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Speaker 1: Hey, everybody, welcome to another edition of Wisdom Wednesdays. Today,

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Speaker 1: I want to talk about something that we can do

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Speaker 1: that will actually help to reset our immune system, give

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Speaker 1: us a cellular spring clean and potentially reset autoimmune conditions.

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Speaker 1: So let's first of we talk about your immune system.

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Speaker 1: So you'll all know, this is your body's defense system

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Speaker 1: against things such as bacteria, parasites, viruses, toxins, and other things.

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Speaker 1: And in order for it to function properly, it needs

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Speaker 1: the support of a healthy diet and lifestyle practices, which

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Speaker 1: can include fasting. Now, many of us engage in lifestyle

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Speaker 1: practices that are really not ideal, but according to research,

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Speaker 1: embarking on a three day or more water fast can

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Speaker 1: reset your immune system and make an enormous difference to

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Speaker 1: your health. So, according to a study published in twenty

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Speaker 1: nineteen in the journal Sale and Stem Cell Research, prolonged

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Speaker 1: fasting lasting anywhere from forty eight to one hundred and

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Speaker 1: twenty rs so five days can benefit your immune system

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Speaker 1: and activate pathways that enhance resistance to toxins and stress.

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Speaker 1: So both studies on nice and human trials on chemotherapy

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Speaker 1: patients both suggest that a period of fasting can significantly

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Speaker 1: lower white blood cell count, and fasting may help to

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Speaker 1: activate regeneration and signal pathways to matopoetic stem cells that

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Speaker 1: all the generation of blood and a healthy immune system.

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Speaker 1: So what's happening is that during the time that you're fasting,

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Speaker 1: your body is obviously trying to see of energy, and

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Speaker 1: in order to do that, it ends up recycling old

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Speaker 1: and damaged immune cells and other cells such as sinescent cells,

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Speaker 1: which are kind of like zombie cells. And it also

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Speaker 1: does a recycling of broken or dysfunctional parts within a cell.

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Speaker 1: And this is known as autophogy. So you can have

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Speaker 1: autopogy within the cell and then you can have system

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Speaker 1: wide autopogy. So the study that I mentioned earlier on

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Speaker 1: found that fasting can also lower IGF one and growth

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Speaker 1: hormone levels that when they are consistently high, have been

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Speaker 1: linked to cancer and tumor growth and accelerated aging. Now,

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Speaker 1: these findings support previous research by Volter Longos group and

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Speaker 1: others that report that fasting in chemotherapy appears to be

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Speaker 1: significantly more effective than chemotherapy alone. So fasting in the

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Speaker 1: seventy two hours before chemotherapy and appeared to boost the

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Speaker 1: immune system and benefit CHEMEO therapy patients in that they

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Speaker 1: had protection, their normal sales were protected against the damage.

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Speaker 1: But also what happens was they had less side effects

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Speaker 1: from the chemo therapy. And I personally have a good

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Speaker 1: mate who used this approach, not only the fasting around

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Speaker 1: the chemo, but also vigorous exercise just before and just

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Speaker 1: after chemo, because other research shows that that release of

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Speaker 1: adrenaline targets the chemo therapy. And doing this process, including

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Speaker 1: the fasting, every time he did CHEMEO, he went through

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Speaker 1: six rounds of pretty hard chemo and didn't have a

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Speaker 1: single day off work. Maybe even he might have had one,

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Speaker 1: but that was it. Now. Fasting, however, is not only

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Speaker 1: potential good news for cancer patients, but it's got many

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Speaker 1: other immune systems and general health benefits. So researches show

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Speaker 1: that it may reduce autoimmune conditions or the severity of

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Speaker 1: the autoimmune conditions, and according to one other study, fasting

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Speaker 1: may reduce the risk of both Parkinson's and Alzheimer's disease

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Speaker 1: partly by stimulating the really sabedianf which you've heard me

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Speaker 1: talk about ad nauseum and BDNF plays a really important

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Speaker 1: role in the creation of new brain cells and the

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Speaker 1: protection of brain cells. Now that's not the only thing.

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Speaker 1: Fasting may also reduced overall inflammation in the body, which

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Speaker 1: is a really good thing. So, according to a twenty

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Speaker 1: seventeen study, fasting for just twenty four hours can help

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Speaker 1: to deactivate what's called the NLRP three inflammazone, which is

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Speaker 1: part of your body's a near immune system that's in

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Speaker 1: charge of activating inflammatory responses. Other research papers report that

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Speaker 1: fasting can enhance mitochondrial resilience. And you've heard me go

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Speaker 1: on and on about the importance of your mitochondria as

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Speaker 1: well as preventing inflammation and have an antibi inflammatory effect

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Speaker 1: on your whole body. Now, some health professors will tell

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Speaker 1: you that fasting is risky, and that is certainly the

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Speaker 1: case if you're, say Type one diabetic or have severe

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Speaker 1: blood pressure issues. But for generally healthy people, it is

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Speaker 1: perfectly fine, and periods of fasting are very natural for

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Speaker 1: our species. You think about it, our ancestors went through many,

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Speaker 1: many periods of short term famine when food was simply

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Speaker 1: not available, and it turns out the body uses this

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Speaker 1: time for a cellular spring clean and it recycles all

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Speaker 1: parts of cells, as well as, as I said earlier,

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Speaker 1: those sinescent or zombie cells in order to produce energy.

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Speaker 1: So it's basically a system wide spring clean, pretty clever stuff,

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Speaker 1: and a fast for three or four days allows your

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Speaker 1: body to basically rest, repair and renew itself and upregularly.

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Speaker 1: It's autophogy. So what we know is as we get older,

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Speaker 1: and that autoplogy, which normally goes on very very well

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Speaker 1: in young people, it's just like many other systems. When

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Speaker 1: we're aging, it just becomes less efficient. So doing this

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Speaker 1: reasonably regularly is a good thing once you pass forty

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Speaker 1: and certainly past fifty and sixty. And by the way,

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Speaker 1: this is not medical advice. I'm just talking about what

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Speaker 1: the research says and my personal experience. It is pretty

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Speaker 1: bloody hard. In experience, I've done both a five day

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Speaker 1: fast with a fasting mimicking diet with Volter Longo, and

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Speaker 1: I've done a ten day fast. Now, what I can

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Speaker 1: tell and what others will tell you, is that you

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Speaker 1: will experience fatigue for sure, You'll experience some mental lethargy,

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Speaker 1: you will experience severe hunger, you might get some mood changes,

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Speaker 1: you might even get headaches and a bit of sleep disturbances.

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Speaker 1: And this is just a natural thing. And this happens

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Speaker 1: when we're shifting from burning glucose or sugar to burning

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Speaker 1: fat and switching into katosis. And that process of actually

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Speaker 1: switching into the katosis is a really useful thing. Now

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Speaker 1: most people and I personally found that day two was

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Speaker 1: the hardest, but by day three you'll likely have switched

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Speaker 1: full into katosis. And you can measure this using ketone strips,

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Speaker 1: and that is generally accompanied by a horizon or topogy.

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Speaker 1: You get a boost in human growth hormone, you get

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Speaker 1: a boost in your stale cells, and your blood sugar

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Speaker 1: becomes much more balance, and a lot of people report

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Speaker 1: that they get an uplift in their energy and mental

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Speaker 1: clarity because BDNF is released. Now, when you get to

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Speaker 1: this point on day three, you can decide whether you

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Speaker 1: want to do another day or two. Now, a couple

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Speaker 1: of things to note, just be aware, obviously there is

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Speaker 1: potential for muscle loss whenever you're doing that prolong fast

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Speaker 1: and the research shows you if you actually do resistance training,

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Speaker 1: probably not at your normal intensity, but just doing full

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Speaker 1: body resistance training is going to attenuate or reduce that

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Speaker 1: loss of muscle because it's going to say to the bustle, hey,

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Speaker 1: we need this. So the other thing you can use

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Speaker 1: is that fasting mimicking diet and do it for five days.

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Speaker 1: If you don't fancy going completely calorie free, you can

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Speaker 1: just look up Google fasting mimicking dat. It was created

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Speaker 1: by Walter Longo. I've got no association with whatsoever, but

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Speaker 1: it tricks the body into thinking's in a fasted state

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Speaker 1: when you're actually getting some calories. And just for those

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Speaker 1: who are concerned about doing a three or five day

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Speaker 1: water fast, the world record fast is three hundred and

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Speaker 1: eighty two days by a Scottish guy in nineteen seventy.

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Speaker 1: He went to his doc and said, Doc, I'm a

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Speaker 1: bit fat. I think I need to stop eating for

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Speaker 1: a while, and he fasted under supervision for three hundred

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Speaker 1: and eighty two days. He lost one hundred and twenty

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Speaker 1: kilos and he kept it off. So if you don't

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Speaker 1: have any serious health conditions, you can do three to five.

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Speaker 1: Catch you next time,