1 00:00:00,280 --> 00:00:02,800 Speaker 1: It's Wednesday in some medical news with doctor Jim Keeney, 2 00:00:02,880 --> 00:00:05,720 Speaker 1: chief medical officer for Dignity Saint Mary Medical Center in 3 00:00:05,800 --> 00:00:09,640 Speaker 1: Long Beach and a board certified er doctor of which 4 00:00:09,640 --> 00:00:12,280 Speaker 1: you practiced or medicine for a whole bunch of years decades. 5 00:00:12,320 --> 00:00:17,279 Speaker 2: Good morning, Jim. All right, So shingles vaccine. 6 00:00:17,280 --> 00:00:19,600 Speaker 1: I want to talk about that because it is are 7 00:00:19,640 --> 00:00:23,840 Speaker 1: people do people not get vaccinated for shingles because of 8 00:00:23,920 --> 00:00:28,160 Speaker 1: any fantastic connection between autism and some kind of other 9 00:00:28,240 --> 00:00:30,280 Speaker 1: disease or is that just something that falls under the. 10 00:00:30,560 --> 00:00:34,600 Speaker 3: Radar Now it's mostly just suppress old folks and most 11 00:00:34,600 --> 00:00:38,040 Speaker 3: people aren't at that age, aren't worried about autism at 12 00:00:38,040 --> 00:00:41,280 Speaker 3: that point, and they just you know, anyone who's seen 13 00:00:41,320 --> 00:00:45,680 Speaker 3: a friend who's gotten shingles, they feel the misery and say, hey, 14 00:00:45,720 --> 00:00:48,480 Speaker 3: I don't want that. So it's pretty well adopted. 15 00:00:49,159 --> 00:00:51,400 Speaker 1: Okay, Yeah, on what I was thinking of, not that 16 00:00:51,440 --> 00:00:53,760 Speaker 1: they're going to be afraid of autism, but that's that 17 00:00:53,800 --> 00:00:59,600 Speaker 1: connection to autism, that philosophy that's going through the medical 18 00:00:59,640 --> 00:01:04,480 Speaker 1: science or non medical science today and shingles. It seems, 19 00:01:04,840 --> 00:01:07,640 Speaker 1: you know, when I first heard the word shingles, it 20 00:01:07,680 --> 00:01:08,920 Speaker 1: seems fairly benign. 21 00:01:09,440 --> 00:01:11,960 Speaker 2: It could be pretty serious stuff and painful as hell. 22 00:01:12,040 --> 00:01:12,720 Speaker 2: I understand. 23 00:01:13,880 --> 00:01:16,920 Speaker 3: Yeah, what people describe. They say that when like their 24 00:01:17,000 --> 00:01:19,840 Speaker 3: clothes touch their skin, it feels like a blowtorch is 25 00:01:19,880 --> 00:01:23,880 Speaker 3: being like wafted across their skin at an intense, severe 26 00:01:24,440 --> 00:01:28,760 Speaker 3: burning pain, and it's disabling. It keeps people awake at night, 27 00:01:28,959 --> 00:01:32,280 Speaker 3: it distracts them all day long. It's pretty severe. So 28 00:01:32,959 --> 00:01:35,080 Speaker 3: it's something most people want to try and avoid. But 29 00:01:35,120 --> 00:01:38,360 Speaker 3: there's the secondary problems, right of inflammation in your body, 30 00:01:38,360 --> 00:01:42,600 Speaker 3: and we know that inflammation contributes to cardiovascular disease and 31 00:01:42,760 --> 00:01:45,679 Speaker 3: the effects of you know, of having heart attacks or strokes. 32 00:01:46,240 --> 00:01:50,120 Speaker 3: So there is evidence, it's it's association evidence. It's not 33 00:01:50,200 --> 00:01:55,520 Speaker 3: randomized controlled trials that seemed to show that with these 34 00:01:55,600 --> 00:01:58,640 Speaker 3: vaccines you have a reduced incidence of other problems like 35 00:01:58,680 --> 00:02:01,560 Speaker 3: heart attack or stroke. And then this recent study that 36 00:02:01,720 --> 00:02:05,200 Speaker 3: brought us back up shows that the genetic markers and 37 00:02:05,320 --> 00:02:08,040 Speaker 3: inflammation and all these other things that seem to reduce 38 00:02:08,440 --> 00:02:12,160 Speaker 3: what's called your biological age. So that's a bunch of 39 00:02:12,200 --> 00:02:15,240 Speaker 3: markers that were, you know, again not one hundred percent 40 00:02:15,440 --> 00:02:19,600 Speaker 3: scientifically vetted, but it's it's interesting. 41 00:02:20,080 --> 00:02:24,000 Speaker 1: Jim, there is something that actually is linked to autism 42 00:02:24,040 --> 00:02:26,239 Speaker 1: for real, although you know, any link to autism today 43 00:02:26,280 --> 00:02:30,040 Speaker 1: seems to just fall on deaf fears because of what's 44 00:02:30,080 --> 00:02:33,400 Speaker 1: going on. But let's talk about the connection, a real connection. 45 00:02:34,440 --> 00:02:37,840 Speaker 3: Sure. So I mean, first we should say autism is 46 00:02:38,080 --> 00:02:41,000 Speaker 3: mostly genetic. We know that because when we look at 47 00:02:41,160 --> 00:02:44,519 Speaker 3: twin studies where you know you're either a fraternal twin 48 00:02:44,639 --> 00:02:48,720 Speaker 3: or identical twin. Fraternal twins share some genes, but identical 49 00:02:48,760 --> 00:02:51,160 Speaker 3: twins have the exact same genes, they have a much 50 00:02:51,320 --> 00:02:55,920 Speaker 3: higher rate of correlating autism between the two twins. So 51 00:02:56,400 --> 00:02:58,680 Speaker 3: then we have, on top of the genes, which is 52 00:02:58,680 --> 00:03:02,880 Speaker 3: the biggest thing, you're environmental factors and that can affect 53 00:03:02,880 --> 00:03:06,240 Speaker 3: your epigenetics and other things. What this study did was 54 00:03:06,240 --> 00:03:09,359 Speaker 3: looked at women who, especially in the third trimester, we're 55 00:03:09,400 --> 00:03:14,839 Speaker 3: exposed to smoke and the wildfires, and looked at them 56 00:03:14,919 --> 00:03:17,040 Speaker 3: for the next five years to see if the children 57 00:03:17,080 --> 00:03:19,480 Speaker 3: had a high rate of developing autism, and they did. 58 00:03:20,040 --> 00:03:22,400 Speaker 3: So it does seem that, and we've known this before, 59 00:03:22,440 --> 00:03:26,240 Speaker 3: that high levels of pollution and smoke will increase your 60 00:03:26,320 --> 00:03:28,560 Speaker 3: risk for autism. And this is just another study that 61 00:03:28,600 --> 00:03:32,119 Speaker 3: shows there are environmental factors that will increase your risk 62 00:03:32,200 --> 00:03:32,760 Speaker 3: for autism. 63 00:03:33,680 --> 00:03:38,400 Speaker 1: So wildfires and smoke in terms of not only what 64 00:03:38,520 --> 00:03:43,640 Speaker 1: is it, cardiovasculars issues certainly pulmonary issues, and now autism. 65 00:03:43,760 --> 00:03:45,680 Speaker 2: So the trick is to get away from wildfires. 66 00:03:47,040 --> 00:03:51,600 Speaker 3: Yeah. Medical, It was a good study. They did two 67 00:03:51,680 --> 00:03:55,400 Speaker 3: hundred people in two hundred thousand people in southern California 68 00:03:55,560 --> 00:03:59,920 Speaker 3: during wildfires, not these most recent ones, but wildfire time, 69 00:04:00,160 --> 00:04:03,200 Speaker 3: and they followed them. So mean a pretty powerful study. 70 00:04:03,200 --> 00:04:06,160 Speaker 3: But it's an observational study. Again, this is not randomized 71 00:04:06,480 --> 00:04:11,240 Speaker 3: controlled trials. So it shows association, it doesn't necessarily link 72 00:04:11,280 --> 00:04:14,280 Speaker 3: the cause. But with this this big of a number, 73 00:04:14,720 --> 00:04:19,680 Speaker 3: it really does beg the question that smoke seems to correlate. 74 00:04:20,480 --> 00:04:25,320 Speaker 1: Okay, last and certainly the least probably And this is 75 00:04:25,360 --> 00:04:27,080 Speaker 1: what Jim sends me. 76 00:04:27,560 --> 00:04:29,400 Speaker 2: And this is and I don't know what it is. 77 00:04:29,600 --> 00:04:32,680 Speaker 1: The secret weapon to fight a cold is inside your 78 00:04:32,760 --> 00:04:36,280 Speaker 1: nose and it's not your finger, I'm assuming, right. 79 00:04:37,600 --> 00:04:41,159 Speaker 3: Right, that's one way. No, so well, we've known this 80 00:04:41,160 --> 00:04:42,920 Speaker 3: for a little while, but a study just came out 81 00:04:42,960 --> 00:04:45,839 Speaker 3: looking at the grew nose cells in a plate and 82 00:04:45,880 --> 00:04:49,159 Speaker 3: then exposed it to rhinovirus and saw you know which 83 00:04:49,400 --> 00:04:52,599 Speaker 3: cells got infected and which cells didn't. So it's pretty 84 00:04:52,640 --> 00:04:56,200 Speaker 3: far removed from your actual nose. And what they found 85 00:04:56,240 --> 00:04:59,599 Speaker 3: were certain factors. Number one is that the cells produce 86 00:05:00,120 --> 00:05:03,240 Speaker 3: a protein called interferon, and we've known about interfere on 87 00:05:03,320 --> 00:05:06,279 Speaker 3: since its seventies. And if they produce the interferre on, 88 00:05:06,360 --> 00:05:08,800 Speaker 3: you don't get a you don't get cold. If they 89 00:05:08,839 --> 00:05:11,920 Speaker 3: don't produce interfere on, then you're more likely to get it. 90 00:05:12,279 --> 00:05:14,159 Speaker 3: The other issue is if you had a recent cold, 91 00:05:14,200 --> 00:05:15,800 Speaker 3: you still have it, or if these cells have been 92 00:05:15,839 --> 00:05:18,560 Speaker 3: recently exposed to a virus, you still have that interferre 93 00:05:18,600 --> 00:05:21,240 Speaker 3: on hanging around, so when you expose them a second time, 94 00:05:21,680 --> 00:05:24,480 Speaker 3: less likely to get a cold. And then the exposure 95 00:05:24,880 --> 00:05:29,279 Speaker 3: during like if we change the temperature, colder temperatures seem 96 00:05:29,360 --> 00:05:34,080 Speaker 3: to increase the risk of getting the rhinovirus. So this 97 00:05:34,160 --> 00:05:36,280 Speaker 3: is not exactly or shattering, but it was interesting. I 98 00:05:36,279 --> 00:05:38,840 Speaker 3: thought it was an interesting study that your nose actually 99 00:05:38,839 --> 00:05:41,920 Speaker 3: produces the interfere on. Next question is, well, why don't 100 00:05:41,920 --> 00:05:43,600 Speaker 3: we just make interfere on that you spray in your 101 00:05:43,600 --> 00:05:46,040 Speaker 3: nose so that you don't get a cold, And they've 102 00:05:46,080 --> 00:05:49,560 Speaker 3: tried that, people have tried that. The problem is that 103 00:05:50,000 --> 00:05:52,760 Speaker 3: you can't have too high a concentration because interfere on 104 00:05:52,760 --> 00:05:55,760 Speaker 3: in your system interferes with your immune system as well, 105 00:05:55,839 --> 00:05:58,160 Speaker 3: so and it has a lot of outside effects. 106 00:05:58,200 --> 00:06:01,520 Speaker 1: So all right, that mar okay, it's that sweet spot 107 00:06:01,560 --> 00:06:06,000 Speaker 1: that nature provides, that kind of hate when nature does 108 00:06:06,000 --> 00:06:08,360 Speaker 1: anything as opposed to the rest of us doing all 109 00:06:08,400 --> 00:06:12,920 Speaker 1: man made stuff. Jim, thank you as always, and we'll 110 00:06:12,920 --> 00:06:15,680 Speaker 1: catch you again next Wednesday, and we always do this. 111 00:06:16,000 --> 00:06:16,720 Speaker 2: You have a good day. 112 00:06:17,160 --> 00:06:17,960 Speaker 3: Take care, take care.