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Speaker 1: Chris Colosso is our guest. He is my new, relatively

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Speaker 1: new allergist. He's been my wife's salergist for five years.

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Speaker 1: She's had amazing results, and I wanted him to come

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Speaker 1: on with it being when we started. He said, look,

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Speaker 1: we're about to start pollen season, so you are going

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Speaker 1: to have a flare. Let's talk about what we're going

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Speaker 1: to do. And I said, that's a perfect time to

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Speaker 1: have you on the show. I like the fact that

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Speaker 1: he very patiently answers all my many questions and you

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Speaker 1: can imagine what it's like to be my doctor. Mary

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Speaker 1: Telly Boden told me one time that I shouldn't ask

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Speaker 1: so many questions. It's distracting, and I just laughed and

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Speaker 1: I said, Mary, tell you don't know. That's just me.

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Speaker 1: Every doctor that's treated me will tell you that, and

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Speaker 1: they all know. They all hate it, but they all know. Anyway,

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Speaker 1: he patiently answered my questions and with a lifetime of sneezing,

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Speaker 1: runny eyes congestion, I wanted him to share with you

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Speaker 1: his experience because he kind of geeks out on this stuff,

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Speaker 1: and I'm glad to know that somebody does. Chris Colosso

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Speaker 1: is our guest. So doctor Colosso you see this pollen

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Speaker 1: that's coming down, and you were talking about you and

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Speaker 1: I were talking about, uh, this being the season where

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Speaker 1: it really causes people to flare. What are the big

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Speaker 1: allergies and antigens that that people would know the street

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Speaker 1: name of that make this season so bad?

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Speaker 2: So you know this this season, everybody, you know, all

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Speaker 2: that yellow stuff you see coding the oak pollen is

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Speaker 2: going to you know, is going to go through the roof,

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Speaker 2: I mean every street and you don't and people are like, oh,

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Speaker 2: should I take down my oak tree in my arm

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Speaker 2: And I'm like, no, it's going to make no difference

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Speaker 2: because the pollen level is going to be thick in

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Speaker 2: the air and you can and you can you know,

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Speaker 2: on our website we have you know, there's a link

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Speaker 2: to the City of Houston pollen counter and you know

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Speaker 2: it'll get up to the thousands and thousands of pollen

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Speaker 2: count in the air. And the biggest you know trees

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Speaker 2: over here that we have trouble with is oh pecan

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Speaker 2: Ash and you know, and they start off at you know,

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Speaker 2: different times, and so ash reason to be a little

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Speaker 2: bit early, okay, is through the major of springtime and

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Speaker 2: then you know, pe con tends to be a little

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Speaker 2: bit later on this season. But besides that, you know,

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Speaker 2: the hedges and all those things that are pollinating. Springtime

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Speaker 2: tends to be the worst for more for most patients.

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Speaker 2: And we have patients who are you know, typically they'll

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Speaker 2: have allergy to uh to springtime trees, but they also

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Speaker 2: show a dust light allergy and so you know, and

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Speaker 2: that's why sometimes when I explain to patients, I was like,

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Speaker 2: they're like, but dost say, I don't feel anything with

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Speaker 2: the dust smiles, And it's like, no, you probably do,

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Speaker 2: but it's just that you have this baseline because the

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Speaker 2: dust mil stuff is there year around, right, so you

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Speaker 2: have symptoms throughout the year, and so you just sort

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Speaker 2: of if you will, you're sort of used to being miserable,

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Speaker 2: and then you have this and then a long come

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Speaker 2: spring and just adds on to that. And so part

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Speaker 2: of controlling allergy is trying to reset that baseline. And

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Speaker 2: so as I did with Michael, I stressed with him

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Speaker 2: that you know, make sure that you.

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Speaker 3: Do dust my covers.

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Speaker 2: Now, dust my covers are not going to you know,

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Speaker 2: one hundred percent eliminate dust might but it's going to

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Speaker 2: drop the load. So it's going to drop that load.

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Speaker 2: And so now that baseline is set a little bit

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Speaker 2: lower so that when that spring pollen comes hits you,

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Speaker 2: you're not already at the super high level of you know,

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Speaker 2: being miserable. And so that's why you know, seeing a

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Speaker 2: specialist you know, can help you understand and sort of

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Speaker 2: target the allergy from you know, not only just medicines,

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Speaker 2: but also avoidance measures and other treatment modalities, and that's

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Speaker 2: that will just help you feel better overall.

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Speaker 1: Chris cool he is an allergist and his clinic is

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Speaker 1: Advanced Allergy and Asthma Center. Go ahead, that was just.

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Speaker 2: Oh, Michael, I just want to you know, we are

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Speaker 2: Advanced Asthma Analogy Center, but it's you know, it's.

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Speaker 1: Semantics allergies before let me ask you.

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Speaker 3: This advance asthma analergy.

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Speaker 1: Okay, let me ask you this. So this treatment to

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Speaker 1: make your body not you know through these like one

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Speaker 1: of the forms of treatment is the shots. And that's

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Speaker 1: what I've started doing. Is what's my wife has gotten

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Speaker 1: encourage with. If our body no longer reacts to the pollen,

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Speaker 1: when when is there any downside to that? I mean,

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Speaker 1: did our body react to try to protect us?

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Speaker 2: No, they because remember that arm of the immune system,

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Speaker 2: your body started reacting to the pollen, not.

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Speaker 3: Because it was truly protecting you.

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Speaker 2: That arm of the immune system was designed to fight parasites.

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Speaker 2: But when you don't have much parasite exposure, you don't

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Speaker 2: have you know, worms and those kinds of things, it

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Speaker 2: had nothing to do, and so it was not it

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Speaker 2: wasn't reacting in the first place to protect you. It's

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Speaker 2: sort of started reacting just because it wasn't busy enough

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Speaker 2: to do that, and so that comes. You know, there's

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Speaker 2: an interesting thing known as the hygiene hypothesis of why

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Speaker 2: allergies go. And it's very interesting with something you said.

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Speaker 2: So your wife, like me, grew up in India, and

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Speaker 2: it's very interesting. Allergy tends to be a disease of

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Speaker 2: the advanced world.

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Speaker 3: In the.

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Speaker 2: In the Third world, they tend to have much less allergy.

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Speaker 2: And the thinking is a lot of that has to

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Speaker 2: do because we get exposed. You know, people who grew

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Speaker 2: up in the Third world or even in farming communities,

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Speaker 2: tend to be exposed to a higher level of endotoxin.

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Speaker 2: An endotoxin is just dirt or you know, for lack

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Speaker 2: of a better word, and sometimes what you find in

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Speaker 2: manure and that kind of stuff outside, and when that

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Speaker 2: part of the immune system is stimulated, it tends to

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Speaker 2: suppress the allergic response. And so remember how you said that,

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Speaker 2: you know, when your wife first came, she had never

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Speaker 2: had trouble with allergy, right, And that's what we see

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Speaker 2: over here too, Like I never had allergy for twenty years,

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Speaker 2: and it's only being in, you know, in sort of

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Speaker 2: a cleaner environment that that arm of the immune system

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Speaker 2: starts reacting, whereas in you know, in a dirty environment

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Speaker 2: if you will, or just being exposed to more dirt,

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Speaker 2: it keeps the allergy part of it under control.

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Speaker 1: So it's almost if you don't use it, you lose it,

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Speaker 1: or a weak muscle. Because the developed world, and especially

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Speaker 1: the United States, is so hygienic, body does not develop

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Speaker 1: the ability to fight off these things, and so when

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Speaker 1: they hit us, it hits us harder as opposed to

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Speaker 1: growing up on the rough streets of the third world

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Speaker 1: sort of thing, and your body has has developed an

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Speaker 1: immunity to that. It's a fascinating hypothesis, I'm absolutely fascinating.

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Speaker 2: Right, And that's that's what's considered the hygiene hypothesis and

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Speaker 2: so and it's it's not so much that the body

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Speaker 2: didn't develop the immunity, but it's that the infection keeps

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Speaker 2: this arm of the immune system, the allergy part, not reacting.

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Speaker 2: And once you take away you know, a lot of

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Speaker 2: those the infection.

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Speaker 3: Or you.

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Speaker 2: Know, and they talk about just being outside and playing

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Speaker 2: in the dirt and those kind things help decrease allergy.

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Speaker 1: Let's talk about that, because you and I have had

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Speaker 1: that conversation. I think it's important, Doctor Chris Colosso advanced

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Speaker 1: asthma and allergy coming.

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Speaker 2: Out today to the Colonial House apartments and receive.

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Speaker 1: A free and we're recorded. Doctor Chris Colosso has been

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Speaker 1: my wife's allargist for five years. She's had phenomenal results.

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Speaker 1: I have recently started with him and he answered all

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Speaker 1: my questions and he literally sat down. He owns the clinic,

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Speaker 1: so it's not like being part of one of the

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Speaker 1: big hospital systems where you got to churn people so fast.

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Speaker 1: But he in much the same way that I have

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Speaker 1: conversations with Mohit Kara and Jim Munks and other doctors

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Speaker 1: that are just you know, they geek out over their

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Speaker 1: area of expertise, and I love that and I asked

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Speaker 1: him to share some of that with you, doctor Colosso

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Speaker 1: let's talk about what people if someone doesn't have Medicare,

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Speaker 1: doesn't have a healthcare program, doesn't is not able to

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Speaker 1: come and see you, what are some basic things that

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Speaker 1: people can do to get through pollen season when they're

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Speaker 1: having difficulty.

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Speaker 2: So you know, the best thing to do is to

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Speaker 2: try and avoid it. So it's so sinus instance. Now

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Speaker 2: that's something simple and.

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Speaker 3: You know, very easy to do.

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Speaker 2: And so if you do go take the dog out

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Speaker 2: for a walk. As soon as you come back, do

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Speaker 2: a science trench. That's you know, if you're going to

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Speaker 2: blow all your leaves out, wear a mask because the

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Speaker 2: higher level of pollen that you that you expose yourself to,

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Speaker 2: the more chance that you're going to have were symptoms.

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Speaker 2: The other the one of the other things you can

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Speaker 2: do is you know, if you know that you know

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Speaker 2: dust may be a trigger of those kind of things,

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Speaker 2: then you know, keep the humidity low because the lower

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Speaker 2: the humidity in the house, the less dust my populations,

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Speaker 2: uh you know survive or you know you're decreased the

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Speaker 2: dust my population, and then you know there's medicines and

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Speaker 2: so you know, using the medicines during you know, during

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Speaker 2: pollen season and now since that most of these things

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Speaker 2: are over the counter, So using an antihistamine and using

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Speaker 2: a nose pray will help control the symptoms so you're

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Speaker 2: not as miserable. So in in in those you know,

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Speaker 2: and that's in that way you can try and you know,

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Speaker 2: sort of keep the symptoms controlled. But this would not

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Speaker 2: be the time to you know, when you know, when

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Speaker 2: you see you know, these.

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Speaker 3: Guys blowing all the pollen all around.

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Speaker 2: To walk through that pollen cloud, you're going to be miserable,

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Speaker 2: and so you know, trying to sort of avoid it.

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Speaker 2: Using and using the medications that are over the counter

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Speaker 2: judiciously will help you alive.

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Speaker 1: You seem to prefer to start with zyrtech and if

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Speaker 1: somebody can handle it, use that and if they can't,

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Speaker 1: move on. Why is that is that the best over

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Speaker 1: the counter drug?

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Speaker 2: I feel Zyrtec tends to work a little bit better

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Speaker 2: than some of the antihistamines, but you know, it has

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Speaker 2: a thing that it can cause drowsiness, and so five

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Speaker 2: percentral maybe a little bit less of the people who

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Speaker 2: take it, you know, will say it makes them sleepy,

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Speaker 2: and so there's other there's other anti hist meines over

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Speaker 2: the counter. Allegra does not you know, across the blood

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Speaker 2: brain barrier, and so you know, in pilots or someone

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Speaker 2: with a commercial drug driver's license, you know, i'd say, hey,

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Speaker 2: you need to use Allegra as your antihistamy because we

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Speaker 2: can't have any of those you know, you can't be

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Speaker 2: drowsy and those kind of things.

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Speaker 1: But you don't start with Allegra because you think Zyrtech,

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Speaker 1: if the person can handle it, is more effective.

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Speaker 2: Typically is a little bit it is a little bit better.

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Speaker 2: But you know, everything every and you know, I run

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Speaker 2: into this all the time where patients will tell me, no, doctor,

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Speaker 2: see Allegra works better for me or whatever. Everyone's immune

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Speaker 2: system is sort of a little different, and so you know,

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Speaker 2: sometimes patients tend to prefer, you know, which medicine works best.

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Speaker 3: For them without the side effects. But I feel Zyrtech

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Speaker 3: is a really good anti history to help control.

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Speaker 1: And then after that down the list you would go Allegra.

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Speaker 3: And then what I go, yeah, mine is Clariton.

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Speaker 2: After that, I don't like chronic use of first generation antihistmines,

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Speaker 2: because all of those tend to cross the blood brain

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Speaker 2: barrier and they all tend to make you drowsing. And

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Speaker 2: then there was you know, some studies out from a

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Speaker 2: while ago with you know, with New England General Medicine.

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Speaker 2: They talked about you know, long term use of first

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Speaker 2: generation antihistamines maybe and you know, maybe associated with dementia

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Speaker 2: later on. And so I try to avoid using chronic

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Speaker 2: use of first generation anti history means.

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Speaker 1: And the first generation antihistamines are Zerotech, Allegra and Clard no.

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Speaker 2: No, no, sorry, the first generation answer his means a benadryl,

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Speaker 2: oh okay. And then there's some chlorophane from penmen in love.

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Speaker 3: Those a little bit hard to find, okay.

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Speaker 1: So just to wrap that up in case people weren't

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Speaker 1: paying close attention, You're not in favor of using benadryl

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Speaker 1: long term because that was an early drug and you

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Speaker 1: think there may potentially be some problems with.

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Speaker 2: That, right and and everyone, you know, And my thing

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Speaker 2: is I explained to patients that the way these anti histamines,

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Speaker 2: they tend to block or trap the history receptor in

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Speaker 2: the enactive form, so conbined histamy benadrol.

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Speaker 3: Will do that for four to six hours, and then

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Speaker 3: it falls off the receptor, so the receptors.

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Speaker 2: Open again, and you have the bad side effect that

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Speaker 2: it can put you to sleep. So why would you

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Speaker 2: do that if there's better, if there's you know, the

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Speaker 2: most of the second generation antist means like zootech and

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Speaker 2: Clarton a Leger and those kind of things last twenty

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Speaker 2: four hours, and they are much less They cause much

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Speaker 2: less growsiness than the first generations. So that's why I

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Speaker 2: don't like the first generation as instruments.

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Speaker 1: It's very interesting the over the counter of zyrtech, I think,

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Speaker 1: I mean you talked about it tends to mask problems

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Speaker 1: for people who who for those who end up with

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Speaker 1: very chronic conditions. But I would be interested to know,

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Speaker 1: and I don't know if you have any sense what

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Speaker 1: percentage of the population is on one of those latter

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Speaker 1: generation zerotech Allegra Cleraton on a relatively regular basis, which

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Speaker 1: by the way, he put me on zertech and I

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Speaker 1: do fine with it. I wonder what percentage of the

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Speaker 1: population is on that, because I would assume that makes

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Speaker 1: a big difference, at least at least to giving people

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Speaker 1: some comfort, some relief no.

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Speaker 2: I think a lot of people and then they say

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Speaker 2: maybe sixteen hundred million people have allergy. But once those

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Speaker 2: things go over the counter, then you know, I guess

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Speaker 2: at some point they used to be able to track it,

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Speaker 2: but now you don't. But you know, given how well

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Speaker 2: those you know, the drugs have done. And you know,

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Speaker 2: I see many people who are those antihistamines Y're around

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Speaker 2: all the time.

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Speaker 1: Do you see a problem with that?

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Speaker 2: There's pretty good data out and right now, I sometimes

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Speaker 2: you know, if you like I told you that, if

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Speaker 2: zerotech doesn't knock you out, then then it's fine. But

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Speaker 2: you know, I try to make sure that you use

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Speaker 2: drugs that you know don't affect uh, you know, slow

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Speaker 2: you down and those kinds of things.

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Speaker 1: You know, well, I don't know, I told you, but

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Speaker 1: none that the is she She says that it makes

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Speaker 1: her drowsy, which it does, but she didn't tell that

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Speaker 1: it makes her a little angry. And the reason we

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Speaker 1: knew that, the boys and I is because she's never angry.

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Speaker 1: She is the sweetest person one hundred percent of the time.

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Speaker 1: People don't believe she can be that nice. And she

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Speaker 1: started on that and about the third time she took it.

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Speaker 1: She said, Hey, I'm going to take my zirtech and

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Speaker 1: go to bed. I'm just warning you in case I'm grumpy.

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Speaker 1: I'm not mad at you. It has that effect, but

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Speaker 1: please tell me if I do that. And so she

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Speaker 1: started keeping notes herself and said okay. That's when she

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Speaker 1: came to you and said, okay, I need to switch

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Speaker 1: to something else. Chris Colosso is our guest advanced asthma

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Speaker 1: and allergy. If you would like to go and see him,

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Speaker 1: I would be happy to connect you. Otherwise, we're talking

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Speaker 1: in the middle of pollen season. At least for those

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Speaker 1: of you who don't know. I'm in Houston and in

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Speaker 1: Southeast Texas where we are right about now. Most everybody

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Speaker 1: you talk to is sneezing, nodding, stuffy head, the whole,

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Speaker 1: the whole deal. And that's why I wanted to talk

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Speaker 1: to him today. We'll go to your conversation.

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Speaker 3: Man's the term anal intercourse on your.

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Speaker 1: Program, Michael, if it's relevant to this story for journalistic purposes.

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Speaker 1: Chris Colosso is my wife's allergist, has been for five

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Speaker 1: years to great result. She finally dragged me to see

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Speaker 1: him a month or so ago and I've gone through

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Speaker 1: my tests, and I really like the fact that he

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Speaker 1: takes the time to answer all my many questions. I

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Speaker 1: don't believe doctors are gods. I think that doctors are

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Speaker 1: like everyone else, doing the best they can. I love

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Speaker 1: the fact that he quotes studies, which means he's keeping

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Speaker 1: up with, uh, you know, the developments in his field.

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Speaker 1: I think a lot some doctors, not a lot, a

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Speaker 1: few doctors, they get kind of they get stuck in

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Speaker 1: the in the ways of doctor Spock's, you know, book

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Speaker 1: on newborns, and they don't keep up with new trends

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Speaker 1: and new developments and new data that's coming out, and

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Speaker 1: he does. And I really like that, Doctor Colosso let's

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Speaker 1: talk about You told me something very interesting. I had

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Speaker 1: had the test done on the allergy test that a

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Speaker 1: lot of people have had earlier in life, where they

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Speaker 1: do the pin pricks and then you see what flares,

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Speaker 1: and y'all have changed the dosage you use for that

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Speaker 1: because people were literally dying through that, and now you

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Speaker 1: have a two pronged approach. Can you explain that?

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Speaker 3: So that's true?

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Speaker 2: So in adults and so for allergy testing, my cutoff

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Speaker 2: is sixteen and above and so in you know, a

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Speaker 2: long time ago, maybe twenty thirty years they would ask

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Speaker 2: the patient, Hey, how's your allergy, and you know, usually

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Speaker 2: it's guys, and they'd be like, Eh, it's not that

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Speaker 2: bad dog. And so they would go straight to an

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Speaker 2: intradomal test, where you would inject the allergen into the

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Speaker 2: surface of the skin, and as a result of that,

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Speaker 2: they gave some people anaphalaxis, which is like a full

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Speaker 2: body allergic reaction, almost kill them.

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Speaker 3: And so.

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Speaker 2: Then about you know, maybe twenty five years ago, they said, oh,

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Speaker 2: you can't you know, kill the patient to make the diagnosis.

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Speaker 2: That's not good medicine. And so they change it and

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Speaker 2: they said, you always do a scratch test, so literally

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Speaker 2: we just barely scratch the skin with the extract, and

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Speaker 2: you know, as in your case, Michael, there were several

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Speaker 2: of the things that had strong positive reactions. So you

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Speaker 2: could imagine that if I went, you know, if I

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Speaker 2: didn't do that and I went straight to the needle test,

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Speaker 2: where we'd inject a little bit into the surface of

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Speaker 2: the skin, we could have caused your whole arm to

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Speaker 2: swell up and you know, shortness of breath and all

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Speaker 2: those things, you.

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Speaker 3: Know, which is like a full body allergic reaction.

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Speaker 2: And so that's why we now, I don't you know,

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Speaker 2: it's it's kind of hard. But with some of the

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Speaker 2: old aurgies. When I first started, you know, in training,

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Speaker 2: I mean they would do needle tests, that means the

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Speaker 2: introdom test, even on little kids, I don't typically we

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Speaker 2: usually do scratch testing, and whatever's positive is positive. In adults,

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Speaker 2: we do the needle test because it'll pick up some

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Speaker 2: minor allergens that you don't see on scratch testing. And

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Speaker 2: so sometimes that way, if the patient you know, decides

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Speaker 2: to do allergen and in a therapy allergy shots, we

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Speaker 2: would put not only would reacted on the first step,

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Speaker 2: but also on the second step. And so you know,

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Speaker 2: that's that's how we try to do both so as

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Speaker 2: to not and do it in a stepwise fashion, because

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Speaker 2: if someone has a big reaction on scratch testing, I

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Speaker 2: would not do the second.

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Speaker 3: Part that day.

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Speaker 2: Because when I first started, you know a lot of

365
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Speaker 2: patients would be like, now to see do it. I'll

366
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Speaker 2: be fine, and we go ahead and start three or

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Speaker 2: four and then they're like, oh, my throat feels weird,

368
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Speaker 2: or I have difficulties swallowing or you know those kinds

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Speaker 2: of things, and when we have to stop and you know,

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Speaker 2: treat the reaction. And so now we just split it up,

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Speaker 2: and someone has a big reaction with just scratch testing,

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Speaker 2: we don't do the second part of the allergy testing

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Speaker 2: on that day. But then I used usually use both

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Speaker 2: of the testings data to decide the best way forward.

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Speaker 1: So with that data, I know you personally do the

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Speaker 1: recipe for the shots. How does that work you personally?

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Speaker 1: What do you then do?

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Speaker 2: So then I will write a recipe and say, hey,

379
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Speaker 2: so let's just make up something. Let's just say for

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Speaker 2: for for the sake of argument someone and there's.

381
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Speaker 1: You can use case.

382
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Speaker 3: Let's say you're allergic. It's not help let's see, yeah

383
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Speaker 3: that's true.

384
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Speaker 2: So let's say you're allergic to dust mites and oak

385
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Speaker 2: and and you know some of the moles or whatever,

386
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Speaker 2: and so then you physically, So I would write out

387
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Speaker 2: a recipe of how much of these different extracts that

388
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Speaker 2: I would put into a vial to make up, you know,

389
00:21:03,240 --> 00:21:06,640
Speaker 2: make a vial so that would have those extracts in there,

390
00:21:07,480 --> 00:21:11,679
Speaker 2: and then we would dilute down that vial one hundred

391
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Speaker 2: thousand fold and then physically you would you know, if

392
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Speaker 2: we were doing alergie shots, you would come and there's

393
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Speaker 2: two ways, and we talked about this. There's different ways

394
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Speaker 2: you can build up, but let's just do this slow

395
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Speaker 2: normal way. Patients would come and they get this most

396
00:21:28,680 --> 00:21:32,840
Speaker 2: shot first. And each time you get a shot, it's

397
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Speaker 2: a higher dose or a higher concentration, And so you're

398
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Speaker 2: moving up and the goal is to get to the

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Speaker 2: highest dose that the patient can tolerate without having any

400
00:21:45,200 --> 00:21:48,240
Speaker 2: systemic symptoms. And one of the other things I'll bring

401
00:21:48,280 --> 00:21:51,320
Speaker 2: out is, you know why you get shots at a

402
00:21:51,359 --> 00:21:55,200
Speaker 2: doctor's office, but the goal is to try and keep

403
00:21:55,440 --> 00:21:58,000
Speaker 2: you know, so each time, So you start off at

404
00:21:58,000 --> 00:22:01,200
Speaker 2: one as two hundred thousand dilution. Once you finish that

405
00:22:01,640 --> 00:22:04,080
Speaker 2: one hundred thousand delution will take about four weeks, you

406
00:22:04,119 --> 00:22:07,080
Speaker 2: go to the one is to ten thousand, you finish that,

407
00:22:07,160 --> 00:22:08,960
Speaker 2: you go one is to one thousand, then you go

408
00:22:09,040 --> 00:22:11,000
Speaker 2: one is to one hundred, you one is to ten.

409
00:22:11,440 --> 00:22:13,920
Speaker 2: So each time when you're moving up in shots, you're

410
00:22:13,920 --> 00:22:17,200
Speaker 2: getting a tenfold increase in the concentration of the shot.

411
00:22:18,480 --> 00:22:22,000
Speaker 2: And what that is doing is slowly training the immune

412
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Speaker 2: system to not react to and most of our patients

413
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Speaker 2: tend to, you know, over the period of the shots,

414
00:22:28,880 --> 00:22:32,960
Speaker 2: tend to tolerate the full strength bial, which is you know,

415
00:22:33,520 --> 00:22:36,359
Speaker 2: and you'll see where the vial is yellow because that's

416
00:22:36,440 --> 00:22:40,280
Speaker 2: the color of pollen and so it's fairly thick and

417
00:22:40,440 --> 00:22:42,800
Speaker 2: have a lot of the pollm extract in there. That

418
00:22:42,880 --> 00:22:45,640
Speaker 2: it's only in the higher doses of the thing, that

419
00:22:46,359 --> 00:22:50,040
Speaker 2: of the vials that you notice that you start seeing,

420
00:22:51,280 --> 00:22:55,360
Speaker 2: you know, clinical benefit. And that's why I warn you

421
00:22:55,400 --> 00:22:58,040
Speaker 2: that this is too late to help you for spring,

422
00:22:58,400 --> 00:23:02,960
Speaker 2: because spring is from bringing and you know, the initial

423
00:23:03,000 --> 00:23:05,600
Speaker 2: part of the shots is not going to help much

424
00:23:05,600 --> 00:23:08,480
Speaker 2: with that. Because again, this is a process of changing

425
00:23:08,560 --> 00:23:11,120
Speaker 2: the immune system and it you know, took fifty four

426
00:23:11,200 --> 00:23:13,840
Speaker 2: years for your immune system to get this way. It

427
00:23:13,880 --> 00:23:16,560
Speaker 2: would be unreasonable to you know, think that it would

428
00:23:16,640 --> 00:23:20,840
Speaker 2: change in you know, a few weeks. And so you know,

429
00:23:21,080 --> 00:23:25,600
Speaker 2: alergenemmut therapy is a process and and and that's why

430
00:23:25,720 --> 00:23:29,800
Speaker 2: you do it. And there's always a risk and so

431
00:23:30,040 --> 00:23:32,600
Speaker 2: there's a very small risk it happens maybe one in

432
00:23:32,640 --> 00:23:35,720
Speaker 2: five hundred thousand shots, but you could because we're giving

433
00:23:35,720 --> 00:23:38,320
Speaker 2: you stuff you're allergic to, and so there's a rare

434
00:23:38,400 --> 00:23:40,600
Speaker 2: risk that you could have an allergic reaction. And that's

435
00:23:40,600 --> 00:23:43,639
Speaker 2: why you know, with all our patients, we you know,

436
00:23:43,720 --> 00:23:47,840
Speaker 2: have them have their own either injectable or now nasal

437
00:23:47,880 --> 00:23:51,560
Speaker 2: at the effort. So that's what the guidelines are. And

438
00:23:51,600 --> 00:23:53,240
Speaker 2: they usually get their shot and they have to sit

439
00:23:53,280 --> 00:23:55,560
Speaker 2: in the clinic for twenty minutes make sure everything's good.

440
00:23:55,840 --> 00:23:56,520
Speaker 3: They're good, they go.

441
00:23:57,320 --> 00:24:01,919
Speaker 2: But that's why you know, I won't let patients do

442
00:24:02,040 --> 00:24:06,200
Speaker 2: shots at home because you know, God forbid something would happen.

443
00:24:06,320 --> 00:24:08,439
Speaker 2: You have to be somewhere where someone can take, you know,

444
00:24:08,520 --> 00:24:11,560
Speaker 2: help you take care of that reaction.

445
00:24:12,920 --> 00:24:16,040
Speaker 1: Doctor Chris Colosso is our guest. He has been very

446
00:24:16,119 --> 00:24:17,960
Speaker 1: kind to stay with us this long. We will have

447
00:24:18,080 --> 00:24:20,040
Speaker 1: one more segment with him so he can get back

448
00:24:20,040 --> 00:24:23,360
Speaker 1: to his patients. If you want to connect with him,

449
00:24:23,440 --> 00:24:27,200
Speaker 1: it's spelled co l Aco. It's Advanced Asthma and Allergy.

450
00:24:27,680 --> 00:24:30,000
Speaker 1: Or you can email me through our website Michael Berryshow

451
00:24:30,000 --> 00:24:32,640
Speaker 1: dot com and I will connect you with him. One

452
00:24:32,680 --> 00:24:37,320
Speaker 1: more segment with doctor Colosso. Come Out Joy Kung Alma

453
00:24:37,680 --> 00:24:44,320
Speaker 1: Michael Bay Good Show on Talk Plum. Doctor Chris Colosso

454
00:24:44,640 --> 00:24:49,119
Speaker 1: is my wife's allergist and now my allergist and he

455
00:24:49,400 --> 00:24:54,960
Speaker 1: has managed phenomenal healing for her. And I asked him

456
00:24:54,960 --> 00:24:57,320
Speaker 1: at my last appointment if he would come on and

457
00:24:57,400 --> 00:24:59,639
Speaker 1: share with you some of his experiences and some of

458
00:24:59,680 --> 00:25:03,000
Speaker 1: these stories, especially with it now being full blown uh

459
00:25:03,200 --> 00:25:06,600
Speaker 1: allergy season. Uh Doc, I want to go. I want

460
00:25:06,600 --> 00:25:08,600
Speaker 1: to move kind of fast here because I'm going through

461
00:25:08,640 --> 00:25:13,280
Speaker 1: my report and a legal disclaimer. I have told doctor

462
00:25:13,320 --> 00:25:15,680
Speaker 1: colosso he can talk about my case because they don't

463
00:25:15,720 --> 00:25:19,200
Speaker 1: like to do that. The first thing that you test

464
00:25:19,320 --> 00:25:22,160
Speaker 1: for on indoor allergens is dust might.

465
00:25:22,240 --> 00:25:22,720
Speaker 3: Why is that.

466
00:25:24,440 --> 00:25:27,680
Speaker 2: Because in Houston, dust might is a you know, a

467
00:25:27,920 --> 00:25:32,400
Speaker 2: very common allergen that people get sensitized to. And dust

468
00:25:32,480 --> 00:25:35,240
Speaker 2: mites are around anywhere in the country where it's very humid.

469
00:25:35,280 --> 00:25:38,080
Speaker 2: They're actually even and you know, you can have it

470
00:25:38,160 --> 00:25:41,320
Speaker 2: in New Mexico, but they tend to the population tends

471
00:25:41,359 --> 00:25:44,200
Speaker 2: to be very high in places where it's very humid,

472
00:25:44,920 --> 00:25:47,159
Speaker 2: and you know, you think about it, dust mites is

473
00:25:47,200 --> 00:25:49,399
Speaker 2: an indoor allergyen and so all might you sleep, you

474
00:25:49,520 --> 00:25:53,160
Speaker 2: bleed it in and that's why you have a good

475
00:25:53,320 --> 00:25:57,000
Speaker 2: chance of becoming allergic to it. And because that exposure

476
00:25:57,080 --> 00:25:59,840
Speaker 2: is they're chronically and so that's why it's one of

477
00:25:59,880 --> 00:26:04,520
Speaker 2: the major indoor allergens all over the country that would

478
00:26:04,640 --> 00:26:08,800
Speaker 2: drive allergies, and so that's why most allergists will check for.

479
00:26:08,920 --> 00:26:12,080
Speaker 1: Dust might The next thing on the list was dog hair.

480
00:26:12,200 --> 00:26:14,560
Speaker 1: Fortunately I'm not allergic to that, but I am allergic

481
00:26:14,640 --> 00:26:17,040
Speaker 1: to cat hair, which was the one after that. How

482
00:26:17,480 --> 00:26:20,640
Speaker 1: often is that flaring for people are coming up as positive?

483
00:26:22,240 --> 00:26:25,560
Speaker 2: Cat is a very common allergen, and most people will

484
00:26:25,800 --> 00:26:28,560
Speaker 2: will know this cat and cat allergen tends to be

485
00:26:29,160 --> 00:26:32,399
Speaker 2: a little bit worse for patients than dog allergen. And

486
00:26:32,400 --> 00:26:36,240
Speaker 2: then partly that's because cat allergen is very very sticky,

487
00:26:36,960 --> 00:26:39,880
Speaker 2: and so it tends to sort of spread all over

488
00:26:39,960 --> 00:26:43,479
Speaker 2: the house very quickly, and so patients can even if

489
00:26:43,560 --> 00:26:46,320
Speaker 2: you you know someone who's very allergic to cat, if

490
00:26:46,400 --> 00:26:50,040
Speaker 2: you sit in the side in a car and someone

491
00:26:50,119 --> 00:26:52,880
Speaker 2: who had a cat and you have a cat allergy,

492
00:26:53,600 --> 00:26:57,040
Speaker 2: you will notice that evening that you have more symptoms well,

493
00:26:57,400 --> 00:27:00,440
Speaker 2: and so so that's the thing, and that's that's real thing.

494
00:27:00,520 --> 00:27:04,159
Speaker 1: The next was roach mix and mixed feathers. Why are

495
00:27:04,240 --> 00:27:05,000
Speaker 1: those so high?

496
00:27:06,320 --> 00:27:09,840
Speaker 2: So roach mix we you know, tend to do again

497
00:27:09,920 --> 00:27:12,440
Speaker 2: because you know roaches, if you know some people you

498
00:27:13,080 --> 00:27:15,080
Speaker 2: exposed to it in an apartment. I mean, most of

499
00:27:15,400 --> 00:27:17,440
Speaker 2: you know, our patient my patients pray for roaches, so

500
00:27:17,520 --> 00:27:20,160
Speaker 2: that's not a problem. But if it is positive, then

501
00:27:20,640 --> 00:27:23,680
Speaker 2: it's it's an It's an allergen that can drive sort

502
00:27:23,720 --> 00:27:27,440
Speaker 2: of allergy and asthma a lot, and so you know,

503
00:27:27,440 --> 00:27:29,800
Speaker 2: if it is positive, I tell patients to do stuff

504
00:27:29,880 --> 00:27:33,639
Speaker 2: to you know, mitigate roaches. Feathers sometimes is not a

505
00:27:33,960 --> 00:27:37,480
Speaker 2: very strong allergen. But if you have a lot of

506
00:27:37,560 --> 00:27:41,000
Speaker 2: down comforters and pillows and those kinds of things, and

507
00:27:41,119 --> 00:27:43,800
Speaker 2: you're getting worse at night when you sleep.

508
00:27:43,600 --> 00:27:45,720
Speaker 3: And may not be the best thing for you to do.

509
00:27:46,480 --> 00:27:48,960
Speaker 1: So in your listing off those were the indoor allergens

510
00:27:49,080 --> 00:27:50,800
Speaker 1: you test for, and you said to me that what

511
00:27:51,000 --> 00:27:52,840
Speaker 1: you test for is about ninety five percent of what

512
00:27:52,920 --> 00:27:54,359
Speaker 1: people are going to have. You could test for a

513
00:27:54,440 --> 00:27:56,680
Speaker 1: million things, but this is what it makes the most sense.

514
00:27:57,040 --> 00:28:00,439
Speaker 1: In your listing of trees, live oak followed by pecan

515
00:28:00,600 --> 00:28:03,560
Speaker 1: than white ash, did you list these in order of

516
00:28:03,760 --> 00:28:07,600
Speaker 1: how likely someone typically is to get them or how

517
00:28:08,240 --> 00:28:10,560
Speaker 1: how prevalent these trees are, Although I guess that would

518
00:28:10,640 --> 00:28:11,600
Speaker 1: those would be the same thing.

519
00:28:11,680 --> 00:28:16,080
Speaker 2: Maybe I think it's more, those are the most common

520
00:28:16,119 --> 00:28:18,720
Speaker 2: ones in Houston, and I didn't I didn't at the time.

521
00:28:18,800 --> 00:28:21,760
Speaker 2: I didn't think about, you know, just based on prevalence.

522
00:28:21,840 --> 00:28:24,639
Speaker 2: But I just listed the most common trees when I

523
00:28:24,720 --> 00:28:26,800
Speaker 2: first set out, you know, the practice. You know, I've

524
00:28:26,840 --> 00:28:30,439
Speaker 2: got with a botanist from Greer, who's you know, one

525
00:28:30,480 --> 00:28:34,000
Speaker 2: of the major companies that supply ology extracts, and so they,

526
00:28:34,200 --> 00:28:36,560
Speaker 2: you know, tell you which are the most prevalent trees

527
00:28:36,600 --> 00:28:38,920
Speaker 2: in the area and those kind of things on what

528
00:28:39,080 --> 00:28:42,520
Speaker 2: you should be testing for. And but you know, oak,

529
00:28:42,600 --> 00:28:44,280
Speaker 2: ash and pecan are the ones that are you know,

530
00:28:44,480 --> 00:28:46,440
Speaker 2: very common, and so that's what the ones we pay.

531
00:28:46,720 --> 00:28:49,160
Speaker 1: Interestingly, I don't even like pine, and that was one

532
00:28:49,160 --> 00:28:51,680
Speaker 1: of the only trees I was not allergic to. You

533
00:28:51,800 --> 00:28:56,240
Speaker 1: then went from there to grasses, Bermuda, Johnson vernal mix

534
00:28:56,960 --> 00:29:03,000
Speaker 1: and bahia, Saint Augustine within that, Am I am I

535
00:29:03,120 --> 00:29:03,800
Speaker 1: mixing that up?

536
00:29:03,880 --> 00:29:04,280
Speaker 3: Or is that not?

537
00:29:04,440 --> 00:29:04,480
Speaker 1: So?

538
00:29:04,800 --> 00:29:05,360
Speaker 3: No, there's no.

539
00:29:05,680 --> 00:29:08,280
Speaker 2: So Saint Augustine is a you know as a broad

540
00:29:08,400 --> 00:29:11,600
Speaker 2: leaf grass, and Saint Augustine would have to grow a

541
00:29:11,720 --> 00:29:13,480
Speaker 2: foot before it pollinatees.

542
00:29:14,240 --> 00:29:17,320
Speaker 3: So most most you know won't, No one ever lets

543
00:29:17,320 --> 00:29:19,840
Speaker 3: it grow that long. And so that's why we don't.

544
00:29:19,880 --> 00:29:22,040
Speaker 2: So so a lot of people will say, oh, I

545
00:29:22,120 --> 00:29:25,360
Speaker 2: feel bad when I cut the grass, it may not.

546
00:29:25,560 --> 00:29:26,160
Speaker 3: Actually be that.

547
00:29:26,280 --> 00:29:28,640
Speaker 2: And most of us have Saint Augustine, you know, or

548
00:29:28,960 --> 00:29:32,080
Speaker 2: you know that's the most common grass, but it's actually

549
00:29:32,160 --> 00:29:34,720
Speaker 2: sometimes if you're if you don't have a good harm

550
00:29:34,800 --> 00:29:36,720
Speaker 2: and you have a lot of you know, bermuda or

551
00:29:36,760 --> 00:29:39,320
Speaker 2: some other wild grasses in there, that is what is

552
00:29:39,400 --> 00:29:42,560
Speaker 2: causing the symptoms. And then sometimes one of the other tricks,

553
00:29:42,600 --> 00:29:45,920
Speaker 2: because it rains so much here, sometimes these broad leaf

554
00:29:46,000 --> 00:29:50,440
Speaker 2: grasses grow mold on them. And so even though Saint

555
00:29:50,440 --> 00:29:54,120
Speaker 2: Augustine doesn't pollinate, it's when you're when it's being cut,

556
00:29:54,440 --> 00:29:57,000
Speaker 2: you're pouring off a lot of mold. Oh, and that

557
00:29:57,200 --> 00:29:58,480
Speaker 2: would be what's the reacting to.

558
00:29:58,760 --> 00:30:01,520
Speaker 1: And then we move to the weed. You have ragweed first,

559
00:30:01,600 --> 00:30:05,480
Speaker 1: and pigweed then marsh elder I've always heard of, you know,

560
00:30:05,840 --> 00:30:07,160
Speaker 1: ragweed is one of the things that a lot of

561
00:30:07,200 --> 00:30:09,400
Speaker 1: people will tell you they're allergic to.

562
00:30:10,280 --> 00:30:13,600
Speaker 3: Is that the number one ragweed is the number one.

563
00:30:13,640 --> 00:30:17,280
Speaker 2: And also just historically, you know, whenever they show pictures

564
00:30:17,360 --> 00:30:22,320
Speaker 2: on the news, the ragweed pollen looks like the spike ball.

565
00:30:22,800 --> 00:30:26,040
Speaker 2: So it's very sort of photogenic and look something like

566
00:30:26,160 --> 00:30:26,480
Speaker 2: something you.

567
00:30:26,480 --> 00:30:27,280
Speaker 3: Know to attack you.

568
00:30:27,840 --> 00:30:32,200
Speaker 2: And so that's why ragweed is the most known fall pollen.

569
00:30:32,600 --> 00:30:35,640
Speaker 2: And the way I listed those things was spring, summer,

570
00:30:35,720 --> 00:30:39,240
Speaker 2: and fall. So in the broad sense, trees are typically

571
00:30:39,320 --> 00:30:42,240
Speaker 2: in spring, except cedar and elm, which are from fall.

572
00:30:43,040 --> 00:30:46,680
Speaker 2: Grasses are in summer, and then weeds are in full

573
00:30:47,520 --> 00:30:51,640
Speaker 2: So that was, you know, the listing of how I

574
00:30:51,800 --> 00:30:54,560
Speaker 2: did you know or when we tested people for allergies.

575
00:30:54,640 --> 00:30:56,520
Speaker 1: I want to skip past modes and come back to

576
00:30:56,600 --> 00:30:59,120
Speaker 1: it in a moment and go to foods. That's one

577
00:30:59,160 --> 00:31:01,560
Speaker 1: of the things that a lot of people feel that

578
00:31:01,760 --> 00:31:05,680
Speaker 1: they have an allergy to. And I noted, you've got milk, eggs,

579
00:31:05,720 --> 00:31:10,040
Speaker 1: soy peanut. I read recently that we didn't have peanut

580
00:31:10,080 --> 00:31:12,800
Speaker 1: allergies one hundred years ago, and the reason is because

581
00:31:12,840 --> 00:31:16,120
Speaker 1: one of the vaccines we take as children affects us.

582
00:31:16,360 --> 00:31:19,600
Speaker 1: And it's not the peanut we're allowed we're allergic to.

583
00:31:20,120 --> 00:31:22,880
Speaker 1: It's the copper in it. Do you believe there's anything

584
00:31:22,960 --> 00:31:23,120
Speaker 1: to that.

585
00:31:25,760 --> 00:31:26,680
Speaker 3: I don't think so.

586
00:31:27,720 --> 00:31:30,680
Speaker 2: And the reason for that is because you can have

587
00:31:31,200 --> 00:31:32,800
Speaker 2: microscopic amounts of.

588
00:31:35,720 --> 00:31:38,960
Speaker 3: Peanut and you'll react to the protein now.

589
00:31:40,520 --> 00:31:44,400
Speaker 2: There's more chance that it is the hygiene because if

590
00:31:44,440 --> 00:31:48,760
Speaker 2: you look so so if you look at the again

591
00:31:48,960 --> 00:31:55,520
Speaker 2: in India and let's say in China, so it's interesting, right,

592
00:31:55,560 --> 00:31:59,080
Speaker 2: they don't have much peanut allergy. And again in India,

593
00:31:59,160 --> 00:32:03,040
Speaker 2: it's because when you have more of you know, the

594
00:32:03,160 --> 00:32:06,280
Speaker 2: dirt and those kind of things, you are suppressing this

595
00:32:06,560 --> 00:32:09,280
Speaker 2: arm of the immune system, so it's not trying to

596
00:32:09,440 --> 00:32:16,320
Speaker 2: react to those foods. In China, per capita, they probably

597
00:32:16,400 --> 00:32:19,480
Speaker 2: eat the most peanuts that anyone does in the world,

598
00:32:19,560 --> 00:32:23,600
Speaker 2: but they have very low no peanut allergies. And partially

599
00:32:23,720 --> 00:32:28,520
Speaker 2: it's because they eat boiled peanuts. When you boil a peanut,

600
00:32:29,320 --> 00:32:33,840
Speaker 2: you denature that antigen that people tend to get allergic to,

601
00:32:34,880 --> 00:32:39,040
Speaker 2: whereas roasting a peanut brings the antigen.

602
00:32:38,640 --> 00:32:40,880
Speaker 3: That you react to perfectly on the surface.

603
00:32:41,240 --> 00:32:42,880
Speaker 1: But I lack them roasted so much better.

604
00:32:42,960 --> 00:32:47,000
Speaker 3: Dot I know, I know that that's part of the thing.

605
00:32:47,640 --> 00:32:49,760
Speaker 3: And even now they tend you.

606
00:32:49,800 --> 00:32:53,680
Speaker 2: Know, incorporating some of those foods early. You know, now

607
00:32:53,760 --> 00:32:56,800
Speaker 2: the new guidelines are that you know, if the child

608
00:32:56,920 --> 00:32:59,720
Speaker 2: is not allergic to the food, you incorporate some of

609
00:32:59,760 --> 00:33:04,400
Speaker 2: that stuff much earlier, right, and that may help you not,

610
00:33:05,080 --> 00:33:06,960
Speaker 2: you know, react to those foods.

611
00:33:07,040 --> 00:33:10,280
Speaker 1: I promised I would keep you no longer, and you

612
00:33:10,440 --> 00:33:13,400
Speaker 1: have been wonderful. Doctor Chris Colosso c O L L

613
00:33:13,560 --> 00:33:19,160
Speaker 1: A COO Advanced asthma and allergy. He's been a magic

614
00:33:19,760 --> 00:33:23,400
Speaker 1: uh maker for my wife and now he's my doctor.

615
00:33:23,640 --> 00:33:26,960
Speaker 1: And obviously you can see why he has. He's passionate

616
00:33:27,040 --> 00:33:29,200
Speaker 1: about this and I hate allergies. Thank you for being

617
00:33:29,240 --> 00:33:31,760
Speaker 1: our guests, my man, Thank you very much