that they

0:43:45.719 --> 0:43:49.839
<v Speaker 2>then kill. One researcher pointed out that at least one

0:43:49.960 --> 0:43:54.960
<v Speaker 2>kind of flu virus mutates in the presence of egg protein,

0:43:55.440 --> 0:43:58.560
<v Speaker 2>so that the virus that you put in to grow

0:43:58.600 --> 0:44:01.439
<v Speaker 2>in there is different from the one that comes out.

0:44:01.440 --> 0:44:04.600
<v Speaker 2>It's a mutated version, and so maybe that would would

0:44:04.640 --> 0:44:08.360
<v Speaker 2>prevent your body from recognizing the original one that you

0:44:08.400 --> 0:44:11.480
<v Speaker 2>were trying to introduce it to in the vaccine. So interesting,

0:44:11.760 --> 0:44:12.880
<v Speaker 2>it is pretty interesting.

0:44:12.920 --> 0:44:16.080
<v Speaker 1>Well, and they say there's a list of people who

0:44:16.080 --> 0:44:18.320
<v Speaker 1>should not receive the flu shot, and one of the

0:44:18.440 --> 0:44:20.880
<v Speaker 1>one of those qualifications is if you are allergic to

0:44:20.960 --> 0:44:23.760
<v Speaker 1>chicken eggs, then you shouldn't get a flu shot.

0:44:24.040 --> 0:44:26.480
<v Speaker 2>Yeah, there's like a couple of other ways that they

0:44:26.520 --> 0:44:30.239
<v Speaker 2>make flu shots flu vaccines, but that chicken egg is

0:44:30.280 --> 0:44:32.000
<v Speaker 2>the most predominant way to do it.

0:44:32.360 --> 0:44:36.120
<v Speaker 1>Yeah, if you're currently have a fever weight on your

0:44:36.120 --> 0:44:38.799
<v Speaker 1>flu shot under six months, of course, we said you

0:44:38.840 --> 0:44:42.680
<v Speaker 1>cannot if you have had flu shots in the past

0:44:42.680 --> 0:44:45.040
<v Speaker 1>and you had a bad reaction, because like I said,

0:44:45.080 --> 0:44:47.040
<v Speaker 1>it's not going to make you sick, but you might

0:44:47.080 --> 0:44:50.880
<v Speaker 1>feel a little achy or have sore muscles or something,

0:44:51.760 --> 0:44:53.680
<v Speaker 1>but you can't have a bad reaction. And if that's

0:44:53.680 --> 0:44:56.560
<v Speaker 1>the case, then maybe flu shots aren't for you, right.

0:44:56.600 --> 0:44:59.120
<v Speaker 2>And if you're an anti vaxxer, then you probably are

0:44:59.320 --> 0:45:03.680
<v Speaker 2>decided that flu shots aren't for you, correct, which we

0:45:03.719 --> 0:45:05.359
<v Speaker 2>will never do an episode on that.

0:45:05.800 --> 0:45:09.000
<v Speaker 1>On vaccinations, right. Oh, you don't think.

0:45:08.840 --> 0:45:12.880
<v Speaker 2>So, I don't know, man. So the idea that a

0:45:12.920 --> 0:45:17.440
<v Speaker 2>flu vaccine can, you know, check all the boxes but

0:45:17.560 --> 0:45:21.000
<v Speaker 2>still just be wrong, wrong, wrong, or not confer immunity

0:45:21.920 --> 0:45:25.680
<v Speaker 2>has some people looking for a universal vaccine or one

0:45:25.719 --> 0:45:29.600
<v Speaker 2>that lasts way longer than just a year. What they're

0:45:29.640 --> 0:45:33.239
<v Speaker 2>targeting is, so when you get a normal vaccine, that

0:45:33.440 --> 0:45:42.000
<v Speaker 2>vaccine is based on that HA protein, the hema gluten. Yeah,

0:45:42.120 --> 0:45:46.359
<v Speaker 2>and that's the most quickly evolving part of any flu virus. Right.

0:45:46.760 --> 0:45:48.920
<v Speaker 2>So they're saying, well, let's look at other parts of

0:45:48.960 --> 0:45:51.560
<v Speaker 2>the flu virus that don't evolve nearly as quickly and

0:45:51.680 --> 0:45:55.040
<v Speaker 2>target that. And some of those parts are even basically

0:45:55.160 --> 0:45:57.960
<v Speaker 2>universal among all flu viruses. So if you can find

0:45:58.160 --> 0:46:01.080
<v Speaker 2>if you can create a vaccine based on a stable

0:46:01.160 --> 0:46:03.360
<v Speaker 2>part of a flu virus that's a part of every

0:46:03.400 --> 0:46:09.479
<v Speaker 2>flu virus. One vaccine could confer ideally lifelong immunity from

0:46:09.600 --> 0:46:13.200
<v Speaker 2>all influenza for anybody who takes the vaccine.

0:46:13.080 --> 0:46:15.920
<v Speaker 1>One vaccine to cure them all exactly. Wow.

0:46:16.520 --> 0:46:19.919
<v Speaker 2>Yeah, so you got anything else?

0:46:20.440 --> 0:46:22.560
<v Speaker 1>No? I mean, I guess we're not going to cover

0:46:22.600 --> 0:46:23.520
<v Speaker 1>the boogie Wigi Flu.

0:46:24.920 --> 0:46:26.480
<v Speaker 2>I thought that was boogie woogy fever.

0:46:27.000 --> 0:46:29.200
<v Speaker 1>No, it's the rock and pneumonia the boogie wigy flu.

0:46:29.320 --> 0:46:33.000
<v Speaker 2>Oh that's nice. What's that from? Is that an Atlanta

0:46:33.080 --> 0:46:34.000
<v Speaker 2>Rhythm Section song?

0:46:34.760 --> 0:46:36.040
<v Speaker 1>No, they're better than that.

0:46:37.640 --> 0:46:43.160
<v Speaker 2>Okay, Uh, well, since I said Atlanta Rhythm Section everybody,

0:46:44.040 --> 0:46:46.120
<v Speaker 2>that means it's time for a listener mail.

0:46:48.840 --> 0:46:53.600
<v Speaker 1>Uh. Yeah. This is a Simpson's Overlooked overlook Simpsons bet

0:46:53.640 --> 0:46:56.880
<v Speaker 1>from us. And this is not one of those We

0:46:57.000 --> 0:46:58.839
<v Speaker 1>got plenty of things where people like, hell, could you

0:46:58.880 --> 0:47:03.000
<v Speaker 1>not have mentioned this quote or this episode? But the

0:47:03.040 --> 0:47:06.759
<v Speaker 1>response was good. Then people weren't necessarily poopooing it.

0:47:07.560 --> 0:47:10.040
<v Speaker 2>No. And also I want to say thank you to

0:47:10.120 --> 0:47:13.600
<v Speaker 2>everybody who wrote in to just say congratulations or to

0:47:13.680 --> 0:47:16.359
<v Speaker 2>thank us. That was all. Every single one of those

0:47:16.360 --> 0:47:19.040
<v Speaker 2>emails or tweets or posts were all well received. So

0:47:19.080 --> 0:47:20.800
<v Speaker 2>thanks for those guys.

0:47:20.320 --> 0:47:23.839
<v Speaker 1>Totally, But this is something we failed to mention, which

0:47:24.160 --> 0:47:27.279
<v Speaker 1>definitely deserves its own email. And this is from rich

0:47:28.400 --> 0:47:31.759
<v Speaker 1>our Man on Cape cod As. He says, Hey, guys,

0:47:31.880 --> 0:47:34.160
<v Speaker 1>was listening to The Simpsons two parter. Enjoyed it very much.

0:47:34.560 --> 0:47:37.000
<v Speaker 1>You explained how an episode came to be, from conception

0:47:37.760 --> 0:47:40.240
<v Speaker 1>to animation, etc. And you paid respect to each portion.

0:47:40.880 --> 0:47:42.719
<v Speaker 1>But then you slide it off one of the most

0:47:42.719 --> 0:47:44.799
<v Speaker 1>important men in the franchise, you just said, and then

0:47:44.840 --> 0:47:47.800
<v Speaker 1>they slapped Danny Elfman's score on it and it's done well.

0:47:48.920 --> 0:47:52.000
<v Speaker 1>Is any true Simpsons officionado would know? Danny Elfman has

0:47:52.040 --> 0:47:55.280
<v Speaker 1>never once written a score to The Simpsons. He wrote,

0:47:55.520 --> 0:47:59.759
<v Speaker 1>as we know, just the title or the theme song.

0:48:00.400 --> 0:48:03.920
<v Speaker 1>So he says that job fell to the immensely talented

0:48:04.200 --> 0:48:09.520
<v Speaker 1>and recently terminated via email, Alf Clawson. For twenty seven years,

0:48:09.560 --> 0:48:13.080
<v Speaker 1>every score, every queue, every song was composed, orchestrated and

0:48:13.080 --> 0:48:16.680
<v Speaker 1>conducted by Clawson and his live orchestra. He's won two

0:48:16.719 --> 0:48:20.000
<v Speaker 1>Emmys and seven Annie Awards for his work. The reason

0:48:20.080 --> 0:48:23.160
<v Speaker 1>this is such a painful sight it was because this

0:48:23.280 --> 0:48:26.600
<v Speaker 1>omission has been happening for years. Clawson has worked insane

0:48:26.600 --> 0:48:29.680
<v Speaker 1>hours writing music for a live orchestra to accompany an

0:48:29.719 --> 0:48:33.440
<v Speaker 1>animated show. He's always played second fiddle. Nailed it, he

0:48:33.560 --> 0:48:36.640
<v Speaker 1>said to all those who think Elfman is any part

0:48:36.680 --> 0:48:39.040
<v Speaker 1>of the show, after he pinned the main title. In fact,

0:48:39.040 --> 0:48:42.200
<v Speaker 1>the main title theme song We All Know and Love

0:48:42.280 --> 0:48:46.399
<v Speaker 1>is actually Clawson's re orchestration of Elfman's theme that took

0:48:46.440 --> 0:48:51.840
<v Speaker 1>place mid season three with a lusher, more crisp orchestration. Wow,

0:48:51.920 --> 0:48:54.400
<v Speaker 1>I bet you anything, Rich plays the obo.

0:48:54.360 --> 0:48:56.840
<v Speaker 2>Alf Clawson. I'm so sorry.

0:48:56.680 --> 0:48:58.600
<v Speaker 1>I know, he said. I myer your podcast for being

0:48:58.719 --> 0:49:01.960
<v Speaker 1>light to information that has been stuck lurking in the shadows.

0:49:01.960 --> 0:49:04.680
<v Speaker 1>You always make sure a credit is given to those

0:49:05.040 --> 0:49:07.879
<v Speaker 1>who sometimes went their entire lives without getting the nod

0:49:07.920 --> 0:49:08.400
<v Speaker 1>they deserve.

0:49:08.560 --> 0:49:10.920
<v Speaker 2>Well, this guy's really turning the knife in our back,

0:49:10.960 --> 0:49:11.400
<v Speaker 2>saysn't he.

0:49:12.239 --> 0:49:15.439
<v Speaker 1>And I feel you, oh Clawson, that respect. So Alf

0:49:15.520 --> 0:49:18.560
<v Speaker 1>clawsan for real. And then it was a bit of

0:49:18.560 --> 0:49:20.160
<v Speaker 1>a longer email. He told the story of how he

0:49:20.239 --> 0:49:22.960
<v Speaker 1>was recently fired by email, which is not cool.

0:49:23.160 --> 0:49:28.080
<v Speaker 2>No, it's definitely not Yeah. So twenty seven years yeah,

0:49:28.360 --> 0:49:29.680
<v Speaker 2>of dedicated work.

0:49:29.920 --> 0:49:32.640
<v Speaker 1>No man, not cool, guys, So that is a rich

0:49:32.680 --> 0:49:34.080
<v Speaker 1>our Man on Cape cod.

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<v Speaker 2>Well, thanks a lot, Rich appreciate that that was one

0:49:36.719 --> 0:49:38.279
<v Speaker 2>of the better emails I've heard in a while.

0:49:38.320 --> 0:49:38.720
<v Speaker 1>I agreed.

0:49:39.600 --> 0:49:41.680
<v Speaker 2>If you want to try and top Rich, let's see

0:49:41.680 --> 0:49:44.280
<v Speaker 2>what you got. You send us an email, stuff podcast

0:49:44.320 --> 0:49:47.359
<v Speaker 2>at houstuffworks dot com and join us at our home

0:49:47.440 --> 0:49:52.480
<v Speaker 2>on the web. Stuff you Should Know dot Com.

0:49:52.600 --> 0:49:55.480
<v Speaker 1>Stuff you Should Know is a production of iHeartRadio. For

0:49:55.560 --> 0:49:59.719
<v Speaker 1>more podcasts my heart Radio, visit the iHeartRadio app Apple Podcasts,

0:50:00.000 --> 0:50:01.680
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