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Speaker 1: You're listening to a Mumma mea podcast.

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Speaker 2: Hey, I'm Taylor Strano.

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Speaker 3: This is Mumma MIA's twice daily news podcast, The Quickie.

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Speaker 3: In the space of twenty four hours, we've had two

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Speaker 3: very different messages about weight loss injection drugs. The World

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Speaker 3: Health Organization has just endorsed them as long term obesity treatments,

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Speaker 3: while Australia's Medicine's watchdog has updated its warnings to flag

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Speaker 3: a potential risk of suicidal thought and behaviors. So what's

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Speaker 3: actually going on here and what does it mean if

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Speaker 3: you're already on one of these medications or thinking about it.

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Speaker 2: Plus, the Oxford.

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Speaker 3: Word of the Year has dropped and people are raging

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Speaker 3: over it. An Aussie pop culture queen will drop by

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Speaker 3: to decode before we get there, Here's Claire Murphy with

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Speaker 3: the latest from The Quickie news room for Wednesday, December three.

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Speaker 1: Thanks Taylor. A suppression order has been lifted, allowing reporting

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Speaker 1: on the dark history of Greg Lynn, the former Jetstar

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Speaker 1: pilot found guilty of the death of elderly camp at

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Speaker 1: Carol Clay in the Victorian high Country in twenty twenty.

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Speaker 1: During Lynn's trial, where he was also charged with the

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Speaker 1: disappearance of Russell Hill and later acquitted of his death.

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Speaker 1: It was suppressed that he'd reportedly made many threats against

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Speaker 1: his ex wife, who was later found dead under suspicious circumstances.

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Speaker 1: Lisa Lynne told her mother that he'd threatened to kill

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Speaker 1: her on multiple occasions, threatening to cut out her eyes

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Speaker 1: with an ornamental sword she'd once given him as a gift.

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Speaker 1: Her mother also overheard threats herself, hearing Lynn allegedly say

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Speaker 1: that her daughter's blood would flow in the streets. Lisa

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Speaker 1: also wrote in her diary that greg Lynn had threatened

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Speaker 1: to kill her with a shotgun, and that he told

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Speaker 1: her that he knew where her parents and sisters lived

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Speaker 1: so he knew how to get to her. Following years

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Speaker 1: of what Lisa's family described as verbal abuse and shocking cruelty,

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Speaker 1: Lisa left greg Lynn, whose violent behavior escalated, at one

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Speaker 1: stage forcing his way into Lisa's home with a sledgehammer

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Speaker 1: and continually threatening to kill or hurt her. Police did

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Speaker 1: take out an intervention or, but Lisa's father said when

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Speaker 1: he reported the death threats to police, they told him

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Speaker 1: that if he kills her, then we can do something.

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Speaker 1: Eight months after leaving Lisa filed for divorce. Later that

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Speaker 1: same month, her body was found lying on the front

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Speaker 1: lawn of her home, her toddler children alone inside. Her

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Speaker 1: death was ruled a suicide after toxicology results showed she

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Speaker 1: had alcohol and pharmaceutical drugs in her system, but her

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Speaker 1: family says things went missing from the home that night,

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Speaker 1: including answering machine, tapes that she'd kept of Lynn's threats,

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Speaker 1: and her current diary. After Lynn was arrested over the

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Speaker 1: murders in twenty twenty, Victorian police launched a new investigation

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Speaker 1: into Lisa's death. Disgraced former political staffer Bruce Lehman will

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Speaker 1: learn today whether an appeal to overturn a court ruling

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Speaker 1: that he probably raped colleague Britney Higgins is successful after

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Speaker 1: suing Network ten and journalist Lisa Wilkinson for defamation over

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Speaker 1: an interview with Higgins on the Project. In twenty twenty one,

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Speaker 1: Justice Michael Lee found Miss higgins claims that Lehman had

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Speaker 1: raped her inside Parliament House two years earlier were established

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Speaker 1: on the balance of probabilities. Lehmann appealed the finding during

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Speaker 1: a two day hearing in August, arguing the judge erd

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Speaker 1: in finding ten and Miss Wilkinson had legally justified the

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Speaker 1: imputation of rape. The appeal judges were told Justice Lee's

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Speaker 1: factual findings differed from the case run against him, including

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Speaker 1: that he'd committed a non violent rape against Miss Higgins.

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Speaker 1: The ruling depicted a violent rape. Tens Barrister argue that

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Speaker 1: labeling the suggestion that Lehman may have given different testimony

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Speaker 1: was astonishing. After months of deliberations, the full Court of

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Speaker 1: the Federal Court of Appeal will hand down its decision today.

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Speaker 1: Palestinian militant group HAMAS says its handing over the remains

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Speaker 1: of one of the last two hostages bodies still in

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Speaker 1: the Galza Strip. Israeli Prime Minister Benjamin Netanyahu's offers said

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Speaker 1: in a statement that its forces have received what they've

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Speaker 1: described as findings that would be taken into Israel for

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Speaker 1: forensic testing. The two remaining deceased hostages were both kidnapped

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Speaker 1: during Hamas's October seven, twenty twenty three attack on Israel.

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Speaker 1: Violence in the enclave has reduced Sinceno Toba ten ceasefire,

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Speaker 1: but Israel has continued to strike the Gaza Strip and

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Speaker 1: conduct demolitions against what it says is Hamas infrastructure. Hamas

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Speaker 1: and Israel have traded a blame for violating the US

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Speaker 1: backed agreement. At least three hundred and fifty seven Palestinians

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Speaker 1: have been killed since the ceasefire between Israel and Hamas

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Speaker 1: went into effect. The Prata Group has officially purchased Milan

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Speaker 1: fashion rival Versacei in a one point twenty five billion

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Speaker 1: Euro deal. The move puts the fashion house known for

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Speaker 1: its sexy silhouettes under the same roof as Prada's ugly

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Speaker 1: chic aesthetic and Newmu's youth driven appeal. The highly anticipated

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Speaker 1: deal expected to relaunch Forversarti's fortunes after a slow post

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Speaker 1: pandemic performance. As part of the US luxury group Capri Holdings,

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Speaker 1: Prata Air Lorenzo Bertelli will steer Versarti's next phase as

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Speaker 1: executive chairman, as well as his roles as group marketing

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Speaker 1: director and sustainability chief. Miley Cyrus is engaged. A source

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Speaker 1: has told people that the thirty three year old is

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Speaker 1: engaged to musician Max Mirando, just days after she'd stepped

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Speaker 1: out at the U s Avatar Fire and Ashweld premiere

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Speaker 1: sporting a diamond ring. The couple posing for photos together

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Speaker 1: as she flashed her new bling. Cyrus was romantically linked

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Speaker 1: to the drummer back in December twenty twenty one. Pictured

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Speaker 1: getting cozy backstage during her NBC holiday special. She told

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Speaker 1: British Fogue in twenty twenty three that they met on

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Speaker 1: a blind date.

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Speaker 2: Thanks Claan Next.

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Speaker 3: GLP on's have dominated headlines all year, and these new

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Speaker 3: updates might be the most significant yet. If you feel

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Speaker 3: like ozembic type drugs are everywhere right now, you're not wrong.

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Speaker 2: They've been called breakthrough.

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Speaker 3: Medications to diabetes and obesity, used by hundreds of thousands

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Speaker 3: of Australians, and they've turned their makers into trillion dollar giants.

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Speaker 3: The World Health Organization has just released its first ever

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Speaker 3: guidelines on these medicines, known as GLP one receptor agonists,

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Speaker 3: and in striking timing, only twenty four hours after Australian's

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Speaker 3: Therapeutic Goods Administration updated its warnings for the very same drugs.

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Speaker 3: Let's start with what the World Health Organization has said.

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Speaker 3: They've issued conditional recommendations to use three GLP one drugs lirigluetide, semigluetide,

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Speaker 3: antizephytide as long term treatments for obesity and adults. That's

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Speaker 3: in package with a healthy diet, physical activity, and ongoing

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Speaker 3: support from health professionals to play translator. When the WHO

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Speaker 3: says conditional, what they mean is the benefits probably outweigh

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Speaker 3: the risks, but long term data is limited and there

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Speaker 3: are still unknowns. The question then becomes, will why endorse them? Well,

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Speaker 3: because for many people living with obesity, GLP one medicines

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Speaker 3: deliver weight loss we've never seen before with medication.

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Speaker 2: And improved blood sugar, blood pressure, and.

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Speaker 3: Other risk factors, which can mean fewer heart attacks, strokes

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Speaker 3: and complications down the line. The WHO also points out

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Speaker 3: cost and access are a huge issue in Australia. These

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Speaker 3: rugs can cost anywhere from one hundred and thirty to

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Speaker 3: two hundred maybe even more a month if you're not subsidized,

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Speaker 3: that's more than two grand a year, making it difficult

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Speaker 3: for many people to stay on them for prolonged periods.

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Speaker 3: The guidelines call for deliberate policies to make access fairer,

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Speaker 3: calling on the global community for urgent action on manufacturing, affordability,

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Speaker 3: and system readiness to meet global needs. Now a little

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Speaker 3: closer to home, here's what the Therapeutic Goods Administration has

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Speaker 3: to say. On Monday, the regulator issued a safety alert

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Speaker 3: for GLP one based medications, flagging a potential risk of

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Speaker 3: suicidal thoughts or behaviors. The medications currently marked include semigluetide

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Speaker 3: sold as ozepic and wigovi, lyriglutide soldis sixender, dulagluetide known

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Speaker 3: as Trilicity, and tazeppetide aka Manjaro. Patients are being told

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Speaker 3: to contact their health professional if they notice new or

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Speaker 3: worsening depressions, suicidal thoughts, or unmutual changes in mood or behavior. Now,

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Speaker 3: the important bit here is the TGA says there is

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Speaker 3: not enough evidence to conclude these drugs cause those changes.

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Speaker 3: In other words, they're not saying this definitely happens. They're saying,

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Speaker 3: we can't completely rule it out, so we're formally putting

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Speaker 3: it on your radar. They point out there's a complex

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Speaker 3: relationship between mental illness and the conditions these drugs treat,

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Speaker 3: type two diabetes and obesity, and even possibly that weight

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Speaker 3: loss itself could be associated with suicidal thoughts in some people.

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Speaker 3: This warning comes after the TGA's database of adverse events notifications.

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Speaker 2: Retrieved eighty five reports back in.

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Speaker 3: September, including everything from suicidal ideation to depressional suicide. The

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Speaker 3: TGA has looked at international data, including a mixed bag

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Speaker 3: of studies. Some show no link it all between GLP

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Speaker 3: one medications and mental health problems, while other recent studies

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Speaker 3: did find higher rates of depression, anxiety, and suicidality, possibly

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Speaker 3: related to changes in brain chemicals like dopamine. The FDA

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Speaker 3: in the un US has also reviewed cases of suicidal

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Speaker 3: thoughts in people taking these medicines, and so far it

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Speaker 3: says it hasn't found evidence they cause suicidal behavior, but

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Speaker 3: it also can't rule out.

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Speaker 2: A small risk, so it's still watching closely.

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Speaker 3: On top of the mental health warning, there's another key

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Speaker 3: update for ta zeppa'side being sold as Monjarro down under.

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Speaker 3: The TGA says it can't rule out a reduced effectiveness

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Speaker 3: of oral contraception when you first start or when your

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Speaker 3: dose is increased. Patients on the pill whose startmanjarro are

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Speaker 3: now advised to switch to a non oral contraceptive or

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Speaker 3: at a barrier method for four weeks after first taking it,

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Speaker 3: and for four weeks after each dose increase.

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Speaker 2: Do goos.

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Speaker 3: The latest were joined by Royal Australian College of GP's

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Speaker 3: Chair of the Specific Interests Obesity Management, doctor.

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Speaker 2: Terry Lynn South. Terry, let's start with the who.

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Speaker 3: This is the first time we're seeing any sort of

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Speaker 3: guidance on obesity and weight loss injections.

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Speaker 2: What do you make of the announcements?

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Speaker 4: What I like particularly about the world health organizations. It

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Speaker 4: is a forty nine page document, but what it's really

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Speaker 4: highlighting is that obesit is should be considered a long term, chronic,

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Speaker 4: relapsing medical condition and that we need to be thinking

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Speaker 4: about interventions that are lifelong. It's always on a basis

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Speaker 4: from a lifestyle point of view, so that means changes

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Speaker 4: from an eating point of view, exercising behavior change, having

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Speaker 4: supportive environments that enables that to happen. But there is

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Speaker 4: a role of very effective and what seems to be

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Speaker 4: safe adjunct to add on OBC management medications, particularly the

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Speaker 4: GLP one medications, so relatively safe with the deep information

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Speaker 4: that we had up to date. This is an interim

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Speaker 4: advice because things are still moving relatively quickly, needing a

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Speaker 4: little bit more time to get somevidence. So it's conditional

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Speaker 4: though who is expecting to update this advice every twelve

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Speaker 4: months because we're still waiting for real world evidence of

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Speaker 4: these higher medications, because we've really only had two to

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Speaker 4: four years of evidence with regards to long term effects

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Speaker 4: and safety.

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Speaker 3: One of the things that came as part of the

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Speaker 3: guidelines is this call for urgent action around making access

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Speaker 3: and manufacturing and policy across the world to make access

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Speaker 3: to these medications greater and fairer and quicker. How could

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Speaker 3: this maybe change the way that people access or those

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Speaker 3: drugs are prescribed here? Then we know that obviously in

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Speaker 3: Australia people already being prescribed GLP one medications for weight loss,

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Speaker 3: So does this change anything?

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Speaker 4: What it changes is we're having a very respected medical

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Speaker 4: organization really calling out that there is inequity for a

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Speaker 4: very effective medication, that the cost is an issue, that

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Speaker 4: access is an issue, and it's really about affordability, certainly

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Speaker 4: in Australia. So there are no medication that are on

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Speaker 4: the PBS Medication Cost Subsidies scheme that are for obesity management.

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Speaker 4: And then now that we actually have some effective medications

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Speaker 4: that seem to be relatively safe and there is a

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Speaker 4: real desire for patients to actually try and get that

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Speaker 4: medication into the hands of the people who need it most.

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Speaker 3: I want to move on Terry to a little bit

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Speaker 3: closer to home and talking about some of those TGA

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Speaker 3: flags that have been put on our radar this week

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Speaker 3: as well, one of them being about a potential risk

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Speaker 3: of suicidal thoughts and behaviors linked to people taking GLP

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Speaker 3: one medications. Now that comes off the back of looking

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Speaker 3: in their own database. The TGA found eighty five accounts

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Speaker 3: of people experiencing these sort of side effects. That feels

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Speaker 3: like a pretty small group size. Is it enough to

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Speaker 3: flag a risk?

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Speaker 4: Yeah? What I like about the TGA is that they

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Speaker 4: were looking at other international guidelines and they felt that

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Speaker 4: that class of medications, of which if they are prescribed

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Speaker 4: for different reasons, some of it may be with regards

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Speaker 4: to type two diabetas, some of it in regards to

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Speaker 4: IBC management plus other medications, and it was a little

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Speaker 4: bit unequal in regards to any advice around worsening mental health,

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Speaker 4: including worsening of suicide all thoughts. So the TIGA are

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Speaker 4: wanting to suggest that it may be what we call

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Speaker 4: a class effect. And I do think that even though

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Speaker 4: the risk does seem to be relatively low. What I

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Speaker 4: must say is a provisional or association, not necessarily a

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Speaker 4: cause or link worsening suicide. All avigation is so important

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Speaker 4: because that's a potentially life threatening and a condition. So

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Speaker 4: I do think it's a very important prescribers to be

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Speaker 4: aware of that as well as the general public because

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Speaker 4: I feel as THO that this medication is you're getting

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Speaker 4: a lot of hype and we need to understand that

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Speaker 4: all medications have pros, cons and potential side effects. So

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Speaker 4: any decision making about the appropriateness of this medication for

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Speaker 4: an individual needs to take in consideration their individual risks.

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Speaker 4: The goals of using their medication is and particularly for

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Speaker 4: most people, it's expected to be long term management.

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Speaker 3: And finally, for you, Terry, I want to talk about

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Speaker 3: the other thing that the TJA has been up in

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Speaker 3: the news for this week, which is about the contraceptives

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Speaker 3: and Munjara. We've heard about the Ozenbic baby boom people

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Speaker 3: getting pregnant after being on weight loss Maids, but now

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Speaker 3: this is a specific flag about the effectiveness of oral

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Speaker 3: contraceptives while taking to zeppaside. Specifically, what can you tell

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Speaker 3: us about that.

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Speaker 4: To zeppotide is a different molecule from the other injectable,

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Speaker 4: so it is not just a glp agonis working on

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Speaker 4: that particular hormone in the body, but also a GIP,

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Speaker 4: so it's what we call a dueling CRETN and it

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Speaker 4: does seem to have potentially greater what we call gastric

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Speaker 4: ding delay, so it slows down the release of food

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Speaker 4: as well as other gastric contents, and this is where

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Speaker 4: the oral medication may have the digestion and therefore the

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Speaker 4: absorption of that drug slowed down, and therefore the levels

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Speaker 4: of the oral contraceptive pill may not be in the

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Speaker 4: same peak concentrations because of that side effect called gastrienting,

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Speaker 4: and therefore the again it's a potential risk. It has

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Speaker 4: been proven that the oral contraceptive pill may not be

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Speaker 4: as effective with regards to preventing pregnancy and people who

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Speaker 4: weren't taking Monterray.

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Speaker 3: If the story has raised anything for you, help is available.

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Speaker 3: You can contact lifline. On thirteen eleven fourteen, we finally

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Speaker 3: arrived at our final installment of Word for the Year,

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Speaker 3: and it's a doozy Ento Oxford's twenty twenty five Word

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Speaker 3: of the Year rage bait. After crunching the numbers and

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Speaker 3: telling the data The language experts over at the Oxford

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Speaker 3: University Press aka the publishers of the Oxford Dictionary, shortlisted

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Speaker 3: three contenders for the top gong, rage bait or farming

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Speaker 3: and biohack. Of the thirty thousand people who voted, the

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Speaker 3: two worded rage bait has come out on top. But

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Speaker 3: what does it actually mean and why people so pissed?

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Speaker 3: According to Oxford, rage bait is defined as online content

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Speaker 3: deliberately designed to elicit anger or outrage by being frustrating, provocative,

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Speaker 3: or offensive, typically posted in order to increase traffic two

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Speaker 3: or engagement with a particular web page or social media content.

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Speaker 2: Right with the formalities out of the way, how do

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Speaker 2: we actually feel about it?

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Speaker 3: Host of The Moment podcast and Queen of Culture, Mif

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Speaker 3: Warhurst has a thing or two to say, mif there

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Speaker 3: is something cosmic about.

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Speaker 2: This year's word of the year, are you in fact raging?

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Speaker 1: You know?

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Speaker 4: I am?

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Speaker 5: I'm boiling up from the inside over this one, mostly

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Speaker 5: because these very esteemed organizations such as Oxford University, which

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Speaker 5: has given us rage bait this year, Cambridge Dictionary, Colin's Dictionary,

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Speaker 5: dot Com, I'm a bits us on but I trusted them.

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Speaker 5: They've told me, as I've grown up, how I should

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Speaker 5: say things, how things are spelled, and they're very, very

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Speaker 5: picky about those things. And now all of a sudden,

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Speaker 5: two words for the word of the year, and the

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Speaker 5: most esteemed of them all Oxford University Press has given

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Speaker 5: us rage bait. I think purely to rage bait us.

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Speaker 5: I'm sure of it.

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Speaker 3: That's it, right, like ironic, because you famously are not

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Speaker 3: a fan of a two word word of the Year winner,

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Speaker 3: so this must have you see them.

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Speaker 5: I was quite upset and I looked up why and

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Speaker 5: it makes sense, but it's also still unacceptable given how

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Speaker 5: the dictionaries treated us over the years, and they're very

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Speaker 5: strict with their rules. But now it's laisse fairies you like.

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Speaker 5: But apparently two words are an expression and an expression

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Speaker 5: are a single unit of meaning. So I don't know, Taylor, like,

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Speaker 5: do we buy that? I think we kind of have to.

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Speaker 5: I think we're also still allowed to get upset.

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Speaker 2: It almost feels like double dipping a little bit.

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Speaker 5: It does. You're right, It's like putting the hand in

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Speaker 5: and taking more than you deserve and passing your germs around.

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Speaker 5: That's a good analogy.

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Speaker 3: Maybe we need to like remarket word of the year

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Speaker 3: then just to kind of like vibe of the year

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Speaker 3: or phrase of the year, like I don't know, because

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Speaker 3: that's not a word, it's two words.

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Speaker 5: Exactly, And I think you're right, that's what I was thinking.

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Speaker 5: We should call it the phrase of the year something

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Speaker 5: along those lines, or the moment of the year. Coincidentally,

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Speaker 5: these seem to be more about capturing what the zeitgeist

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Speaker 5: is rather than what the word is, So I think

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Speaker 5: that might be where I'm getting a little bit annoyed,

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Speaker 5: but annoyed in a funny way. It's nice to talk

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Speaker 5: about words, and that's why I've enjoyed being annoyed, because

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Speaker 5: when do you get to talk about dictionaries? When do

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Speaker 5: you get to talk about words which we grow up

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Speaker 5: on and we learn to love and we learn to

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Speaker 5: express ourselves with. They are magical.

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Speaker 3: I feel like when word of the Year rolls around,

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Speaker 3: all of our linguist friends out there go off final

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Speaker 3: you guys have something to talk about when it comes

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Speaker 3: to words. But you're right, it taps into this thing

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Speaker 3: of the zeitgeist of twenty twenty five.

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Speaker 2: Do you feel like rage bait is the right words

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Speaker 2: to do that.

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Speaker 5: This year, I think it's on trend. It's very much

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Speaker 5: something that has existed for quite a long time. I

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Speaker 5: think rage bait has driven the algorithm for a long time.

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Speaker 5: I guess maybe now we're only coming to realize it.

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Speaker 5: And it's quite a sad indictment of where we are

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Speaker 5: culturally because algorithms do rule what we see. Given the

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Speaker 5: for you page is now where it's at in terms

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Speaker 5: of how we access information. We're not necessarily following our

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Speaker 5: friends as much. Instagram has changed that, but what still

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Speaker 5: works online is rage bait. People engage with rage bait,

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Speaker 5: and that's what people are doing on purpose now in

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Speaker 5: order to get people to interact. And I think it's

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Speaker 5: actually quite a depressing and a sad indictment on where

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Speaker 5: we're at right now because that's the only way you

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Speaker 5: can get noticed. And I think then it means that

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Speaker 5: good things, positive things, happy things left to the s

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Speaker 5: side and don't get the same exposure because you know,

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Speaker 5: rage bait's exactly that it clicks something in your brain

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Speaker 5: and you're there and you're like, oh, I hate that.

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Speaker 5: I want to say something or I want to attack,

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Speaker 5: but you watch it till the end rather than something

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Speaker 5: that maybe you don't and it's sad. Rage bait is sad.

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Speaker 5: So yeah, not a great word.

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Speaker 3: Before we let you go, miff, we know that rage

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Speaker 3: bait is not your word the edge.

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Speaker 2: Do you have a Word of the ed? Do you participate?

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Speaker 1: Oh?

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Speaker 2: Goodness made? Do I have?

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Speaker 5: I hadn't actually thought about that. Do I have a

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Speaker 5: word of the year?

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Speaker 2: Well taken on? Notice you can email it through.

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Speaker 5: I will I will see. I'm also a fifty two

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Speaker 5: year old woman. My brain fog is real and at

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Speaker 5: this stage in life, as you would know, you've probably

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Speaker 5: got coworkers that are in a similar situation. We have

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Speaker 5: some of the best ideas about ten hours later when

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Speaker 5: it comes to us, when we can finally remember and

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Speaker 5: we've gone into the filo facts and it's able to

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Speaker 5: be accessed.

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Speaker 3: Thanks for taking some time to feed your mind with

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Speaker 3: us today. The Quickie is produced by me Table Strano,

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Speaker 3: Laria Broofi and Clare Murphy, with audio production.

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Speaker 4: By hill.

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Speaker 2: Momma.

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Speaker 1: Mea acknowledges the traditional owners of land and waters that

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Speaker 1: this podcast is recorded on