WEBVTT - Psychedelics, peptides and brain health with Dr Sarah McKay

0:00:00.720 --> 0:00:03.160
<v Speaker 1>Why is it so hard to get real answers about

0:00:03.200 --> 0:00:06.560
<v Speaker 1>your health? If you've been told that everything looks fine,

0:00:06.760 --> 0:00:09.680
<v Speaker 1>but you know that something is off, we're not imagining it.

0:00:09.880 --> 0:00:13.200
<v Speaker 1>That's why I created Vitality three sixty to help you

0:00:13.240 --> 0:00:16.439
<v Speaker 1>better understand what's going on inside your body so that

0:00:16.520 --> 0:00:19.680
<v Speaker 1>you can take the targeted action needed. With a functional

0:00:19.680 --> 0:00:23.560
<v Speaker 1>health approach plus testing, we go beyond the guesswork to

0:00:23.680 --> 0:00:26.960
<v Speaker 1>uncover the root causes of your symptoms. I've teamed up

0:00:26.960 --> 0:00:31.160
<v Speaker 1>with Doctyesmina, an incredible integrative GP and together we will

0:00:31.200 --> 0:00:34.879
<v Speaker 1>help you decode your body's signals and answer questions like

0:00:35.120 --> 0:00:38.880
<v Speaker 1>why am I always exhausted? What's really causing my stubborn weight?

0:00:39.159 --> 0:00:43.520
<v Speaker 1>Am I inflamed? Insulin resistant? Or maybe missing key nutrients?

0:00:43.680 --> 0:00:46.800
<v Speaker 1>Because when you understand your body better, you can transform

0:00:46.840 --> 0:00:49.680
<v Speaker 1>your health. Visit v three sixty dot health or check

0:00:49.720 --> 0:00:53.120
<v Speaker 1>out the show notes for more. This is Healthy Heir

0:00:53.200 --> 0:00:55.760
<v Speaker 1>with Amelia Phillips and welcome to one of my mini

0:00:55.880 --> 0:00:59.920
<v Speaker 1>motivation episodes. These are shorter, targeted episodes where we tackle

0:01:00.120 --> 0:01:04.039
<v Speaker 1>one specific question or challenge head on. Today we're bringing

0:01:04.080 --> 0:01:09.440
<v Speaker 1>in neuroscientist doctor Sarah Mackai to discuss psychedelics, peptides and

0:01:09.640 --> 0:01:10.280
<v Speaker 1>brain health.

0:01:10.480 --> 0:01:12.240
<v Speaker 2>Doctor Sarah is the author of three.

0:01:12.080 --> 0:01:15.280
<v Speaker 1>Books on brain health, including her latest book, Brain Health

0:01:15.319 --> 0:01:17.119
<v Speaker 1>for Dummies, published earlier this year.

0:01:17.240 --> 0:01:18.040
<v Speaker 2>She was also.

0:01:17.880 --> 0:01:20.759
<v Speaker 1>Recently on the Mel Robins podcast and has a fabulous

0:01:20.760 --> 0:01:23.880
<v Speaker 1>Instagram page which I'll pop the link into the show

0:01:23.920 --> 0:01:27.360
<v Speaker 1>notes for you. It's all about helping our female brains thrive.

0:01:27.640 --> 0:01:31.120
<v Speaker 1>So here is what doctor Sarah had to say about psychedelics,

0:01:31.200 --> 0:01:49.640
<v Speaker 1>peptides and brain health. Psychedelics, they are such a hot.

0:01:49.480 --> 0:01:51.080
<v Speaker 2>Topic at the moment. You know, we've got.

0:01:50.920 --> 0:01:54.520
<v Speaker 1>Things such as psilocyburn, which is the active compound in

0:01:54.560 --> 0:01:58.200
<v Speaker 1>magic mushrooms. You've got MDMA in ecstasy, and they're now

0:01:58.280 --> 0:02:02.880
<v Speaker 1>being used in select clinic settings to treat disorders such

0:02:02.920 --> 0:02:06.720
<v Speaker 1>as treatment resistant depression and PTSD. And I have to

0:02:06.720 --> 0:02:11.280
<v Speaker 1>say there's some quite encouraging research and success coming out

0:02:11.320 --> 0:02:15.079
<v Speaker 1>of some of these clinical trials. Can you please give

0:02:15.160 --> 0:02:19.520
<v Speaker 1>us a very kind of broad overview of what's actually

0:02:19.600 --> 0:02:23.600
<v Speaker 1>going on at a neurological level when we are putting

0:02:23.760 --> 0:02:25.680
<v Speaker 1>these psychedelics into our body.

0:02:25.840 --> 0:02:27.960
<v Speaker 3>Yeah, Australia is one of the very few countries in

0:02:28.000 --> 0:02:30.040
<v Speaker 3>the world. I'm actually I haven't followed it for a while,

0:02:30.360 --> 0:02:34.640
<v Speaker 3>that's kind of given the go ahead, yes, a betrayal, yeah,

0:02:34.800 --> 0:02:40.120
<v Speaker 3>to some very select well trained psychiatrist working and the

0:02:40.240 --> 0:02:43.160
<v Speaker 3>space to use you know, these these as a kind

0:02:43.200 --> 0:02:45.080
<v Speaker 3>of a treatment. It's not like you're going out to

0:02:45.200 --> 0:02:48.600
<v Speaker 3>woollies and buying some magic mushrooms to you know, help

0:02:48.639 --> 0:02:52.079
<v Speaker 3>your recovery from your PTSD. That's not the sort of

0:02:52.160 --> 0:02:54.160
<v Speaker 3>the state where I haven't looked into this for quite

0:02:54.200 --> 0:02:56.560
<v Speaker 3>a while. But the long story short is, particularly when

0:02:56.560 --> 0:02:58.880
<v Speaker 3>we're looking at psychedelics, they put the brain and this

0:02:59.000 --> 0:03:02.680
<v Speaker 3>kind of very very very plastic state almost the same

0:03:02.760 --> 0:03:05.920
<v Speaker 3>type of state where a lot of the brain because

0:03:05.919 --> 0:03:07.960
<v Speaker 3>we haven't talked so much about brain networks, so that

0:03:07.960 --> 0:03:09.720
<v Speaker 3>the different parts of the brain that kind of connect

0:03:09.720 --> 0:03:12.280
<v Speaker 3>and communicate with each other, they become very kind of

0:03:12.360 --> 0:03:15.959
<v Speaker 3>hyper connected and almost go into a state of plasticity

0:03:15.960 --> 0:03:19.240
<v Speaker 3>whereby they can kind of form new pathways and new

0:03:19.560 --> 0:03:24.000
<v Speaker 3>ways of talking to each other. Kind it becomes far

0:03:24.040 --> 0:03:27.080
<v Speaker 3>more malleable, and the networks can kind of react and

0:03:27.120 --> 0:03:30.919
<v Speaker 3>reorganize far more efficiently instead of becoming quite set in

0:03:30.960 --> 0:03:33.799
<v Speaker 3>their ways. And perhaps say someone's got PTSD and there's

0:03:33.840 --> 0:03:36.640
<v Speaker 3>a like that kind of trauma scenario playing over and

0:03:36.680 --> 0:03:38.000
<v Speaker 3>over and over and over in their mind, and the

0:03:38.080 --> 0:03:39.839
<v Speaker 3>tried all of the other things. It puts the brain

0:03:39.920 --> 0:03:42.320
<v Speaker 3>in this state of plasticity where like kind of a

0:03:42.360 --> 0:03:45.760
<v Speaker 3>new pathway could be much more easily formed, and it's

0:03:45.800 --> 0:03:48.320
<v Speaker 3>not simply a matter of throwing the psychedelic and the

0:03:48.320 --> 0:03:50.320
<v Speaker 3>brain will do that. It needs to be needs the

0:03:50.360 --> 0:03:52.960
<v Speaker 3>talk therapy and needs the therapy at the same Yeah,

0:03:53.000 --> 0:03:55.720
<v Speaker 3>because my understanding is, you know, these go for a

0:03:55.800 --> 0:03:58.080
<v Speaker 3>few months, and so someone will have like quite a

0:03:58.160 --> 0:04:02.520
<v Speaker 3>significant dose of either the PSILOCYBERM or the MDMA, and

0:04:02.560 --> 0:04:05.400
<v Speaker 3>then over a two to six hour period, they're in

0:04:05.440 --> 0:04:07.920
<v Speaker 3>a room with you know, all the props, whether it's

0:04:08.000 --> 0:04:13.240
<v Speaker 3>music or sound or light, and the psychiatst psychiatrists most importantly,

0:04:13.600 --> 0:04:19.400
<v Speaker 3>asking very considered and specific questions to help unlock whatever

0:04:19.480 --> 0:04:21.440
<v Speaker 3>that issue. And then you know, they I think, I

0:04:21.440 --> 0:04:23.400
<v Speaker 3>can't remember if it's every three weeks or six weeks

0:04:23.480 --> 0:04:26.480
<v Speaker 3>or probably the treatments are changing and varied, but they

0:04:26.520 --> 0:04:30.160
<v Speaker 3>go through a few of these dose sessions over a

0:04:30.240 --> 0:04:33.839
<v Speaker 3>couple of months. And so it's this combination of the

0:04:33.880 --> 0:04:37.920
<v Speaker 3>psychiatrist's input that is helping when the brain's I guess

0:04:37.920 --> 0:04:40.200
<v Speaker 3>it's a bit like hot yoga, right when your muscles

0:04:40.200 --> 0:04:42.960
<v Speaker 3>are all loose and supple and you're able to stretch.

0:04:43.000 --> 0:04:46.280
<v Speaker 3>A bit further is that kind of brain becomes. If

0:04:46.320 --> 0:04:49.240
<v Speaker 3>you google what happens to the brain on psychedelics, there's

0:04:49.240 --> 0:04:53.400
<v Speaker 3>this really famous figure that I saw. The researcher who

0:04:53.480 --> 0:04:56.000
<v Speaker 3>created that figure, I was on Twitter or linkedln or

0:04:56.040 --> 0:04:58.080
<v Speaker 3>something not that long ago. Going to snow become one

0:04:58.120 --> 0:05:00.920
<v Speaker 3>of the most shared images and all the neuroscience because

0:05:00.920 --> 0:05:04.240
<v Speaker 3>it kind of shows this kind of really colorful rainbow

0:05:04.360 --> 0:05:06.880
<v Speaker 3>image of the different brain networks becoming much more kind

0:05:06.920 --> 0:05:09.599
<v Speaker 3>of hyper connected with each other. So it's like they

0:05:09.720 --> 0:05:12.520
<v Speaker 3>kind of go into this the state of like kind

0:05:12.520 --> 0:05:15.880
<v Speaker 3>of flux and flexibility that enables the brain to create

0:05:16.240 --> 0:05:19.159
<v Speaker 3>a much newer, healthier pattern and wave connected.

0:05:19.160 --> 0:05:19.760
<v Speaker 2>And I can't.

0:05:19.600 --> 0:05:22.920
<v Speaker 1>Imagine if it's got the power to create these newer

0:05:23.000 --> 0:05:25.080
<v Speaker 1>and healthier patterns, I can imagine there's a bit of

0:05:25.160 --> 0:05:27.560
<v Speaker 1>risk involved as well, because what if it has the opposite,

0:05:27.600 --> 0:05:29.559
<v Speaker 1>what if it creates an even work.

0:05:29.760 --> 0:05:33.480
<v Speaker 3>This is why you know, people you might do so psychedelics,

0:05:33.560 --> 0:05:34.960
<v Speaker 3>you have a bad trip and you can end up

0:05:35.000 --> 0:05:37.760
<v Speaker 3>seeing the psychiatrist because you know you've got a psychosis

0:05:37.839 --> 0:05:40.080
<v Speaker 3>or something. So you know, you don't know which way

0:05:40.080 --> 0:05:41.280
<v Speaker 3>it's going to go, and that's what it needs to

0:05:41.320 --> 0:05:43.680
<v Speaker 3>be done in this kind of really controlled and regulated way,

0:05:44.040 --> 0:05:48.400
<v Speaker 3>and lots of psychoactive psychoactive drugs and substances work in

0:05:48.440 --> 0:05:51.240
<v Speaker 3>these ways. There's this really interesting theory. This is not

0:05:51.279 --> 0:05:52.600
<v Speaker 3>what I know you were going to ask me about,

0:05:52.600 --> 0:05:55.280
<v Speaker 3>but it just time. It's a really interesting theory about

0:05:55.279 --> 0:05:59.920
<v Speaker 3>even SSRIs. So lots of people find SSRI, selective serotonin

0:06:00.040 --> 0:06:03.719
<v Speaker 3>reuptake inhibit is help with symptoms of depression, but it

0:06:03.760 --> 0:06:05.719
<v Speaker 3>takes a while for them to kick in. We know

0:06:05.800 --> 0:06:08.640
<v Speaker 3>the SSRI kind of hasn't action at the sign aps

0:06:08.640 --> 0:06:12.320
<v Speaker 3>to increase serotonin quite quickly, but your depression symptoms take

0:06:12.320 --> 0:06:14.440
<v Speaker 3>a really long time to maybe three weeks to sort

0:06:14.440 --> 0:06:17.360
<v Speaker 3>of start to resolve. What we think happens is this

0:06:17.400 --> 0:06:20.359
<v Speaker 3>is this cool kind of idea that's been tested, is

0:06:20.400 --> 0:06:24.200
<v Speaker 3>that when the serotonin levels go up, it changes your perception,

0:06:24.320 --> 0:06:27.880
<v Speaker 3>particularly your social interactions and perceptions of other people. So

0:06:27.920 --> 0:06:30.400
<v Speaker 3>someone with depression may walk past someone in a hallway

0:06:30.480 --> 0:06:32.000
<v Speaker 3>and that person might look at them or not, and

0:06:32.000 --> 0:06:33.480
<v Speaker 3>then they go, oh my god, they hate me. They're

0:06:33.520 --> 0:06:35.600
<v Speaker 3>not looking at the world through rose tinted glasses. It's

0:06:35.600 --> 0:06:39.680
<v Speaker 3>almost the opposite. So they just have these repeated bad experiences,

0:06:39.720 --> 0:06:43.039
<v Speaker 3>which feeds into their depressed state. As soon as you

0:06:43.080 --> 0:06:45.719
<v Speaker 3>take an SSRI, you start to perceive other people's social

0:06:45.720 --> 0:06:48.480
<v Speaker 3>interactions in a much more positive light. So you then

0:06:48.600 --> 0:06:51.279
<v Speaker 3>have to go through this sort of weeks of having

0:06:51.320 --> 0:06:55.800
<v Speaker 3>repeated positive interactions with other people. It's almost like your

0:06:55.800 --> 0:06:58.320
<v Speaker 3>brain needs to learn that actually, the world isn't.

0:06:58.240 --> 0:07:00.960
<v Speaker 2>Isn't as a safe isn't this terrible.

0:07:00.600 --> 0:07:03.680
<v Speaker 3>Doom and gloomy place where no one likes you. It's

0:07:03.720 --> 0:07:05.839
<v Speaker 3>almost like you put on the rose tined to glasses,

0:07:05.839 --> 0:07:06.720
<v Speaker 3>but then you have to live in.

0:07:06.600 --> 0:07:08.479
<v Speaker 2>That world for a little while. You have to.

0:07:08.800 --> 0:07:12.200
<v Speaker 3>So there's lots of things that we are learning about

0:07:12.320 --> 0:07:15.720
<v Speaker 3>how the brain reacts and responds to psychoactive substances that

0:07:16.080 --> 0:07:18.640
<v Speaker 3>may act in ways that we don't yet quite understand,

0:07:18.840 --> 0:07:21.000
<v Speaker 3>even though we may know that they work. And the

0:07:21.040 --> 0:07:22.840
<v Speaker 3>thing is, I always say they will work for some

0:07:22.840 --> 0:07:24.960
<v Speaker 3>people some of the time, not everyone all the time.

0:07:25.120 --> 0:07:26.840
<v Speaker 3>We need to be very very careful not to rule

0:07:26.920 --> 0:07:28.520
<v Speaker 3>something in or out because it worked for me or it.

0:07:28.440 --> 0:07:30.240
<v Speaker 2>Didn't work for you.

0:07:30.560 --> 0:07:45.840
<v Speaker 1>So interesting, why is it so hard to get real

0:07:45.880 --> 0:07:49.080
<v Speaker 1>answers about your health. If you've been told that everything

0:07:49.200 --> 0:07:52.040
<v Speaker 1>looks fine, but you know that something is off, you're

0:07:52.080 --> 0:07:55.600
<v Speaker 1>not imagining it. That's why I created Vitality three point

0:07:55.600 --> 0:07:58.920
<v Speaker 1>sixty to help you better understand what's going on inside

0:07:58.920 --> 0:08:02.120
<v Speaker 1>your body so that you can take the targeted action needed.

0:08:02.320 --> 0:08:05.800
<v Speaker 1>With a functional health approach plus testing, we go beyond

0:08:05.920 --> 0:08:09.440
<v Speaker 1>the guesswork to uncover the root causes of your symptoms.

0:08:09.680 --> 0:08:13.640
<v Speaker 1>I've teamed up with Doctasmina, an incredible integrative GP, and

0:08:13.680 --> 0:08:16.840
<v Speaker 1>together we will help you decode your body's signals and

0:08:16.920 --> 0:08:21.000
<v Speaker 1>answer questions like why am I always exhausted? What's really

0:08:21.040 --> 0:08:25.080
<v Speaker 1>causing my stubborn weight? Am I inflamed? Insulin resistant? Or

0:08:25.120 --> 0:08:28.960
<v Speaker 1>maybe missing key nutrients? Because when you understand your body better,

0:08:29.200 --> 0:08:30.720
<v Speaker 1>you can transform your health.

0:08:30.880 --> 0:08:33.360
<v Speaker 2>Visit v three sixty dot health or check out the

0:08:33.360 --> 0:08:34.280
<v Speaker 2>show notes for more.

0:08:44.040 --> 0:08:46.760
<v Speaker 1>All right, I want to ask you about peptides and

0:08:47.640 --> 0:08:50.640
<v Speaker 1>I know there, I just I wish my listeners could

0:08:50.640 --> 0:08:52.400
<v Speaker 1>see the look on your face when I just said

0:08:52.400 --> 0:08:55.840
<v Speaker 1>that word. But the petties are being marketed to the

0:08:55.840 --> 0:08:59.440
<v Speaker 1>biohackers wanting to you know, hack They wait longevity and

0:08:59.720 --> 0:09:02.520
<v Speaker 1>I have to say personally, I've got big concerns about

0:09:02.520 --> 0:09:05.080
<v Speaker 1>the reach that they are gaining in such a short

0:09:05.120 --> 0:09:09.480
<v Speaker 1>space of time, given their minimal efficacy, their minimal FDA

0:09:09.640 --> 0:09:12.960
<v Speaker 1>TGA approval, and lack of clinical trials. But I still

0:09:12.960 --> 0:09:15.640
<v Speaker 1>want to check in with you as to whether you

0:09:15.679 --> 0:09:19.760
<v Speaker 1>are particularly excited about any of the ones being discussed

0:09:19.800 --> 0:09:22.439
<v Speaker 1>from a brain health perspective. I want to see maybe

0:09:22.440 --> 0:09:24.600
<v Speaker 1>you've got a different take and you think there's some

0:09:24.720 --> 0:09:27.160
<v Speaker 1>promising sides out there.

0:09:27.240 --> 0:09:29.560
<v Speaker 3>I haven't seen any of the marketing that's going on

0:09:29.559 --> 0:09:30.600
<v Speaker 3>on social media.

0:09:31.200 --> 0:09:33.319
<v Speaker 2>You've not been fed yet. Wait till you start looking.

0:09:33.440 --> 0:09:34.800
<v Speaker 2>Just start typing my phone.

0:09:35.000 --> 0:09:37.640
<v Speaker 3>My phone's on airplane mode right now, so it's not

0:09:37.720 --> 0:09:40.160
<v Speaker 3>going to listen. It's not hearing this conversation.

0:09:40.240 --> 0:09:41.760
<v Speaker 2>Yeah, okay, it'll be interesting now.

0:09:41.840 --> 0:09:43.480
<v Speaker 3>I haven't been fitting you of this. I was asking

0:09:43.480 --> 0:09:45.280
<v Speaker 3>my personal trainer this morning at the gym, I see

0:09:45.440 --> 0:09:47.640
<v Speaker 3>you sort of. She's like, oh, yeah, last couple of months,

0:09:47.640 --> 0:09:50.199
<v Speaker 3>it's all I get, which is interesting. I mean, the

0:09:50.280 --> 0:09:51.880
<v Speaker 3>TGA has just come out in the last few weeks

0:09:51.920 --> 0:09:54.600
<v Speaker 3>here in Australia. Warned like, just be careful because you're like,

0:09:54.760 --> 0:09:57.760
<v Speaker 3>maybe you're importing these from China, and you're injecting them

0:09:57.800 --> 0:10:00.679
<v Speaker 3>into you. I mean, people aren't wanting to take a

0:10:01.520 --> 0:10:05.600
<v Speaker 3>vaccine or take the oral contraceptive pearl or take I

0:10:05.640 --> 0:10:07.920
<v Speaker 3>don't know something that's well studying and has got a

0:10:07.960 --> 0:10:10.280
<v Speaker 3>really great risk profile, but they are and they'll inject

0:10:10.360 --> 0:10:11.479
<v Speaker 3>something else because.

0:10:11.200 --> 0:10:14.120
<v Speaker 2>Some bro has promised, has promised.

0:10:16.040 --> 0:10:17.640
<v Speaker 3>I don't like to call them brows. Actually, I prefer

0:10:17.679 --> 0:10:20.120
<v Speaker 3>to call them ice bath boys and put them back

0:10:20.120 --> 0:10:22.720
<v Speaker 3>in the little place where they kind of struggled them along.

0:10:23.000 --> 0:10:26.400
<v Speaker 3>It's just this crazy, wide, wide wild west out there.

0:10:26.640 --> 0:10:29.480
<v Speaker 3>I'm quite conservative, and I'm also not a doctor. I

0:10:29.520 --> 0:10:32.120
<v Speaker 3>don't treat people. So you know, what would the clinical

0:10:32.160 --> 0:10:34.800
<v Speaker 3>practice guideline say? What does the TGA say? No way

0:10:34.840 --> 0:10:37.800
<v Speaker 3>would I be doing anything like that. That's not to

0:10:37.840 --> 0:10:40.760
<v Speaker 3>say peptides per se are just like kind of chains

0:10:40.760 --> 0:10:43.320
<v Speaker 3>of amino acids, and we've got them already in our body.

0:10:43.400 --> 0:10:46.440
<v Speaker 3>GLP ones are a type of pep tide. We've got

0:10:46.480 --> 0:10:49.120
<v Speaker 3>signaling molecules in our body. But like you kind of

0:10:49.160 --> 0:10:54.079
<v Speaker 3>tweak one molecule, you know, this massive cascade because everything's

0:10:54.080 --> 0:10:57.440
<v Speaker 3>in this kind of internal feedback loop, So we don't

0:10:57.480 --> 0:10:59.880
<v Speaker 3>know what we're doing when we're putting these into ourselves,

0:11:00.040 --> 0:11:02.360
<v Speaker 3>and I wouldn't be taking any of them. A lot

0:11:02.400 --> 0:11:04.480
<v Speaker 3>of them have got evidence, like rats and mice, right,

0:11:04.559 --> 0:11:07.520
<v Speaker 3>and then you go into you know, a small trial

0:11:07.600 --> 0:11:09.920
<v Speaker 3>and humans you might see some benefits. You go into

0:11:09.920 --> 0:11:11.800
<v Speaker 3>a full randomized.

0:11:11.559 --> 0:11:14.520
<v Speaker 1>And many of them don't even have haven't even made

0:11:14.559 --> 0:11:16.280
<v Speaker 1>it that far. I thought that's what you're going to say,

0:11:16.280 --> 0:11:18.160
<v Speaker 1>but I did just want to check in case there

0:11:18.240 --> 0:11:19.640
<v Speaker 1>was some amazing one that.

0:11:19.840 --> 0:11:22.079
<v Speaker 2>Just take some coffee.

0:11:22.200 --> 0:11:24.360
<v Speaker 1>I got. This is my next question to laugh and

0:11:24.400 --> 0:11:26.000
<v Speaker 1>I want to We're going to I'm going to do

0:11:26.000 --> 0:11:27.960
<v Speaker 1>a bit of a rapid fire because I'm like, if

0:11:28.000 --> 0:11:31.640
<v Speaker 1>not peptides to give us a mental edge, then what

0:11:31.800 --> 0:11:34.800
<v Speaker 1>else can we do to give our brains that short

0:11:34.880 --> 0:11:36.240
<v Speaker 1>term edge that's safe?

0:11:36.280 --> 0:11:38.800
<v Speaker 2>And so yeah, my first one was coffee.

0:11:38.440 --> 0:11:40.960
<v Speaker 3>Or coffee, yes, okay, three or four cups a day. Yeah,

0:11:41.000 --> 0:11:43.200
<v Speaker 3>as long as it's not disrupting your sleep. There is

0:11:43.320 --> 0:11:45.600
<v Speaker 3>no evidence that it's going to be bad for you.

0:11:45.679 --> 0:11:48.360
<v Speaker 3>There's so much evidence it would fill us room that

0:11:48.400 --> 0:11:49.160
<v Speaker 3>it's good for your brain.

0:11:49.240 --> 0:11:51.559
<v Speaker 1>Yep, okay, great, yeah, Oh my gosh, my listeners are

0:11:51.679 --> 0:11:54.200
<v Speaker 1>just high fiving you right now. What about a mega

0:11:54.240 --> 0:11:55.920
<v Speaker 1>three supplementation.

0:11:55.720 --> 0:11:57.360
<v Speaker 3>And two minds about that. I think if you're not

0:11:57.440 --> 0:11:59.760
<v Speaker 3>eating the whole fish, you're better off gone and a

0:11:59.800 --> 0:12:01.760
<v Speaker 3>piece of salmon. Not everyone can afford to do that.

0:12:01.960 --> 0:12:03.360
<v Speaker 3>You're better off eating the whole food.

0:12:03.480 --> 0:12:06.439
<v Speaker 2>But if you had not an oily fish kind of gowl, yeah.

0:12:06.480 --> 0:12:10.560
<v Speaker 3>Like I think, you know, maybe yeah, yeah, okay, but

0:12:10.600 --> 0:12:12.520
<v Speaker 3>it's probably not going to do you any harm. But

0:12:12.559 --> 0:12:14.080
<v Speaker 3>you'd be better off eating whole foods.

0:12:14.160 --> 0:12:16.000
<v Speaker 2>Okay. What about creatine?

0:12:16.280 --> 0:12:19.560
<v Speaker 3>Oh gosh, Minefield. I was like, I got AI should

0:12:19.600 --> 0:12:22.439
<v Speaker 3>design chat you be teacher to design me a pot

0:12:22.480 --> 0:12:24.720
<v Speaker 3>of creative. If I was to sell like Pink Creating

0:12:25.040 --> 0:12:27.480
<v Speaker 3>fog Off, I was going to call it like doctor

0:12:27.520 --> 0:12:33.120
<v Speaker 3>Sarah and fog Off creatine for metopause women, and please,

0:12:33.360 --> 0:12:36.360
<v Speaker 3>I will make millions if I had the gumption to

0:12:36.440 --> 0:12:41.280
<v Speaker 3>do it. I take creatine. I started taking creating. There's

0:12:41.440 --> 0:12:43.719
<v Speaker 3>a tiny bit of data. I know that there was

0:12:43.760 --> 0:12:45.600
<v Speaker 3>a clinical trial that was going to be started up

0:12:45.640 --> 0:12:47.920
<v Speaker 3>recently and it had gone through ethical approve. It was

0:12:47.920 --> 0:12:50.680
<v Speaker 3>actually here in Sydney. But then the data came in

0:12:50.960 --> 0:12:53.319
<v Speaker 3>saying that the dose wasn't going to be big enough.

0:12:53.360 --> 0:12:54.840
<v Speaker 3>And I had gone through all of the ethical approove

0:12:54.880 --> 0:12:56.839
<v Speaker 3>life and there's a whole PhD students project on it

0:12:57.200 --> 0:12:58.840
<v Speaker 3>and that and they were like, actually, the dose isn't

0:12:58.840 --> 0:13:00.680
<v Speaker 3>going to be quite enough to touch the sides to

0:13:00.679 --> 0:13:03.040
<v Speaker 3>see benefits. If we're going to see it, we need

0:13:03.080 --> 0:13:05.439
<v Speaker 3>to see increased levels in the brain.

0:13:05.240 --> 0:13:08.520
<v Speaker 1>Which is what around the ten grander something like, because

0:13:08.559 --> 0:13:12.640
<v Speaker 1>I think traditionally it's for muscle and performances.

0:13:12.120 --> 0:13:14.599
<v Speaker 3>Five and it's pretty well established for building muscle, like

0:13:14.640 --> 0:13:16.440
<v Speaker 3>you've got to be listing the weights and it will

0:13:16.480 --> 0:13:20.280
<v Speaker 3>help with that. The really interesting story is around particularly

0:13:20.280 --> 0:13:22.319
<v Speaker 3>midlife brain fog, when we're talking about that reduction in

0:13:22.360 --> 0:13:25.040
<v Speaker 3>the metabolism and the reduction and the efficiency of neurons

0:13:25.080 --> 0:13:28.920
<v Speaker 3>turning glucose into energy, and that's like partly hormonally driven

0:13:29.000 --> 0:13:32.079
<v Speaker 3>like that, like the hormones kind of help the neurons

0:13:32.200 --> 0:13:34.960
<v Speaker 3>use glucose, and the insulin does that and the rest

0:13:35.000 --> 0:13:36.560
<v Speaker 3>of in the other cells in your body, but in

0:13:36.559 --> 0:13:39.600
<v Speaker 3>your brain, estrogen kind of helps manage that processing. Can

0:13:39.760 --> 0:13:43.839
<v Speaker 3>creatine kind of side step that you know where you're

0:13:43.840 --> 0:13:47.400
<v Speaker 3>going through that kind of adaptation through perimenopause. That's kind

0:13:47.400 --> 0:13:49.160
<v Speaker 3>of the question, and there is a little bit of

0:13:49.160 --> 0:13:54.320
<v Speaker 3>evidence out there in some teeny tiny trials, saying perhaps.

0:13:54.720 --> 0:13:58.440
<v Speaker 1>My argument is take it for six to eight weeks

0:13:59.320 --> 0:14:00.880
<v Speaker 1>and see if you notice a difference.

0:14:01.000 --> 0:14:03.160
<v Speaker 3>Yeah, but it's hard, you know then like you don't

0:14:03.160 --> 0:14:05.240
<v Speaker 3>know whether efforts for yourself it's a placebo or not.

0:14:05.280 --> 0:14:07.280
<v Speaker 3>And that's always my thing, because you can convince yourself

0:14:07.280 --> 0:14:07.720
<v Speaker 3>of any.

0:14:07.760 --> 0:14:08.520
<v Speaker 2>True you could.

0:14:08.920 --> 0:14:11.280
<v Speaker 3>You could take flour and water and like say this

0:14:11.320 --> 0:14:12.240
<v Speaker 3>is going to make me feel.

0:14:12.080 --> 0:14:14.640
<v Speaker 2>Yeah, no, I would much get to have the clinical trials.

0:14:14.679 --> 0:14:16.680
<v Speaker 3>But like so I think that there's probably not going

0:14:16.760 --> 0:14:19.160
<v Speaker 3>to be harm done unless you've gotkidney disease. Yeah, because

0:14:19.160 --> 0:14:21.960
<v Speaker 3>people are like every teenage boy on all the beaches

0:14:22.040 --> 0:14:24.800
<v Speaker 3>is smashing back the creuse. I can't even get it

0:14:24.840 --> 0:14:26.880
<v Speaker 3>at the supermarts out, So.

0:14:27.520 --> 0:14:31.280
<v Speaker 1>Okay, but interesting, there's nothing that you're taking it I'm taking.

0:14:31.280 --> 0:14:33.520
<v Speaker 1>I feel like I noticed a difference when I started

0:14:33.560 --> 0:14:36.120
<v Speaker 1>taking it in both performance in the gym. I'm a

0:14:36.120 --> 0:14:38.320
<v Speaker 1>bit of a good lab rap because I'm so consistent.

0:14:38.360 --> 0:14:41.600
<v Speaker 1>And yes, it could be placebo, but I notice absolutely

0:14:41.640 --> 0:14:43.560
<v Speaker 1>in the gym, like I know when I'm doing you know,

0:14:43.600 --> 0:14:45.480
<v Speaker 1>when I get to about six berpes in a row,

0:14:46.080 --> 0:14:48.920
<v Speaker 1>I will feel my body like I will physically feel

0:14:48.920 --> 0:14:50.520
<v Speaker 1>myself slowing down, and I was getting to more like

0:14:50.600 --> 0:14:53.600
<v Speaker 1>nine or ten interesting, and that was definitely not placebo.

0:14:53.800 --> 0:14:56.280
<v Speaker 1>But then in my in my focus, I noticed a

0:14:56.320 --> 0:14:57.360
<v Speaker 1>difference as well.

0:14:57.160 --> 0:14:59.840
<v Speaker 3>Because I've got a wild imagination, so I can placebo

0:14:59.880 --> 0:15:02.200
<v Speaker 3>on no Cea by myself super easily. I ended up

0:15:02.240 --> 0:15:05.600
<v Speaker 3>in neurologist having an MRI a few years ago because

0:15:05.640 --> 0:15:07.880
<v Speaker 3>I had been dizzy for weeks and week all months,

0:15:08.080 --> 0:15:10.400
<v Speaker 3>like six months, and it turned out I was just

0:15:10.440 --> 0:15:12.720
<v Speaker 3>quite streets. And he said, some people get insomnia, some

0:15:12.720 --> 0:15:15.840
<v Speaker 3>people get hit apes. He said, you've just got dizzy.

0:15:15.960 --> 0:15:18.240
<v Speaker 3>And he said tomorrow, next time, when you get dizzy,

0:15:18.280 --> 0:15:20.040
<v Speaker 3>just kind of go oh whatever, I'm just dizzy. And

0:15:20.040 --> 0:15:22.040
<v Speaker 3>then he said, and then just start spelling words backwards.

0:15:22.440 --> 0:15:23.560
<v Speaker 3>I was better with him one day.

0:15:23.680 --> 0:15:26.240
<v Speaker 2>Oh my goodness, I had like the sea bowed myself.

0:15:26.400 --> 0:15:29.880
<v Speaker 3>I love that I'm personally weary because I can convince

0:15:29.920 --> 0:15:33.800
<v Speaker 3>myself or of all sorts of things. Either way, I

0:15:33.800 --> 0:15:36.080
<v Speaker 3>would not tell anyone else to take creatine because I've

0:15:36.120 --> 0:15:37.720
<v Speaker 3>said I'm taking it, or I think it's good for

0:15:37.760 --> 0:15:38.840
<v Speaker 3>your brain, but.

0:15:38.840 --> 0:15:40.800
<v Speaker 2>I'm taking Yeah, you are taking all right.

0:15:40.840 --> 0:15:43.320
<v Speaker 3>I might start marketing fog off one day so I

0:15:43.400 --> 0:15:45.040
<v Speaker 3>might go and try the space.

0:15:45.120 --> 0:15:47.080
<v Speaker 2>We'll get you back on for that. All right, so short,

0:15:47.120 --> 0:15:47.360
<v Speaker 2>too many.

0:15:47.480 --> 0:15:50.680
<v Speaker 1>We've got caffeine, we've potentially got a Mega three's, we've

0:15:50.720 --> 0:15:53.120
<v Speaker 1>potentially got creatine. Is there anything else to give our

0:15:53.160 --> 0:15:54.560
<v Speaker 1>brains a bit of an edge?

0:15:54.240 --> 0:15:55.480
<v Speaker 2>Like sleep?

0:15:55.600 --> 0:15:56.920
<v Speaker 1>Ah? Love it?

0:15:57.040 --> 0:16:01.160
<v Speaker 3>Sorry? You know, like a good laugh? Honestly, I feel

0:16:01.200 --> 0:16:05.640
<v Speaker 3>like we forget about just enjoying ourselves and just find

0:16:05.680 --> 0:16:09.040
<v Speaker 3>some funny friends. Oh, I just like hang out with them.

0:16:09.480 --> 0:16:12.400
<v Speaker 2>Oh, I love it laughing the best medicine. Doctor Sarah,

0:16:12.480 --> 0:16:13.200
<v Speaker 2>Thank you so much.

0:16:13.680 --> 0:16:14.360
<v Speaker 3>You're so welcome.

0:16:32.760 --> 0:16:35.240
<v Speaker 1>Why is it so hard to get real answers about

0:16:35.240 --> 0:16:38.600
<v Speaker 1>your health? If you've been told that everything looks fine,

0:16:38.800 --> 0:16:41.720
<v Speaker 1>but you know that something is off, you're not imagining it.

0:16:41.920 --> 0:16:45.120
<v Speaker 1>That's why I created Vitality three point sixty to help

0:16:45.160 --> 0:16:48.360
<v Speaker 1>you better understand what's going on inside your body so

0:16:48.400 --> 0:16:51.240
<v Speaker 1>that you can take the targeted action needed. With a

0:16:51.240 --> 0:16:55.400
<v Speaker 1>functional health approach plus testing, we go beyond the guesswork

0:16:55.520 --> 0:16:58.880
<v Speaker 1>to uncover the root causes of your symptoms. I've teamed

0:16:58.920 --> 0:17:02.760
<v Speaker 1>up with doctor Esmina, an incredible integrative GP, and together

0:17:02.840 --> 0:17:05.919
<v Speaker 1>we will help you decode your body's signals and answer

0:17:06.000 --> 0:17:10.040
<v Speaker 1>questions like why am I always exhausted? What's really causing

0:17:10.080 --> 0:17:14.200
<v Speaker 1>my stubborn weight? Am I inflamed, insulin resistant? Or maybe

0:17:14.200 --> 0:17:17.600
<v Speaker 1>missing key nutrients. Because when you understand your body better,

0:17:17.840 --> 0:17:20.960
<v Speaker 1>you can transform your health. Visit V three sixty dot

0:17:21.040 --> 0:17:22.960
<v Speaker 1>Health or check out the show notes for more