1 00:00:09,039 --> 00:00:13,080 Speaker 1: Hey, everybody, Welcome to another edition of Wisdom Wednesdays, and 2 00:00:13,160 --> 00:00:16,200 Speaker 1: today I want to talk about a new study that 3 00:00:16,400 --> 00:00:22,279 Speaker 1: shows how our bodies internal systems are connected in ways 4 00:00:22,320 --> 00:00:25,759 Speaker 1: that we are only just beginning to understand. So a 5 00:00:25,800 --> 00:00:29,159 Speaker 1: new study out of Australia is showing us that what 6 00:00:29,400 --> 00:00:32,960 Speaker 1: we eat doesn't just affect our wasteline or our mood. 7 00:00:33,400 --> 00:00:37,680 Speaker 1: It actually influences how our immune system operates and how 8 00:00:37,760 --> 00:00:44,120 Speaker 1: our sniper sales. Our most immune warriors are controlled, informed 9 00:00:44,280 --> 00:00:47,680 Speaker 1: and supported. So let's dive in. The study I'm talking 10 00:00:47,680 --> 00:00:50,920 Speaker 1: about comes from the team at the Dottary Institute for 11 00:00:51,040 --> 00:00:54,640 Speaker 1: Infection and Immunity at the University of Melbourne. Their work 12 00:00:54,760 --> 00:00:58,000 Speaker 1: was published in the journal Immunity, and the news piece 13 00:00:58,080 --> 00:01:03,120 Speaker 1: about it is titled Gut Control System Sniper Cells by 14 00:01:03,280 --> 00:01:07,880 Speaker 1: Remote Control. Here's what they found. They showed that diatary 15 00:01:07,959 --> 00:01:12,720 Speaker 1: fiber coming from vegetables, legomes, fermented foods, these sorts of 16 00:01:12,760 --> 00:01:18,480 Speaker 1: things plays a critical role and specifically the fiber is 17 00:01:18,600 --> 00:01:22,679 Speaker 1: used by the gut microbiome short chain fatty acids such 18 00:01:22,680 --> 00:01:25,520 Speaker 1: as beauty. It now that we've known for many, many years, 19 00:01:25,600 --> 00:01:28,680 Speaker 1: and I've talked about that before, but what they found 20 00:01:28,760 --> 00:01:32,400 Speaker 1: in this study is that those short chain fatty acids 21 00:01:32,440 --> 00:01:37,440 Speaker 1: that are produced by your gut microbiome when they digest fiber, 22 00:01:38,240 --> 00:01:45,000 Speaker 1: they then travel into the bloodstream and ultimately enhance the 23 00:01:45,120 --> 00:01:50,120 Speaker 1: precision and potency of what's called our killer taase cells. 24 00:01:50,520 --> 00:01:53,000 Speaker 1: So these you may have probably heard of them, especially 25 00:01:53,000 --> 00:01:57,360 Speaker 1: because of COVID. These are the immune sniper cells, the 26 00:01:57,560 --> 00:02:02,360 Speaker 1: killer cells that are part of our immune system, and 27 00:02:02,400 --> 00:02:07,840 Speaker 1: they play significant roles in models of cancer. Now, importantly, 28 00:02:08,240 --> 00:02:11,400 Speaker 1: the study found that it wasn't simply the presence or 29 00:02:11,560 --> 00:02:17,440 Speaker 1: absence of specific gut bacteria that determined the outcomes. Instead, 30 00:02:17,840 --> 00:02:22,200 Speaker 1: it was what those bacteria were be producing, the short 31 00:02:22,280 --> 00:02:26,880 Speaker 1: chain fatty acids that really mattered. And from a clinical perspective, 32 00:02:27,440 --> 00:02:32,080 Speaker 1: patients with higher buttorate levels, which reflects the higher fiber 33 00:02:32,160 --> 00:02:40,160 Speaker 1: intake and active gut microcrobial metabolism, they responded better to immunotherapy, 34 00:02:40,880 --> 00:02:44,920 Speaker 1: particularly for melanoma, which is a very aggressive cancer. So 35 00:02:44,960 --> 00:02:47,720 Speaker 1: the implication is pretty big for all of us that 36 00:02:47,919 --> 00:02:52,959 Speaker 1: gut is not just digesting food and passing nutrients, it's 37 00:02:53,080 --> 00:02:59,160 Speaker 1: actually sending metabolic messages far beyond itself to our immune system. 38 00:02:59,560 --> 00:03:03,240 Speaker 1: And I've told about how eighty percent of your immune 39 00:03:03,280 --> 00:03:08,320 Speaker 1: system resides at the gut barrier, and it turns out 40 00:03:08,360 --> 00:03:11,120 Speaker 1: that this is really really critical in ways that we 41 00:03:11,240 --> 00:03:15,120 Speaker 1: didn't understand. That those messages that are coming from the 42 00:03:15,160 --> 00:03:19,519 Speaker 1: gut to the immune system influence how well our rest 43 00:03:19,560 --> 00:03:25,639 Speaker 1: body respawn to major threats like cancer and likely many 44 00:03:25,760 --> 00:03:28,799 Speaker 1: other immune challenges. Right, so, just because this was done 45 00:03:28,800 --> 00:03:32,000 Speaker 1: on cancer doesn't mean it's just limited to this. It 46 00:03:32,080 --> 00:03:36,240 Speaker 1: is actually training the natural natural killer sales of your 47 00:03:36,280 --> 00:03:39,960 Speaker 1: immune system, which are hugely important in combating all sorts 48 00:03:39,960 --> 00:03:43,800 Speaker 1: of So why I should be kurt, Well, there's really 49 00:03:43,840 --> 00:03:47,920 Speaker 1: three big reasons. The first is that you can really 50 00:03:48,080 --> 00:03:52,880 Speaker 1: influence your immune system through your diet. This research gives 51 00:03:52,960 --> 00:03:57,040 Speaker 1: us something really actionable. It reinforces the idea that what 52 00:03:57,200 --> 00:04:03,280 Speaker 1: we eat, especially five, doesn't just keep us healthy in 53 00:04:03,320 --> 00:04:07,840 Speaker 1: a generic sense. It actively supports our immune system's elite 54 00:04:07,920 --> 00:04:12,119 Speaker 1: killer cells. And we're seeing the mechanism as such that 55 00:04:12,240 --> 00:04:17,800 Speaker 1: the fiber that you eat feeds certain microbes that then 56 00:04:17,880 --> 00:04:22,640 Speaker 1: produce these short chain fatty acids that results in stronger, 57 00:04:22,960 --> 00:04:27,320 Speaker 1: more precise T cells immr immune system. And this really 58 00:04:27,400 --> 00:04:31,960 Speaker 1: makes us rethink the gut immune connection. Many people think 59 00:04:32,080 --> 00:04:36,159 Speaker 1: gut health means digestion, bloating, and maybe influences their mood. 60 00:04:36,520 --> 00:04:40,080 Speaker 1: But this shows that the guts rates extends into classic 61 00:04:41,680 --> 00:04:45,560 Speaker 1: the kind we associated with batting infection or cancer. And 62 00:04:45,600 --> 00:04:48,960 Speaker 1: then the third one is really about prevention and resilience, 63 00:04:49,520 --> 00:04:53,360 Speaker 1: even if you're not facing cancer or serious disease right now. 64 00:04:54,000 --> 00:04:58,720 Speaker 1: This research suggests that building a gut environment that supports 65 00:04:58,760 --> 00:05:04,240 Speaker 1: these beneficial pathways actually booster your long term health resilience. 66 00:05:04,880 --> 00:05:06,520 Speaker 1: And one way to think of it is that the 67 00:05:06,600 --> 00:05:11,680 Speaker 1: body has got better sniper cells ready or ready they 68 00:05:11,680 --> 00:05:15,360 Speaker 1: are waiting for something to come in so that it 69 00:05:15,440 --> 00:05:20,000 Speaker 1: can actually act. So the take on message is clear. 70 00:05:20,920 --> 00:05:25,280 Speaker 1: One is to prioritize fiber rich foods, making sure you've 71 00:05:25,279 --> 00:05:29,040 Speaker 1: got plenty of vegetables, leg goomes and fermented foods, and 72 00:05:29,560 --> 00:05:32,880 Speaker 1: real whole grains, not breakfast cereals, but real whole grains, 73 00:05:33,120 --> 00:05:37,320 Speaker 1: because these are the substrates that the gut microbes use 74 00:05:37,440 --> 00:05:41,279 Speaker 1: to produce these beneficial short chain fary acids like and 75 00:05:41,360 --> 00:05:44,280 Speaker 1: I've talked about before about beatay it and other short 76 00:05:44,320 --> 00:05:47,400 Speaker 1: chain fairy acids are good for your gut lining, they're 77 00:05:47,400 --> 00:05:50,159 Speaker 1: good for your heart, they're good for your brain. We 78 00:05:50,360 --> 00:05:53,560 Speaker 1: now know they're good for your immune system, and we 79 00:05:53,680 --> 00:05:56,440 Speaker 1: really need to think of our gut microbiome as an 80 00:05:56,480 --> 00:06:02,480 Speaker 1: important ally in our health, moving the bad bugs or 81 00:06:02,520 --> 00:06:07,400 Speaker 1: taking probiotics. It's actually about supporting your overall gut function. 82 00:06:07,520 --> 00:06:11,680 Speaker 1: And we know that diversity is really important. But we 83 00:06:11,720 --> 00:06:15,800 Speaker 1: also know that regular physical activity actually changes your microbiome 84 00:06:15,839 --> 00:06:19,080 Speaker 1: in positive ways, as does good sleep, and if you've 85 00:06:19,120 --> 00:06:25,840 Speaker 1: got shithouse physically active, your microbiome actually degrades. And what 86 00:06:25,880 --> 00:06:30,080 Speaker 1: we're seeing really with this research is that we often 87 00:06:30,320 --> 00:06:33,760 Speaker 1: activate our immune system when something happens, like whether it's 88 00:06:33,760 --> 00:06:37,839 Speaker 1: illness or infection. But these stress research is telling us 89 00:06:38,200 --> 00:06:42,360 Speaker 1: that the preparation the ground works well ahead of time. 90 00:06:42,440 --> 00:06:46,200 Speaker 1: It's just like the army of an issue being trained 91 00:06:46,320 --> 00:06:50,920 Speaker 1: well so that it can respond whenever stuff happens. These 92 00:06:50,920 --> 00:06:55,400 Speaker 1: sniper cells don't just appear overnight, They actually evolve over time. 93 00:06:56,200 --> 00:06:59,920 Speaker 1: So this is just another reason if we needed another one. 94 00:07:01,000 --> 00:07:04,640 Speaker 1: You're eating a healthy diet with a large range of 95 00:07:04,640 --> 00:07:09,440 Speaker 1: foods and making sure that you're having reasonable fiber intake 96 00:07:09,840 --> 00:07:13,080 Speaker 1: because your immune system will love you for it, particularly 97 00:07:13,120 --> 00:07:16,240 Speaker 1: when you need your immune system the most. That's it 98 00:07:16,280 --> 00:07:18,480 Speaker 1: for this week, folks, Catch you next time.