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Speaker 1: This is a podcast from WR Now more of the

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Speaker 1: WR Saturday Morning Show and Larry Minte Welcome back. The

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Speaker 1: Reverend Jesse Jackson died this week from something called supra

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Speaker 1: nuclear palsy. Doctor Gregory Poland from the Mayo Clinic is

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Speaker 1: here to explain what that is. Doctor Poland, I just

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Speaker 1: found out that you were recently diagnosed with prostate cancer

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Speaker 1: and went through surgery.

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Speaker 2: Everything okay, yes, fortunately, I mean I do, of course

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Speaker 2: what the science shows and what we advise patients to have.

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Speaker 2: I've been followed very closely for about twelve years, and

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Speaker 2: finally the PSA went up a little bit and the

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Speaker 2: MRI just a little bit abnormal, had the prostate removed,

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Speaker 2: fortunately a very geny teeny focus of cancer. So had

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Speaker 2: a prostotectomy and cured and doing well.

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Speaker 1: So you're doing well. What happens when you have your

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Speaker 1: prostate removed? Well, how does that affect you? Well?

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Speaker 2: The most common thing is that you have some difficulty

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Speaker 2: with urinary incontinence for a while. In my case, of course,

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Speaker 2: I went to an excellent institution to have the surgery.

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Speaker 2: It was really minimal and only for a few weeks,

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Speaker 2: and then recovered.

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Speaker 1: Wonderful Oh, that is wonderful. I guess because of what

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Speaker 1: you did and the fact that you were able to

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Speaker 1: catch this in time, you have a message to everyone else.

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Speaker 2: And that's exactly why I'm talking about it, you know, publicly,

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Speaker 2: is to encourage people. This This is something that's it's

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Speaker 2: something that you have to for men have to watch

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Speaker 2: for and be screened for. By the way, I should say,

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Speaker 2: because I myself sort of worried about what would the

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Speaker 2: biopsy be like. And I can tell you and promise

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Speaker 2: you done properly. I had not a millisecond of discomfort really,

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Speaker 2: So don't be afraid of it. Get get screened, talk

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Speaker 2: with your doctor about it. Certainly if there's a family

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Speaker 2: history of prostate cancer. African American men have a much

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Speaker 2: higher incidence for unknown reasons of prostate cancer, so it's

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Speaker 2: really important for them to talk with their doctor and

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Speaker 2: figure out what kind of screening is best for them.

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Speaker 1: And the tests are fairly easy, right except for the

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Speaker 1: biopsy part.

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Speaker 2: It's a blood test right and then and the biopsy

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Speaker 2: they use consciousdation much like a colonoscopy, so you don't

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Speaker 2: feel anything, and they go through the perineum that area

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Speaker 2: between the rectum and the scrotum and they put a

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Speaker 2: needle through there. They use ultrasound guidance. They take a

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Speaker 2: little piece of the abnormality, and then a pathologist looks

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Speaker 2: at it under the microscope and then you make a

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Speaker 2: decision about partial gland therapy, radiation therapy, or surgical removed.

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Speaker 2: And I opted for surgical removal.

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Speaker 1: So Jesse Jackson, I'm so glad to hear that. By

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Speaker 1: the way, I should point that that's wonderful. That is wonderful.

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Speaker 1: What is super nuclear palsy the disease that Jesse Jackson

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Speaker 1: died of. Yeah, well, the Reverend Jackson, from what we read,

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Speaker 1: had been diagnosed with Parkinson's disease in twenty seventeen. It

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Speaker 1: probably was early progressive super nuclear palsy. Life expectancy with

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Speaker 1: that diagnosis is around seven eight years, so that also fits.

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Speaker 1: The basic underlying cause of it is a protein we

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Speaker 1: normally have called the TAU protein that becomes disregulated and

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Speaker 1: misfolded so that it actually destroys brain cells and you

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Speaker 1: get these tangles of these proteins, so a lot like

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Speaker 1: what happens in Alzheimer's disease and what happen weapons as

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Speaker 1: they develop a stiffness, difficulty walking, they have difficulty raising

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Speaker 1: their eyes, and they have cognitive problems and tend to

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Speaker 1: fall oddly enough, they tend to fall backwards, not forwards.

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Speaker 1: No known cure at this point, so it's a very

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Speaker 1: unfortunate diagnosis. But the Reverend Jackson lived about as long

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Speaker 1: as as anybody does with this disease. Yeah, it's interesting,

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Speaker 1: you said in twenty seventeen, because I have interviewed Jesse

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Speaker 1: Jackson several times, and in twenty twenty at the Democratic

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Speaker 1: National Convention, I interviewed him and I really couldn't make

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Speaker 1: out what he was saying. It was unusable at that point,

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Speaker 1: so he was still doing interviews, but I don't think

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Speaker 1: anybody was able to use it.

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Speaker 2: Yeah, so unfortunately it is.

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Speaker 1: And let's talk about one last thing because it's important.

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Speaker 1: So you could have a higher possibility at dementia depending

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Speaker 1: on what you choose to drink.

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Speaker 2: Maybe I would say it a different way that the

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Speaker 2: risk of dementia or cognitive decline was lower, about eighteen

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Speaker 2: fourteen percent lower. And people who drank caffeinated coffee and

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Speaker 2: caffeinated tea. Now that bothered me because I only drink

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Speaker 2: decaffeinated drinks because I carry a gene variant where I

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Speaker 2: don't metabolize caffeine very well. If I drank what my

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Speaker 2: wife drinks, She's Norwegian and drinks this black coffee. If

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Speaker 2: I drank that, I literally would be hospitalized. So choose

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Speaker 2: your poison, just really quickly.

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Speaker 1: Doctor. Birdflow was suspected in the in dead geese found

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Speaker 1: in New Jersey. Something to be concerned about.

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Speaker 2: Yes, you know, we continue to have outbreaks. It's a

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Speaker 2: significant outbreak of what's called high pathogenicity avian flu. The

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Speaker 2: US since twenty twenty four has lost about ninety million birds,

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Speaker 2: which is why he hate costs, you know, go up

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Speaker 2: and down. But importantly Larry. It has affected mammals, dairy cows,

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Speaker 2: and about seventy human cases as of late twenty twenty

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Speaker 2: five in the US. So it's this disease primarily of

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Speaker 2: birds of zoonosis that is modifying slowly and the concern

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Speaker 2: that many of us carry. Would this ever mutate to

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Speaker 2: be easily transmittable in humans that happens, we have a

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Speaker 2: significant pandemic. Well, let's pray that it doesn't.

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Speaker 1: Doctor Gregory Poland health and medical expert who is a

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Speaker 1: leader in vaccines and infectious diseases at the Mayo Clinic.

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Speaker 1: He's also president of the Atria Research Institute in New York.

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Speaker 1: This has been a podcast from wor