1 00:00:00,080 --> 00:00:03,640 Speaker 1: In the mitochondrias all from mom, so you get your 2 00:00:03,720 --> 00:00:07,640 Speaker 1: mother's bio energetic genes. This is why we get so 3 00:00:07,760 --> 00:00:13,480 Speaker 1: much autism with each generation, because moms are not healthy anymore. 4 00:00:24,840 --> 00:00:25,280 Speaker 2: Everyone. 5 00:00:25,680 --> 00:00:27,520 Speaker 3: Before we get into this week's podcast, we got a 6 00:00:27,560 --> 00:00:31,640 Speaker 3: pretty cool announcement to make you are not able to 7 00:00:32,000 --> 00:00:35,000 Speaker 3: connect with us. We have a pretty cool little widget 8 00:00:35,000 --> 00:00:38,200 Speaker 3: that's on the website. Just go to poletailor dot biz 9 00:00:38,840 --> 00:00:42,160 Speaker 3: Forwards Slash Podcast and near the top of the page 10 00:00:42,200 --> 00:00:45,320 Speaker 3: you'll see a little icon that says send a message 11 00:00:45,360 --> 00:00:48,559 Speaker 3: to the Paul Taylor Podcast. 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So looking forward to hearing from 29 00:01:35,959 --> 00:01:38,080 Speaker 3: you now I hover the podcast. 30 00:01:38,640 --> 00:01:42,280 Speaker 4: Hey, everybody, welcome to part two of the podcast with Christa. 31 00:01:42,040 --> 00:01:46,319 Speaker 5: Bell, where we explore the magic of your mitochondria and 32 00:01:46,360 --> 00:01:50,320 Speaker 5: a little bit more detail and importantly get to actionable 33 00:01:50,400 --> 00:01:54,760 Speaker 5: strategies that everybody can do to improve their mitochondrial function 34 00:01:54,920 --> 00:01:58,559 Speaker 5: and therefore their overall physical and mental health. 35 00:01:59,160 --> 00:02:02,760 Speaker 4: Enjoy going to get pretty complicated here because we're going. 36 00:02:02,680 --> 00:02:04,240 Speaker 2: To talk about complex four. 37 00:02:04,280 --> 00:02:09,040 Speaker 4: We're going to talk about critosome seoxides, But listeners just 38 00:02:09,320 --> 00:02:10,440 Speaker 4: hang with us here. 39 00:02:10,800 --> 00:02:12,840 Speaker 2: This will get a little bit technical. 40 00:02:13,639 --> 00:02:17,640 Speaker 4: But for me, I mean I've only really dug into 41 00:02:17,919 --> 00:02:21,960 Speaker 4: the impact of light, red light and particularly near infra 42 00:02:22,040 --> 00:02:26,240 Speaker 4: red light on our health and particularly mitochondria in the 43 00:02:26,360 --> 00:02:27,800 Speaker 4: last couple of years. 44 00:02:28,400 --> 00:02:29,000 Speaker 2: Talk to our. 45 00:02:28,919 --> 00:02:32,720 Speaker 4: Listeners through this because it's pretty freaking fascinating. 46 00:02:33,320 --> 00:02:36,799 Speaker 1: Well, I think you're probably going to tell us more 47 00:02:37,480 --> 00:02:41,320 Speaker 1: than what I can tell you, Paul, because I'm not 48 00:02:41,720 --> 00:02:45,800 Speaker 1: across all of the light spectral frequencies that do the 49 00:02:45,840 --> 00:02:49,320 Speaker 1: different things in the cyt currency of todays and so on, 50 00:02:49,440 --> 00:02:53,880 Speaker 1: I usually refer to my good friend and colleague Nathan Styles. 51 00:02:53,919 --> 00:02:58,040 Speaker 1: Have you heard him speak? So he is my light light, 52 00:02:58,200 --> 00:03:02,000 Speaker 1: my spectral light frequency, and I've got all his slides 53 00:03:02,040 --> 00:03:07,080 Speaker 1: and all the different amazing frequencies that trigger everything across 54 00:03:07,560 --> 00:03:11,040 Speaker 1: the sun, all the light frequencies as the sun moves 55 00:03:11,080 --> 00:03:16,400 Speaker 1: across the sky. And nature is amazing because it's so specific, 56 00:03:16,560 --> 00:03:20,240 Speaker 1: Like every single frequency has got a receptor in our 57 00:03:20,280 --> 00:03:25,680 Speaker 1: body across different protein receptor sites, hormones, they look like 58 00:03:25,760 --> 00:03:30,040 Speaker 1: certain nutrients. They trigger these pathways that pathways. You can 59 00:03:30,400 --> 00:03:34,720 Speaker 1: bring it down all to which light frequency as to 60 00:03:34,920 --> 00:03:39,360 Speaker 1: what metabolic pathways you want to trigger. So I don't 61 00:03:39,400 --> 00:03:41,840 Speaker 1: have all the numbers and the receptors and things in 62 00:03:41,840 --> 00:03:44,200 Speaker 1: my head. I just know that we need to be 63 00:03:44,320 --> 00:03:47,280 Speaker 1: exposed to the light across the whole spectrum. 64 00:03:47,520 --> 00:03:49,320 Speaker 2: Yeah, I'm professor kront school. Thing. 65 00:03:49,560 --> 00:03:53,640 Speaker 4: He sent me a paper that just blew my mind 66 00:03:54,360 --> 00:04:01,240 Speaker 4: that shows that light actually has quantum effects on ourselves. Right, 67 00:04:01,320 --> 00:04:05,320 Speaker 4: so we know it stimulates the mitochondria, does lots. You know, 68 00:04:05,400 --> 00:04:08,880 Speaker 4: vitamin D. Everybody knows Sunlight's really important. But as you say, 69 00:04:08,920 --> 00:04:13,920 Speaker 4: the different colors are different frequencies in light. We now 70 00:04:13,920 --> 00:04:17,520 Speaker 4: I know that red lights, I think it's like sticks 71 00:04:17,600 --> 00:04:21,000 Speaker 4: under the seven seven point fifty is really good for 72 00:04:21,120 --> 00:04:25,560 Speaker 4: the skin. And then the near infra red stuff actually 73 00:04:25,640 --> 00:04:30,960 Speaker 4: penetrates the skin and stimulates the mitochondria, and particularly I 74 00:04:30,960 --> 00:04:35,640 Speaker 4: think it's complex for the mitochondria, gets the mitochondria to 75 00:04:35,680 --> 00:04:41,040 Speaker 4: then release nitric oxide, helps with the respiratory chine antiox 76 00:04:41,080 --> 00:04:44,840 Speaker 4: and anti inflammatory. Like, it's crazy. Shit, what light can 77 00:04:44,880 --> 00:04:45,760 Speaker 4: do in the body. 78 00:04:45,560 --> 00:04:48,240 Speaker 1: Is It is crazy. It's a different color for each 79 00:04:48,320 --> 00:04:51,599 Speaker 1: of the electron transport chains, and. 80 00:04:51,960 --> 00:04:53,960 Speaker 2: I never thought about it like that. 81 00:04:54,160 --> 00:04:57,880 Speaker 1: Okay, so it's I just wanted to laugh when you 82 00:04:57,920 --> 00:05:01,360 Speaker 1: said about the red light with skin because I've been 83 00:05:01,360 --> 00:05:04,440 Speaker 1: watching this. I mean I've been look I've been into 84 00:05:04,520 --> 00:05:09,480 Speaker 1: light for about ten years and looking at Michael Webber's 85 00:05:09,880 --> 00:05:13,960 Speaker 1: light treatments. We do intravenous light therapy the light. Intravenous 86 00:05:14,000 --> 00:05:16,720 Speaker 1: light therapy goes across all the spectrums of the colors 87 00:05:16,720 --> 00:05:19,359 Speaker 1: of the light to feed the CREB cycle, the different 88 00:05:19,360 --> 00:05:22,120 Speaker 1: electron transport chain stuff like that. It's anyway, it's all 89 00:05:22,440 --> 00:05:24,960 Speaker 1: good fun. The Germans have been looking at it for ages, 90 00:05:25,200 --> 00:05:28,120 Speaker 1: you know, Michael Webber, and we've been looking at it 91 00:05:28,160 --> 00:05:31,640 Speaker 1: with complex conditions, neological diseases. How do you solve all 92 00:05:31,720 --> 00:05:33,120 Speaker 1: these difficult problems? 93 00:05:33,600 --> 00:05:36,520 Speaker 6: But I love it that it's the skin that everyone 94 00:05:36,640 --> 00:05:39,000 Speaker 6: is suddenly Wow, did you know red light's so good? 95 00:05:39,040 --> 00:05:41,719 Speaker 1: Because you look your skin looks so good? Like, yes, 96 00:05:42,200 --> 00:05:44,600 Speaker 1: I should have started with the skin in the first place, 97 00:05:44,760 --> 00:05:48,560 Speaker 1: not all these difficult unseen things. But anyway, that all 98 00:05:48,560 --> 00:05:52,039 Speaker 1: the different colors, all the different spectral frequencies, even in 99 00:05:52,120 --> 00:05:56,080 Speaker 1: each band of color, speaks even more deeply, not just 100 00:05:56,080 --> 00:05:59,640 Speaker 1: the mitochondria and energy, but also to different receptor sites 101 00:05:59,680 --> 00:06:03,120 Speaker 1: a US saying in our cells, our hormones, all these 102 00:06:03,160 --> 00:06:07,040 Speaker 1: different metabolic pathways. And the other week I was reading 103 00:06:07,080 --> 00:06:10,960 Speaker 1: this amazing paper. It's I think it's already two or 104 00:06:11,000 --> 00:06:15,200 Speaker 1: three years old. They're talking about optogenetic light switches. So 105 00:06:15,200 --> 00:06:20,280 Speaker 1: they're studying different light frequencies to switch on and switch 106 00:06:20,480 --> 00:06:27,640 Speaker 1: off mitochondrial light receptors, so optogenetic switches. So they're going 107 00:06:27,680 --> 00:06:31,200 Speaker 1: to find exactly the frequency to turn on your metabolism 108 00:06:31,360 --> 00:06:33,760 Speaker 1: so that you can burn that faster and do this 109 00:06:33,880 --> 00:06:38,040 Speaker 1: and do that better. Like I can't wait till that 110 00:06:38,360 --> 00:06:41,240 Speaker 1: comes out. But then I don't think Big Farmer is 111 00:06:41,279 --> 00:06:43,800 Speaker 1: going to be able to capture that one, you. 112 00:06:43,760 --> 00:06:48,480 Speaker 4: Know, genesis that really like it's there's depths to this, 113 00:06:49,080 --> 00:06:52,680 Speaker 4: Clearly there's levels to this, and yeah, some of the research, 114 00:06:52,760 --> 00:06:56,839 Speaker 4: but just understanding that the light can actually penetrate the 115 00:06:56,880 --> 00:07:01,680 Speaker 4: body and directly activate the mighty quandary is pretty amazing. 116 00:07:01,680 --> 00:07:03,719 Speaker 4: And as you said, hormones and all sorts of stuff, 117 00:07:03,760 --> 00:07:06,320 Speaker 4: and this is why it's important to get out into 118 00:07:06,360 --> 00:07:07,360 Speaker 4: the friggin sun. 119 00:07:07,760 --> 00:07:07,960 Speaker 2: Right. 120 00:07:08,200 --> 00:07:12,080 Speaker 4: I think we've gone too far in this country with 121 00:07:12,240 --> 00:07:15,280 Speaker 4: the slop slip. I always get that wrong slip stop slop, 122 00:07:15,320 --> 00:07:17,040 Speaker 4: slop stop slip, whatever it is. 123 00:07:17,080 --> 00:07:19,680 Speaker 2: But you know the fact that I think it's more 124 00:07:19,760 --> 00:07:22,000 Speaker 2: than thirty percent of austreamings. You might know the number 125 00:07:22,040 --> 00:07:23,240 Speaker 2: better than me, but a. 126 00:07:23,480 --> 00:07:28,560 Speaker 4: Vitamin D deficiency or insufficiency. I mean, it's comparable to 127 00:07:28,640 --> 00:07:33,480 Speaker 4: Bloody Scotland and Northern Highland for this justin fragginshy. But 128 00:07:33,520 --> 00:07:35,800 Speaker 4: people don't realize the imp it's not just strenam indeed, 129 00:07:35,960 --> 00:07:39,760 Speaker 4: but it's just the impact on hormones, in the impact 130 00:07:39,800 --> 00:07:43,040 Speaker 4: of mitochondria. With saying impacts on mood or metabolic heals 131 00:07:43,240 --> 00:07:44,560 Speaker 4: all of these things right. 132 00:07:44,960 --> 00:07:47,400 Speaker 1: Indeed, I mean that's been the big focus of a 133 00:07:47,400 --> 00:07:50,280 Speaker 1: lot of my misochondrial talks in the last several years, 134 00:07:50,360 --> 00:07:54,800 Speaker 1: is just get your light environment right as a starting point, 135 00:07:54,880 --> 00:07:57,040 Speaker 1: because also I think that it is a very good 136 00:07:57,680 --> 00:08:01,120 Speaker 1: opening point, you know how, and you do something maybe 137 00:08:01,120 --> 00:08:05,280 Speaker 1: more high up rather than top down. Then if you 138 00:08:05,360 --> 00:08:07,680 Speaker 1: get that, well you do something more top down rather 139 00:08:07,720 --> 00:08:10,720 Speaker 1: than bottom up. I'm meant, then that top down signal 140 00:08:10,840 --> 00:08:14,800 Speaker 1: can help a lot of levels below. And I think 141 00:08:14,920 --> 00:08:18,200 Speaker 1: I think that light is just that huge top down signal. 142 00:08:18,600 --> 00:08:20,560 Speaker 1: And I see that in my patients. I say to them, 143 00:08:20,600 --> 00:08:24,960 Speaker 1: look apart from the sunrise the sunset, go outside. I 144 00:08:25,000 --> 00:08:27,720 Speaker 1: say to people, please clock in through the day, literally 145 00:08:27,800 --> 00:08:31,240 Speaker 1: clock in. Get your eyes to see the sun. That 146 00:08:31,320 --> 00:08:34,920 Speaker 1: tells your brain, clock, your cicading rhythm, what time it is, 147 00:08:35,200 --> 00:08:38,280 Speaker 1: that sets up your metabolism and so on. But also 148 00:08:38,559 --> 00:08:41,280 Speaker 1: just you know that light going in through your eyes, 149 00:08:41,320 --> 00:08:43,800 Speaker 1: which is well your photo most of your photo receptors 150 00:08:43,840 --> 00:08:47,560 Speaker 1: are through your eyes. Chuck away your sunglasses. That's what 151 00:08:47,760 --> 00:08:51,600 Speaker 1: I hate seeing people wearing sunglasses and that body clock. 152 00:08:52,320 --> 00:08:54,200 Speaker 1: So what I was saying is, if we get the 153 00:08:54,280 --> 00:08:56,680 Speaker 1: light environment right, what I found I see in my 154 00:08:56,800 --> 00:09:00,800 Speaker 1: patients is they just naturally start to be able to 155 00:09:00,840 --> 00:09:03,520 Speaker 1: do the next thing I'm asking them to do. Start 156 00:09:03,559 --> 00:09:07,400 Speaker 1: to move, start to exercise. Oh, you're suddenly motivated to 157 00:09:07,440 --> 00:09:10,080 Speaker 1: get your diet better. Whereas before we like having to 158 00:09:10,640 --> 00:09:13,080 Speaker 1: hammer this thing. But if you can get some top 159 00:09:13,120 --> 00:09:17,640 Speaker 1: down signals right, and people just innately inside them feel 160 00:09:17,720 --> 00:09:22,240 Speaker 1: better because this whole sensory environment how I experience myself, 161 00:09:22,320 --> 00:09:25,200 Speaker 1: my body, my light, my space just feels better. It's like, 162 00:09:25,240 --> 00:09:27,079 Speaker 1: oh now I feel like doing this, Now I feel 163 00:09:27,080 --> 00:09:30,040 Speaker 1: like doing that. I found that things just unfold better. 164 00:09:30,120 --> 00:09:35,720 Speaker 1: So I always insist on the enlightened environment with my patients. 165 00:09:35,760 --> 00:09:38,360 Speaker 1: And then in my lectures, yes, I can go on 166 00:09:38,400 --> 00:09:41,080 Speaker 1: about mitochondria pathways, but in the end, can you just 167 00:09:41,120 --> 00:09:42,400 Speaker 1: go home and fix your lighting? 168 00:09:42,920 --> 00:09:45,160 Speaker 4: Yeah? Yeah, I never thought about it from a top 169 00:09:45,240 --> 00:09:48,080 Speaker 4: time perspective. Actually, that's a that's a really good point 170 00:09:48,120 --> 00:09:51,040 Speaker 4: at the fundamentals, right, and things flow. I need to 171 00:09:51,080 --> 00:09:54,040 Speaker 4: diet more into like I do want to talk about 172 00:09:54,559 --> 00:09:57,840 Speaker 4: because when you mentioned it, I'm like, oh, that sounds 173 00:09:57,840 --> 00:10:01,800 Speaker 4: pretty interesting my to con psychobiology. 174 00:10:02,200 --> 00:10:06,040 Speaker 1: Yes, let's talk about that. And then just with what 175 00:10:06,080 --> 00:10:09,280 Speaker 1: you just said, I was wanting to say that, Yeah, 176 00:10:09,520 --> 00:10:14,720 Speaker 1: that top down is really about how your brain feels 177 00:10:14,840 --> 00:10:17,520 Speaker 1: and senses the world that we live in. Let's go 178 00:10:17,600 --> 00:10:20,280 Speaker 1: out in nature, let's get the light. That's all a 179 00:10:20,440 --> 00:10:26,120 Speaker 1: very sensory, very lived experience. You can't read that in 180 00:10:26,120 --> 00:10:29,040 Speaker 1: a book, you can't just watch that on TV. Like. 181 00:10:29,080 --> 00:10:30,880 Speaker 1: You have to move it, you have to live it, 182 00:10:30,920 --> 00:10:32,679 Speaker 1: you have to smell it, you have to feel it. 183 00:10:33,440 --> 00:10:36,640 Speaker 1: And light is a sensory input. So the brain is 184 00:10:36,679 --> 00:10:39,640 Speaker 1: a sensory organ And just as you move your muscles 185 00:10:39,679 --> 00:10:44,080 Speaker 1: for plasticity of your muscles and mitobiogenesis of the mitochondria 186 00:10:44,080 --> 00:10:46,520 Speaker 1: in your muscles, you want to put a lot of 187 00:10:46,559 --> 00:10:51,040 Speaker 1: those inputs into your brain for that plasticity and experience 188 00:10:51,080 --> 00:10:53,280 Speaker 1: of your brain in the same way that you experience 189 00:10:53,280 --> 00:10:56,040 Speaker 1: your body and your muscles and the whole sensory motor 190 00:10:56,080 --> 00:11:00,680 Speaker 1: input through your postures and your actions and so on. So, right, 191 00:11:01,080 --> 00:11:05,360 Speaker 1: sound your thoughts, what people say to you, what you're 192 00:11:05,440 --> 00:11:08,679 Speaker 1: listening to. Is your TV on in the background, Is 193 00:11:08,800 --> 00:11:10,040 Speaker 1: CNN telling you. 194 00:11:10,200 --> 00:11:13,200 Speaker 2: All the awful negative shit? 195 00:11:13,440 --> 00:11:16,880 Speaker 4: Yeah, yeah, yeah, yeah, yeah, yeah, it's inputs, right, it's inputs. 196 00:11:17,240 --> 00:11:20,520 Speaker 1: Yeah. So sensory input, I think is a big part 197 00:11:20,679 --> 00:11:24,800 Speaker 1: of what you want to lead to, which is mitochondrial psychobiology. 198 00:11:25,400 --> 00:11:31,480 Speaker 1: So mitochondrial psychobiology is Martin Picard's lab. Martin Picard is 199 00:11:32,000 --> 00:11:37,440 Speaker 1: a wonderful mitochondrial researcher as well. He was Doug Wallace's 200 00:11:37,520 --> 00:11:42,800 Speaker 1: PhD student. Doug Wallace was the mitochondrial researcher that understood 201 00:11:42,800 --> 00:11:46,600 Speaker 1: that mitochondria will maternally inherited, so we get them purely 202 00:11:46,640 --> 00:11:47,640 Speaker 1: from our mothers. 203 00:11:47,960 --> 00:11:50,320 Speaker 4: Oh, that's right, I forgot about that. You said that 204 00:11:50,360 --> 00:11:54,120 Speaker 4: in your talk. It's mum that passes on the mitochondria, right, 205 00:11:54,160 --> 00:11:55,920 Speaker 4: because their genes are independent. 206 00:11:56,120 --> 00:11:59,480 Speaker 1: That's right. So you get well from the nuclear genetics 207 00:11:59,480 --> 00:12:03,240 Speaker 1: one from one from dad, but in the mitochondrids or 208 00:12:03,280 --> 00:12:06,800 Speaker 1: from mom, so you get your you get your mother's 209 00:12:07,200 --> 00:12:10,880 Speaker 1: bio energetic genes. And that's why it's very common to 210 00:12:10,920 --> 00:12:14,400 Speaker 1: see through family history it's the moms and the daughters 211 00:12:14,440 --> 00:12:17,720 Speaker 1: that have the chronic fatigue that have that the different 212 00:12:17,760 --> 00:12:21,360 Speaker 1: fatigue type syndromes. And then also I think that this 213 00:12:21,400 --> 00:12:23,480 Speaker 1: would be related that you know, this is why we 214 00:12:23,520 --> 00:12:28,280 Speaker 1: get so much autism with each generation because moms are 215 00:12:28,360 --> 00:12:33,240 Speaker 1: not healthy anymore and we're having babies older and older. 216 00:12:33,640 --> 00:12:37,560 Speaker 1: I get that that is a whole modern lifestyle decision. 217 00:12:38,240 --> 00:12:42,840 Speaker 1: But nature and modern lifestyles, that's your mismatch. That is 218 00:12:42,840 --> 00:12:47,520 Speaker 1: what Robert Navio talks about. It's a mitochondrial environmental mismatch. 219 00:12:48,200 --> 00:12:51,320 Speaker 1: One was through nature was doing this, but in modern 220 00:12:51,360 --> 00:12:54,920 Speaker 1: day we're doing that. And so that whole mismatch is that, 221 00:12:55,240 --> 00:12:58,320 Speaker 1: you know, we were supposed to probably have babies in 222 00:12:58,360 --> 00:13:01,959 Speaker 1: our teens and twenties when the mitochondrias are really young, 223 00:13:02,080 --> 00:13:05,240 Speaker 1: and don't have not young young, but you know, don't 224 00:13:05,240 --> 00:13:08,920 Speaker 1: have as much mutation and don't have as much heteroplasma 225 00:13:08,920 --> 00:13:14,199 Speaker 1: which I mentioned, which is simply environmental toxins and radiations 226 00:13:14,200 --> 00:13:18,280 Speaker 1: and the normal environmental stress which would normally mutate on 227 00:13:18,440 --> 00:13:23,640 Speaker 1: mitochondrial genes. That's normal, but the accumulation of it over 228 00:13:23,760 --> 00:13:28,319 Speaker 1: decades and then having a baby at forty that's stressful 229 00:13:28,360 --> 00:13:30,120 Speaker 1: for the next generation. 230 00:13:30,840 --> 00:13:34,000 Speaker 4: Interesting because there was some recent research that I read 231 00:13:34,040 --> 00:13:35,640 Speaker 4: I think I talked about in the podcast and I 232 00:13:35,679 --> 00:13:41,160 Speaker 4: can't remember the number, but maternal overWe it it's significantly 233 00:13:41,200 --> 00:13:45,840 Speaker 4: impacting upon autism spectrum disorders and other things like ADHD. 234 00:13:46,520 --> 00:13:49,640 Speaker 4: And that makes sense from what you just said, is 235 00:13:49,679 --> 00:13:51,560 Speaker 4: that especially. 236 00:13:51,080 --> 00:13:53,160 Speaker 2: You know, we have declining health. We are more and 237 00:13:53,200 --> 00:13:54,000 Speaker 2: more over weird. 238 00:13:54,120 --> 00:13:57,520 Speaker 4: But as you said, women are tending to have child 239 00:13:57,760 --> 00:14:01,760 Speaker 4: help children later. And then not only do you everybody 240 00:14:01,840 --> 00:14:04,640 Speaker 4: know who said it's a lot harder to states tram 241 00:14:04,720 --> 00:14:07,120 Speaker 4: and fit in your thirties and thirties and forties than 242 00:14:07,160 --> 00:14:09,640 Speaker 4: it is when you're in your teens and early twenties. 243 00:14:10,080 --> 00:14:13,240 Speaker 4: But I didn't think about the cumulative damage at a 244 00:14:13,280 --> 00:14:18,720 Speaker 4: cellular level and on the mitochondria. And presumably then there's 245 00:14:18,760 --> 00:14:23,360 Speaker 4: some sort of epigenetic effects from the mitoch It's not 246 00:14:23,440 --> 00:14:26,680 Speaker 4: just the genes that are going but an epigenetic effect 247 00:14:27,000 --> 00:14:28,760 Speaker 4: from the mitochondria perspective. 248 00:14:29,080 --> 00:14:35,440 Speaker 1: Yeah, so the epigenetic effect of our lifestyle, our artificial light, 249 00:14:35,720 --> 00:14:40,160 Speaker 1: blue light, toxic stress, you know, five G radiation, Those 250 00:14:40,160 --> 00:14:43,760 Speaker 1: are all the sorts of things that are stressful on genes. 251 00:14:44,400 --> 00:14:48,680 Speaker 1: So then when the mother's mitochondrial genes and epigenetics are 252 00:14:48,720 --> 00:14:50,920 Speaker 1: not that healthy and they're passing that all down to 253 00:14:50,960 --> 00:14:54,960 Speaker 1: the next generation, and what's happening to the generation after that, 254 00:14:54,960 --> 00:14:58,160 Speaker 1: that is the epigenetics going on in the mitochondria. And 255 00:14:58,240 --> 00:15:03,880 Speaker 1: that's why we're seeing more and more allergies, autism, add ADHD, 256 00:15:04,160 --> 00:15:08,880 Speaker 1: autoimmune So those are the five a's that in environmental 257 00:15:08,920 --> 00:15:11,760 Speaker 1: medicine we talk about a lot, and this is all 258 00:15:12,200 --> 00:15:16,080 Speaker 1: very well established, very well known in environmental medicine in 259 00:15:16,120 --> 00:15:19,960 Speaker 1: the last few decades. I'm just bringing the focus more 260 00:15:20,040 --> 00:15:24,400 Speaker 1: to it's the effect through the mitochondrial genetics too, because 261 00:15:24,720 --> 00:15:29,240 Speaker 1: when you've got heteroplasmi, which is when the mitochondrial genes mutate, 262 00:15:29,800 --> 00:15:33,120 Speaker 1: they can change back. They change and change back all 263 00:15:33,200 --> 00:15:37,600 Speaker 1: the time. They're very they're very plastic. So it's just 264 00:15:37,920 --> 00:15:42,280 Speaker 1: the true epigenetics that integrated doctors like us like to 265 00:15:42,320 --> 00:15:44,920 Speaker 1: talk about, is that you can change your environment and 266 00:15:44,960 --> 00:15:47,720 Speaker 1: your whole condition and your whole health outcomes will be 267 00:15:47,800 --> 00:15:50,560 Speaker 1: completely different. It's it is quite plastic, but at that 268 00:15:50,640 --> 00:15:54,360 Speaker 1: mitochondria level, I think it's even more plastic. But it's 269 00:15:54,440 --> 00:15:58,600 Speaker 1: plastic through generations. So it's like nether lives their life 270 00:15:58,720 --> 00:16:02,000 Speaker 1: well through a whole life lifetime and has a baby well, 271 00:16:02,120 --> 00:16:05,360 Speaker 1: and then that child grows up, lives a lifetime well 272 00:16:05,560 --> 00:16:08,840 Speaker 1: through their whole lifetime. And in the last few decades, 273 00:16:08,960 --> 00:16:11,200 Speaker 1: just the last few decades, we've just seen such a 274 00:16:11,280 --> 00:16:15,400 Speaker 1: crazy increase in environmental toxins and stress, and I think 275 00:16:15,960 --> 00:16:18,360 Speaker 1: mitochondria are really seriously copying it. 276 00:16:18,800 --> 00:16:20,920 Speaker 2: Yeah, so the mitochondria. 277 00:16:20,960 --> 00:16:24,960 Speaker 4: Let's come back to the mitochondrial psychobiology. So let's then 278 00:16:25,400 --> 00:16:29,880 Speaker 4: talk about how this manifest from a psychological perspective when 279 00:16:29,880 --> 00:16:33,520 Speaker 4: your mitochondria is not functioning. Well, I'm tipping that that's 280 00:16:33,520 --> 00:16:35,920 Speaker 4: what mitochondrial psychobiology is. 281 00:16:36,480 --> 00:16:40,600 Speaker 1: Yeah, well, I think you should interview Martin Pickard because 282 00:16:40,640 --> 00:16:44,840 Speaker 1: he is still just doing the research, and the research 283 00:16:44,880 --> 00:16:48,760 Speaker 1: is in the very early days, but it is pointing 284 00:16:48,920 --> 00:16:55,320 Speaker 1: to that just how your mind frame is. So let's 285 00:16:55,320 --> 00:16:59,000 Speaker 1: say in a week, you might wake up like really 286 00:16:59,040 --> 00:17:01,840 Speaker 1: bright and chirpy three days a week, and like just 287 00:17:01,960 --> 00:17:05,080 Speaker 1: normal two days a week, and then maybe really sad 288 00:17:05,160 --> 00:17:07,240 Speaker 1: or something's really got you down, or you just or 289 00:17:07,640 --> 00:17:09,920 Speaker 1: wake up on the wrong side of bed two days 290 00:17:09,920 --> 00:17:13,840 Speaker 1: a week. And they're doing some work that's showing that 291 00:17:14,320 --> 00:17:19,400 Speaker 1: just how you feel that day will change your bioenergetics. 292 00:17:19,400 --> 00:17:24,200 Speaker 1: Bio energetics bio energetics meaning how well is your redox 293 00:17:24,280 --> 00:17:27,560 Speaker 1: capacity going through the mitochondria, how well will you do 294 00:17:27,680 --> 00:17:32,000 Speaker 1: that whole energy exchange, you know, atp energy all of that. 295 00:17:32,560 --> 00:17:37,400 Speaker 1: So he's obviously deep into the metabolism and biology of that, 296 00:17:37,440 --> 00:17:40,720 Speaker 1: but he's now bringing in how does the mind also 297 00:17:40,800 --> 00:17:44,480 Speaker 1: change that it's a top down, bottom up change. 298 00:17:44,240 --> 00:17:47,199 Speaker 7: Right, I was going to ask, I presume it's a 299 00:17:47,240 --> 00:17:50,320 Speaker 7: two way thing, right, because Chris Palmer has shown you 300 00:17:50,440 --> 00:17:54,280 Speaker 7: damage your mitochondria, you're more likely to get our whole 301 00:17:54,320 --> 00:17:56,040 Speaker 7: hopes of brand conditions. 302 00:17:56,080 --> 00:17:59,360 Speaker 4: And with Brian, let's include mental health as weever near 303 00:17:59,440 --> 00:18:03,160 Speaker 4: to generate diseases. But you know what you're saying now 304 00:18:03,320 --> 00:18:07,040 Speaker 4: is that your psychological stee it can then impact your 305 00:18:07,040 --> 00:18:10,280 Speaker 4: bio energetics. Now that makes sense because we know that 306 00:18:10,320 --> 00:18:14,440 Speaker 4: your psychological steate it can change the composition about microbio. 307 00:18:14,880 --> 00:18:17,919 Speaker 4: We know that it can release inflammatory markers as well, 308 00:18:17,960 --> 00:18:22,719 Speaker 4: which then can impact widespread threating body. So it's not 309 00:18:22,800 --> 00:18:26,080 Speaker 4: a crazy lead to suggest that it would affect how 310 00:18:26,119 --> 00:18:27,320 Speaker 4: your magic dria function. 311 00:18:27,640 --> 00:18:30,760 Speaker 1: That's right. It's just it's very new in actually being 312 00:18:30,800 --> 00:18:34,280 Speaker 1: mapped out in research in the publications. I know it 313 00:18:34,320 --> 00:18:36,520 Speaker 1: makes sense to you and me, but this is just 314 00:18:36,600 --> 00:18:38,919 Speaker 1: what they're starting to find out. And it's not to 315 00:18:38,960 --> 00:18:42,280 Speaker 1: say that, oh, someone with a significant mitochondrial disorder, if 316 00:18:42,320 --> 00:18:44,639 Speaker 1: you just well just make yourself feel better, you know, 317 00:18:44,720 --> 00:18:47,520 Speaker 1: do some laughter, younger and laugh and things like that. 318 00:18:47,920 --> 00:18:50,040 Speaker 1: But I know It's not as simple as that, because 319 00:18:50,080 --> 00:18:54,679 Speaker 1: people out there definitely are struggling with some really difficult diseases. 320 00:18:55,160 --> 00:18:57,640 Speaker 1: But what I'm trying to impress upon people is that, 321 00:18:58,000 --> 00:19:02,200 Speaker 1: you know, mitochondria, bio energetics is a native It adds 322 00:19:02,280 --> 00:19:06,520 Speaker 1: up everything. Everything you do counts. It's not just your nutrition. 323 00:19:06,680 --> 00:19:09,960 Speaker 1: That time is sleep, the light, the nature, the water 324 00:19:10,040 --> 00:19:13,080 Speaker 1: you drink, how well you detox your body, how much 325 00:19:13,119 --> 00:19:15,199 Speaker 1: you sweat, how much cold you do. It's like we 326 00:19:15,320 --> 00:19:18,399 Speaker 1: stack it, right. So nowadays we talk about biostacking. We 327 00:19:18,440 --> 00:19:20,600 Speaker 1: don't talk about biohacking. 328 00:19:20,880 --> 00:19:21,640 Speaker 2: Right of stacking. 329 00:19:21,680 --> 00:19:26,320 Speaker 1: I like it. Biohacking is last decade. 330 00:19:26,080 --> 00:19:30,840 Speaker 4: Yeah, but it's it has real world implications for people. 331 00:19:30,960 --> 00:19:32,840 Speaker 2: Right, So let's make this real. 332 00:19:33,680 --> 00:19:36,000 Speaker 4: It's getting back to what you said earlier on about 333 00:19:36,000 --> 00:19:39,040 Speaker 4: the inputs, right. And so if we just take the 334 00:19:39,240 --> 00:19:44,800 Speaker 4: mitochondary of psychobiology, if people are listening to lots of 335 00:19:44,880 --> 00:19:49,960 Speaker 4: news stuff, right, all the negative news stuff. Human beings 336 00:19:50,000 --> 00:19:55,640 Speaker 4: were not designed to hear about all the terrible atrocities 337 00:19:55,680 --> 00:19:58,360 Speaker 4: that are happening to millions of people around the world, right, 338 00:19:58,400 --> 00:20:02,040 Speaker 4: that's not what we are designed. But then also, and 339 00:20:02,119 --> 00:20:05,120 Speaker 4: particularly when you think about our teenagers, spending a lot 340 00:20:05,160 --> 00:20:09,119 Speaker 4: of time on social media, and especially this upwards comparison, 341 00:20:09,520 --> 00:20:11,320 Speaker 4: which I think is really toxic. 342 00:20:11,680 --> 00:20:13,840 Speaker 2: You know, when we were kids, the. 343 00:20:13,880 --> 00:20:17,040 Speaker 4: Natural condition to the brain is to compare yourself to others, 344 00:20:17,040 --> 00:20:19,240 Speaker 4: particularly when you're a teenager, because you're trying to work 345 00:20:19,280 --> 00:20:22,879 Speaker 4: out your place in the tribe. We were exposed to 346 00:20:22,880 --> 00:20:26,480 Speaker 4: maybe one hundred other teenagers at our school around the 347 00:20:26,520 --> 00:20:31,200 Speaker 4: scene age of us. But no people are exposed to thousands, 348 00:20:31,240 --> 00:20:34,840 Speaker 4: and they're seeing the best little herb brush snapshots of 349 00:20:34,920 --> 00:20:38,920 Speaker 4: people who are more handsome, more pretty, more successful, more 350 00:20:39,040 --> 00:20:43,520 Speaker 4: lean than them. And then that creates just negative energy, 351 00:20:44,320 --> 00:20:47,760 Speaker 4: which then is going to impact upon your mitochondria negatively, 352 00:20:47,880 --> 00:20:50,520 Speaker 4: so that in and of itself is shit house for 353 00:20:50,560 --> 00:20:51,200 Speaker 4: your microcongreer. 354 00:20:51,280 --> 00:20:52,360 Speaker 2: I think that's a medical term. 355 00:20:52,760 --> 00:20:56,160 Speaker 4: But then you add in exposure to all of these 356 00:20:56,240 --> 00:21:01,640 Speaker 4: environmental toxins, ultra process foods, lack of physical activity, lack 357 00:21:01,680 --> 00:21:05,919 Speaker 4: of sunlight, it's not hard to see how modern life 358 00:21:06,200 --> 00:21:08,440 Speaker 4: is toxic to the mitochondria. 359 00:21:08,760 --> 00:21:11,760 Speaker 1: Yeah, I couldn't put it better than that. That is tough. 360 00:21:11,800 --> 00:21:14,160 Speaker 1: That is the real world, and that's why the more 361 00:21:14,720 --> 00:21:18,000 Speaker 1: we educate people, and that's why this is amazing. This 362 00:21:18,080 --> 00:21:21,560 Speaker 1: podcast that you do because it's teaching the generations. And 363 00:21:21,600 --> 00:21:24,680 Speaker 1: for me, I'm treating very sick and very chronic difficult patients. 364 00:21:24,720 --> 00:21:28,040 Speaker 1: I'm just trying to pull together every single little ten 365 00:21:28,400 --> 00:21:31,240 Speaker 1: to fifteen to twenty percent of things that could be 366 00:21:31,320 --> 00:21:35,640 Speaker 1: different to help them mitochondrial bio energetics. And so that's 367 00:21:35,640 --> 00:21:37,439 Speaker 1: why I'll come back to what I was saying. I 368 00:21:37,480 --> 00:21:39,920 Speaker 1: know it's no fun to be in a lot of 369 00:21:40,000 --> 00:21:45,200 Speaker 1: chronic pain and deal with a big condition, but one 370 00:21:45,240 --> 00:21:49,439 Speaker 1: still has to change the immediate environment. Sensory felt lived, 371 00:21:49,880 --> 00:21:51,840 Speaker 1: moved environment around them. 372 00:21:52,040 --> 00:21:56,000 Speaker 4: I like that sensory felt lived, moved environment. That's pretty cool. 373 00:21:56,280 --> 00:21:57,840 Speaker 4: There's a couple of other things I want to talk 374 00:21:57,880 --> 00:22:00,400 Speaker 4: to if if I can just get a little bit more, because. 375 00:22:00,200 --> 00:22:01,200 Speaker 2: I'm loving this conversation. 376 00:22:01,320 --> 00:22:04,560 Speaker 4: So I want people to walk away with an understanding 377 00:22:04,560 --> 00:22:08,119 Speaker 4: about how they can improve their mitochondrial health. Right, So 378 00:22:08,960 --> 00:22:12,360 Speaker 4: before we go high level, so we we'll get into 379 00:22:12,400 --> 00:22:15,960 Speaker 4: again that's the whole century lived environment, but let's really 380 00:22:16,000 --> 00:22:22,000 Speaker 4: talk about the mitochondrial complexes and how nutrition and nutrients 381 00:22:22,240 --> 00:22:27,040 Speaker 4: play into those different complexes. Right, Because my understanding is 382 00:22:27,080 --> 00:22:29,880 Speaker 4: that the bee vinamins, some of the bee vinamins are 383 00:22:29,880 --> 00:22:33,560 Speaker 4: really important in this we know, I think, and I 384 00:22:33,600 --> 00:22:37,040 Speaker 4: was going to ask you about this, if NAD has 385 00:22:37,080 --> 00:22:41,159 Speaker 4: an impact on complex one, and then we know that 386 00:22:41,240 --> 00:22:43,879 Speaker 4: red light has an impact on complex four. So what 387 00:22:44,200 --> 00:22:45,840 Speaker 4: are some of the things that people should be thinking 388 00:22:45,840 --> 00:22:51,160 Speaker 4: about nutritionally to support their magochondrial health. 389 00:22:51,960 --> 00:22:57,200 Speaker 1: Okay, so nutritionally, so just food, I would start off 390 00:22:57,240 --> 00:22:59,840 Speaker 1: with what time you eat, I would say, or eat 391 00:23:00,160 --> 00:23:04,320 Speaker 1: daylight hours, because what time you eat is setting up 392 00:23:04,359 --> 00:23:07,440 Speaker 1: your cicaian rhythms, and your circadian rhythms do also talk 393 00:23:07,480 --> 00:23:10,440 Speaker 1: to your mitochondria pathways. So it's not what you eat 394 00:23:10,560 --> 00:23:13,359 Speaker 1: just it's also what time you eat. And so to 395 00:23:13,440 --> 00:23:15,679 Speaker 1: set out what time you eat, I think it's always 396 00:23:15,720 --> 00:23:18,240 Speaker 1: a good breakfast. And then if you're trying to fast 397 00:23:18,400 --> 00:23:21,120 Speaker 1: because there is weight fat to be burned and weight 398 00:23:21,200 --> 00:23:24,159 Speaker 1: to be lost, and fast at night, which is the 399 00:23:24,240 --> 00:23:28,200 Speaker 1: other way to what people like to do because of convenience. 400 00:23:28,680 --> 00:23:30,840 Speaker 2: So I'm wee on that one, by the way. 401 00:23:31,040 --> 00:23:36,240 Speaker 1: Yeah, breakfast like a king, right, yes? Or skip it? 402 00:23:37,240 --> 00:23:41,440 Speaker 1: So time what time you eat? And then the next 403 00:23:41,480 --> 00:23:45,119 Speaker 1: thing I'd moved to is the macro nutrient ratio. So 404 00:23:45,240 --> 00:23:50,400 Speaker 1: the macro nutrient ratio is fat, carbs, proteins, and in 405 00:23:50,440 --> 00:23:54,479 Speaker 1: the modern world, carves has become a bit of an 406 00:23:54,640 --> 00:23:57,520 Speaker 1: enemy now. It didn't used to be, so I don't 407 00:23:57,560 --> 00:23:59,919 Speaker 1: want to say like all carps is bad. Didn't use 408 00:24:00,080 --> 00:24:03,080 Speaker 1: to be. And I remember ten years ago, is traveling 409 00:24:03,080 --> 00:24:06,480 Speaker 1: in Bhutan, and you know, I'm like, everyone needs to 410 00:24:06,520 --> 00:24:09,040 Speaker 1: be low carb, Like everyone's got metabolic syndrome. All my 411 00:24:09,040 --> 00:24:12,119 Speaker 1: patients and metabolic syndrome, and they do. And then I 412 00:24:12,200 --> 00:24:14,879 Speaker 1: go to Bhutan and they're all eating huge piles of 413 00:24:15,000 --> 00:24:19,600 Speaker 1: rice and that's right. There's no one overweight here, you know. 414 00:24:20,520 --> 00:24:23,960 Speaker 1: And I means like giant mountain men eating huge piles 415 00:24:24,000 --> 00:24:26,280 Speaker 1: of rice and they're out in nature and they're walking around. 416 00:24:26,760 --> 00:24:31,000 Speaker 1: So I realized, oh, yeah, it's only when our mitochondria 417 00:24:31,080 --> 00:24:35,080 Speaker 1: are in this modern environment blue light, toxic, not moving, 418 00:24:35,160 --> 00:24:39,479 Speaker 1: not exercising, then you need to eat lower carb. So 419 00:24:39,520 --> 00:24:41,520 Speaker 1: for some people that need to be very low carb 420 00:24:41,640 --> 00:24:45,520 Speaker 1: depends on how what kind of mitochondria, genetics, and what 421 00:24:45,560 --> 00:24:48,239 Speaker 1: the microbiome is like. And for some people they can 422 00:24:48,359 --> 00:24:52,399 Speaker 1: eat much more, especially if they're moving it exercising. So 423 00:24:52,520 --> 00:24:56,280 Speaker 1: macro nutrients would be really think about the carbohydrate and 424 00:24:56,320 --> 00:24:58,960 Speaker 1: then really topping up on the protein and then topping 425 00:24:59,000 --> 00:25:03,000 Speaker 1: up on heaps of five and good fats. So macronutrient 426 00:25:03,000 --> 00:25:03,680 Speaker 1: would be next. 427 00:25:04,200 --> 00:25:06,040 Speaker 2: Yeah, yeah, okay, cool, let's do that. 428 00:25:06,520 --> 00:25:10,040 Speaker 1: So that's time you eat, then the macronutrient, then the micronutrients, 429 00:25:10,040 --> 00:25:12,600 Speaker 1: so that would be the vitamins and the minerals. So 430 00:25:12,800 --> 00:25:15,520 Speaker 1: I wouldn't jump straight to saying take the supplement, take 431 00:25:15,560 --> 00:25:19,160 Speaker 1: that supplement. But does depend on someone's age and stage 432 00:25:19,280 --> 00:25:21,120 Speaker 1: and do they have a condition and what are they're 433 00:25:21,119 --> 00:25:25,399 Speaker 1: trying to achieve. But if their nutrition is good with 434 00:25:25,480 --> 00:25:28,240 Speaker 1: a lot of nutrient density of you know, I think 435 00:25:28,320 --> 00:25:31,840 Speaker 1: liver is really good. I think humans should eat omnivorous, 436 00:25:32,359 --> 00:25:35,520 Speaker 1: So I do think that liver has got a lot 437 00:25:35,560 --> 00:25:39,359 Speaker 1: of bee vitamins. And if you eat enough protein, then 438 00:25:39,400 --> 00:25:43,080 Speaker 1: you get lots of your carnotene and you're tourine, so 439 00:25:43,119 --> 00:25:46,400 Speaker 1: those are nutrients important for the mitochondria. You get lots 440 00:25:46,440 --> 00:25:51,200 Speaker 1: of your creatine and then if you eat lots of vegetables, 441 00:25:51,440 --> 00:25:54,720 Speaker 1: nutzis and you're getting your minerals and you electrolytes. But 442 00:25:54,880 --> 00:25:58,840 Speaker 1: let's face it, like today's modern agriculture, the food is 443 00:25:58,920 --> 00:26:01,600 Speaker 1: really quite depleted quite a lot of things, The soils 444 00:26:01,600 --> 00:26:06,159 Speaker 1: are quite deplete, nutrients. So if someone was really really 445 00:26:06,240 --> 00:26:09,280 Speaker 1: super well and doesn't need any supplement, I would say 446 00:26:09,280 --> 00:26:12,359 Speaker 1: they still need the supplement, and that is they still 447 00:26:12,400 --> 00:26:15,399 Speaker 1: need minerals. So I would always supplement from. 448 00:26:16,520 --> 00:26:21,520 Speaker 4: A multi or are specific stuff for people generally, Like. 449 00:26:21,520 --> 00:26:25,240 Speaker 1: A super well fit person just needs to take minerals, 450 00:26:25,280 --> 00:26:28,919 Speaker 1: then I would propose a multi mineral supplement like with 451 00:26:29,200 --> 00:26:32,119 Speaker 1: all the trace minerals in it as well, not just 452 00:26:32,240 --> 00:26:36,720 Speaker 1: like just think selenium, chromium, molygdinum, all of those are 453 00:26:36,720 --> 00:26:40,400 Speaker 1: the big ticket ones, but trace minerals are really good. 454 00:26:40,440 --> 00:26:43,000 Speaker 1: So you get lots of trace minerals from sea salt, 455 00:26:43,080 --> 00:26:48,080 Speaker 1: electrolyte and sea salt mineral products, So those are always 456 00:26:48,119 --> 00:26:53,600 Speaker 1: my favorite supplements that would be the top priority in everyone. Electrolytes, 457 00:26:53,880 --> 00:26:58,000 Speaker 1: sea salt minerals, and potassium. So a lot of people 458 00:26:58,080 --> 00:27:02,040 Speaker 1: are depleted in potassium. So I know that nowadays with 459 00:27:02,160 --> 00:27:05,440 Speaker 1: a lot of the big biohacking movements and sports and 460 00:27:05,480 --> 00:27:09,320 Speaker 1: longevity runs taking electrolytes, which is great, but we really 461 00:27:09,359 --> 00:27:10,360 Speaker 1: need the potassium. 462 00:27:10,440 --> 00:27:11,320 Speaker 2: Yeah, and a. 463 00:27:11,280 --> 00:27:15,320 Speaker 4: Lot of people there, Yeah, they just tweak the potassium levels. 464 00:27:15,320 --> 00:27:18,080 Speaker 4: It can sort out the blood pressure as well. I 465 00:27:18,119 --> 00:27:20,840 Speaker 4: think there's a bit too much focus on sodium and 466 00:27:20,880 --> 00:27:22,240 Speaker 4: not enough on potassium. 467 00:27:23,040 --> 00:27:27,840 Speaker 1: Yeah, yeah, yeah, big time. So that would be the vitamins. 468 00:27:28,200 --> 00:27:31,360 Speaker 1: Supplements I think everyone should have would be electrolytes and minerals. 469 00:27:31,400 --> 00:27:34,760 Speaker 1: And then, like I said, with a condition and with 470 00:27:35,040 --> 00:27:37,920 Speaker 1: health issues, and I would certainly go for the ubiquanal 471 00:27:38,520 --> 00:27:42,480 Speaker 1: I would do creating NAD. I wouldn't necessarily do n 472 00:27:42,640 --> 00:27:45,200 Speaker 1: D because that's quite expensive. Not everyone can afford that, 473 00:27:45,280 --> 00:27:48,960 Speaker 1: but definitely be three, so a nice cinemaide of sorts. 474 00:27:49,480 --> 00:27:53,399 Speaker 1: And then most people can take a multib complex, but 475 00:27:53,560 --> 00:27:56,960 Speaker 1: some people cannot if depending on their methylation status, they 476 00:27:57,040 --> 00:27:57,680 Speaker 1: might get a bit. 477 00:27:57,840 --> 00:28:02,280 Speaker 4: Do you propose a method vitamin for people or does 478 00:28:02,320 --> 00:28:05,480 Speaker 4: that not work well for some people? Like what I'm saying, 479 00:28:05,480 --> 00:28:09,879 Speaker 4: should everybody take methylated B or can methalate B not 480 00:28:09,960 --> 00:28:12,760 Speaker 4: be great depending on certain genes. 481 00:28:12,560 --> 00:28:16,440 Speaker 1: The latter, so I don't propose methylated B broadly speaking, 482 00:28:17,000 --> 00:28:21,200 Speaker 1: I would propose so if we're talking first about energy mitochondria, 483 00:28:21,280 --> 00:28:23,840 Speaker 1: propose B three and B five. And then if we 484 00:28:23,960 --> 00:28:26,760 Speaker 1: just want an round B, then I would say a 485 00:28:26,920 --> 00:28:30,080 Speaker 1: multibe that doesn't necessarily have a lot of methylated bees. 486 00:28:30,200 --> 00:28:32,520 Speaker 1: But yeah, a bit of B two lots of B 487 00:28:32,640 --> 00:28:35,960 Speaker 1: one as well, but methylated bees don't go well with 488 00:28:36,600 --> 00:28:39,920 Speaker 1: at least in my patient cohort, because I have tough 489 00:28:40,320 --> 00:28:43,200 Speaker 1: cases and that's usually when other things haven't worked. And 490 00:28:43,640 --> 00:28:47,280 Speaker 1: usually in that community, methylated b can cause a lot 491 00:28:47,320 --> 00:28:53,040 Speaker 1: more anxiety agro agitation because people have folate follate receptive 492 00:28:53,040 --> 00:28:56,080 Speaker 1: blocks or methyl blocks so they can't methylate the folates 493 00:28:56,160 --> 00:28:57,080 Speaker 1: and things like that. 494 00:28:57,360 --> 00:29:03,840 Speaker 4: Yeah, interesting, And what is your thoughts on NMN and 495 00:29:04,520 --> 00:29:09,600 Speaker 4: NR right, because they're big in the kind of biohacking communities, 496 00:29:10,400 --> 00:29:12,960 Speaker 4: Just keen to get your thoughts. I took a little 497 00:29:12,960 --> 00:29:15,440 Speaker 4: bit of NME and sublingual, and then I just stopped 498 00:29:15,480 --> 00:29:18,000 Speaker 4: because for me, I looked at the research. Now this 499 00:29:18,160 --> 00:29:21,320 Speaker 4: was a year ago, and there wasn't a lot of 500 00:29:21,600 --> 00:29:25,040 Speaker 4: what I thought was compelling human data. But I know 501 00:29:25,120 --> 00:29:28,239 Speaker 4: a lot of people absolutely swear by it. What's your 502 00:29:28,280 --> 00:29:28,760 Speaker 4: thoughts on it? 503 00:29:29,440 --> 00:29:33,480 Speaker 1: So I'm a bit neutral about needing to do NMN 504 00:29:33,600 --> 00:29:38,360 Speaker 1: or NR versus just B three, partly because I'm working 505 00:29:38,400 --> 00:29:42,440 Speaker 1: with a patient community with chronic diseases and they often 506 00:29:42,520 --> 00:29:45,800 Speaker 1: don't have a lot of funds because there's a lot 507 00:29:45,840 --> 00:29:47,720 Speaker 1: of supplements to have to take in the end you know, 508 00:29:48,160 --> 00:29:51,680 Speaker 1: I do. I do give people relatively big protocols that 509 00:29:51,880 --> 00:29:54,760 Speaker 1: I'm being conservative, but I also it does also add 510 00:29:54,840 --> 00:29:56,640 Speaker 1: up to a lot of things. You have to support 511 00:29:57,240 --> 00:29:59,200 Speaker 1: the bio, you have to support the liver, you have 512 00:29:59,200 --> 00:30:01,600 Speaker 1: to support the micro bio, you have to support the 513 00:30:01,640 --> 00:30:04,160 Speaker 1: nearer transmitters. In the end, you have a supplements as 514 00:30:04,200 --> 00:30:06,760 Speaker 1: long as you know, list of it, as long as 515 00:30:06,760 --> 00:30:12,040 Speaker 1: your arm. So cost wise, EMIN is not practical for 516 00:30:12,120 --> 00:30:17,000 Speaker 1: my patient cohort. The research looks interesting. I'm not jumping 517 00:30:17,040 --> 00:30:20,840 Speaker 1: straight into that because of being practical, and I already 518 00:30:20,920 --> 00:30:23,720 Speaker 1: see good results with B three and just n R, 519 00:30:24,480 --> 00:30:27,479 Speaker 1: and I already see good results of using other things 520 00:30:27,520 --> 00:30:30,120 Speaker 1: in my patient groups. So I don't just hammer in 521 00:30:30,200 --> 00:30:30,400 Speaker 1: on that. 522 00:30:30,640 --> 00:30:33,360 Speaker 4: Andemen my view on that is a watch in we 523 00:30:33,480 --> 00:30:36,080 Speaker 4: it because it is bloody expensive. It's a supplement, and 524 00:30:36,120 --> 00:30:38,880 Speaker 4: I think there's there's other ones that are kind of 525 00:30:38,960 --> 00:30:39,960 Speaker 4: top of the list on that. 526 00:30:40,480 --> 00:30:43,240 Speaker 2: Okay. So and then just to remind our people, so 527 00:30:43,520 --> 00:30:44,240 Speaker 2: is that that's. 528 00:30:44,080 --> 00:30:46,400 Speaker 4: Everything from a nutritional perspective, is it? 529 00:30:46,440 --> 00:30:48,520 Speaker 1: And then well I'll put the last thing in is 530 00:30:48,560 --> 00:30:51,520 Speaker 1: also when you don't eat, so you know a bit 531 00:30:51,520 --> 00:30:55,960 Speaker 1: of fasting is depends again on the person. But if 532 00:30:56,280 --> 00:30:59,880 Speaker 1: you're trying to get more metabolic flexibility, then it's good 533 00:31:00,080 --> 00:31:04,280 Speaker 1: to be able to fast, and fasting just means to 534 00:31:04,320 --> 00:31:08,720 Speaker 1: be able to not eat overnight twelve to fourteen hours 535 00:31:09,000 --> 00:31:11,560 Speaker 1: and okay, sometimes if you had to skip lunch because 536 00:31:11,560 --> 00:31:14,640 Speaker 1: you really were that busy, or you skip dinner, you 537 00:31:14,680 --> 00:31:17,920 Speaker 1: don't fall apart because you're angry, you know. So it's 538 00:31:17,960 --> 00:31:21,400 Speaker 1: like be able to not be like that. So people 539 00:31:21,480 --> 00:31:23,800 Speaker 1: have to work out how to be able to fast 540 00:31:23,920 --> 00:31:26,360 Speaker 1: and get through that. So not saying that you need 541 00:31:26,440 --> 00:31:30,480 Speaker 1: to do long fast for mitochondrial health, but you have 542 00:31:30,560 --> 00:31:32,200 Speaker 1: to be able to handle a fast. 543 00:31:32,520 --> 00:31:35,280 Speaker 4: Yeah, absolutely, every human beings should be able to handle 544 00:31:35,280 --> 00:31:38,840 Speaker 4: a fast. Right, then the other things to throw at 545 00:31:38,920 --> 00:31:42,720 Speaker 4: your mitochondria other than so that's a very detailed thing 546 00:31:42,760 --> 00:31:45,760 Speaker 4: around nutrition. What's the other big ticket items for you? 547 00:31:45,880 --> 00:31:49,640 Speaker 1: Big ticket items would be avoid blue light, so get 548 00:31:49,640 --> 00:31:52,600 Speaker 1: the light, right, we already said that, and so using 549 00:31:52,640 --> 00:31:55,600 Speaker 1: a red light panel or red light devices is really 550 00:31:55,680 --> 00:31:58,080 Speaker 1: just to tip that balance of we're just a bit 551 00:31:58,120 --> 00:32:01,680 Speaker 1: too much blue and not enough friend. But if someone 552 00:32:01,760 --> 00:32:04,200 Speaker 1: is out in nature the whole day and getting a 553 00:32:04,200 --> 00:32:07,120 Speaker 1: lot of sun, then you don't necessarily need a red 554 00:32:07,200 --> 00:32:10,800 Speaker 1: light like just a generic red light panel I'm talking about. 555 00:32:10,920 --> 00:32:14,600 Speaker 1: You might use red light to specifically treat an ankle 556 00:32:14,680 --> 00:32:18,360 Speaker 1: injury on elbow spray and things like that, so that'd 557 00:32:18,400 --> 00:32:20,560 Speaker 1: be the blue and the red. And the next thing 558 00:32:20,600 --> 00:32:22,040 Speaker 1: I would say is do cold. 559 00:32:23,200 --> 00:32:27,200 Speaker 4: Yeah, can induce mitochondrial biogenesis. 560 00:32:26,440 --> 00:32:30,800 Speaker 1: Right, very very very powerful cold therapy. So that's a 561 00:32:30,880 --> 00:32:34,479 Speaker 1: huge with chondrial therapy. And depending on the type of 562 00:32:34,560 --> 00:32:37,840 Speaker 1: communities you're speaking to, maybe your communities Paul are like 563 00:32:37,960 --> 00:32:41,720 Speaker 1: all out there jumping into ice bath and going gung 564 00:32:41,800 --> 00:32:44,480 Speaker 1: ho for it, but my patient community isn't so much 565 00:32:44,520 --> 00:32:46,880 Speaker 1: because people have chronic fatigue and so on. So we 566 00:32:47,040 --> 00:32:49,239 Speaker 1: just have to do it very slow and gently, and 567 00:32:49,280 --> 00:32:51,440 Speaker 1: we usually start doing it with face plunges. 568 00:32:52,000 --> 00:32:52,240 Speaker 2: Yeah. 569 00:32:52,400 --> 00:32:54,680 Speaker 4: Yeah, I think that's a really good thing for people 570 00:32:54,720 --> 00:32:58,280 Speaker 4: who have chronic conditions. If they jump into an ice bath, 571 00:32:58,320 --> 00:33:01,280 Speaker 4: that can just be too much and can completely overwhelm them. 572 00:33:01,320 --> 00:33:04,080 Speaker 4: So the asponges I totally agree with you a great 573 00:33:04,160 --> 00:33:06,800 Speaker 4: and then maybe a bit of a cold char it's 574 00:33:06,800 --> 00:33:08,840 Speaker 4: just at the end of your normal char. But you know, 575 00:33:08,880 --> 00:33:10,920 Speaker 4: you don't have to be jumping into the ice bot 576 00:33:10,960 --> 00:33:12,920 Speaker 4: and you certainly don't need to be spending ten minutes 577 00:33:12,920 --> 00:33:16,120 Speaker 4: in an icepot. That's just an ego trip. I think 578 00:33:16,440 --> 00:33:20,800 Speaker 4: most of the benefits are those first twenty seconds when 579 00:33:20,800 --> 00:33:24,800 Speaker 4: you get into cold water. And what about exercise. 580 00:33:25,640 --> 00:33:29,920 Speaker 1: I was going to say that one next it's like, okay, 581 00:33:30,200 --> 00:33:34,280 Speaker 1: it's so next thing with the exercise. So with my 582 00:33:34,360 --> 00:33:37,240 Speaker 1: patient community, I guess I don't use the word exercise. 583 00:33:37,280 --> 00:33:38,160 Speaker 1: I talk about. 584 00:33:37,920 --> 00:33:39,520 Speaker 2: Movement physical activity. 585 00:33:39,960 --> 00:33:43,520 Speaker 1: Yeah, when they have cronic fatigue, they do get upset 586 00:33:43,600 --> 00:33:45,560 Speaker 1: with being told they have to exercise because it makes 587 00:33:45,560 --> 00:33:48,880 Speaker 1: them sicker. And so but I say to them, you 588 00:33:48,960 --> 00:33:52,720 Speaker 1: still absolutely need to move. You cannot just sit down 589 00:33:52,800 --> 00:33:55,880 Speaker 1: or lie down. When people have got pots and you 590 00:33:55,920 --> 00:33:59,280 Speaker 1: know orthostatic intolerance, they're lying down and sitting down a lot. 591 00:34:00,320 --> 00:34:03,080 Speaker 1: You still absolutely need to move. So we need to 592 00:34:03,120 --> 00:34:07,000 Speaker 1: move for that moto biogenesis, and that is critical too. 593 00:34:07,160 --> 00:34:10,280 Speaker 1: And we might even just start the movement with breath. 594 00:34:11,400 --> 00:34:14,239 Speaker 1: So do use a lot of breath, do a lot 595 00:34:14,280 --> 00:34:18,920 Speaker 1: of our line movements, pilates, care work, and just starting 596 00:34:18,960 --> 00:34:21,840 Speaker 1: with that because that essentially is the most important place. 597 00:34:21,920 --> 00:34:24,840 Speaker 1: That from a functional perspective, is how I'm thinking of it, 598 00:34:24,960 --> 00:34:29,240 Speaker 1: not just big bulky muscles for metabolic health. I'm thinking 599 00:34:29,320 --> 00:34:32,239 Speaker 1: first just the right muscles. Doing the right things is 600 00:34:32,280 --> 00:34:37,520 Speaker 1: really around our breath, our pelvic flaw, our diaphragm, and 601 00:34:37,560 --> 00:34:41,520 Speaker 1: how that makes a big difference to our neurophysiology. 602 00:34:41,800 --> 00:34:45,960 Speaker 2: Yeah, I love it. And the old classic concept of exercise. 603 00:34:46,040 --> 00:34:48,360 Speaker 4: I think it does apply to people with chronic particular 604 00:34:48,360 --> 00:34:52,040 Speaker 4: of seeing research on it is slow progressive overload. Is 605 00:34:52,080 --> 00:34:54,640 Speaker 4: that just week by week, just add a little bit 606 00:34:54,680 --> 00:34:56,640 Speaker 4: and add a little bit and add a little bit, 607 00:34:56,719 --> 00:34:58,480 Speaker 4: and then if it's too much, you just back off 608 00:34:58,480 --> 00:35:01,440 Speaker 4: a little bit. But I think that concept of progressive 609 00:35:01,480 --> 00:35:03,920 Speaker 4: over a little it applies to everybody, from people with 610 00:35:04,040 --> 00:35:08,240 Speaker 4: chronic conditions all the way through to elite athletes like Christine. 611 00:35:08,280 --> 00:35:10,640 Speaker 4: And so I presume is there anything else that we've 612 00:35:10,719 --> 00:35:14,919 Speaker 4: left off on there? You did talk about your few more, but. 613 00:35:17,000 --> 00:35:21,960 Speaker 1: So would be the big ones, you know, nutrition, light, cold, exercise. 614 00:35:22,400 --> 00:35:26,439 Speaker 1: But I would say magnetism is a really good one 615 00:35:26,440 --> 00:35:29,759 Speaker 1: for mitochondrial health if people have got conditions, so using 616 00:35:29,840 --> 00:35:35,719 Speaker 1: PEMF pulse electromagnetic fields. And then I guess it would 617 00:35:35,760 --> 00:35:38,160 Speaker 1: be remiss of me as a nutritional medicine doctor not 618 00:35:38,280 --> 00:35:42,480 Speaker 1: to talk about the microbiota, the microbiome. I mean, everyone 619 00:35:42,600 --> 00:35:46,719 Speaker 1: knows that you know the gut brain access microbiome has 620 00:35:46,760 --> 00:35:47,440 Speaker 1: a big. 621 00:35:47,520 --> 00:35:51,040 Speaker 6: Huge effect across everything, but I actually think that's still 622 00:35:51,320 --> 00:35:54,200 Speaker 6: bottom up, and I think the top down to microbiome 623 00:35:54,320 --> 00:35:57,600 Speaker 6: is the stress and the micochondria that speaks the microbiome. 624 00:35:57,600 --> 00:36:00,560 Speaker 1: And I think that research is starting to kind about 625 00:36:00,640 --> 00:36:05,040 Speaker 1: mitochondria microbiome crosstop. So I think that when your mitochondria 626 00:36:05,160 --> 00:36:07,800 Speaker 1: are healthy and you got the right light signals and 627 00:36:07,920 --> 00:36:11,000 Speaker 1: microbiome will be healthier as opposed to just shoving in 628 00:36:11,080 --> 00:36:15,480 Speaker 1: probiotics and of course fiber, of course probiotics, but just. 629 00:36:16,760 --> 00:36:19,160 Speaker 2: Better fermented food as well. Right for the first. 630 00:36:19,000 --> 00:36:23,240 Speaker 1: One, yeah, yeah, And then the last thing is detox 631 00:36:23,360 --> 00:36:26,400 Speaker 1: because we can't help but live in a toxic world. 632 00:36:26,520 --> 00:36:29,560 Speaker 1: So a good old sona and sweat couple of times 633 00:36:29,560 --> 00:36:32,520 Speaker 1: a week is just yeah. Oh, I guess if you're 634 00:36:32,520 --> 00:36:35,120 Speaker 1: exercising hard and you're sweating yours or doing a double 635 00:36:35,200 --> 00:36:35,560 Speaker 1: up there. 636 00:36:36,239 --> 00:36:37,680 Speaker 2: There's what most people don't realize. 637 00:36:37,680 --> 00:36:42,000 Speaker 4: The level lemon detox diet is horseship compared to sweat. 638 00:36:42,120 --> 00:36:45,719 Speaker 2: Right, that is the mediature way. And I guess supporting 639 00:36:45,760 --> 00:36:47,040 Speaker 2: your fierst one and fist. 640 00:36:46,800 --> 00:36:51,279 Speaker 4: To detoxification and processes in the body through you know, 641 00:36:51,719 --> 00:36:54,840 Speaker 4: lots of broccoli, the whole broccoli family, and then onions 642 00:36:54,880 --> 00:36:59,560 Speaker 4: garlics leaks self first supports those two pathways, right. 643 00:36:59,719 --> 00:37:02,319 Speaker 2: Yeah, totally very cool. 644 00:37:02,520 --> 00:37:06,000 Speaker 4: Now I am Are you still taking patients because I'm 645 00:37:06,080 --> 00:37:09,200 Speaker 4: sure there's a shipload of people going I want her 646 00:37:09,239 --> 00:37:09,920 Speaker 4: as my doctor. 647 00:37:10,640 --> 00:37:13,200 Speaker 1: Yeah, yeah, I still take patients. It just depends on 648 00:37:13,239 --> 00:37:16,000 Speaker 1: the time of year and how heavy the loaded Sometimes 649 00:37:16,160 --> 00:37:19,239 Speaker 1: is a bit of a weight, but we're always taking patients. 650 00:37:19,600 --> 00:37:23,839 Speaker 1: So the clinic is next practice gen biome g E 651 00:37:23,960 --> 00:37:28,120 Speaker 1: n b io me. It's sort of a generation biome. 652 00:37:28,200 --> 00:37:33,840 Speaker 1: It's a biosphere of health and soluted genesis Soluto genesis. 653 00:37:33,880 --> 00:37:36,160 Speaker 1: By the way, it's health creation for some of your 654 00:37:36,200 --> 00:37:40,200 Speaker 1: listeners who might not know. We treat diseases for sure, 655 00:37:40,280 --> 00:37:43,560 Speaker 1: but we prefer or would love to just create health. 656 00:37:43,960 --> 00:37:46,719 Speaker 2: Yeah. I love it. I love it. And are you 657 00:37:46,760 --> 00:37:48,000 Speaker 2: on socials or anything? 658 00:37:48,000 --> 00:37:49,399 Speaker 4: It's a person for people. 659 00:37:49,520 --> 00:37:50,600 Speaker 2: Can Are you too busy? 660 00:37:52,719 --> 00:37:57,160 Speaker 1: I'm not unsocial? Yeah. Well, our clinics very busy. Just 661 00:37:57,239 --> 00:38:00,640 Speaker 1: word of mouth and education and our the clinic is 662 00:38:00,719 --> 00:38:05,080 Speaker 1: MITO Core m I t O Core and that is 663 00:38:05,120 --> 00:38:08,720 Speaker 1: the new clinic, which is much more focused on longevity 664 00:38:09,160 --> 00:38:13,920 Speaker 1: and mitochondrial health. It's using much more of a naturopathic model, 665 00:38:14,680 --> 00:38:18,399 Speaker 1: so not necessarily doctors treating diseases, but really for people. 666 00:38:18,440 --> 00:38:20,960 Speaker 2: Yeah, nice, good, the moant to be great. 667 00:38:21,080 --> 00:38:23,240 Speaker 4: Yeah are the They both based in Sydney. 668 00:38:23,600 --> 00:38:25,560 Speaker 1: Yep, they're both in Edgecliff and Sydney. 669 00:38:26,000 --> 00:38:28,400 Speaker 4: Lucky bastards. They get the good weather in the winter 670 00:38:28,520 --> 00:38:33,919 Speaker 4: and they also get your clinics, Christine. This has been 671 00:38:34,400 --> 00:38:41,279 Speaker 4: absolutely awesome, A great dive into the mitochondria, which are hugely, 672 00:38:41,400 --> 00:38:47,800 Speaker 4: hugely important and I think a very very wide lends 673 00:38:48,080 --> 00:38:51,800 Speaker 4: view of the mitochondria. And I think for our listeners 674 00:38:51,840 --> 00:38:54,880 Speaker 4: there's some real actionable stuff because. 675 00:38:54,920 --> 00:38:56,200 Speaker 2: The mitochondria don't funk you. 676 00:38:56,320 --> 00:38:58,320 Speaker 4: Well, you're a basket case. 677 00:38:58,120 --> 00:39:01,799 Speaker 1: Right, Yeah, that's why. Well, you know, join us as 678 00:39:01,920 --> 00:39:07,600 Speaker 1: mitochondriacts and looking at as the chondria and if anyone 679 00:39:07,760 --> 00:39:10,719 Speaker 1: is into longevity and all that, then you should be 680 00:39:10,760 --> 00:39:11,800 Speaker 1: a mitochondriact. 681 00:39:12,719 --> 00:39:16,040 Speaker 4: I love it. I love it, right, that is the 682 00:39:16,080 --> 00:39:19,320 Speaker 4: title of this talk, Why you need to be a mitochondriact. 683 00:39:20,640 --> 00:39:21,320 Speaker 2: So cool. 684 00:39:21,880 --> 00:39:24,400 Speaker 1: I love talking to you. Thank you so much. I 685 00:39:24,440 --> 00:39:27,000 Speaker 1: appreciate the invite. I know I'm speaking to a different 686 00:39:27,400 --> 00:39:30,120 Speaker 1: community than what I'm usually speaking to. So I hope 687 00:39:30,120 --> 00:39:31,240 Speaker 1: this helps your listeners. 688 00:39:31,600 --> 00:39:35,719 Speaker 4: Oh look, absolutely, no doubt helped my listeners immensely. 689 00:39:35,960 --> 00:39:36,640 Speaker 2: That is the great. 690 00:39:36,680 --> 00:39:40,000 Speaker 4: Thank you for giving you your very precious time to 691 00:39:40,320 --> 00:39:41,760 Speaker 4: help our listeners. Awesome. 692 00:39:42,320 --> 00:39:42,680 Speaker 1: Thanks for