1 00:00:09,280 --> 00:00:12,880 Speaker 1: Hey, everybody, welcome to another edition of Wisdom Wednesdays. So 2 00:00:13,000 --> 00:00:16,800 Speaker 1: today we are going to talk about protein intake because 3 00:00:16,840 --> 00:00:20,319 Speaker 1: I've just done a series on anti aging and I've 4 00:00:20,400 --> 00:00:25,040 Speaker 1: mentioned before that I think that the recommended guidelines, particularly 5 00:00:25,040 --> 00:00:29,320 Speaker 1: for older adults, are suboptimal, and there was a study 6 00:00:29,440 --> 00:00:32,760 Speaker 1: that was recently published that set out to determine just that, 7 00:00:33,640 --> 00:00:36,520 Speaker 1: and so let's dive into the details of the study. 8 00:00:36,560 --> 00:00:40,519 Speaker 1: It was a twelve week randomized control trial in older 9 00:00:40,560 --> 00:00:44,239 Speaker 1: adults and their average age was around sixty years old. Now, 10 00:00:44,240 --> 00:00:48,400 Speaker 1: they all had type two diabetes and signs of sarcopamia, 11 00:00:48,720 --> 00:00:52,280 Speaker 1: which is that loss of muscle mass and strength and 12 00:00:52,360 --> 00:00:55,800 Speaker 1: bone that is associated with aging, and what they find 13 00:00:56,920 --> 00:01:01,800 Speaker 1: was really significant. Twenty six participate were split into two groups. 14 00:01:02,320 --> 00:01:06,520 Speaker 1: One group consumed a higher protein diet, which was about 15 00:01:06,560 --> 00:01:10,160 Speaker 1: one point two to one point five grams of protein 16 00:01:10,240 --> 00:01:13,520 Speaker 1: per kilogram of body weight per day a've reached over 17 00:01:13,600 --> 00:01:17,600 Speaker 1: the period, and the other group had a lower protein 18 00:01:17,680 --> 00:01:21,720 Speaker 1: diet around not pointing it to one grams per kilogram 19 00:01:22,640 --> 00:01:25,520 Speaker 1: and that not point eight, you might remember, is the 20 00:01:25,600 --> 00:01:30,360 Speaker 1: Recommended Daily Alliance or RDA. So they were consuming the 21 00:01:30,480 --> 00:01:35,399 Speaker 1: RDA or slightly more and after twelve reeks. The results 22 00:01:35,840 --> 00:01:40,240 Speaker 1: were pretty down clear appendicular lean mass, so that's the 23 00:01:40,280 --> 00:01:44,360 Speaker 1: amount of lean mass in your arms and legs dropped 24 00:01:44,760 --> 00:01:48,240 Speaker 1: by almost two kilos. It was just over one and 25 00:01:48,240 --> 00:01:51,600 Speaker 1: a half kilos actually in the lower protein group. But 26 00:01:51,760 --> 00:01:56,280 Speaker 1: in contrasted increase by a kilo in the high protein group, 27 00:01:56,800 --> 00:02:01,960 Speaker 1: So that's a two kilo swing or almost five pounds, 28 00:02:02,280 --> 00:02:07,040 Speaker 1: which is really really significant in twelve weeks. And on 29 00:02:07,160 --> 00:02:11,079 Speaker 1: top of that, physical function was better in the high 30 00:02:11,160 --> 00:02:16,160 Speaker 1: protein group. They had improvements in handgrip strength, in gate speed, 31 00:02:16,560 --> 00:02:20,560 Speaker 1: and balanced test performance, and these are all very important 32 00:02:20,600 --> 00:02:25,520 Speaker 1: tests as you age. Interestingly, though, there weren't any differences 33 00:02:25,639 --> 00:02:28,200 Speaker 1: in a sit to stand or a timed up and 34 00:02:28,280 --> 00:02:31,480 Speaker 1: go test between the two groups, and it may just 35 00:02:31,480 --> 00:02:33,960 Speaker 1: have been that it was a little bit short for that. 36 00:02:34,480 --> 00:02:38,799 Speaker 1: But here's the kicker. Our muscle tissue is constantly being 37 00:02:38,840 --> 00:02:41,519 Speaker 1: broken down and built back up because we don't have 38 00:02:42,240 --> 00:02:46,120 Speaker 1: a big storage capacity for amino acids, and we need 39 00:02:46,160 --> 00:02:49,960 Speaker 1: a constant supply of amino acids. Your organs all need 40 00:02:50,120 --> 00:02:53,440 Speaker 1: amino acids. They are the building blocks of life. And 41 00:02:53,480 --> 00:02:58,120 Speaker 1: the key player in building muscle and maintaining your muscle 42 00:02:58,440 --> 00:03:02,760 Speaker 1: is something called muscle protein synthesis. So for muscle mass 43 00:03:02,800 --> 00:03:07,000 Speaker 1: to increase, muscle protein synthesis needs to exceed the rate 44 00:03:07,080 --> 00:03:11,480 Speaker 1: of muscle protein breakdown. And as we age, this process 45 00:03:11,520 --> 00:03:15,120 Speaker 1: becomes less efficient, and that's a phenomenon that is known 46 00:03:15,240 --> 00:03:20,240 Speaker 1: as anabolic resistance. So we actually become slightly resistant to 47 00:03:20,360 --> 00:03:24,040 Speaker 1: building muscle as we age. And what this means is 48 00:03:24,360 --> 00:03:28,640 Speaker 1: when an older adult eats protein, their body doesn't ramp 49 00:03:28,720 --> 00:03:32,480 Speaker 1: up muscle protein synthesis as much as a younger person's 50 00:03:32,520 --> 00:03:36,440 Speaker 1: body would. In fact, older adults may need nearly twice 51 00:03:36,480 --> 00:03:40,000 Speaker 1: as much protein per meal to get the same response, 52 00:03:40,600 --> 00:03:45,040 Speaker 1: and yet we have these very low recommended guidelines. And 53 00:03:45,240 --> 00:03:48,080 Speaker 1: what we also know from studies is that as people 54 00:03:48,080 --> 00:03:50,200 Speaker 1: get older, they tend to eat less and eat less 55 00:03:50,200 --> 00:03:54,160 Speaker 1: protein and to put numbers on it, and young adults 56 00:03:54,200 --> 00:03:58,320 Speaker 1: can achieve maximum protein synthesis according to studies with a 57 00:03:58,360 --> 00:04:03,480 Speaker 1: male containing around not zero point two five grams of 58 00:04:03,520 --> 00:04:06,080 Speaker 1: protein per kilogram of body weight, so about a quarter 59 00:04:06,240 --> 00:04:08,560 Speaker 1: of a gram of protein per kilogram of body weight, 60 00:04:09,000 --> 00:04:13,560 Speaker 1: But older adults need more like zero point four grams 61 00:04:13,640 --> 00:04:16,880 Speaker 1: of protein per kilogram of body weight. That's per meal, 62 00:04:17,279 --> 00:04:20,080 Speaker 1: and that's a big, big difference and that brings us 63 00:04:20,080 --> 00:04:23,480 Speaker 1: back to this study. So the lower protein group, the 64 00:04:23,520 --> 00:04:27,479 Speaker 1: one that lost muscle, was consuming the RDA as I 65 00:04:27,480 --> 00:04:32,120 Speaker 1: said earlier, which is that it's actually the RDA is 66 00:04:32,160 --> 00:04:35,200 Speaker 1: the minimum needed to prevent deficiencies. That's what it was 67 00:04:35,320 --> 00:04:39,640 Speaker 1: established as. It's not designed to be optimal, but people 68 00:04:39,680 --> 00:04:43,880 Speaker 1: think it's a recommendation. What is clear is it's not 69 00:04:44,040 --> 00:04:47,520 Speaker 1: the minimum needed to prevent deficiencies in older adults. It 70 00:04:47,600 --> 00:04:50,560 Speaker 1: may be in younger adults, but not older so it's 71 00:04:50,600 --> 00:04:54,039 Speaker 1: not surprising that muscle mass and grip strength declined in 72 00:04:54,120 --> 00:04:56,440 Speaker 1: that group, and it's not a one off result. There's 73 00:04:56,480 --> 00:05:00,080 Speaker 1: another randomized trial in older adults showed that consumers I 74 00:05:00,080 --> 00:05:02,520 Speaker 1: mean one point five grams per kilogram of protein per 75 00:05:02,600 --> 00:05:07,800 Speaker 1: day resultant in significantly higher muscle protein synthesis over a 76 00:05:07,880 --> 00:05:12,599 Speaker 1: twenty two hour period compared to consuming the RDA of 77 00:05:12,760 --> 00:05:16,800 Speaker 1: zero point eight grams per kilogram, and long term observational 78 00:05:16,800 --> 00:05:20,000 Speaker 1: studies show the same thing. People sticking to just the 79 00:05:20,120 --> 00:05:24,520 Speaker 1: RDA tend to lose muscle over time, and you do 80 00:05:24,560 --> 00:05:28,600 Speaker 1: not want to lose muscle as you age. And in fact, 81 00:05:28,600 --> 00:05:32,440 Speaker 1: going back to the data here, a metaaly meta analysis 82 00:05:32,960 --> 00:05:37,560 Speaker 1: published in twenty twenty concluded that protein integrates averaging one 83 00:05:37,600 --> 00:05:41,600 Speaker 1: point three grams per kilogram today led to greater muscle 84 00:05:41,680 --> 00:05:44,480 Speaker 1: mass gains than sticking with the RDA. So the evidence 85 00:05:44,600 --> 00:05:49,480 Speaker 1: is becoming really clear and we need to change these recommendations, 86 00:05:49,560 --> 00:05:54,440 Speaker 1: particularly for older adults. So how much is ideal based 87 00:05:54,440 --> 00:05:58,760 Speaker 1: on this and other research? I would say at least 88 00:05:59,440 --> 00:06:02,600 Speaker 1: one point two grams per kilogram per day, but really 89 00:06:02,720 --> 00:06:05,760 Speaker 1: you should be looking at I think one point six 90 00:06:05,839 --> 00:06:08,600 Speaker 1: grams per kilogram per day up to two grams per 91 00:06:08,680 --> 00:06:11,680 Speaker 1: kilogram today, and that's not just my opinion, that's looking 92 00:06:11,680 --> 00:06:15,360 Speaker 1: at lots of different studies that might be optimal one 93 00:06:15,400 --> 00:06:18,360 Speaker 1: point six grams per kilogram of body weight to two 94 00:06:18,400 --> 00:06:21,400 Speaker 1: grams of kilogram of bodyweight per day if you're an 95 00:06:21,400 --> 00:06:25,160 Speaker 1: older adult who wants to maintain their muscle mass. And 96 00:06:25,200 --> 00:06:29,000 Speaker 1: then obviously adding in strength training is really really key. 97 00:06:29,560 --> 00:06:32,360 Speaker 1: And one study of people aid is fifty to seventy 98 00:06:32,800 --> 00:06:36,440 Speaker 1: those who consumed one point six grams per kilogram of 99 00:06:36,480 --> 00:06:40,640 Speaker 1: bodyweight per day of protein over twenty four weeks gained 100 00:06:40,680 --> 00:06:44,200 Speaker 1: more muscle than those consuming one point two grams per kilogram. 101 00:06:44,279 --> 00:06:48,400 Speaker 1: So that really tends to suggest that one point six 102 00:06:48,680 --> 00:06:51,760 Speaker 1: should be your bottom number here and why we don't 103 00:06:51,800 --> 00:06:55,800 Speaker 1: have enough long term studies and older adults at higher intakes. 104 00:06:56,480 --> 00:07:01,080 Speaker 1: The younger adult studies show a clear dose response. More protein, 105 00:07:01,760 --> 00:07:04,800 Speaker 1: even up to three and a half grams per kilogram 106 00:07:04,839 --> 00:07:08,400 Speaker 1: per day equates to more muscle mass. So the takeaway 107 00:07:08,440 --> 00:07:11,840 Speaker 1: here is very clear if you're an older adult, and 108 00:07:11,880 --> 00:07:14,440 Speaker 1: we know that anabolic resistance can start to kick in 109 00:07:15,040 --> 00:07:17,080 Speaker 1: at the age of forty or fifty for people, so 110 00:07:17,280 --> 00:07:19,640 Speaker 1: if you're over the age of forty, I think to 111 00:07:19,680 --> 00:07:23,000 Speaker 1: be see if your protein intakes should be a minimum 112 00:07:23,000 --> 00:07:26,640 Speaker 1: of one point six grams per kilogram per day and 113 00:07:27,280 --> 00:07:30,600 Speaker 1: up to two or it may be even more, particularly 114 00:07:30,600 --> 00:07:33,880 Speaker 1: if you're doing resistance training and you want to avoid 115 00:07:34,000 --> 00:07:37,640 Speaker 1: scyclopedia which I think we should be avoiding like the plague. 116 00:07:38,080 --> 00:07:40,080 Speaker 1: That's it for this week, folks, catch you next time.