Speaker 1: Diabetes ever been a contender for type two?
Speaker 2: Just eat mate, you'll get get to fix meat yep,
Speaker 2: eat more fats, right. Cholesterol, Get cholesterol in you that
Speaker 2: will fix your diabetes. Get cholesterols into you, India, get
Speaker 2: cholesterol into you that'll fix your diabetes.
Speaker 1: Well, I think we might have a chat with Professor
Speaker 1: Alif Akinschi, who's from the Australian Senate for Accelerating Diabetes
Speaker 1: Innovations at the University of Melbourne, because they've got a
Speaker 1: new way to treat diabetes type two, which I've fan
Speaker 1: quite fascinating. Professor, Good morning.
Speaker 3: Good morning, Thanks for inviting me.
Speaker 1: No worries. What's the best way to avoid diabetes type two?
Speaker 1: First up?
Speaker 3: So the best way really is to think about lifestyle measures,
Speaker 3: so really increasing physical activity, eating healthy diet, avoiding ultra
Speaker 3: process foods, avoiding sugar drinks and so forth. That is
Speaker 3: really the best way to prevent getting diabetes in the
Speaker 3: first place. It's also highly relevant if you do have diabetes, right.
Speaker 1: Insulin injections can be very d traumatic, particularly for people
Speaker 1: when they're knew to diabetes too, but you're working on
Speaker 1: trying to avoid those Is that correct?
Speaker 3: Yeah, there is a clinical trial that we did, which
Speaker 3: we did the first phase, first in human clinical trial
Speaker 3: at the Austin which is a hospital where I work at,
Speaker 3: and I'm presenting the trial results at the American Diabetes
Speaker 3: Association meeting in Chicago this week. And in that trial,
Speaker 3: what we did was using electrical pulses to regenerate the
Speaker 3: lining of the duodenum. So it's through an endoscopic procedure,
Speaker 3: like a gastroscopy type of procedure, which is requiring a
Speaker 3: general anesthetic. It lasts about an hour and a catheter
Speaker 3: goes into the duodenal wall and it produces electrical pulses
Speaker 3: which is really used to eliminate the poorly functioning cells
Speaker 3: and that allows the regrowth of the new and healthy
Speaker 3: cells usually within days. That helps the body make its
Speaker 3: own hormones that are really relevant to help manage the datiatis.
Speaker 4: So these are essentially for the layman out there, regenerating
Speaker 4: the cells in your.
Speaker 3: Gut, that's right. Yeah.
Speaker 4: And so with the treatment, how say invasive is it
Speaker 4: for a potential patient?
Speaker 3: Yeah, so it is an invasive procedure because you need
Speaker 3: a gastroscopy, you know, and a general anesthetic. But it
Speaker 3: is being generally well tolerated. For the patients that we've
Speaker 3: had in our trial, they go home on the same
Speaker 3: day they have the treatment and you know, a few
Speaker 3: days later and weeks later, the glucose levels improved. It it
Speaker 3: is sort of like a regenerative procedure of the lining
Speaker 3: of the small gut, particularly in the first part joodenum.
Speaker 4: So with that treatment though, but going back to your
Speaker 4: initial point, if you cut out the sugars, reduced carbohydrates,
Speaker 4: as much as you can donate your process foods, healthy fats,
Speaker 4: these are all keys to making sure your gut healthy.
Speaker 3: Is good exactly. Yeah, they're they're really important things. So
Speaker 3: in some people though, when they've had diabetes for a
Speaker 3: long time, their management using medications or those injections like
Speaker 3: a zembic or insulance is just not enough to keep
Speaker 3: the blood sugars still under control. And so this is
Speaker 3: a new way of thinking about treatment that could really
Speaker 3: help people in that situation.
Speaker 1: How excited are you, bidily, Yeah, we're pretty excited.
Speaker 3: It's you know, first in the world really to show this,
Speaker 3: and you know, us and at the Austin at Saint
Speaker 3: Vincents in Melbourne and investigators that in Sydney and it
Speaker 3: is really exciting. Now it's an international trial, which is
Speaker 3: the next phase, which is a pivotal trial, and it's
Speaker 3: recruiting at the moment and if people wanted to find out,
Speaker 3: they can go to www. Dot reset study dot com.
Speaker 3: It's R E. C to study dot com. And you know,
Speaker 3: I think look at is early days. It is we
Speaker 3: need to do more trial than this. The next phase
Speaker 3: of the trial is a randomized control trial, which is
Speaker 3: you know, the dummy controlled one, which is really important
Speaker 3: for us to really know if this is working. But yeah,
Speaker 3: we're quite excited about it.
Speaker 1: Good on your best of luck you've made in Chicago before.
Speaker 3: Yes, I have yes beautiful architecture.
Speaker 1: Yeah, I come ale to enjoy it. Mate, we'll talk
Speaker 1: against and good luck with the good luck with the study.