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Speaker 1: Supplements and longevity hacks. Yeah right, Yeah, so all over

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Speaker 1: social media there is all sorts of hacks about health

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Speaker 1: span longevity. So this supplement, that supplement, what in your

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Speaker 1: view are the things that are promising and what are

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Speaker 1: some of the things that you see out there that

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Speaker 1: are a little bit of hype or or certainly the

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Speaker 1: very very minor benefit compared to things like exercise and

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Speaker 1: sleep and grinding and those sorts of things.

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Speaker 2: Yeah, so I guess the first thing to let's just

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Speaker 2: say is that supplements are supplementary. So you don't ever

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Speaker 2: want your strategy to primarily be based on supplements. You can't.

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Speaker 2: You can't kind of supplement yourself out of a unhealthy life.

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Speaker 2: That's the first thing to say. To make that point

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Speaker 2: first before I jump into specific ones that your base

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Speaker 2: has to be. You know, your lifestyle. You know you

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Speaker 2: need to be getting really good restorative sleep, you need

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Speaker 2: to be doing something for stress management, you need to

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Speaker 2: be moving your body. There's no replacement for those things. Yeah.

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Speaker 2: Of course, if you let's say you have one week

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Speaker 2: where you're not able to do those things, well, yeah,

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Speaker 2: sure you can get straight back into it. I'm not

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Speaker 2: saying that you can't miss a single day. Of course,

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Speaker 2: life has all its twists and turns, but there's no overall,

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Speaker 2: there's no replacement for those things. Now, if you are

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Speaker 2: doing those things, or you're doing your best on those levels,

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Speaker 2: can you further enhance the benefit through supplements? I think

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Speaker 2: the answer is yes, and even certain certain targeted medications.

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Speaker 2: So you know, I mean one of the biggest studied

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Speaker 2: ones is rappermisin and so this is all it takes

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Speaker 2: us towards this more complicated discussion on fasting and feasting,

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Speaker 2: and you know, that's that's one of the things that's

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Speaker 2: really really important, you know, And in ancestral societies there

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Speaker 2: would be a good balance between times of plenty and

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Speaker 2: times of famine, and so there would be times where

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Speaker 2: you would have a big feed, then there'd be other

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Speaker 2: times where you would be fasting, and so our bodies

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Speaker 2: were being exposed to adversity. That's a very that's a

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Speaker 2: very important principle in general. And so raprimison basically helps

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Speaker 2: to curb this whole situation of us always being in

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Speaker 2: a time of feasting and only rarely being in a

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Speaker 2: time of fasting or famine. So if that's the case

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Speaker 2: with you and you're adding rap and yeah, it's likely

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Speaker 2: going to help. But I would say that and even

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Speaker 2: better approach is to bring an intermittent fasting.

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Speaker 3: So your you.

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Speaker 1: Would be a fan of intermittent fasting.

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Speaker 2: I think it's it's the simple way to shift the

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Speaker 2: balance between you know, again from we also refer to

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Speaker 2: it as M tour and amp kinase. So in general,

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Speaker 2: most people have an excess of that M tour pathway,

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Speaker 2: which is a growth pathway, and not enough of the

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Speaker 2: a mp kinse. Now, especially now we've talked about having

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Speaker 2: you know, having a decent amount of protein in the diet.

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Speaker 2: Now that means you will be pushing emptor Now I'm

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Speaker 2: not going to say M tour is bad. It's all

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Speaker 2: about balance and getting the.

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Speaker 1: Cycling, not being always on exactly, not being always on. Yeah,

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Speaker 1: and I'm glad you brought up protein, right, because there

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Speaker 1: is this tension right between constantly being in growth mode

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Speaker 1: because cancer sales love that, right, and then and cycling

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Speaker 1: out and you know the benefits of the fasting. And

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Speaker 1: what's really interesting because when you because a lot of

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Speaker 1: the stuff, there's some of the longevity crowds are in

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Speaker 1: the camp of you should have a low protein that

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Speaker 1: because you don't want to be chronically activating M tour. Right.

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Speaker 1: There are some people who are in that camp. I

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Speaker 1: myself am not in that camp, and I never say never,

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Speaker 1: I never say absolutely, right, but currently I'm not in

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Speaker 1: that camp where I sit. Obviously, we've talked about all

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Speaker 1: the benefits of protein and of muscle I have landed

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Speaker 1: on and I'll tell you how I got there. So

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Speaker 1: I used to do a lot of intermittent fasting and

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Speaker 1: then find that I had lost with it, but a

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Speaker 1: lot of it was muscle, and so I stopped doing

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Speaker 1: it because I thought, I'm not getting into my fifties

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Speaker 1: and I want to preserve muscle. And then I got

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Speaker 1: diagnosed with my aortic valve and it was probably that

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Speaker 1: that was impacting on you know, because you lose weight

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Speaker 1: with that and you can lose some muscle with that. Right.

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Speaker 1: So I'm kind of back on the intermittent fast entrain.

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Speaker 1: But for me, that the tension here is between getting

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Speaker 1: enough protein and not over stimulating M tour exactly. And

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Speaker 1: for me, a lot of people are doing they're stimulating

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Speaker 1: M tour because it's not just because they're they're not

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Speaker 1: having periods of fasting. But when they're eating, they're they're eating.

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Speaker 1: Say they have a breakfast that's a traditional breakfast that's

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Speaker 1: high carbohydrate and low protein. They're going to be hungry

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Speaker 1: in a couple of hours, so they're going to have

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Speaker 1: a small snack, And a lot of people don't realize

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Speaker 1: that carbohydrate switches on the M tour pathway as well.

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Speaker 1: It's not just protein that switches on the M tour pathway.

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Speaker 1: So for me, it's like, we need to go back

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Speaker 1: to eating three meals a day without snacks, or two

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Speaker 1: meals a day if that suits you, because then you're

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Speaker 1: going to get those bricks. And because if you're just

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Speaker 1: constantly snacking here and there and everywhere, that's when you're

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Speaker 1: chronically switching on am tour.

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Speaker 2: Right, Yes, yes, one hundred. I think that's also a

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Speaker 2: major problem, and just looking at your daily routine. So firstly,

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Speaker 2: I would say intermittent fasting or at least getting to

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Speaker 2: basic levels is not hard. It just takes a bit

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Speaker 2: of attention. So if I go back and think of

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Speaker 2: myself during medical school, I was doing crazy stuff like eating,

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Speaker 2: you know, all through the night, and and you know

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Speaker 2: I was just paying no attention to this concept. But

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Speaker 2: you can start by let's say you eat dinner at

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Speaker 2: six pm. You can start this process, but just making

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Speaker 2: sure you don't eat anymore after you finish your dinner.

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Speaker 2: And then let's say you have breakfast at seven am.

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Speaker 2: You again, you don't eat anything unless you're unless you're

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Speaker 2: a diabetic and you're having a hypoglyceming attack, that would

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Speaker 2: be an exception. But other than that, you don't. You

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Speaker 2: don't eat anything until you have breakfast. So there you go.

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Speaker 2: You're already getting your twelve hours of fasting just through

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Speaker 2: that very basic process of taking out random eating, you know,

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Speaker 2: random snacking. Yeah, yeah, taking that snack out of bedtime. Now,

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Speaker 2: it's fine to have a tea. It's fine to have water,

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Speaker 2: a tea with no milk, that is. So let's say

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Speaker 2: a Herrible tea, cameram ole tea or something like that

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Speaker 2: before bed. I think that's a great idea, no problem

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Speaker 2: with that whatsoever. But having an ice cream or something

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Speaker 2: like that before bed terrible idea because you're not going

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Speaker 2: to digest that ice cream and it's going to block

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Speaker 2: your ability of your body to go into that fasting mode.

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Speaker 2: So then let's say three times a week. You then

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Speaker 2: decide that you're going to finish eating around about four

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Speaker 2: pm rather than seven pm, Well, then you've already pushed

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Speaker 2: that out to fifteen hours on those things. And my

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Speaker 2: understanding is that is the better way to go than

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Speaker 2: trying to extend to your breakfast later on, So that

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Speaker 2: sends to be more physiological, is trying to increase the

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Speaker 2: gap in the evening rather than the morning. So I

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Speaker 2: would say, if you could do that and just and

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Speaker 2: I quite often do it myself. I'll have a smoothie

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Speaker 2: around half past three something like that, and then that's it.

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Speaker 2: I'm done for the evening. I don't have any dinner.

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Speaker 2: The other advantages you find you've got to hit more

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Speaker 2: time available.

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Speaker 1: Yeah, that's right. And you know there will be some

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Speaker 1: people who go, Jesus, half past three and I'm not

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Speaker 1: going to eat again till the morning. How am I

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Speaker 1: going to survey? I would say to these people, because

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Speaker 1: I thought that when I first did that have intimate

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Speaker 1: and fasting. Just run an experiment, right, Just run an experiment,

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Speaker 1: and what you'll find is you won't eat, and you'll

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Speaker 1: wake up in the morning and you won't be dead,

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Speaker 1: and you go Holy shit, look at that. It didn't

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Speaker 1: kill me, and then you can repeat the experiment exactly.

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Speaker 2: And I found personally that it's very easy and actually

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Speaker 2: like my body will yearn for that if I haven't

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Speaker 2: been doing it, it'll crave for a bit of fasting

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Speaker 2: after a while. And you know, some nights I'm like,

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Speaker 2: you know, wanting to get an evening meal, and part

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Speaker 2: of me is like, no, don't do that. So I

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Speaker 2: think it is something that the body naturally craves.

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Speaker 1: I think that one of the most important things that

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Speaker 1: most people could make is to, as you said, stop

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Speaker 1: eating at least three or more ours before you go

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Speaker 1: to bed. I think, Sandy, Well, a lot of people

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Speaker 1: don't realize is that that digestion and absorption is an

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Speaker 1: expensive metabolic process, and that when you eat just before

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Speaker 1: you go to bed, all of that stuff is switched

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Speaker 1: on and a lot of repair mechanisms in the body

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Speaker 1: are switched off because you're in active mode. So just

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Speaker 1: having that gap before you go to bed, it's it's

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Speaker 1: one tweak that if people don't do that, if they're

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Speaker 1: ale at night snacker like that one tweak I think

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Speaker 1: has a significant impact on people.

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Speaker 2: And so for me, personally, being like a midnight snacker

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Speaker 2: didn't really benefit me in any way. It just was

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Speaker 2: just simply lack of awareness. I paid knowledge.

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Speaker 1: Just appetite. It's appetite, isn't it. That's right?

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Speaker 2: Yeah, you're you're up studying, you kind of thinking that, well,

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Speaker 2: maybe I should just eat something to keep my brain going.

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Speaker 2: But I probably didn't need to when I look back.

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Speaker 2: It's just it's just a belief system, isn't it.

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Speaker 1: Absolutely yeah, And its habits. It's habits really. And let's

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Speaker 1: talk about then some more advanced interventions around health span.

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Speaker 1: So injectable nutrients and hormone therapy. You know, where do

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Speaker 1: you start on? And we're assuming here that somebody's doing

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Speaker 1: the fundamentals, right, So maybe we pick a female coming

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Speaker 1: into menopause and a meal about vyads in their fifties,

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Speaker 1: and what's your view. Let's talk about hormone replacement therapy. Yeah,

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Speaker 1: first of all, what's your what's your view on that

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Speaker 1: for the middle aged man and the middle aged woman.

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Speaker 2: Well, yeah, you need you know, hormones are a very

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Speaker 2: very key part of longevity. There's no doubt about it.

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Speaker 2: And we're not saying that you know, you need to

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Speaker 2: keep your levels of hormones at the level of a

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Speaker 2: twenty year old for your entire life. It's okay for

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Speaker 2: them to ease off a little bit, but you don't

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Speaker 2: don't want them to. Like, let's say you're a male

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Speaker 2: in their fifties, you don't want that testosterone in DHA

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Speaker 2: to be in your bootstraps at all. You need to

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Speaker 2: keep them because again, we're talking about muscle mass, we're

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Speaker 2: talking about blood sugar control, and we're talking about cardiovascular health,

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Speaker 2: so testosterone is important for all of those, as well

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Speaker 2: as mood. So a lot of people think of it

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Speaker 2: as more being related to vanity that you're wanting to

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Speaker 2: maintain your testosterone levels, but no, it's actually important for

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Speaker 2: a huge amount of functions and therefore, and so for me,

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Speaker 2: quite often, what I would suggest is to build up

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Speaker 2: the DHA. So many people may not have heard of

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Speaker 2: the hormone called DHA, So it stands for dihydro epi

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Speaker 2: and asterone, so I'm sure you're all going to remember that,

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Speaker 2: but it's like a precursor hormone of testosterone. Now, if

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Speaker 2: you at least have good levels of DHA, it's much

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Speaker 2: more likely you're going to have good levels of testosterone.

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Speaker 2: So then the other thing that's important to know is

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Speaker 2: you want to test your free testosterone. You don't want

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Speaker 2: to test total testosterone because it's very much affected by

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Speaker 2: approachin which we call SHBG. So the free hormone levels

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Speaker 2: are much more important now in Australian units. Once again,

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Speaker 2: you generally want them to be something like three point

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Speaker 2: fifty to six fifty I think that's an animal's polyda,

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Speaker 2: so it's it's the top half of the reference range roughly.

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Speaker 2: So if you're in the bottom of that reference range,

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Speaker 2: well it's not showing as abnormal frankly abnormal on that

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Speaker 2: blood test. But you're you know, you're right here.

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Speaker 1: You're not optimal. You're not optimal.

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Speaker 2: Optimal, Noah, that's right. You want to get towards that

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Speaker 2: top end of the range because that's going to be

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Speaker 2: where you're getting all of those blood sugar and mood

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Speaker 2: and cardiovascular benefits and you've got the benefits on your muscle.

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Speaker 2: So in many if it's early stage, you can just

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Speaker 2: use herbal medicine and DHA. The other big thing is

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Speaker 2: if you want to test your estrogen as well, because

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Speaker 2: if your estrogen levels are going up now that can

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Speaker 2: be related to environmental toxicants, plastics and other things are

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Speaker 2: pushing that up. You need something to block the testosterone

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Speaker 2: getting converted into estrogens, like dim or indole three carbonyl.

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Speaker 2: These are all compounds that come from cruciferous vegetables. So

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Speaker 2: those compounds will help us to maintain the testosterone. So

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Speaker 2: in many cases, those kind of three categories of supplements

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Speaker 2: slash hormones will be enough. Now, in some cases when

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Speaker 2: people just you know, basically the system is failing, they

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Speaker 2: may just have very low testosterone levels, and in that

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Speaker 2: case you may need to then supplement testosterone.

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Speaker 1: I like the way you go to the DHA first,

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Speaker 1: because once somebody goes on to t RT, you've got

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Speaker 1: to be on it. Yeah right, yeah, don't you, because

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Speaker 1: that's it. You're on that tree, and you're on that

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Speaker 1: tree for life and and and you know, for me,

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Speaker 1: it's like I'm going to wait until I can't get

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Speaker 1: it through all my strength training that and then first

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Speaker 1: of all DT and everything that you said, and then

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Speaker 1: t RT at some stage if it drops over, because

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Speaker 1: some people will will get to their eties with reasonable amounts,

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Speaker 1: won't they.

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Speaker 2: Yes, And you know there's other little tricks you can do.

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Speaker 2: Sometimes the h CG program I also help a lot,

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Speaker 2: but yeah, I mean strength exercise for me doubled my

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Speaker 2: test after and levels.

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Speaker 1: So yeah, yeah, Well a brilliant way to increase stress

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Speaker 1: officer and growth. Hormone is the lift heavy ship, really,

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Speaker 1: isn't it. So let's let's go and talk about the female. Now,

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Speaker 1: who's who's going through menopause? What what's your view on

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Speaker 1: on HRT because it's still is a little bit controversial.

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Speaker 1: You'll still have some people say, oh that courses breast

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Speaker 1: counts a risk, But tell us what there is the

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Speaker 1: research actually say, and what do you talk about in

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Speaker 1: your practice.

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Speaker 2: Yeah, So the Women's Health Initiative was a very very

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Speaker 2: large study and it looked at synthetic hormone replacement, particularly

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Speaker 2: what's called premarin, which is pregnant mays urine and Provea,

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Speaker 2: which is a synthetic progesterone. Now, one of the problems

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Speaker 2: with that is synthetic hormones are never going to have

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Speaker 2: exactly the same effect on the human body as bioidentical

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Speaker 2: ones are. So bioidentical means they're the exact same compounds,

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Speaker 2: not just a similar compound. So in the case of

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Speaker 2: PROVEA or other synthetic progesterones or progestogens they're often referred to,

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Speaker 2: they will have the same effect as progesterone in the womb,

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Speaker 2: but in the rest of the body they can actually

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Speaker 2: have the opposite effect, the effect more as estrogen, and

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Speaker 2: therefore these ladies are actually getting a double dose of

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Speaker 2: estrogen in their breasts and so on. So when you

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Speaker 2: think about it, it's actually no wonder. There was a

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Speaker 2: slightly greater risk of breast cancer in some cohorts of

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Speaker 2: that study, and that was one of the biggest findings

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Speaker 2: that raised concern. Now, when we go bio identical, we're

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Speaker 2: not using a synthetic progesterone. We're using actual progesterone, so

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Speaker 2: that should act. It will act in the same way

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Speaker 2: as our own progesterone when it comes to the tissue

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Speaker 2: in the womb or outside the womb. It used to

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Speaker 2: be taught at one point that you only need progesterone

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Speaker 2: if you have a womb.

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Speaker 1: All right, wow, really yeah, yeah, for a long time.

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Speaker 2: I think it still is in many circles and obstetrics

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Speaker 2: and gynecology. So if you're doing hormone replacement. You give

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Speaker 2: estrogen and then you give progesterone if the woman has

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Speaker 2: a WORMB So what about the rest of the body.

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Speaker 2: What on earth? Progesterone is hugely diuretic, it's anti anxiety,

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Speaker 2: it promotes bone health. It has such a diverse range

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Speaker 2: of actions that it's absurd to think of it as

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Speaker 2: only being important for the worm.

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Speaker 1: Yeah, it's only important for the moon. That would only

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Speaker 1: be receptors for it in exactly.

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Speaker 2: Exactly, So, yeah, it's it is. Unfortunately, it's one of

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Speaker 2: those doctrines that is just stuck and nobody's questioned it

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Speaker 2: or not enough people, not enough doctors have questioned it,

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Speaker 2: and so basically bioidentical hormone. The first thing about that

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Speaker 2: therapy is we're trying to find the correct balance. We're

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Speaker 2: trying to give, you know, big doses of hormones and

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Speaker 2: only give progesterone when you have a womb. We're talking

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Speaker 2: about getting the correct ratios of estrogen to progesterone and

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Speaker 2: estrogen to testosterone, et cetera, et cetera. Now that's the

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Speaker 2: key in my view, is that you're looking for the

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Speaker 2: correct ratios of these hormones and not necessarily the levels,

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Speaker 2: but of course the absolute levels will matter to some degree.

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Speaker 2: And so you know, it's quite common that you'll use

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Speaker 2: creams for progesterone, estrogen, and then DHA and testosterone. They

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Speaker 2: are also important for women, not just for men, and progesterone,

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Speaker 2: for that matter, is also important for men. And so

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Speaker 2: quite commonly what you'll find is that women have something

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Speaker 2: called estrogen dominance, where there's too much estrogen relative to progesterone.

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Speaker 2: But once they've gone through menopause, they still may need

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Speaker 2: a small amount of estrogen as well and DHA and

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Speaker 2: other things, but the emphasis is on progesterone. And as

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Speaker 2: a result of that, the studies have been quite reassuring

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Speaker 2: so far.

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Speaker 4: Yeah, problems, and it's highly likely that that is going

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Speaker 4: to lead to much much better longevity than having imbalanced

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Speaker 4: and low levels of those sexual.

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Speaker 1: Modes, and not only longevity, but quality of life. And

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Speaker 1: you know, I know a number of women who've gone

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Speaker 1: on to bioidentical HRT and it has transformed.

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Speaker 2: I mean, sometimes when women go through menopause, they feel

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Speaker 2: like they just don't know themselves anymore. They don't react

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Speaker 2: the way they used to. They're developing much greater anxiety,

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Speaker 2: and it's just like they they've lost the person that

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Speaker 2: they were.

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Speaker 1: Yeah, and it just goes to show the role of

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Speaker 1: hormones in mental health as well, So not just for

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Speaker 1: for females, but for meals. I mean we mentioned it

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Speaker 1: earlier on and most blokes have never heard of andropause.

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Speaker 1: And you know, those those changing hormones when your hit,

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Speaker 1: whether it's your forties year, fifties, whether it is, but

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Speaker 1: it can massively affect your your physical fatality and your

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Speaker 1: mental health as well, right.

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Speaker 2: One hundred percent. I've actually seen seen men crying and

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Speaker 2: then saying, look, there's nothing upsetting me. I simply you know,

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Speaker 2: it's simply my hormones have gone. I've lost the testosterone.

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Speaker 2: You bring that testosterone back in, or you do it

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Speaker 2: through those other methods that we mentioned d h A

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Speaker 2: and herbal medicine, et cetera. And then all of a sudden,

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Speaker 2: you know they're back to an even keel. So there

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Speaker 2: they're definitely, I mean, there definitely is a big role

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Speaker 2: there for restoration of hormone balance. We're not talking for me,

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Speaker 2: it's not talking about crazy levels of hormone.

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Speaker 1: Super physiological Yeah, we don't need that No, that's right.

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Speaker 2: We're not trying to do everything through hormones. We're just

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Speaker 2: trying to get balance.

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Speaker 1: And I think that for me, the the emphasis of hormones,

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Speaker 1: particularly on mental health is I know a number of

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Speaker 1: bodybuilders who have told me that you know, that they

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Speaker 1: were on anapolic steroids and then they came off those

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Speaker 1: anabolic steroids after years on them, and said that for

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Speaker 1: a year, maybe two years, they were an absolute wreck,

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Speaker 1: complete reck mentally emotionally just because of those changing hormones,

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Speaker 1: and it took them a long time before they restabilized.

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Speaker 1: So I think that's a lesson for everybody. Now we've

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Speaker 1: talked about we've talked about the big ones, right, so

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Speaker 1: we've talked about all the chronic diseases, things about that.

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Speaker 1: We've talked about diet, we've talked about that exercise, we

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Speaker 1: talked about sleep, we talked about stress management. We've talked

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Speaker 1: about hormone replacement. You did mention rapamyocin. Maybe let's talk

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Speaker 1: about another couple of classes of maybe pharmaceutical drugs. I

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Speaker 1: just wanted to get your opinion, particularly when we're thinking

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Speaker 1: of you know, the big things the diabetes are metabolic

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Speaker 1: conditions and then cardiovascular what's your view on SGL two

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Speaker 1: inhibitors and PCSK nine inhibitors in terms of maybe a

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Speaker 1: lever to pull around helps.

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Speaker 2: So, yeah, so the PSK inhibitors we're talking about.

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Speaker 1: And maybe explain this far can you explain it for

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Speaker 1: the late people?

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Speaker 2: Well, the PSK inhibitors relate to cholesterol, right, so you're

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Speaker 2: you're looking at not only lowering your cholesterol but also

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Speaker 2: a compound called lipoprotein AM so, so this takes us

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Speaker 2: to cardiovascular health. And so one of the most important

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00:24:06,920 --> 00:24:10,399
Speaker 2: things with cardiovascular health is, as we've discussed before, is

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Speaker 2: getting your metabolic health right. And you know you need

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Speaker 2: to you need to be relatively free of insulance resistance.

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Speaker 2: And you know, one of the simplest ways of measuring

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Speaker 2: that is looking at your waist circumference. Generally want that

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Speaker 2: to be less than around eighty five centimeters and and

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00:24:31,640 --> 00:24:33,680
Speaker 2: so that's very very important. Now on top of that,

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Speaker 2: you want to look at homossysting, you want to look

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Speaker 2: at vitamin D, and you want to look at lip

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Speaker 2: approtein A and then general cholesterol subfractions. I guess so

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Speaker 2: lipid lipid panel, so, lipe approtein A is one that's

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Speaker 2: less known, but it's a combination of a fat and

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Speaker 2: approtein molecule, and some people genetically and also epigenetically, which means,

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Speaker 2: according to you know, the way they're living, tend to

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Speaker 2: run very high levels and that's kind of like an

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Speaker 2: unknown contributor to to athlosclerotic heart disease. So it's very

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Speaker 2: important to look at bringing that down.

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Speaker 1: Now.

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Speaker 2: One of the simplest ways is niosin. However, the studies

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Speaker 2: haven't shown long term benefits in cardiovascular outcomes with the

400
00:25:28,640 --> 00:25:32,359
Speaker 2: use of niosin, so then what has So if you

401
00:25:32,480 --> 00:25:37,119
Speaker 2: just go on a statin medication, that can actually raise

402
00:25:37,240 --> 00:25:43,120
Speaker 2: your levels of LiPo approaching A paradoxically, so that's worth

403
00:25:43,119 --> 00:25:43,800
Speaker 2: being aware of.

404
00:25:43,880 --> 00:25:44,040
Speaker 1: Now.

405
00:25:44,119 --> 00:25:50,399
Speaker 2: PSK inhibitors are a form of injection therapy, and so

406
00:25:51,160 --> 00:25:53,840
Speaker 2: you might inject them once a week or once a month,

407
00:25:54,080 --> 00:25:57,960
Speaker 2: but they reduce generally the LDL cholesterol and the apple

408
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Speaker 2: lipe approaching B which has now been found for be

409
00:26:01,119 --> 00:26:03,119
Speaker 2: the ApoB has been found to be one of the

410
00:26:03,160 --> 00:26:08,640
Speaker 2: most accurate markers, and the lyypoprotein A, so so there

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Speaker 2: does still seem to be some importance of those. Now

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Speaker 2: we know there's many influencers who are going away from

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Speaker 2: this and saying, look forget cholesterol altogether and the sub

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Speaker 2: fractions of those and just get your you know, get

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00:26:22,760 --> 00:26:26,919
Speaker 2: your metabolic health right. Go carnivore for instance. And for

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Speaker 2: some people that may be the case. I have seen

417
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Speaker 2: someone recently who was on a carnivor diet and checked

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00:26:32,240 --> 00:26:34,760
Speaker 2: his current with calcium and it was zero. So it

419
00:26:34,840 --> 00:26:37,320
Speaker 2: may be for some people that that is the case

420
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Speaker 2: that the metabolic health fire outshines anything else. But there

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00:26:42,000 --> 00:26:45,440
Speaker 2: does definitely seem to be cases in which having high

422
00:26:45,560 --> 00:26:50,960
Speaker 2: levels of LDL cholesterol, particularly oxidized LDL or hyperprotein A,

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Speaker 2: can lead to the development of athloscortic heart disease. And

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Speaker 2: so PSK inhibitors are just a class of drugs that

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Speaker 2: can be utilized. They're generally prescribed by cardiologists, but they

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00:27:02,920 --> 00:27:05,920
Speaker 2: can be prescribed by by someone like me as well.

427
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Speaker 2: But that can be a very useful strategy to try

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Speaker 2: and to keep all of those markers well. On the

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Speaker 2: lipid side of things, we still have to work on

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Speaker 2: the vitamin D, we still have to work on the

431
00:27:18,600 --> 00:27:22,280
Speaker 2: home assystem. We still have to work on CRP as well,

432
00:27:22,520 --> 00:27:25,600
Speaker 2: which is to do with inflammation. So there's I guess

433
00:27:25,600 --> 00:27:27,840
Speaker 2: you could say it is a much more broad way

434
00:27:27,880 --> 00:27:31,680
Speaker 2: of looking at cardiovascular disease. But if needed, these class

435
00:27:31,680 --> 00:27:35,040
Speaker 2: of medications can be used to keep that lipid side

436
00:27:35,040 --> 00:27:36,200
Speaker 2: of things under control.

437
00:27:37,160 --> 00:27:39,879
Speaker 1: Yeah, And I think people need to realize that the

438
00:27:40,280 --> 00:27:45,000
Speaker 1: old cholesterol testing, you know, that's a mass population mass

439
00:27:45,040 --> 00:27:50,320
Speaker 1: screening based on pretty flimsy evidence. You know, you've just

440
00:27:50,359 --> 00:27:54,000
Speaker 1: talked about things that are much more impactful than your

441
00:27:54,040 --> 00:27:57,600
Speaker 1: tall cholesterol or your LDL cholesterol, right, you know that

442
00:27:57,640 --> 00:28:00,760
Speaker 1: doesn't tell you about the particle sizes, doesn't tell you

443
00:28:00,800 --> 00:28:04,440
Speaker 1: about other things that that we nine or are increasingly important.

444
00:28:05,960 --> 00:28:10,240
Speaker 1: Let's switch over and talk about metabolic health and and

445
00:28:10,680 --> 00:28:14,680
Speaker 1: SGL two inhibitors. What's your view on on on the

446
00:28:14,800 --> 00:28:18,879
Speaker 1: use of that as a maybe, Well, obviously if somebody

447
00:28:18,920 --> 00:28:21,399
Speaker 1: has got an issue with their insulin and their blood sugar,

448
00:28:21,840 --> 00:28:26,840
Speaker 1: and that's one use KISS, but another use KISS around

449
00:28:26,920 --> 00:28:30,840
Speaker 1: getting your controlling your insulin and getting your blood sugar

450
00:28:30,920 --> 00:28:34,440
Speaker 1: to optimal. Do you think there is a use KISS

451
00:28:34,520 --> 00:28:38,320
Speaker 1: for that in from a longevity health spun perspective.

452
00:28:37,840 --> 00:28:40,880
Speaker 2: Yeah, so you're referring to like semi gluetide and living

453
00:28:40,920 --> 00:28:43,200
Speaker 2: glue tided. Okay, cool, cool, cool. I wasn't sure they're

454
00:28:43,200 --> 00:28:48,600
Speaker 2: for second So yes, those those class of medications. So

455
00:28:48,720 --> 00:28:51,960
Speaker 2: semi glue tide is you know, it's become become the

456
00:28:52,440 --> 00:28:55,080
Speaker 2: fad drug, I guess you could say now. And it's

457
00:28:55,120 --> 00:28:58,600
Speaker 2: been used for weight loss all around the world now

458
00:28:58,680 --> 00:29:02,680
Speaker 2: and if you're you know, celebrity in Hollywood, it's pretty

459
00:29:02,800 --> 00:29:08,200
Speaker 2: likely you're taking it. But you know, and it's not

460
00:29:08,360 --> 00:29:12,920
Speaker 2: without any risks whatsoever, these kind of compounds, So semaglue

461
00:29:12,960 --> 00:29:16,280
Speaker 2: tide is one of the most common. Then we have monjarro,

462
00:29:16,840 --> 00:29:21,160
Speaker 2: which is it's a combination of working on two different

463
00:29:21,280 --> 00:29:25,880
Speaker 2: receptor syites. Now, they do appear to for some people

464
00:29:26,400 --> 00:29:30,760
Speaker 2: they can just start the process of weight loss. Some people,

465
00:29:31,000 --> 00:29:37,800
Speaker 2: even despite changing their diet and exercising very diligently, their

466
00:29:37,880 --> 00:29:41,280
Speaker 2: weight may not shift. And one of the reasons can

467
00:29:41,320 --> 00:29:45,160
Speaker 2: be due to a hormone called leptin, and leptin is

468
00:29:45,480 --> 00:29:51,080
Speaker 2: a hormone produced in the hypothalamus and when again, just

469
00:29:51,160 --> 00:29:55,360
Speaker 2: like the insulin resistance, you can develop leptin resistance where

470
00:29:55,400 --> 00:29:58,480
Speaker 2: the body is not really sensitive to the effects of

471
00:29:58,520 --> 00:30:03,760
Speaker 2: this hormone anymore, and therefore exercise and diet may not work.

472
00:30:03,880 --> 00:30:06,120
Speaker 2: So what we need to do along with the diet

473
00:30:06,160 --> 00:30:10,640
Speaker 2: and the exercise is give something that's going to unblock

474
00:30:10,760 --> 00:30:14,920
Speaker 2: the leptin receptor. Now, other things like intermittent fasting, all

475
00:30:14,960 --> 00:30:20,760
Speaker 2: of that's still really important. Avoiding nighttime eating altogether is

476
00:30:20,800 --> 00:30:24,640
Speaker 2: apparently very very important, and left and resistance. But even

477
00:30:24,680 --> 00:30:28,640
Speaker 2: just bringing in like a microdose of semiglutide or manjarro

478
00:30:29,320 --> 00:30:32,520
Speaker 2: or whatever it is, it can it can help people

479
00:30:32,600 --> 00:30:36,720
Speaker 2: to just to start the process of weight loss. Now

480
00:30:37,160 --> 00:30:39,720
Speaker 2: they've got to continue that through their lifestyle. Of course,

481
00:30:39,720 --> 00:30:42,760
Speaker 2: it's no good stopping them and then the weight rebounding

482
00:30:42,840 --> 00:30:46,200
Speaker 2: back up again. So you know, there's also been some

483
00:30:46,240 --> 00:30:50,880
Speaker 2: studies looking at those kind of medications plus HDG at

484
00:30:50,920 --> 00:30:54,760
Speaker 2: the same time being very useful for weight loss. So

485
00:30:55,080 --> 00:30:57,720
Speaker 2: I guess where we're going here with this discussion is

486
00:30:57,760 --> 00:31:01,320
Speaker 2: that excessive weight is going to get in your way

487
00:31:01,360 --> 00:31:06,040
Speaker 2: of longevity, and excessive insulin resistance, left and resistance, et cetera.

488
00:31:06,160 --> 00:31:10,680
Speaker 2: They are all blocks to having ideal longevity. And so

489
00:31:10,720 --> 00:31:14,160
Speaker 2: the first thing is to identify that you have these

490
00:31:14,200 --> 00:31:20,280
Speaker 2: problems and then exploring the different possible strategies. Sometimes just

491
00:31:20,440 --> 00:31:23,640
Speaker 2: good old met Foreman can be very useful for people.

492
00:31:24,800 --> 00:31:27,440
Speaker 2: One downside to met forman is if you take it

493
00:31:27,480 --> 00:31:31,880
Speaker 2: before a big workout, you can inhibit effect. So what

494
00:31:32,000 --> 00:31:34,080
Speaker 2: I do I don't I don't exercise, I don't do

495
00:31:34,120 --> 00:31:37,200
Speaker 2: a big workout every day. I take met forman on

496
00:31:37,280 --> 00:31:41,080
Speaker 2: the days I don't work out, So that can be

497
00:31:41,160 --> 00:31:44,080
Speaker 2: that can be quite a good strategy. That's often a

498
00:31:44,080 --> 00:31:47,800
Speaker 2: first more like a starting point to you know, to

499
00:31:47,960 --> 00:31:51,400
Speaker 2: help with insulin resistance and wait, and then you might

500
00:31:51,520 --> 00:31:56,520
Speaker 2: then progress to things like the semaglutide, manjaro, HGG, et cetera.

501
00:31:56,920 --> 00:32:00,160
Speaker 2: But I'm not against using these kinds of tools to

502
00:32:00,200 --> 00:32:04,120
Speaker 2: help us to achieve the goals that we're looking for.

503
00:32:05,080 --> 00:32:08,320
Speaker 1: Yeah, yeah, And I guess there's other things. You know,

504
00:32:08,320 --> 00:32:10,440
Speaker 1: you've got met form and you mentioned there's things like

505
00:32:10,600 --> 00:32:17,560
Speaker 1: for zayga, what's that's a life losing Yeah, which is

506
00:32:17,560 --> 00:32:20,880
Speaker 1: is less extreme than than the manjaro and those sorts

507
00:32:20,880 --> 00:32:24,440
Speaker 1: of things, but can can actually help control that without

508
00:32:25,000 --> 00:32:27,720
Speaker 1: some of the side effects of these other drugs, because

509
00:32:28,040 --> 00:32:31,400
Speaker 1: I think educating people that when they when they take

510
00:32:31,680 --> 00:32:35,600
Speaker 1: these these amazing weight loss drugs, they lose a shipload

511
00:32:35,600 --> 00:32:39,640
Speaker 1: of muscle as well as that, which is not good. Interesting.

512
00:32:39,640 --> 00:32:41,440
Speaker 1: I don't know if you've seen tan san deep the

513
00:32:41,440 --> 00:32:45,320
Speaker 1: the recent clinical trials where they've added in a mile

514
00:32:45,480 --> 00:32:50,280
Speaker 1: statin blocker into this. So maya statn is the it's

515
00:32:50,360 --> 00:32:53,560
Speaker 1: the one mile kind that inhibits muscle growth. And so

516
00:32:53,640 --> 00:32:57,240
Speaker 1: when they block that, the people that were taking the

517
00:32:57,360 --> 00:33:01,080
Speaker 1: myostatin blocker with the that was the version of manjar

518
00:33:01,200 --> 00:33:04,680
Speaker 1: or whatever, we're losing weir it but preserving muscle.

519
00:33:05,840 --> 00:33:09,240
Speaker 2: Okay, yeah, it's very interesting.

520
00:33:09,720 --> 00:33:11,760
Speaker 1: It is very interesting because I was talking to someone,

521
00:33:11,880 --> 00:33:14,440
Speaker 1: I said, you know, they're going to start adding in

522
00:33:14,640 --> 00:33:19,960
Speaker 1: malekines to these things. I wasn't expecting them to work

523
00:33:20,000 --> 00:33:22,920
Speaker 1: on my statin, but once I thought, Jesus, that makes

524
00:33:22,920 --> 00:33:26,480
Speaker 1: a lot of sense. And so that's an interesting next

525
00:33:26,560 --> 00:33:30,000
Speaker 1: generation of these drugs that's actually coming out.

526
00:33:30,160 --> 00:33:35,120
Speaker 2: But we're talking about the field of precision medicine really,

527
00:33:35,200 --> 00:33:39,720
Speaker 2: where we're using using medications in a much more targeted

528
00:33:40,200 --> 00:33:43,920
Speaker 2: fashion rather than just using them, you know, using it

529
00:33:43,920 --> 00:33:46,120
Speaker 2: as a road thing. Okay, you've got high cholesterol, here's

530
00:33:46,160 --> 00:33:49,200
Speaker 2: your stat and we're trying to use it in a

531
00:33:49,320 --> 00:33:53,600
Speaker 2: much more precise way to achieve longevity goals.

532
00:33:54,680 --> 00:33:58,320
Speaker 1: Now, what's your I was just asking your opinion on

533
00:34:00,120 --> 00:34:06,040
Speaker 1: men an are and these sorts that that you see everywhere, right,

534
00:34:06,640 --> 00:34:13,040
Speaker 1: particularly influencers promoting them. And you know, the theory is

535
00:34:13,040 --> 00:34:16,680
Speaker 1: is reasonably signed, like an E D is really critical

536
00:34:16,760 --> 00:34:19,000
Speaker 1: as we it is we drop an E D and

537
00:34:19,040 --> 00:34:23,640
Speaker 1: that's that that's important. You know, it impacts on our energy.

538
00:34:23,880 --> 00:34:27,799
Speaker 1: And there are some studies showing that these molecules can

539
00:34:27,960 --> 00:34:32,080
Speaker 1: increase an A D. What I haven't yet seen is

540
00:34:32,120 --> 00:34:35,080
Speaker 1: obviously impacts on longevity. But where where do you sit

541
00:34:35,160 --> 00:34:38,400
Speaker 1: on it? Because I'm a little bit on the fence

542
00:34:38,520 --> 00:34:41,040
Speaker 1: until I see some more data come out. But you may,

543
00:34:41,120 --> 00:34:43,880
Speaker 1: you may, you may have a different view on it.

544
00:34:44,280 --> 00:34:47,040
Speaker 2: Well, I think they come under the broader category of

545
00:34:47,120 --> 00:34:51,040
Speaker 2: mitochondrial support, and so I think it's important to know

546
00:34:51,120 --> 00:34:54,719
Speaker 2: that mitochondria is not just about an A D. There's

547
00:34:54,880 --> 00:34:58,480
Speaker 2: you know, there's there's much more to mitochondria and and

548
00:34:58,520 --> 00:35:00,800
Speaker 2: there's many things we can be doing in our daily

549
00:35:00,880 --> 00:35:04,160
Speaker 2: life which are you could say they're all longevity promoters

550
00:35:04,440 --> 00:35:08,359
Speaker 2: that assist the mitochondria. So we're doing saunas regularly, we're

551
00:35:08,360 --> 00:35:13,160
Speaker 2: doing ice baths, we're doing intermittent fasting, red light therapy,

552
00:35:13,680 --> 00:35:17,520
Speaker 2: hyperbaric all of those things are going to help the mitochondria.

553
00:35:17,640 --> 00:35:21,000
Speaker 2: Hydrogen water. That's one of the recents that also seems

554
00:35:21,040 --> 00:35:25,280
Speaker 2: to help the mitochondria very much. Now NAD My approach

555
00:35:25,320 --> 00:35:29,839
Speaker 2: to this is, why wouldn't you check your levels? You know?

556
00:35:29,960 --> 00:35:34,000
Speaker 2: And so I do NAD testing. It's a blood spot test,

557
00:35:34,120 --> 00:35:38,640
Speaker 2: just like the true age, and you find out your levels. Now,

558
00:35:39,239 --> 00:35:44,000
Speaker 2: so far everyone except myself and one other has been low.

559
00:35:44,800 --> 00:35:46,880
Speaker 2: And the difference of why am I the difference, Well,

560
00:35:46,880 --> 00:35:51,879
Speaker 2: I've taken a lot, so it probably does come down

561
00:35:51,920 --> 00:35:57,359
Speaker 2: to supplementation at this point, you take it a lot.

562
00:35:57,600 --> 00:36:01,680
Speaker 2: I've taken R well, no I an NAD IV. I'll

563
00:36:01,760 --> 00:36:06,440
Speaker 2: take some NMN as well orally. So my approach is

564
00:36:06,560 --> 00:36:11,719
Speaker 2: usually starting with more injectable forms if someone's low, and

565
00:36:12,320 --> 00:36:15,640
Speaker 2: then then seeing if they can, you know, getting their

566
00:36:15,719 --> 00:36:18,279
Speaker 2: levels up, and then seeing if they can maintain them

567
00:36:18,600 --> 00:36:21,600
Speaker 2: with precursors. I don't think it's quite as easy, and

568
00:36:21,640 --> 00:36:26,600
Speaker 2: I think some people may not convert convert the precursors efficiently,

569
00:36:27,160 --> 00:36:30,960
Speaker 2: and it's you know, there's no way to know until

570
00:36:31,000 --> 00:36:35,480
Speaker 2: you just do an experiment. Do an experiment, find out. Okay,

571
00:36:35,840 --> 00:36:38,319
Speaker 2: let's do NMN, or even let's say someone's very low

572
00:36:38,360 --> 00:36:40,439
Speaker 2: and they just want to start with NMN. They don't

573
00:36:40,440 --> 00:36:43,400
Speaker 2: want to do any injections, no problems. Take a certain

574
00:36:43,400 --> 00:36:46,360
Speaker 2: amount for three or six months, and then we'll recheck

575
00:36:46,400 --> 00:36:48,840
Speaker 2: your levels and let's see if it has made a

576
00:36:48,880 --> 00:36:49,880
Speaker 2: meaningful difference.

577
00:36:50,440 --> 00:36:52,520
Speaker 1: And I didn't know you could do blood spot testing

578
00:36:52,600 --> 00:36:53,280
Speaker 1: of ND.

579
00:36:53,320 --> 00:36:56,160
Speaker 2: That's interesting, it's actually, yeah, I think. And it looks

580
00:36:56,200 --> 00:36:58,560
Speaker 2: at a number of the different ratios as well, like

581
00:36:58,640 --> 00:37:01,440
Speaker 2: the NA D to n A d H ratio and

582
00:37:01,480 --> 00:37:04,680
Speaker 2: the n A D n A d p H ratio

583
00:37:04,760 --> 00:37:08,080
Speaker 2: which is actually very much related to blood sugar control

584
00:37:08,840 --> 00:37:11,200
Speaker 2: m hm. So I am finding that to be That's

585
00:37:11,239 --> 00:37:14,919
Speaker 2: another test that we do routinely. We also do the hormones,

586
00:37:15,040 --> 00:37:18,840
Speaker 2: as you suggested, a wide range of nutrients on people,

587
00:37:19,320 --> 00:37:24,120
Speaker 2: and then hair mineral analysis. It's actually quite important, I

588
00:37:24,160 --> 00:37:27,040
Speaker 2: believe just looking at the minerals in the in the

589
00:37:27,080 --> 00:37:30,600
Speaker 2: body as being an important determinant of longevity.

590
00:37:30,640 --> 00:37:33,680
Speaker 1: Because your hair is a is a more long standing

591
00:37:33,840 --> 00:37:37,400
Speaker 1: marker then getting blood, isn't it, because it it's pretty

592
00:37:37,440 --> 00:37:40,680
Speaker 1: transient in blood, but it stays in her exactly. I'm

593
00:37:40,680 --> 00:37:43,360
Speaker 1: a bit I'm a bit challenged in that department.

594
00:37:42,920 --> 00:37:45,640
Speaker 2: But well, you've got hair elsewhere.

595
00:37:46,120 --> 00:37:47,000
Speaker 1: Yeah, that's right.

596
00:37:47,840 --> 00:37:48,360
Speaker 2: That gets me.

597
00:37:48,480 --> 00:37:52,440
Speaker 3: Used, so it's it's a more long term marker. It's

598
00:37:52,440 --> 00:37:56,640
Speaker 3: a marker of tissue levels and uh. And there's various

599
00:37:56,680 --> 00:37:59,560
Speaker 3: patterns that can show up in the hair that may

600
00:37:59,600 --> 00:38:00,960
Speaker 3: well not sharp in the blood.

601
00:38:01,080 --> 00:38:04,000
Speaker 2: So if you're really depleted, and if you're in like

602
00:38:04,040 --> 00:38:07,520
Speaker 2: a collapse pattern and there are certain patterns on hammer

603
00:38:07,640 --> 00:38:11,279
Speaker 2: or analysis that suggest that, then you may need to

604
00:38:11,440 --> 00:38:14,120
Speaker 2: just focus on building your body up and actually not

605
00:38:14,280 --> 00:38:18,239
Speaker 2: going to heavy exercise straight away. So there can be

606
00:38:18,320 --> 00:38:21,000
Speaker 2: little variations like if you're too I don't know what

607
00:38:21,040 --> 00:38:23,400
Speaker 2: your view on this is, but if you're totally burnt

608
00:38:23,440 --> 00:38:27,160
Speaker 2: out adrenally and so on, you know, yeah, you know

609
00:38:27,239 --> 00:38:29,920
Speaker 2: you may not recovered. Yeah, you've got to recover before

610
00:38:30,000 --> 00:38:32,320
Speaker 2: you can start doing really really.

611
00:38:32,080 --> 00:38:37,759
Speaker 1: Heavy Yeah, absolutely, yeah, absolutely yeah. Whenever you're in the hole,

612
00:38:37,800 --> 00:38:39,560
Speaker 1: you've got to get yourself out of the hole before

613
00:38:39,600 --> 00:38:44,400
Speaker 1: you start to optimize. But the last couple of questions

614
00:38:44,960 --> 00:38:52,080
Speaker 1: I'm aware of your time is heavy metals, heavy metals

615
00:38:52,080 --> 00:38:56,280
Speaker 1: in the body, testing for them, do you find it useful?

616
00:38:56,640 --> 00:39:00,480
Speaker 1: And then if you find that people do have presence

617
00:39:00,480 --> 00:39:03,719
Speaker 1: of heavy metals, what's the appropriate intervention.

618
00:39:04,680 --> 00:39:08,319
Speaker 2: I feel I do feel heavy metals are very important firstly, yes,

619
00:39:08,360 --> 00:39:13,080
Speaker 2: and they are very important biochemical disruptors, and so the

620
00:39:13,120 --> 00:39:19,400
Speaker 2: basic concept is that they will replace nutritional medicine metals

621
00:39:19,520 --> 00:39:24,600
Speaker 2: rather such as zinc and selenium and many many others

622
00:39:25,640 --> 00:39:31,160
Speaker 2: in enzyme binding sites. So basically those nutrients are vital

623
00:39:31,239 --> 00:39:36,600
Speaker 2: for enzymes working. Enzymes are like biological catalysts of reactions

624
00:39:36,600 --> 00:39:40,080
Speaker 2: in the body. So if you have if you have

625
00:39:40,120 --> 00:39:44,080
Speaker 2: an enzyme that's dependent on zinc and you have a

626
00:39:44,080 --> 00:39:47,439
Speaker 2: heap of cadmium from smoking in the past, then that

627
00:39:47,480 --> 00:39:49,960
Speaker 2: cadmium will go and replace the zinc, and that enzyme

628
00:39:50,080 --> 00:39:54,080
Speaker 2: might only work at thirty percent. Well, that doesn't sound

629
00:39:54,120 --> 00:39:55,520
Speaker 2: like it's going to help you to get to your

630
00:39:55,560 --> 00:39:59,359
Speaker 2: longevity goals, does it. So it's important to know that

631
00:39:59,480 --> 00:40:02,840
Speaker 2: these pounds in the body. I'll also add micotoxins to

632
00:40:02,920 --> 00:40:06,400
Speaker 2: that list. If you've got mold toxins in the body,

633
00:40:06,520 --> 00:40:10,200
Speaker 2: that's also going to greatly affect things, you know, chemicals

634
00:40:10,760 --> 00:40:13,799
Speaker 2: probably as well. So you need to identify them.

635
00:40:13,800 --> 00:40:13,960
Speaker 1: Now.

636
00:40:14,000 --> 00:40:17,319
Speaker 2: One of the simplest ways is doing hair mineral analysis.

637
00:40:18,160 --> 00:40:18,399
Speaker 1: Now.

638
00:40:18,560 --> 00:40:20,919
Speaker 2: The thing you need to know though is they may

639
00:40:20,960 --> 00:40:24,919
Speaker 2: not show up on the first analysis, and you may

640
00:40:25,360 --> 00:40:27,879
Speaker 2: and they've really you've got to come from the fundamental

641
00:40:27,880 --> 00:40:33,000
Speaker 2: assumption that everyone has a degree of heavy metals.

642
00:40:32,960 --> 00:40:35,839
Speaker 1: If you've been on this planet for a while, a

643
00:40:35,880 --> 00:40:37,080
Speaker 1: strong likelihood in there.

644
00:40:37,160 --> 00:40:39,800
Speaker 2: Yeah, that's right. I had quite a lot of mercury myself.

645
00:40:39,880 --> 00:40:42,640
Speaker 2: I had some cadmium. I've had some aluminium, very high

646
00:40:42,719 --> 00:40:46,239
Speaker 2: levels of aluminum, so, you know, and that's not from

647
00:40:46,320 --> 00:40:50,200
Speaker 2: doing anything really crazy, it's just from living on this planet.

648
00:40:50,320 --> 00:40:53,760
Speaker 2: So most so, basically, I think everyone has some degree

649
00:40:53,800 --> 00:40:57,240
Speaker 2: of heavy metals, and everyone needs to build up their minerals.

650
00:40:57,239 --> 00:41:01,080
Speaker 2: Everyone's somewhat deplete in minerals. So the first step actually

651
00:41:01,080 --> 00:41:03,640
Speaker 2: with heavy metals is to build up your mineral reserves

652
00:41:03,960 --> 00:41:08,879
Speaker 2: and your your antioxidant and reserves, and your detoxification capacity,

653
00:41:09,440 --> 00:41:13,560
Speaker 2: and then too, you know, sometimes to then assist the

654
00:41:13,600 --> 00:41:19,080
Speaker 2: detoxification systems to rid heavy metals from the body. Whether

655
00:41:19,120 --> 00:41:25,000
Speaker 2: that's using things like coriander and chlrella, et cetera, or

656
00:41:25,160 --> 00:41:27,680
Speaker 2: you know, there's many many other approaches. Some people use

657
00:41:27,760 --> 00:41:30,600
Speaker 2: d m s A et cetera, et cetera, or some

658
00:41:30,640 --> 00:41:35,880
Speaker 2: people are more fans of just doing detoxication procedures really regularly,

659
00:41:35,960 --> 00:41:38,160
Speaker 2: like saunas and coffee animals.

660
00:41:37,719 --> 00:41:44,960
Speaker 1: And charcoal and sweat, and you gotta you gotta sweat, right,

661
00:41:45,600 --> 00:41:49,800
Speaker 1: sweat that stuff, lots of cruciferous vegetables, lots of onion

662
00:41:49,840 --> 00:41:53,360
Speaker 1: sky like click, fears one and fears two, detox pathways.

663
00:41:52,920 --> 00:41:56,000
Speaker 2: Right, exactly right, So look, I do think it's very

664
00:41:56,040 --> 00:41:59,799
Speaker 2: important to know there are also more specific tests for it,

665
00:42:00,640 --> 00:42:04,439
Speaker 2: which we call urinary provocation tests. It's not done as

666
00:42:04,480 --> 00:42:07,080
Speaker 2: commonly anymore, but I certainly have used those tests and

667
00:42:07,160 --> 00:42:10,279
Speaker 2: they can be very useful at times. And you know,

668
00:42:10,360 --> 00:42:13,319
Speaker 2: people can if they've got very high levels or they're

669
00:42:13,360 --> 00:42:15,920
Speaker 2: being affected by the heavy metal. So for instance, let's

670
00:42:15,920 --> 00:42:18,080
Speaker 2: say you've got a lot of lead and you've got

671
00:42:18,120 --> 00:42:21,080
Speaker 2: cardiovascular disease, Well you might want to do something called

672
00:42:21,120 --> 00:42:26,600
Speaker 2: et aculation IV, which can help you to rid your

673
00:42:26,600 --> 00:42:29,560
Speaker 2: body of the lead and just to help your your circulation.

674
00:42:31,080 --> 00:42:37,840
Speaker 1: Very cool. And last question, what is either the biggest

675
00:42:38,080 --> 00:42:42,280
Speaker 1: anti longevity habit that you see in people or or

676
00:42:42,400 --> 00:42:45,960
Speaker 1: or what would be the one thing that you would

677
00:42:45,960 --> 00:42:48,800
Speaker 1: say to people to do less of or to stop

678
00:42:48,920 --> 00:42:51,520
Speaker 1: doing In terms of longevi we've been talking about lots

679
00:42:51,520 --> 00:42:54,239
Speaker 1: of things that we should do. What should we be

680
00:42:54,560 --> 00:42:57,160
Speaker 1: stopping doing or doing a shitload less.

681
00:42:56,920 --> 00:42:59,000
Speaker 2: Of Okay, some of you may not like me for

682
00:42:59,080 --> 00:43:02,840
Speaker 2: this that I think. My answer is just drinking copious

683
00:43:02,880 --> 00:43:08,280
Speaker 2: amounts of alcohol. It is probably the biggest anti anti

684
00:43:08,320 --> 00:43:10,840
Speaker 2: longevity habit. And you know, of course, we all like

685
00:43:10,880 --> 00:43:14,200
Speaker 2: to have fun, and we're not saying don't have fun,

686
00:43:14,719 --> 00:43:18,080
Speaker 2: but if it becomes like a habit, you know where

687
00:43:18,120 --> 00:43:22,000
Speaker 2: you're you're having four, five, six, seven alcoholic drinks a night.

688
00:43:22,040 --> 00:43:23,680
Speaker 2: And I think a lot of people who are under

689
00:43:23,719 --> 00:43:28,239
Speaker 2: pressure CEOs, et cetera, you know, because they may not

690
00:43:28,400 --> 00:43:33,040
Speaker 2: have time to find other strategies, tend to adopt this

691
00:43:33,120 --> 00:43:36,759
Speaker 2: habit of just drinking very, very large amounts of alcohol.

692
00:43:37,120 --> 00:43:39,600
Speaker 2: I think that is going to cause problems when it

693
00:43:39,600 --> 00:43:43,279
Speaker 2: comes to longevity. I think, yeah, I think it's it's

694
00:43:43,360 --> 00:43:48,840
Speaker 2: going to inhibit many of those helpful biochemical pathways, and.

695
00:43:48,719 --> 00:43:53,080
Speaker 1: So I screw up your metabolic health at the same time.

696
00:43:53,200 --> 00:43:56,160
Speaker 2: Exactly, that's right. So you know, I would say, try

697
00:43:56,200 --> 00:44:01,919
Speaker 2: to get high on life without all the alcohol. Try

698
00:44:01,960 --> 00:44:06,000
Speaker 2: and just get high through you know, connection, through getting

699
00:44:06,000 --> 00:44:09,800
Speaker 2: into nature, through you know, being in connection with wonderful people,

700
00:44:09,920 --> 00:44:14,560
Speaker 2: through exploring new interests, you know, through all those variety

701
00:44:14,600 --> 00:44:16,840
Speaker 2: of means. Try to just be high on life. We

702
00:44:16,880 --> 00:44:19,879
Speaker 2: all want to be happy, of course, but we need

703
00:44:19,920 --> 00:44:22,960
Speaker 2: to find a more holistic way. I think of trying

704
00:44:22,960 --> 00:44:25,680
Speaker 2: to find that happiness rather than just through alcohol.

705
00:44:26,480 --> 00:44:28,360
Speaker 1: Yeah, if you if your happiness is in a bottle,

706
00:44:28,400 --> 00:44:29,440
Speaker 1: that's probably not a good thing.

707
00:44:31,280 --> 00:44:33,319
Speaker 2: That's a good This has.

708
00:44:33,239 --> 00:44:37,760
Speaker 1: Been awesome And now you do run longevity programs. Yes,

709
00:44:37,880 --> 00:44:42,040
Speaker 1: so we're where do we send people to find out

710
00:44:42,080 --> 00:44:45,920
Speaker 1: more about your longevity program if they're interested in increasing

711
00:44:45,960 --> 00:44:48,279
Speaker 1: their health spun and potentially their life spun.

712
00:44:48,440 --> 00:44:51,239
Speaker 2: Yeah, if you go to our website, it's Lotus Holistic

713
00:44:51,440 --> 00:44:54,840
Speaker 2: Medicine dot com dot au. So there's no w in

714
00:44:54,880 --> 00:44:57,279
Speaker 2: the holistic just hate your well is s t I

715
00:44:57,320 --> 00:45:01,319
Speaker 2: C so Lotus Holistic Medicine dot com dot au. And

716
00:45:01,360 --> 00:45:04,279
Speaker 2: if you just click on longevity, you'll see that there

717
00:45:04,360 --> 00:45:08,720
Speaker 2: is a there is a button there to organize a

718
00:45:08,719 --> 00:45:11,000
Speaker 2: discovery call with one of our health coaches and we

719
00:45:11,040 --> 00:45:13,840
Speaker 2: can chat with you about whether it's right for you

720
00:45:13,960 --> 00:45:16,200
Speaker 2: or not, because you know, it's not right for everyone

721
00:45:16,280 --> 00:45:19,880
Speaker 2: if you're not at the stage in your life journey

722
00:45:19,880 --> 00:45:22,960
Speaker 2: where you can invest on all levels, like there's a

723
00:45:22,960 --> 00:45:24,960
Speaker 2: bit of a you know, there's there's an investment of

724
00:45:25,080 --> 00:45:28,359
Speaker 2: energy there's an investment of money as well, and so yeah,

725
00:45:28,440 --> 00:45:30,719
Speaker 2: if you're at that stage and you you know you

726
00:45:30,800 --> 00:45:32,640
Speaker 2: really want to do it. I myself, I'm doing a

727
00:45:32,640 --> 00:45:35,600
Speaker 2: long devity program at the moment and loving it and

728
00:45:36,320 --> 00:45:40,000
Speaker 2: looking at doing my next true age test in February

729
00:45:40,040 --> 00:45:44,200
Speaker 2: next year and trying to get my biological age down

730
00:45:44,719 --> 00:45:46,440
Speaker 2: more and more. So if you want to join me

731
00:45:46,520 --> 00:45:50,759
Speaker 2: on this fun adventure, yeah, come and chat with one

732
00:45:50,800 --> 00:45:52,520
Speaker 2: of our health coaches and what we'll let you know

733
00:45:52,560 --> 00:45:53,240
Speaker 2: what's involved.

734
00:45:54,040 --> 00:45:58,000
Speaker 1: Awesome, Sandy cooped up. Thank you very much. Keep doing

735
00:45:58,040 --> 00:46:01,120
Speaker 1: what you're doing and and and good for us all

736
00:46:01,200 --> 00:46:04,319
Speaker 1: that you manage to get out of the traditional and

737
00:46:04,520 --> 00:46:05,400
Speaker 1: sick cour system.

738
00:46:06,160 --> 00:46:08,279
Speaker 2: Thank you, Paul. It's been a pleasure chatting with you

739
00:46:08,400 --> 00:46:11,840
Speaker 2: and also hearing some of your amazing knowledge. So thank you,

740
00:46:11,880 --> 00:46:14,160
Speaker 2: and you please keep doing what you're doing too. It

741
00:46:14,280 --> 00:46:17,520
Speaker 2: was very inspired by your talk at ACNAM last year.

742
00:46:18,160 --> 00:46:31,200
Speaker 1: Oh cool, excellent good stuff. Thanks Matte