1 00:00:09,119 --> 00:00:12,000 Speaker 1: Doctor Joshua Piet, Welcome to the podcast. 2 00:00:12,360 --> 00:00:13,840 Speaker 2: Thanks for having me. Paul. 3 00:00:14,120 --> 00:00:17,200 Speaker 1: Yes, now, as we just discussed, if you grew up 4 00:00:17,239 --> 00:00:20,799 Speaker 1: in Belfast, you would just be called pat yet. 5 00:00:21,440 --> 00:00:25,200 Speaker 2: Yeah, no, that's fine. It's reminiscent of my high school years. 6 00:00:26,440 --> 00:00:29,520 Speaker 1: So pat and that would just be it, you'd be Patie. 7 00:00:30,280 --> 00:00:34,200 Speaker 1: But clearly doctor Joshua Pitt, Now you are a physiotherapist 8 00:00:34,200 --> 00:00:39,879 Speaker 1: with a special interest in pain and Pean education. So 9 00:00:40,560 --> 00:00:42,400 Speaker 1: how did you get into what was your what's your PhD? 10 00:00:42,560 --> 00:00:46,600 Speaker 2: In as in how kids think about pain and kind 11 00:00:46,600 --> 00:00:49,560 Speaker 2: of trying to get the simplest language we can about 12 00:00:49,600 --> 00:00:52,840 Speaker 2: this stuff because I like, clinically we saw patients getting 13 00:00:52,880 --> 00:00:56,880 Speaker 2: better with learning about the neuroscience and it was kind 14 00:00:56,880 --> 00:00:58,960 Speaker 2: of like, oh, surely people don't have to become a 15 00:00:59,000 --> 00:01:03,440 Speaker 2: neuroscientist get better, and like, just engaging with these active 16 00:01:03,480 --> 00:01:06,640 Speaker 2: strategies for a long time, having a bit of a 17 00:01:06,680 --> 00:01:09,800 Speaker 2: scientific foundation seem to help people. And so then the 18 00:01:09,840 --> 00:01:11,880 Speaker 2: goal with my PhD was like, how can we work 19 00:01:11,920 --> 00:01:14,040 Speaker 2: out how to simplify that as much as we can? 20 00:01:14,800 --> 00:01:17,240 Speaker 2: And I worked in the children's hospital and so we 21 00:01:17,319 --> 00:01:20,440 Speaker 2: kind of joined all those different dots together. But yeah, 22 00:01:20,480 --> 00:01:23,039 Speaker 2: more or less. I guess we even took a step 23 00:01:23,080 --> 00:01:24,880 Speaker 2: back from going, well, what should we say to the 24 00:01:24,959 --> 00:01:27,480 Speaker 2: kids and started thinking about how do we assess and 25 00:01:27,520 --> 00:01:31,039 Speaker 2: where's the starting point and so doing things like we've 26 00:01:31,080 --> 00:01:33,320 Speaker 2: got kids to draw whatever they think of when they 27 00:01:33,440 --> 00:01:36,280 Speaker 2: hear the word pain. Actually, what would you draw if 28 00:01:36,280 --> 00:01:38,320 Speaker 2: you had to do that task? Can to hear? 29 00:01:38,360 --> 00:01:43,080 Speaker 1: Its interesting? What would I draw? I would probably draw 30 00:01:44,480 --> 00:01:50,480 Speaker 1: something throbbing, rare, inflammation, all that stuff as probably what 31 00:01:50,520 --> 00:01:52,240 Speaker 1: I would draw. Yeah, I do this. 32 00:01:52,160 --> 00:01:55,160 Speaker 2: With my university, like the Masters of physio students, and 33 00:01:55,200 --> 00:01:58,440 Speaker 2: they often draw things like abstract things like a squiggly 34 00:01:58,560 --> 00:02:02,320 Speaker 2: line or like a mess or fire or whereas kids 35 00:02:02,400 --> 00:02:05,240 Speaker 2: under the age of twelve they're not thinking abstractly at all, 36 00:02:05,240 --> 00:02:07,560 Speaker 2: Like the brain hasn't developed that yet, and so it's 37 00:02:07,560 --> 00:02:10,240 Speaker 2: all very concrete. It's just like a broken bone, a 38 00:02:10,320 --> 00:02:12,560 Speaker 2: sad And if they've had chronic pain, they often draw 39 00:02:12,600 --> 00:02:16,720 Speaker 2: like emotional things like sad faces, right, broken hearts, that 40 00:02:16,840 --> 00:02:19,120 Speaker 2: kind of stuff, whereas if they haven't had chronic pain, 41 00:02:19,400 --> 00:02:21,839 Speaker 2: normally it's just an injury. And I guess if we're 42 00:02:21,880 --> 00:02:24,799 Speaker 2: growing up in a culture where pain is just associated 43 00:02:24,840 --> 00:02:28,800 Speaker 2: with injuries, it's quite hard to be empathetic if it's invisible, 44 00:02:28,880 --> 00:02:30,600 Speaker 2: right like, And so a lot of my research has 45 00:02:30,680 --> 00:02:32,320 Speaker 2: kind of been in that space, is like, can we 46 00:02:32,400 --> 00:02:35,400 Speaker 2: nip things in the bud and help people really early 47 00:02:35,440 --> 00:02:40,320 Speaker 2: on in society, like at a generational level, because potentially 48 00:02:40,320 --> 00:02:42,680 Speaker 2: that could stop some of at least the stigma but 49 00:02:42,720 --> 00:02:46,080 Speaker 2: potentially even some of the disability associated that happens with 50 00:02:46,160 --> 00:02:49,680 Speaker 2: pain because people go, well, it's if I'm damaged, then 51 00:02:49,680 --> 00:02:52,480 Speaker 2: I better rest and if I rest more then maybe 52 00:02:52,480 --> 00:02:55,079 Speaker 2: I'll get even better. And so then they stop engaging 53 00:02:55,080 --> 00:03:00,000 Speaker 2: in meaningful activities and that actually worsens pain. Bit yeah, 54 00:03:00,639 --> 00:03:03,160 Speaker 2: this complex web, right, yeah. 55 00:03:02,880 --> 00:03:09,400 Speaker 1: Yeah, absolutely, Now this complex web clearly involves the nervous 56 00:03:09,440 --> 00:03:14,560 Speaker 1: system and the brain. I saw a guy and a 57 00:03:14,680 --> 00:03:19,359 Speaker 1: really a neuroscientist on TED must be ten fifteen years ago, 58 00:03:19,880 --> 00:03:25,960 Speaker 1: Ramachandrin or something like that, talking about phantom limpain and 59 00:03:26,040 --> 00:03:28,640 Speaker 1: the use of mirror boxes. I think that's a really 60 00:03:28,680 --> 00:03:33,640 Speaker 1: good starting point and to dive into the whole science 61 00:03:33,680 --> 00:03:38,080 Speaker 1: of pain. Give it, give our listeners a view of 62 00:03:38,600 --> 00:03:41,720 Speaker 1: because you've done a great ted X video on phantom 63 00:03:41,760 --> 00:03:45,320 Speaker 1: limpiin so give us you know what is phantom limpain? 64 00:03:45,720 --> 00:03:48,680 Speaker 1: What do we know about it and heart of mirror 65 00:03:48,720 --> 00:03:50,600 Speaker 1: boxes actually help people. 66 00:03:51,120 --> 00:03:53,520 Speaker 2: Yeah, I think there's still a fair bit of mystery 67 00:03:53,720 --> 00:03:59,120 Speaker 2: around the full understanding, but I guess one way that 68 00:03:59,120 --> 00:04:01,960 Speaker 2: this has been explained is to think about your brain 69 00:04:02,000 --> 00:04:06,560 Speaker 2: having a map. It's called yourmunculus, and the map kind 70 00:04:06,600 --> 00:04:11,680 Speaker 2: of correlates with different parts of your body, and so yeah, 71 00:04:11,720 --> 00:04:14,080 Speaker 2: basically if part of the map is lighting up, then 72 00:04:14,080 --> 00:04:16,040 Speaker 2: you would feel pain, Like I guess if we kind 73 00:04:16,080 --> 00:04:18,080 Speaker 2: of have a little simple model like that, and so 74 00:04:18,120 --> 00:04:21,040 Speaker 2: then if someone has an amputation, they might feel pain 75 00:04:21,200 --> 00:04:23,080 Speaker 2: in the hand that's missing. Like I can think of 76 00:04:23,120 --> 00:04:25,560 Speaker 2: patients who have said, oh, it's like my hands still 77 00:04:25,560 --> 00:04:28,880 Speaker 2: on the Harley Davidson handlebars, but I don't have an arm, 78 00:04:29,120 --> 00:04:31,080 Speaker 2: and they can say, like I can tell my pinky 79 00:04:31,200 --> 00:04:34,120 Speaker 2: is all curled up, but there's no arm there, and 80 00:04:34,160 --> 00:04:36,480 Speaker 2: it's like, well, how does that, like, how can that 81 00:04:36,720 --> 00:04:40,400 Speaker 2: happen if there is no arm? And so yeah, remtrendry. 82 00:04:40,400 --> 00:04:42,440 Speaker 2: There's a bunch of different researchers from a long time ago, 83 00:04:42,480 --> 00:04:44,960 Speaker 2: and the idea was, well, maybe it's a top down 84 00:04:45,200 --> 00:04:49,560 Speaker 2: kind of brain down perspective on what's going on in 85 00:04:49,600 --> 00:04:52,080 Speaker 2: the body. And there's lots of research even around like 86 00:04:52,160 --> 00:04:55,080 Speaker 2: pery personal space, like the space around your body. Kind 87 00:04:55,120 --> 00:04:58,359 Speaker 2: of similar mechanisms at play here, where the brain is 88 00:04:58,400 --> 00:05:01,239 Speaker 2: predicting what's happening in the spinal the spinal cords predicting 89 00:05:01,240 --> 00:05:04,040 Speaker 2: what's happening around in the peripheral nervous system, and then 90 00:05:04,040 --> 00:05:06,960 Speaker 2: that's predicting what's happening in the space around you. And 91 00:05:07,000 --> 00:05:09,320 Speaker 2: so for fantom win pain where there's no limb there, 92 00:05:09,640 --> 00:05:12,080 Speaker 2: it makes better sense than that the body's trying to 93 00:05:12,120 --> 00:05:16,240 Speaker 2: protect that part that was really threatened. And because it 94 00:05:16,320 --> 00:05:19,839 Speaker 2: was such a big experience having something amputated or the 95 00:05:19,880 --> 00:05:23,880 Speaker 2: accident or whatever preceded it, that pain can persist and 96 00:05:23,920 --> 00:05:26,560 Speaker 2: it often does persist. And then that also helps explain 97 00:05:26,560 --> 00:05:28,600 Speaker 2: when someone puts on a prosthetic at night, or they 98 00:05:28,600 --> 00:05:30,480 Speaker 2: take off their prosthetic and it hurts, or they put 99 00:05:30,520 --> 00:05:32,560 Speaker 2: their prosthetic on in it and it gives pain relief. 100 00:05:33,680 --> 00:05:38,560 Speaker 1: So yeah, interesting, So they take the prosthetic off and 101 00:05:38,600 --> 00:05:40,720 Speaker 1: they actually feel pain and then they put it. 102 00:05:40,920 --> 00:05:46,279 Speaker 2: Yeah, because there's no embodiment of that. But it is tricky, 103 00:05:46,320 --> 00:05:48,599 Speaker 2: and there's some people who would argue, oh, no, it's 104 00:05:48,640 --> 00:05:51,320 Speaker 2: the nerve endings that have been cut, and that's sending 105 00:05:51,520 --> 00:05:54,120 Speaker 2: a peripheral message going up to the brain. And I 106 00:05:54,160 --> 00:05:56,800 Speaker 2: think where I sit now, like years and years on 107 00:05:57,000 --> 00:05:59,080 Speaker 2: from this is there. It's somewhere in the middle. And 108 00:05:59,120 --> 00:06:02,800 Speaker 2: I think it's both pain is a whole person experience, 109 00:06:02,880 --> 00:06:07,120 Speaker 2: Like it's not brain centric and it's not body part centric. 110 00:06:07,200 --> 00:06:10,560 Speaker 2: I think it's very hard to separate any Like, I 111 00:06:10,600 --> 00:06:13,400 Speaker 2: think that separation of brain and body is really kind 112 00:06:13,400 --> 00:06:15,200 Speaker 2: of unhelpful in some ways. 113 00:06:15,320 --> 00:06:18,719 Speaker 1: A bit. It's so unhelpful in so many bloody ways. 114 00:06:18,839 --> 00:06:22,560 Speaker 2: Yeah, And if you join them together, then the latest 115 00:06:22,600 --> 00:06:26,559 Speaker 2: research on the immune system and other parts of your 116 00:06:26,720 --> 00:06:29,920 Speaker 2: body that we kind of separate as parts or different systems, 117 00:06:30,360 --> 00:06:32,920 Speaker 2: you start seeing them all as overlaying on each other 118 00:06:33,160 --> 00:06:36,000 Speaker 2: rather than as separate things. And I think that's much 119 00:06:36,040 --> 00:06:38,760 Speaker 2: more helpful because then when someone comes to the clinic 120 00:06:38,839 --> 00:06:41,600 Speaker 2: and they've got bad sleep and they're getting sick all 121 00:06:41,640 --> 00:06:43,640 Speaker 2: the time, and their memory is going and all these 122 00:06:43,640 --> 00:06:47,119 Speaker 2: other factors, it's all one big picture, like it makes 123 00:06:47,160 --> 00:06:52,320 Speaker 2: perfect sense, rather than it being this confusing, anger inducing experience. 124 00:06:53,400 --> 00:06:55,039 Speaker 2: So I've kind of derailed a little bit from the 125 00:06:55,040 --> 00:06:58,200 Speaker 2: phantom blim question, But I think the key point there, 126 00:06:58,200 --> 00:07:03,200 Speaker 2: I guess, is thinking about a whole person's being under threat. Like, 127 00:07:03,200 --> 00:07:06,880 Speaker 2: so pain is about warning and threat and safety rather 128 00:07:06,920 --> 00:07:11,080 Speaker 2: than necessarily just about damage and blacking. 129 00:07:11,240 --> 00:07:15,480 Speaker 1: Yeah, yeah, yeah, and that makes sense, particularly for people 130 00:07:15,960 --> 00:07:19,200 Speaker 1: with chronic pin right. And I just want to come 131 00:07:19,240 --> 00:07:25,000 Speaker 1: back to the homunculous Penfold maps. Does that play because 132 00:07:25,040 --> 00:07:28,560 Speaker 1: I remember there was a neural surgeon I'm pretty sure 133 00:07:28,640 --> 00:07:31,240 Speaker 1: Penfold and what he would do when he was operating 134 00:07:31,680 --> 00:07:36,160 Speaker 1: on patients when they were conscious, he would touch different 135 00:07:36,240 --> 00:07:38,920 Speaker 1: parts of the brain and that with a little probe 136 00:07:38,920 --> 00:07:41,200 Speaker 1: and they would go, oh, I feel latten my foot. Oh, 137 00:07:41,240 --> 00:07:44,320 Speaker 1: I feel lattened my finger. Ooh, I feel like somewhere else. 138 00:07:44,960 --> 00:07:48,440 Speaker 1: And he started creating these maps, these Penfold maps. Is 139 00:07:48,880 --> 00:07:52,280 Speaker 1: that Does that play into the homoculous presumably it does. 140 00:07:52,560 --> 00:07:55,640 Speaker 2: Yeah, like all of these again, it's just so hard 141 00:07:55,640 --> 00:07:58,080 Speaker 2: to separate out one, Like, so you look at all 142 00:07:58,120 --> 00:08:00,320 Speaker 2: these studies in isolation, and then you try to add 143 00:08:00,320 --> 00:08:03,080 Speaker 2: them all together, and yeah, I think for sure there's 144 00:08:03,200 --> 00:08:06,480 Speaker 2: there's almost like the latest understanding would be there's a 145 00:08:06,520 --> 00:08:09,200 Speaker 2: map for the motor system and then there's a sensory 146 00:08:09,280 --> 00:08:12,720 Speaker 2: map and so and they're not necessarily identical or the same, 147 00:08:12,760 --> 00:08:15,520 Speaker 2: and they're in slightly different parts of the brain. But yeah, 148 00:08:15,560 --> 00:08:20,680 Speaker 2: this idea that like our world is being represented in 149 00:08:20,680 --> 00:08:24,120 Speaker 2: our brain somehow is a really complex thing to even 150 00:08:24,160 --> 00:08:27,320 Speaker 2: start grappling with. And I noticed when I said that 151 00:08:27,360 --> 00:08:29,680 Speaker 2: before you said, oh, that definitely applies to chronic pain 152 00:08:29,720 --> 00:08:32,440 Speaker 2: and that, and I think it people can latch onto 153 00:08:32,440 --> 00:08:35,560 Speaker 2: that idea pretty comfortably. But what I'm seeing more and 154 00:08:35,600 --> 00:08:38,640 Speaker 2: more is like, why wouldn't it apply to acute pain 155 00:08:38,679 --> 00:08:42,400 Speaker 2: and injury? And in those moments like if you, I 156 00:08:42,400 --> 00:08:44,800 Speaker 2: don't know, bend your finger back and it starts hurting, 157 00:08:45,880 --> 00:08:48,920 Speaker 2: you haven't caused any damage yet, the warning's kicking in 158 00:08:49,200 --> 00:08:51,680 Speaker 2: and then you let go and there's no damage and 159 00:08:51,720 --> 00:08:55,960 Speaker 2: the pain settles down and it's kind of in proportion relatively. 160 00:08:56,520 --> 00:08:58,880 Speaker 2: But it's when the pain isn't in the same proportion 161 00:08:59,000 --> 00:09:02,040 Speaker 2: as the damage that it gets really really hard to understand. 162 00:09:02,120 --> 00:09:04,280 Speaker 2: And this is what, like, I mean, twenty percent of 163 00:09:04,320 --> 00:09:06,640 Speaker 2: society have chronic pain in some way, and a lot 164 00:09:06,679 --> 00:09:10,319 Speaker 2: of that is dismissed because our society set up, oh, 165 00:09:10,400 --> 00:09:12,679 Speaker 2: let's go and get a scan and see the structure 166 00:09:12,720 --> 00:09:15,440 Speaker 2: that's wrong with you. And I guess that just that 167 00:09:15,480 --> 00:09:17,840 Speaker 2: whole starting point is just it doesn't make a whole 168 00:09:17,840 --> 00:09:20,559 Speaker 2: lot of sense based on the later science. I think 169 00:09:20,559 --> 00:09:23,000 Speaker 2: we need to be thinking more about the whole person 170 00:09:23,520 --> 00:09:26,800 Speaker 2: and threat rather than about a disk or a little 171 00:09:26,840 --> 00:09:30,560 Speaker 2: body part. Of course, like we need to advocate for 172 00:09:30,600 --> 00:09:32,520 Speaker 2: people to get a thorough assessment to know how to 173 00:09:32,559 --> 00:09:35,880 Speaker 2: start here. But I just I think a curious approach 174 00:09:35,920 --> 00:09:37,720 Speaker 2: is a helpful one at this stage in terms of 175 00:09:37,760 --> 00:09:38,280 Speaker 2: the research. 176 00:09:38,800 --> 00:09:42,800 Speaker 1: Yeah, look, there's many little rabbit holes that I'd like 177 00:09:42,840 --> 00:09:45,280 Speaker 1: to cook down in there, need to cook in myself. 178 00:09:45,320 --> 00:09:48,240 Speaker 1: But just the fact that you're talking about the whole 179 00:09:48,280 --> 00:09:52,520 Speaker 1: person approach. I mean, I've said many many times that 180 00:09:53,600 --> 00:09:58,160 Speaker 1: the way that we do Western science right that Newtonian 181 00:09:58,360 --> 00:10:03,360 Speaker 1: Cartesian waterview, you break things to smallest component part in 182 00:10:03,480 --> 00:10:06,760 Speaker 1: order to understand it. That can give us a really 183 00:10:06,800 --> 00:10:11,360 Speaker 1: good understanding about certain things and how things are made up. 184 00:10:11,480 --> 00:10:15,440 Speaker 1: But it misses the fact that we are a complex 185 00:10:15,480 --> 00:10:19,079 Speaker 1: ecosystem and that yes you have an immune system, and 186 00:10:19,120 --> 00:10:22,040 Speaker 1: yes you have a cardiovascular system and emphatic system, muscular 187 00:10:22,040 --> 00:10:27,240 Speaker 1: skeletal but they all interact with each other in ridiculously 188 00:10:27,360 --> 00:10:30,760 Speaker 1: complex ways. And this is the problem with people who 189 00:10:30,880 --> 00:10:34,319 Speaker 1: are real specialists in one area, Like when you're when 190 00:10:34,400 --> 00:10:37,920 Speaker 1: you're a hammer, everything looks like a neil. Yeah, yeah, 191 00:10:38,080 --> 00:10:44,360 Speaker 1: But I think that that complexity of the human condition 192 00:10:45,080 --> 00:10:47,679 Speaker 1: is something that we've got to explore more and more 193 00:10:47,720 --> 00:10:48,280 Speaker 1: and more. 194 00:10:48,360 --> 00:10:50,840 Speaker 2: Right, Yeah, yeah, yeah. I think it's moving from being 195 00:10:51,000 --> 00:10:54,880 Speaker 2: like the mechanical engineer kind of perspective or lens across 196 00:10:54,880 --> 00:10:57,800 Speaker 2: to like a gardener type lens where there's seasons and 197 00:10:58,280 --> 00:11:03,079 Speaker 2: growth is possible, and kind of just shifting that perspective 198 00:11:03,120 --> 00:11:06,400 Speaker 2: on the human body. It changes everything really because you 199 00:11:06,440 --> 00:11:10,120 Speaker 2: start just viewing all the different feelings you have, Like 200 00:11:10,160 --> 00:11:12,920 Speaker 2: pain is one of the best protectors that we've got 201 00:11:12,960 --> 00:11:16,199 Speaker 2: in terms of these invisible protective feelings we have, but 202 00:11:16,320 --> 00:11:20,079 Speaker 2: like fatigue and nausea and worrying, and we've got other 203 00:11:20,120 --> 00:11:23,560 Speaker 2: ways of keeping our body safe. And it's just an 204 00:11:23,600 --> 00:11:26,800 Speaker 2: interesting one to start classifying pain in that way because 205 00:11:26,800 --> 00:11:30,280 Speaker 2: you start zooming out from the body part and I 206 00:11:30,320 --> 00:11:33,320 Speaker 2: think that can be a helpful exercise in itself. But 207 00:11:33,360 --> 00:11:35,600 Speaker 2: it's not a one size fits all. That's the other 208 00:11:35,800 --> 00:11:39,080 Speaker 2: challenge here is that for some people they just go, well, 209 00:11:39,120 --> 00:11:41,520 Speaker 2: I've treated my body an engineer in my whole life, 210 00:11:42,000 --> 00:11:44,360 Speaker 2: and it kind of works, and the coping strategies are 211 00:11:44,360 --> 00:11:46,960 Speaker 2: within that realm, and so you don't want to like 212 00:11:47,200 --> 00:11:49,640 Speaker 2: throw the baby out with the bath water either way here. 213 00:11:50,520 --> 00:11:53,679 Speaker 2: But yeah, I totally agree that there's value in not 214 00:11:54,000 --> 00:11:57,160 Speaker 2: just zooming down and breaking everything into really small parts, 215 00:11:57,200 --> 00:12:00,320 Speaker 2: but also kind of looking at the ecosystem as a whole. 216 00:12:00,880 --> 00:12:04,520 Speaker 1: Yeah. Absolutely. And the interesting thing you said there about 217 00:12:05,000 --> 00:12:10,280 Speaker 1: the protection mechanism, I think there's a very clear link 218 00:12:10,400 --> 00:12:15,679 Speaker 1: there with chronic pain and some chronic mental health conditions 219 00:12:16,120 --> 00:12:21,840 Speaker 1: were there can be an oversensitization of of the amygdala 220 00:12:22,559 --> 00:12:28,720 Speaker 1: causing that that hyper sensitive, hyper vigilant threat state that 221 00:12:28,840 --> 00:12:32,440 Speaker 1: people then start to ruminate it a lot and can 222 00:12:32,520 --> 00:12:36,600 Speaker 1: cause anxiety and depression and and and often it's just 223 00:12:36,679 --> 00:12:40,200 Speaker 1: an overprotective mechanism. And you know, even think about things 224 00:12:40,240 --> 00:12:45,560 Speaker 1: like PTSD can just be that real protective mechanism that's 225 00:12:45,679 --> 00:12:49,040 Speaker 1: gone awry and then causes a whole heap of issues, 226 00:12:50,200 --> 00:12:54,160 Speaker 1: just like as you described this, this this chronic pain 227 00:12:54,400 --> 00:12:59,440 Speaker 1: can be a protective mechanism that is turned maladaptive rather 228 00:12:59,440 --> 00:13:00,720 Speaker 1: than adapt great. 229 00:13:00,800 --> 00:13:02,960 Speaker 2: Yeah, yeah, I agree. And I think those kind of 230 00:13:03,040 --> 00:13:07,960 Speaker 2: central mechanisms where like the MAP is influencing things and 231 00:13:08,240 --> 00:13:11,440 Speaker 2: the HPA acxis like all those stress autonomic nervous system. 232 00:13:11,559 --> 00:13:14,200 Speaker 2: There's a lot of overlap in the literature between all 233 00:13:14,240 --> 00:13:18,040 Speaker 2: these different conditions. But what often happens like and as 234 00:13:18,080 --> 00:13:22,600 Speaker 2: a physiotherapist early in the kind of post injury or 235 00:13:22,640 --> 00:13:25,760 Speaker 2: early in the disease phase, when it hasn't the volume 236 00:13:25,800 --> 00:13:28,480 Speaker 2: hasn't been turned up too much yet, it's not overprotective 237 00:13:28,640 --> 00:13:32,160 Speaker 2: yet all of most of the drivers seem to be peripheral, 238 00:13:32,240 --> 00:13:34,960 Speaker 2: and so people go and see a health professional and 239 00:13:35,000 --> 00:13:37,200 Speaker 2: it's like, Oh, I've sprained my ankle or I've hurt 240 00:13:37,200 --> 00:13:38,920 Speaker 2: my knee or whatever it is, and we start at 241 00:13:38,920 --> 00:13:41,560 Speaker 2: the knee and we look at it from that perspective, 242 00:13:42,000 --> 00:13:44,160 Speaker 2: and then it's like once you cross this point at 243 00:13:44,200 --> 00:13:47,040 Speaker 2: which oh, the body part's probably healed by now, then 244 00:13:47,080 --> 00:13:49,240 Speaker 2: we start looking at the top down approach and going, oh, 245 00:13:49,240 --> 00:13:50,920 Speaker 2: what else is going on? But I think we need 246 00:13:50,960 --> 00:13:53,360 Speaker 2: to do both all the time. And it's like, okay, 247 00:13:53,360 --> 00:13:56,800 Speaker 2: so peripheral sensitization is kicking in within forty eight hours 248 00:13:56,840 --> 00:13:59,400 Speaker 2: sort of thing like there's a lot of mechanisms happening 249 00:13:59,440 --> 00:14:03,840 Speaker 2: locally in the sore body part that could be amplified 250 00:14:03,960 --> 00:14:07,400 Speaker 2: and kind of driving a long term pain experience, but 251 00:14:07,440 --> 00:14:10,280 Speaker 2: then equally at the spinal cord, there's that chemical transaction 252 00:14:10,400 --> 00:14:12,280 Speaker 2: happening at the DG and then it gets into the 253 00:14:12,280 --> 00:14:15,800 Speaker 2: spinal cord and goes up more kind of highway lanes 254 00:14:15,840 --> 00:14:18,599 Speaker 2: going up the spinal cord can amplify that message. And 255 00:14:19,200 --> 00:14:22,840 Speaker 2: then even just some of Professor Mark Hutchinson's work on 256 00:14:23,200 --> 00:14:26,480 Speaker 2: the number of pathways that a no susceptive message can take, 257 00:14:26,840 --> 00:14:30,440 Speaker 2: it's like a out numbers even just at one level, 258 00:14:31,080 --> 00:14:33,120 Speaker 2: it's more than the number of stars in the universe, 259 00:14:33,160 --> 00:14:34,840 Speaker 2: like the number of pathways it can take. 260 00:14:35,760 --> 00:14:36,640 Speaker 1: And so like the. 261 00:14:36,640 --> 00:14:40,520 Speaker 2: Complexity of every single pain experience is just like absolutely 262 00:14:40,640 --> 00:14:43,640 Speaker 2: enormous because that's a danger message then being that could 263 00:14:43,640 --> 00:14:45,760 Speaker 2: be amplified or not. And then when it gets to 264 00:14:45,800 --> 00:14:47,800 Speaker 2: the brain at the mid brain, it can be amplified 265 00:14:47,920 --> 00:14:50,160 Speaker 2: or not. And then in the brain there's like so 266 00:14:50,240 --> 00:14:53,400 Speaker 2: many different parts of the brain that are active in 267 00:14:53,640 --> 00:14:56,680 Speaker 2: kind of determining whether or not to protect by pain. 268 00:14:57,640 --> 00:14:59,840 Speaker 2: And it's like hundreds it's not just like, oh, there's 269 00:14:59,840 --> 00:15:01,640 Speaker 2: this part of the brain that always happens, and if 270 00:15:01,640 --> 00:15:03,040 Speaker 2: we cut that part of the brain out, then no 271 00:15:03,080 --> 00:15:07,120 Speaker 2: one would feel pain. It's so complex and unique and 272 00:15:08,000 --> 00:15:11,040 Speaker 2: it's moment by moment. It's not like, oh, Paul today, 273 00:15:11,200 --> 00:15:14,520 Speaker 2: this part of your brain is the main driver. Like 274 00:15:14,560 --> 00:15:17,240 Speaker 2: I think, it's all these little percentages adding up and 275 00:15:17,280 --> 00:15:20,560 Speaker 2: compounding over time. And this is where we see, like 276 00:15:21,120 --> 00:15:24,400 Speaker 2: some of the latest evidence to treat chronic pain is 277 00:15:24,480 --> 00:15:28,280 Speaker 2: things like cognitive functional therapy where you're constantly kind of 278 00:15:28,360 --> 00:15:32,520 Speaker 2: challenging the nervous system in a graded exposure kind of approach, 279 00:15:32,600 --> 00:15:36,720 Speaker 2: but it's really really gradual and you're you're like tackling 280 00:15:36,720 --> 00:15:40,240 Speaker 2: fears head on. And some of these things are just super. 281 00:15:40,000 --> 00:15:46,960 Speaker 1: Challenging, like exposure therapy for anxiety, rightd greated exposure to 282 00:15:47,120 --> 00:15:49,480 Speaker 1: the thing that is causing the discomfort. 283 00:15:49,840 --> 00:15:53,080 Speaker 2: Yes, but like yeah, there's a few caveats because you 284 00:15:53,080 --> 00:15:54,840 Speaker 2: want to make sure that you're not going to be 285 00:15:54,880 --> 00:15:57,440 Speaker 2: causing damage, Like if someone has a tumor or something 286 00:15:57,480 --> 00:15:59,880 Speaker 2: going on, you don't want to be flaring those kinds 287 00:15:59,920 --> 00:16:03,800 Speaker 2: of things up. But that's once someone's had the assessment 288 00:16:03,800 --> 00:16:06,320 Speaker 2: and you know that it's safe to move, then you 289 00:16:06,360 --> 00:16:09,680 Speaker 2: can engage in these these kind of behavioral treatments that 290 00:16:09,760 --> 00:16:13,119 Speaker 2: have some pretty good evidence behind them for long term outcomes. 291 00:16:13,560 --> 00:16:16,200 Speaker 2: There's plenty of treatments people can get for short term 292 00:16:16,240 --> 00:16:20,320 Speaker 2: benefit and like, arguably you don't even know how much 293 00:16:20,360 --> 00:16:22,640 Speaker 2: of it is expectation and things yet because there's a 294 00:16:22,640 --> 00:16:26,920 Speaker 2: lot of studies. There's a colleague, Felicity Braithwait in Adelaide 295 00:16:27,000 --> 00:16:30,800 Speaker 2: Chi did this really cool study and they made a 296 00:16:30,880 --> 00:16:35,120 Speaker 2: sham dry needle and the assess the person doing the 297 00:16:35,200 --> 00:16:38,240 Speaker 2: dry needling couldn't tell like it clicked, and they couldn't 298 00:16:38,240 --> 00:16:40,120 Speaker 2: tell if the needle was penetrating the skin or not, 299 00:16:40,480 --> 00:16:42,280 Speaker 2: and the outcomes were the same. And so like in 300 00:16:42,320 --> 00:16:45,000 Speaker 2: an acute pain setting, if people want short term relief, 301 00:16:45,400 --> 00:16:47,440 Speaker 2: I think it's just let's just weigh up the benefits 302 00:16:47,520 --> 00:16:50,240 Speaker 2: versus the risks, but don't pay too much money for it. 303 00:16:50,440 --> 00:16:52,920 Speaker 2: But if you want long term benefits, like we want 304 00:16:52,920 --> 00:16:55,520 Speaker 2: to be looking at strategies that people can get back 305 00:16:55,520 --> 00:16:57,920 Speaker 2: to doing the stuff they love. And it's not like 306 00:16:57,960 --> 00:17:00,160 Speaker 2: we can guarantee that pain's going to go away. In 307 00:17:00,200 --> 00:17:03,080 Speaker 2: a lot of people, it does decrease, but in most 308 00:17:03,160 --> 00:17:05,960 Speaker 2: people we can get back to doing the stuff that 309 00:17:06,000 --> 00:17:09,639 Speaker 2: they love doing. And I think that's our current benchmark 310 00:17:09,720 --> 00:17:12,520 Speaker 2: of what we want to achieve. But yeah, it all 311 00:17:12,560 --> 00:17:16,520 Speaker 2: comes down like I think understanding this sensitization. The mechanisms 312 00:17:16,520 --> 00:17:19,880 Speaker 2: that are happening at a cellular level does inform all 313 00:17:19,880 --> 00:17:21,840 Speaker 2: of the approaches. Like when you were saying about like 314 00:17:22,080 --> 00:17:24,520 Speaker 2: if you were to do exercises of the sore body part, 315 00:17:24,880 --> 00:17:28,080 Speaker 2: it's like, what's happening locally with your drawing you mentioned 316 00:17:28,080 --> 00:17:30,879 Speaker 2: like inflammation and redness, Like what's happening at that level, 317 00:17:31,359 --> 00:17:33,879 Speaker 2: but also like what's happening can we change the math 318 00:17:33,920 --> 00:17:37,040 Speaker 2: and how does that all work? I think we need 319 00:17:37,080 --> 00:17:39,760 Speaker 2: to have that broader picture in mind the whole way 320 00:17:39,840 --> 00:17:44,280 Speaker 2: through the patient journey, rather than it being oh, yeah, 321 00:17:44,320 --> 00:17:46,320 Speaker 2: you've just got to learn the neuroscience or like kind 322 00:17:46,320 --> 00:17:50,359 Speaker 2: of oversimplifying any of these steps. I think what some 323 00:17:50,400 --> 00:17:52,920 Speaker 2: of the research that I read recently is about validating 324 00:17:53,000 --> 00:17:57,119 Speaker 2: and making sure the person who's challenged by pain is 325 00:17:57,240 --> 00:18:01,840 Speaker 2: truly heard, like and feels support to engage in this. 326 00:18:02,080 --> 00:18:04,639 Speaker 2: And I think it makes a lot of biological sense 327 00:18:04,720 --> 00:18:10,000 Speaker 2: because if it's it pains about threat and danger, you 328 00:18:10,119 --> 00:18:13,520 Speaker 2: need to be supported and feel safe in the space 329 00:18:13,600 --> 00:18:16,000 Speaker 2: that you're going to kind of move forward in. But 330 00:18:16,040 --> 00:18:18,199 Speaker 2: if you've just been told by person after person that 331 00:18:18,480 --> 00:18:21,000 Speaker 2: there is no way forward and you must have a surgery, 332 00:18:21,040 --> 00:18:22,800 Speaker 2: and you must do this, and you must, must, must. 333 00:18:23,080 --> 00:18:25,840 Speaker 2: It's such a passive receipt, like you're kind of the 334 00:18:25,880 --> 00:18:28,320 Speaker 2: passenger on a train to wherever and you don't know 335 00:18:29,440 --> 00:18:33,480 Speaker 2: versus like the evidence in favor of active supported self 336 00:18:33,520 --> 00:18:37,080 Speaker 2: management strategies. It's a much clearer kind of path forward. 337 00:18:37,119 --> 00:18:40,200 Speaker 1: I think I want to diet. This cheesus so much. 338 00:18:40,320 --> 00:18:44,040 Speaker 1: These yeah, that we can dive into a couple of 339 00:18:44,080 --> 00:18:48,160 Speaker 1: little diversions. So the one thing about that the support 340 00:18:48,200 --> 00:18:52,080 Speaker 1: of We know that in many things, not just pain, 341 00:18:52,280 --> 00:18:56,879 Speaker 1: but in many things that one of the biggest determinants 342 00:18:56,920 --> 00:19:00,920 Speaker 1: of the outcome is the strength of the therapeutic release ship. Right, 343 00:19:01,320 --> 00:19:05,640 Speaker 1: So whether it's in psychotherapy or whether it's even cardiology. 344 00:19:05,680 --> 00:19:07,760 Speaker 1: So we'll give you a great one from cardiology. So 345 00:19:07,840 --> 00:19:11,480 Speaker 1: cardiologists who come in somebody say, I'm in my fifties, 346 00:19:11,560 --> 00:19:15,280 Speaker 1: I've had a heart attack, I'm as fit ly as 347 00:19:15,600 --> 00:19:19,280 Speaker 1: I overrate a smoke. Cardiologists who come in and they've 348 00:19:19,280 --> 00:19:23,480 Speaker 1: actually done randomized control trials on this, come in and go, Paul, 349 00:19:23,880 --> 00:19:26,080 Speaker 1: you're fat, You're out of ship. That's why you've had 350 00:19:26,080 --> 00:19:28,000 Speaker 1: a heart attack. You need to change your diet, you 351 00:19:28,040 --> 00:19:31,240 Speaker 1: need to stop smoking, you need to reduce your drinking 352 00:19:31,359 --> 00:19:34,840 Speaker 1: and you need to get fit. Right, the impact on 353 00:19:34,920 --> 00:19:38,439 Speaker 1: the patient that, like, the chances of me making all 354 00:19:38,440 --> 00:19:42,440 Speaker 1: those lifestyle changes are so slim compared to a cardiologist 355 00:19:42,480 --> 00:19:45,600 Speaker 1: who uses motivational interviewing, Yeah, which is just one technique 356 00:19:45,680 --> 00:19:49,160 Speaker 1: right where they sit down and said to me, Okay, 357 00:19:49,600 --> 00:19:52,000 Speaker 1: how'd you get here? You tell me, and I kind 358 00:19:52,000 --> 00:19:54,919 Speaker 1: of go, well, that's kind of smoke too much. I drink, 359 00:19:55,400 --> 00:19:58,399 Speaker 1: you know, I don't exercise my dad shit, Okay, what 360 00:19:58,440 --> 00:20:00,320 Speaker 1: do you think you could do about it? Well, maybe 361 00:20:00,359 --> 00:20:02,960 Speaker 1: I should actually start extra That's a great idea, right, 362 00:20:03,400 --> 00:20:07,280 Speaker 1: Using that motivational interviewing with you say, the patient feels 363 00:20:07,320 --> 00:20:12,439 Speaker 1: heard but also has some autonomy and the treatment process 364 00:20:12,840 --> 00:20:16,960 Speaker 1: I think is really really key. So that's one thing 365 00:20:17,119 --> 00:20:19,760 Speaker 1: that I think you just mentioned that I want to 366 00:20:19,760 --> 00:20:24,760 Speaker 1: open people's eyes to. But then that expectation effect, right, 367 00:20:25,200 --> 00:20:29,240 Speaker 1: so we know with the placebo effect that big pills 368 00:20:29,240 --> 00:20:32,760 Speaker 1: are better than little pills, that capsules are better than pills, 369 00:20:33,320 --> 00:20:37,440 Speaker 1: that needles are better than capsules, and that sham surgery 370 00:20:37,840 --> 00:20:41,720 Speaker 1: is more effective than a needle, more effective than all them. 371 00:20:42,320 --> 00:20:48,280 Speaker 1: The biggest one for me was a Harvard osteopathic surgeon 372 00:20:48,840 --> 00:20:52,680 Speaker 1: who people with chronic back pain and they often get 373 00:20:52,720 --> 00:20:55,040 Speaker 1: spinal fusion. You'll be aware of this, right, And there's 374 00:20:55,119 --> 00:21:00,439 Speaker 1: about a fifty percent or so recovery real from that 375 00:21:00,600 --> 00:21:05,840 Speaker 1: chronic paean. But he did a bunch of chalm surgeries 376 00:21:06,160 --> 00:21:09,800 Speaker 1: where he pretended that he did the surgery to fuse 377 00:21:09,880 --> 00:21:13,440 Speaker 1: people's desks. They even created little punctures on them. They 378 00:21:13,480 --> 00:21:18,359 Speaker 1: give them afterwards, they give them Champian medication when they 379 00:21:18,400 --> 00:21:20,119 Speaker 1: come out of it. And it had a both to 380 00:21:20,240 --> 00:21:24,240 Speaker 1: seame success for it as the real surgery, right. So 381 00:21:24,840 --> 00:21:30,560 Speaker 1: that just shows that expectation effect. It's the whole Placeboar effect, right. 382 00:21:31,160 --> 00:21:33,680 Speaker 2: Yeah, and it's not I guess one thing that can 383 00:21:33,680 --> 00:21:36,080 Speaker 2: come up when you talk about this stuff. And Ian 384 00:21:36,160 --> 00:21:39,680 Speaker 2: Harris is a doctor in Australia and David Anderson. There's 385 00:21:39,720 --> 00:21:43,360 Speaker 2: a few researchers doing these kind of studies because they've 386 00:21:43,440 --> 00:21:46,600 Speaker 2: worked in like conditions like slap lesions of the shoulder 387 00:21:46,800 --> 00:21:51,439 Speaker 2: and nearthrooscopies and these sham surgeries. It's so fascinating. But 388 00:21:51,520 --> 00:21:53,919 Speaker 2: if you talk about this with someone who's facing the 389 00:21:54,000 --> 00:21:56,880 Speaker 2: challenges of chronic pain, and it's individual and it's horrible, 390 00:21:56,920 --> 00:21:59,960 Speaker 2: and it's terrible it can come across like saying, come on, 391 00:22:00,000 --> 00:22:02,720 Speaker 2: and you've just got to change your expectation and it's 392 00:22:02,760 --> 00:22:04,720 Speaker 2: all in your head. And I think that can be 393 00:22:04,800 --> 00:22:08,280 Speaker 2: so dismissive. And so I'm really conscious that I'm on 394 00:22:08,320 --> 00:22:10,119 Speaker 2: a podcast and we're talking about this stuff and there 395 00:22:10,200 --> 00:22:12,359 Speaker 2: might be people listening, Like the odds are that people 396 00:22:12,400 --> 00:22:15,119 Speaker 2: are listening who have pain, because the title of the 397 00:22:15,119 --> 00:22:18,000 Speaker 2: podcast probably has the word pain in it, and I 398 00:22:18,080 --> 00:22:20,159 Speaker 2: just don't want people to hear that. It's like that. 399 00:22:20,240 --> 00:22:24,199 Speaker 2: I don't think just changing expectations is sufficient, but in 400 00:22:24,280 --> 00:22:28,720 Speaker 2: saying that, strategies like motivational interviewing are really really appropriate 401 00:22:28,760 --> 00:22:31,679 Speaker 2: and effective, I think in getting that starting point. So 402 00:22:31,920 --> 00:22:34,359 Speaker 2: there's a tension there, and I think the pain is 403 00:22:34,480 --> 00:22:38,080 Speaker 2: real and the effect of the sham surgery is still real. 404 00:22:38,680 --> 00:22:42,159 Speaker 2: It's just that the mechanisms at play aren't. What like, 405 00:22:42,200 --> 00:22:44,240 Speaker 2: there's a bit of deception going on, right in a 406 00:22:44,280 --> 00:22:45,280 Speaker 2: sham surgery study. 407 00:22:46,160 --> 00:22:48,680 Speaker 1: Yeah, sorry, I just to clarify, I'm not for one 408 00:22:48,760 --> 00:22:52,080 Speaker 1: minute and suggesting that with any of these interventions are 409 00:22:52,119 --> 00:22:55,920 Speaker 1: perceive that it's bullshit. It's a real effect, right, Ye, great, 410 00:22:55,960 --> 00:23:01,399 Speaker 1: And you can't change people's expectations expectations. Well maybe you 411 00:23:01,400 --> 00:23:04,000 Speaker 1: could with a little bit of education, right, But their 412 00:23:04,040 --> 00:23:08,040 Speaker 1: expectations are their expectations. But it's just good. I think 413 00:23:08,040 --> 00:23:11,480 Speaker 1: it's kind of reinforcing your what you talked about earlier 414 00:23:11,520 --> 00:23:16,560 Speaker 1: with the whole person approach. And if someone believes that 415 00:23:16,600 --> 00:23:19,320 Speaker 1: an intervention is going to help and has a good 416 00:23:19,359 --> 00:23:25,080 Speaker 1: relationship with the whoever, the physician or the physiotherapist or whatever, 417 00:23:25,760 --> 00:23:31,440 Speaker 1: that optimizes the chances of success. And Jesus, there's probably 418 00:23:31,960 --> 00:23:36,639 Speaker 1: so many unexplored mechanisms that are going on throughout the 419 00:23:36,680 --> 00:23:42,280 Speaker 1: body and throughout the nervous system to drive that expectation effect. 420 00:23:42,280 --> 00:23:46,040 Speaker 1: I don't think it's just in your mind. I'm sure 421 00:23:46,160 --> 00:23:49,480 Speaker 1: when people really start to tease it apart that the 422 00:23:49,600 --> 00:23:54,119 Speaker 1: expectation effect is having a physiological impact somewhere. 423 00:23:53,800 --> 00:23:56,400 Speaker 2: Definitely, And I think, like so one of my phdtions, 424 00:23:56,400 --> 00:23:59,199 Speaker 2: we're looking at the therapeutic relationship in the context of 425 00:23:59,280 --> 00:24:02,640 Speaker 2: kids chronic pain where there's the parent involved, and that 426 00:24:02,720 --> 00:24:08,199 Speaker 2: dynamic between child, parent and clinician hasn't really been looked at, 427 00:24:08,240 --> 00:24:09,760 Speaker 2: and we're gonna set up we're setting up at the 428 00:24:09,760 --> 00:24:12,320 Speaker 2: moment the study. We haven't done it yet, but filming 429 00:24:12,359 --> 00:24:15,399 Speaker 2: these interactions and looking at the behaviors that do have 430 00:24:15,440 --> 00:24:19,200 Speaker 2: an impact and don't have an impact on outcomes, because 431 00:24:19,240 --> 00:24:22,240 Speaker 2: I think like even positioning, like if you're sitting straight 432 00:24:22,280 --> 00:24:24,920 Speaker 2: across from someone and there's a big desk in the way, 433 00:24:25,200 --> 00:24:29,640 Speaker 2: versus sitting alongside them and facing the same direction. There's 434 00:24:29,680 --> 00:24:32,360 Speaker 2: so much research on that kind of like the threatening 435 00:24:32,400 --> 00:24:34,720 Speaker 2: behaviors and the white code effect and all of those 436 00:24:34,800 --> 00:24:37,320 Speaker 2: kinds of things that I think, I guess all of 437 00:24:37,320 --> 00:24:42,240 Speaker 2: that for me plays into quantifying how much of a 438 00:24:42,320 --> 00:24:47,200 Speaker 2: power dynamic is there, like to actually change people's expectations, 439 00:24:47,200 --> 00:24:49,480 Speaker 2: because I know, like when I disliocated my shoulder and 440 00:24:49,520 --> 00:24:51,679 Speaker 2: I saw a surgeon to discuss whether or not to 441 00:24:51,720 --> 00:24:55,480 Speaker 2: get surgery. I went into that appointment, my back's drenched 442 00:24:55,520 --> 00:24:58,600 Speaker 2: in sweat, and You're like, what's he going to say? 443 00:24:59,320 --> 00:25:01,480 Speaker 2: And what is SCAN say? And this was when I 444 00:25:01,600 --> 00:25:04,040 Speaker 2: first became a physio. I thought I had magic hands. 445 00:25:04,040 --> 00:25:07,480 Speaker 2: Everything was very biomedical and structural, and so it was 446 00:25:07,480 --> 00:25:10,840 Speaker 2: a really big challenge for me to go like, now 447 00:25:10,880 --> 00:25:13,080 Speaker 2: I look at that, and I go, wow, Like whatever 448 00:25:13,359 --> 00:25:17,840 Speaker 2: that surgeon said would probably trump anything that I read 449 00:25:17,880 --> 00:25:20,719 Speaker 2: in the research, because it was like, like there's just 450 00:25:20,760 --> 00:25:25,320 Speaker 2: such a power imbalance of knowledge and of our society, 451 00:25:25,560 --> 00:25:27,399 Speaker 2: the perspective of a surgeon and all of that kind 452 00:25:27,440 --> 00:25:30,000 Speaker 2: of stuff, and that can happen at every level. And 453 00:25:30,520 --> 00:25:33,040 Speaker 2: some of my research with kids that even happens between 454 00:25:33,080 --> 00:25:36,600 Speaker 2: parents or grandparents, or like if one parent's saying one 455 00:25:36,640 --> 00:25:39,760 Speaker 2: thing and saying be careful where velcrow shoes don't bend, 456 00:25:40,040 --> 00:25:42,440 Speaker 2: and the other parents saying, come on, play rugby league 457 00:25:42,480 --> 00:25:45,520 Speaker 2: and get back to school, and like, those mixed messages 458 00:25:45,760 --> 00:25:49,520 Speaker 2: are so unlike, so challenging for a child's developing nervous 459 00:25:49,560 --> 00:25:52,760 Speaker 2: system to have to try and weigh up. And so 460 00:25:52,800 --> 00:25:55,920 Speaker 2: I think for me, it's like that, let's work out 461 00:25:56,000 --> 00:25:58,679 Speaker 2: what what can we do what like because maybe we 462 00:25:58,720 --> 00:26:02,439 Speaker 2: can change expectations for the whole next generation. And I 463 00:26:02,520 --> 00:26:05,880 Speaker 2: make a comparison with this kind of idea of preventative education. 464 00:26:06,760 --> 00:26:09,159 Speaker 2: If we go like in the nineteen eighties in Australia 465 00:26:09,160 --> 00:26:11,359 Speaker 2: we did slip, slop, slap, and now like I have 466 00:26:11,440 --> 00:26:13,760 Speaker 2: young kids and they wear hats and sunscreen and the 467 00:26:13,800 --> 00:26:17,719 Speaker 2: behaviors have changed. We have colored lids on our bins. 468 00:26:17,960 --> 00:26:21,439 Speaker 2: We do in Sydney anyway, and recycling is a normal 469 00:26:21,440 --> 00:26:23,720 Speaker 2: behavior when it wasn't a normal behavior a couple of 470 00:26:23,800 --> 00:26:26,920 Speaker 2: generations ago, And I like my dream with this research 471 00:26:27,000 --> 00:26:29,600 Speaker 2: is what are those behaviors that we could instill in 472 00:26:29,640 --> 00:26:33,000 Speaker 2: the next generation to try to counter some of these 473 00:26:33,440 --> 00:26:36,320 Speaker 2: kind of huge like I mean pain costs Australia, Like 474 00:26:36,359 --> 00:26:38,119 Speaker 2: I think it was one hundred and thirty nine billion 475 00:26:38,160 --> 00:26:41,439 Speaker 2: dollars a year or some ridiculous number, And it's like, 476 00:26:41,480 --> 00:26:44,000 Speaker 2: could we not only reduce the financial cost but the 477 00:26:44,040 --> 00:26:49,320 Speaker 2: societal burdens of chronic pain. I think if the research 478 00:26:49,440 --> 00:26:53,760 Speaker 2: just seems so far ahead of the societal misconceptions about like, oh, 479 00:26:53,800 --> 00:26:57,040 Speaker 2: more pain must mean more damage, and they're like pain 480 00:26:57,160 --> 00:26:59,439 Speaker 2: is a direct result of this, Whereas I think if 481 00:26:59,440 --> 00:27:03,199 Speaker 2: everyone aciated that there are so many things influencing and 482 00:27:03,320 --> 00:27:06,920 Speaker 2: changing the volume of every pain experience, they might start 483 00:27:06,960 --> 00:27:10,360 Speaker 2: thinking a bit more curiously about it and what we're 484 00:27:10,359 --> 00:27:12,800 Speaker 2: seeing in the school based studies we're doing. Even like 485 00:27:12,920 --> 00:27:14,960 Speaker 2: the principle of a school recently was like, oh, the 486 00:27:15,440 --> 00:27:18,120 Speaker 2: kids who don't have chronic pain are more empathetic now 487 00:27:18,119 --> 00:27:21,320 Speaker 2: that they've learnt this neuroscience. They're more caring and understanding. 488 00:27:21,520 --> 00:27:24,240 Speaker 2: There's less of this bullying going on of that poor 489 00:27:24,320 --> 00:27:28,760 Speaker 2: kid who is really struggling, and I find that really fascinating. 490 00:27:28,800 --> 00:27:32,920 Speaker 2: And we didn't expect that education about pain would help 491 00:27:33,119 --> 00:27:37,199 Speaker 2: kids who don't have pain, and that's it's yeah, And 492 00:27:37,240 --> 00:27:41,919 Speaker 2: I think, so we're stepping from going okay, like placebo 493 00:27:42,000 --> 00:27:45,439 Speaker 2: effects and these kind of everything has some sort of 494 00:27:45,440 --> 00:27:49,359 Speaker 2: biological underpinning potentially, and then we go we zoom out 495 00:27:49,359 --> 00:27:51,359 Speaker 2: and we go okay, so treatments can work for a 496 00:27:51,480 --> 00:27:53,800 Speaker 2: variety of reasons, and then we go, okay, well maybe 497 00:27:53,800 --> 00:27:57,320 Speaker 2: we could prevent things and change things. And so that's 498 00:27:57,400 --> 00:27:59,480 Speaker 2: kind of where I'm interested, is like, how do we 499 00:27:59,520 --> 00:28:05,240 Speaker 2: communicate all of this complexity to kind of everyone rather 500 00:28:05,280 --> 00:28:07,040 Speaker 2: than it just being oh, we're going to change one 501 00:28:07,119 --> 00:28:10,080 Speaker 2: university course or we're going to put one TV ad 502 00:28:10,119 --> 00:28:13,080 Speaker 2: out or something like that. And I think we should 503 00:28:13,119 --> 00:28:15,800 Speaker 2: do all of those things, but it's hard to know 504 00:28:15,840 --> 00:28:19,280 Speaker 2: what's going to help in this age where, yeah, like 505 00:28:19,320 --> 00:28:22,080 Speaker 2: how do we change society's behaviors at a big level 506 00:28:22,200 --> 00:28:25,200 Speaker 2: is kind of that big question I'm fascinated by. 507 00:28:26,480 --> 00:28:29,200 Speaker 1: Want I want to come back and talk about children, 508 00:28:29,240 --> 00:28:31,159 Speaker 1: because you do a lot of research on that, But 509 00:28:32,600 --> 00:28:36,800 Speaker 1: let's just do a little bit of education and let's 510 00:28:36,840 --> 00:28:41,840 Speaker 1: take the fourteen week course that you do for students 511 00:28:41,880 --> 00:28:46,240 Speaker 1: physiotherabal students. And let's take the PIN component and compress 512 00:28:46,280 --> 00:28:47,680 Speaker 1: it into about five minutes. 513 00:28:47,840 --> 00:28:50,120 Speaker 2: Okay, So just I. 514 00:28:50,080 --> 00:28:53,080 Speaker 1: Want people to get an understanding. You've mentioned a number 515 00:28:53,080 --> 00:28:55,960 Speaker 1: of the things that are important in the pein signal. 516 00:28:56,360 --> 00:29:00,800 Speaker 1: So let's just talk about the nervous system, the PAN receptors, 517 00:29:01,400 --> 00:29:05,600 Speaker 1: and they're all the way up and they're different areas 518 00:29:05,680 --> 00:29:09,520 Speaker 1: where that PAN can get amplified, ending up in the 519 00:29:09,560 --> 00:29:12,400 Speaker 1: Briand just so people can get an understanding of how 520 00:29:13,120 --> 00:29:16,080 Speaker 1: PAN actually works as much as we understand right now. 521 00:29:16,200 --> 00:29:18,160 Speaker 2: Yeah, yeah, yeah, And and I think like the starting 522 00:29:18,160 --> 00:29:21,880 Speaker 2: point would be to understand this word called nosyception. And often, 523 00:29:22,080 --> 00:29:25,280 Speaker 2: like if you go onto kids science books and I've 524 00:29:25,320 --> 00:29:28,520 Speaker 2: done this, it conflates like it says that pain is 525 00:29:28,560 --> 00:29:32,680 Speaker 2: because of nos reception, and like really just overlaps those 526 00:29:32,720 --> 00:29:38,120 Speaker 2: ideas way too much. Nos Reception is the encoding of 527 00:29:38,280 --> 00:29:42,400 Speaker 2: noxious stimuli is the technical words. It's it's about transmitting 528 00:29:42,480 --> 00:29:46,760 Speaker 2: a danger message. And I've made some kids books and 529 00:29:46,800 --> 00:29:48,440 Speaker 2: tried to convey that. And the way we did it 530 00:29:48,480 --> 00:29:51,200 Speaker 2: was it was like a virtual reality adventure inside the 531 00:29:51,240 --> 00:29:54,040 Speaker 2: brain and the body and there's like little envelopes going 532 00:29:54,080 --> 00:29:56,960 Speaker 2: everywhere in the body, so and no seception. Like, so 533 00:29:57,080 --> 00:30:00,800 Speaker 2: when a body part reaches the threat shold on these 534 00:30:00,880 --> 00:30:06,120 Speaker 2: nerve endings of either pressure, temperature, or a chemical change, 535 00:30:06,160 --> 00:30:08,120 Speaker 2: there's a point at which the no Si sceptor goes, 536 00:30:08,120 --> 00:30:10,880 Speaker 2: all right, there's enough danger here that I need to 537 00:30:10,960 --> 00:30:14,280 Speaker 2: let the next part of the body know. And so 538 00:30:14,320 --> 00:30:17,440 Speaker 2: then that message goes up the nerve and it can 539 00:30:17,920 --> 00:30:21,640 Speaker 2: like in that local area, more nerves can fire. And 540 00:30:21,680 --> 00:30:24,120 Speaker 2: so like you'll see when something swells, say, if you 541 00:30:24,120 --> 00:30:26,280 Speaker 2: have a body part the turning more and more like 542 00:30:26,320 --> 00:30:29,520 Speaker 2: the swelling might grow. That's more nerve receptors are now 543 00:30:29,600 --> 00:30:32,840 Speaker 2: sending up messages, right, and so it keeps growing exponentially, 544 00:30:33,880 --> 00:30:35,960 Speaker 2: and it's going there's enough danger here that we need 545 00:30:36,000 --> 00:30:39,440 Speaker 2: to do something about it. And so that gets to 546 00:30:39,480 --> 00:30:42,960 Speaker 2: the spinal cord. So the no seception message, the no 547 00:30:43,040 --> 00:30:46,040 Speaker 2: seceptive messages gets to the spinal cords. There's danger going 548 00:30:46,080 --> 00:30:49,320 Speaker 2: on here. So something's being touched or pushed or chemical 549 00:30:49,400 --> 00:30:51,720 Speaker 2: changes enough that there's a problem and we need to 550 00:30:51,800 --> 00:30:54,440 Speaker 2: let the brain know, Like let's let the central nervous 551 00:30:54,440 --> 00:30:58,120 Speaker 2: no and so then that nerve it's not like a 552 00:30:58,400 --> 00:31:01,120 Speaker 2: perfect wire that just goes directly to the brain. There's 553 00:31:01,160 --> 00:31:05,440 Speaker 2: that chemical transaction, and this is where it's just next 554 00:31:05,480 --> 00:31:08,800 Speaker 2: to your spinal cord, the dorsal root ganglion. At that point, 555 00:31:09,160 --> 00:31:11,959 Speaker 2: that's where all those different connections can happen. And then 556 00:31:12,000 --> 00:31:13,920 Speaker 2: there's the highways going up the spinal cord. 557 00:31:14,200 --> 00:31:17,160 Speaker 1: And how much a neural transmitter is involved at this junction. 558 00:31:17,560 --> 00:31:20,160 Speaker 2: Yeah, so at every so this is like a sign apse. 559 00:31:20,160 --> 00:31:22,080 Speaker 2: You might have heard of that term. Yes, so at 560 00:31:22,160 --> 00:31:26,400 Speaker 2: every kind of time that there's communication happening. We used 561 00:31:26,440 --> 00:31:29,600 Speaker 2: to think of glial cells like glial in Latin is 562 00:31:29,640 --> 00:31:31,920 Speaker 2: about glue. Like we used to think of them as 563 00:31:31,960 --> 00:31:35,040 Speaker 2: like a passive kind of structural they'll hold the neurons 564 00:31:35,040 --> 00:31:38,680 Speaker 2: in place and that, and that's kind of true. But 565 00:31:38,800 --> 00:31:43,040 Speaker 2: also glial cells have quite a big role in chronic 566 00:31:43,080 --> 00:31:46,920 Speaker 2: pain and pain this kind of idea of messaging of 567 00:31:47,000 --> 00:31:51,640 Speaker 2: danger systems, danger signals. And so when that chemical transaction 568 00:31:51,720 --> 00:31:55,720 Speaker 2: is happening, there's a whole lot of different external influences 569 00:31:55,720 --> 00:31:58,640 Speaker 2: that can happen. And so if we tried to make 570 00:31:58,680 --> 00:32:03,160 Speaker 2: the exact same chemical transaction happen, it would be very 571 00:32:03,280 --> 00:32:07,520 Speaker 2: very hard between people, that's for sure. Because the surrounding 572 00:32:07,840 --> 00:32:12,000 Speaker 2: nervous system is not identical. And so when people like 573 00:32:12,080 --> 00:32:14,040 Speaker 2: at the moment, there's researchers trying to go, oh, like 574 00:32:14,120 --> 00:32:17,040 Speaker 2: maybe we could shoot light in and do like optic 575 00:32:17,200 --> 00:32:20,120 Speaker 2: kind of treatments that are non invasive at that level, 576 00:32:20,520 --> 00:32:22,880 Speaker 2: and like there's just so many potential ways, Like there's 577 00:32:22,920 --> 00:32:25,560 Speaker 2: lots of opioids and different mechanisms that act on different 578 00:32:25,560 --> 00:32:28,920 Speaker 2: receptors that are nearby and in that area. So this 579 00:32:28,960 --> 00:32:32,040 Speaker 2: is all happening kind of at the spinal cord wherever 580 00:32:32,080 --> 00:32:34,640 Speaker 2: the nerve roote kind of enters the nervous system from 581 00:32:34,640 --> 00:32:36,320 Speaker 2: whatever the sore body part was. So if it was 582 00:32:36,360 --> 00:32:39,120 Speaker 2: your ankle, it's going in down the bottom of your back, 583 00:32:39,440 --> 00:32:41,320 Speaker 2: whereas if it was in your arm or your shoulder, 584 00:32:41,600 --> 00:32:43,960 Speaker 2: it would be up in your neck where this is happening. 585 00:32:44,440 --> 00:32:47,520 Speaker 1: So then this is the harndholding between the peripheral and 586 00:32:47,560 --> 00:32:48,680 Speaker 1: the central nervous system. 587 00:32:48,760 --> 00:32:50,960 Speaker 2: That's right, yes, And at that junction there's a lot 588 00:32:50,960 --> 00:32:53,640 Speaker 2: of potential where I guess the way that we explain 589 00:32:53,680 --> 00:32:56,000 Speaker 2: this with kids is like the volume of that message 590 00:32:56,040 --> 00:32:58,840 Speaker 2: could be louder or quieter. So in the envelope it 591 00:32:58,880 --> 00:33:02,360 Speaker 2: says danger, and it might lower case, but now the 592 00:33:02,400 --> 00:33:05,280 Speaker 2: message is capital D, A, N, G, er and like, 593 00:33:05,360 --> 00:33:08,520 Speaker 2: and it's stuck on the right and there's lots of 594 00:33:08,560 --> 00:33:13,080 Speaker 2: exclamation marks, and so the original message has already been modified. 595 00:33:13,120 --> 00:33:17,560 Speaker 2: It's like Australia Posts has changed the letter or there's 596 00:33:17,600 --> 00:33:21,160 Speaker 2: more letters and they're bigger envelopes at whatever it is. 597 00:33:21,240 --> 00:33:23,640 Speaker 2: And so by the time it gets to the brain, 598 00:33:23,920 --> 00:33:27,720 Speaker 2: it might not be exactly that same message. It's an 599 00:33:27,760 --> 00:33:31,200 Speaker 2: interpreted like it's kind of a modified message. And in 600 00:33:31,240 --> 00:33:33,600 Speaker 2: the nineteen sixties, even like we talk about this in 601 00:33:33,720 --> 00:33:37,880 Speaker 2: the in the course of the gate control theory kind 602 00:33:37,880 --> 00:33:40,280 Speaker 2: of got that bit of the physiology, right, I think 603 00:33:40,360 --> 00:33:43,440 Speaker 2: where there's there's had this idea of like different gates 604 00:33:43,480 --> 00:33:46,760 Speaker 2: where you could kind of allow messages up to the 605 00:33:46,800 --> 00:33:50,160 Speaker 2: brain or not. And I guess it's that threshold idea, 606 00:33:50,200 --> 00:33:52,400 Speaker 2: but I think we can we've moved past that. And 607 00:33:52,440 --> 00:33:54,440 Speaker 2: there's a lot of different theories on how this works. 608 00:33:54,480 --> 00:33:58,120 Speaker 2: But basically, the brain is then receiving these messages, and 609 00:33:58,160 --> 00:34:01,120 Speaker 2: it's got thoughts and memories and expects to deal with. 610 00:34:01,520 --> 00:34:03,920 Speaker 2: It's got the visual input if you've seen the body 611 00:34:03,920 --> 00:34:06,720 Speaker 2: part that saw or not. There's all these different things 612 00:34:06,720 --> 00:34:08,280 Speaker 2: that have happened, like have I had this before? 613 00:34:09,200 --> 00:34:12,080 Speaker 1: And then I just want to throw in there, Joshua 614 00:34:12,640 --> 00:34:17,520 Speaker 1: a quote from Ahmat Gotswami, who's an astrophysicist and philosopher. 615 00:34:18,040 --> 00:34:21,680 Speaker 1: We don't perceive reality directly. We perceive it through the 616 00:34:21,719 --> 00:34:22,680 Speaker 1: mirror of memory. 617 00:34:23,760 --> 00:34:26,400 Speaker 2: Yeah, okay, interesting, So if. 618 00:34:26,239 --> 00:34:31,240 Speaker 1: You've had the memory of pain there can actually change 619 00:34:31,280 --> 00:34:34,720 Speaker 1: how you're perceiving that message that's coming in, right. 620 00:34:34,560 --> 00:34:38,240 Speaker 2: And that If that sounds like gobbledygook or like pseudoscience 621 00:34:38,280 --> 00:34:42,720 Speaker 2: to anyone listening, check out Melanie Knowles work in Canada. 622 00:34:42,800 --> 00:34:46,360 Speaker 2: She's a professor there. They did some awesome studies on 623 00:34:46,640 --> 00:34:50,040 Speaker 2: vaccination pain and with kids they were able to reframe 624 00:34:50,719 --> 00:34:54,040 Speaker 2: the previous pain experience by saying things like, oh remember 625 00:34:54,080 --> 00:34:56,120 Speaker 2: last time when you got your needle, you got a 626 00:34:56,160 --> 00:35:00,200 Speaker 2: lolli and and they talk about all the positive parts 627 00:35:00,200 --> 00:35:03,720 Speaker 2: of the experience. Yes, and that reduces the next paint 628 00:35:04,120 --> 00:35:08,080 Speaker 2: in the future vaccinations. And to me, like that is 629 00:35:08,200 --> 00:35:11,960 Speaker 2: really exciting, Like the fact that reframing can have some 630 00:35:12,120 --> 00:35:16,960 Speaker 2: effect even is so cool and yes, so one hundred percent. 631 00:35:17,080 --> 00:35:19,600 Speaker 2: Like the posterior parietal cortex, like the part of your 632 00:35:19,600 --> 00:35:22,080 Speaker 2: brain where you're accessing and trying to work out how 633 00:35:22,160 --> 00:35:25,560 Speaker 2: is memory influencing it? This is all happening. All this 634 00:35:25,600 --> 00:35:27,640 Speaker 2: stuff I've been talking about for a few minutes is 635 00:35:27,680 --> 00:35:31,680 Speaker 2: in a split second, it's not right. Yeah, yeah, this 636 00:35:31,840 --> 00:35:33,439 Speaker 2: is like, so you put your hand on the hot 637 00:35:33,440 --> 00:35:36,880 Speaker 2: plate and maybe a memory from when you were three 638 00:35:37,280 --> 00:35:40,160 Speaker 2: is coming back of your grandma saying don't touch it 639 00:35:40,280 --> 00:35:44,919 Speaker 2: or something like this is this is hard to kind 640 00:35:44,920 --> 00:35:46,480 Speaker 2: of standardize in a study. 641 00:35:46,760 --> 00:35:49,400 Speaker 1: It's like my it's like my little guy Oscar stood 642 00:35:49,520 --> 00:35:54,240 Speaker 1: on one of those sea urchins when he was a kid, okay, 643 00:35:54,640 --> 00:35:57,440 Speaker 1: and then for years just wouldn't go into water, and 644 00:35:58,200 --> 00:36:01,080 Speaker 1: we didn't understand why. And then it was like, oh shit, right, 645 00:36:01,160 --> 00:36:07,640 Speaker 1: so there's he is remembering and associating that pin with 646 00:36:08,280 --> 00:36:08,720 Speaker 1: the seed. 647 00:36:09,320 --> 00:36:12,279 Speaker 2: Yes, that's right, and yeah, and I guess that's where 648 00:36:12,360 --> 00:36:14,480 Speaker 2: like fear and all of these other things are kind 649 00:36:14,480 --> 00:36:17,800 Speaker 2: of going to mediate that interpretation of all these danger 650 00:36:17,800 --> 00:36:20,920 Speaker 2: messages coming up because I still haven't even mentioned pain yet, Like, 651 00:36:21,280 --> 00:36:24,440 Speaker 2: had all this no suception happening, the ankle sprained, the 652 00:36:24,520 --> 00:36:28,000 Speaker 2: damages happened or not happened, But there's there's plenty of 653 00:36:28,040 --> 00:36:31,239 Speaker 2: messages going up, and then yeah, I guess that's like 654 00:36:31,520 --> 00:36:34,720 Speaker 2: there's all these other mechanisms going back down the nervous 655 00:36:34,719 --> 00:36:36,480 Speaker 2: system from the brain to the spinal cord to the 656 00:36:36,480 --> 00:36:39,479 Speaker 2: body part, and we call it things like if people 657 00:36:39,520 --> 00:36:43,040 Speaker 2: want to read like descending inhibition or you could, Yeah, 658 00:36:43,080 --> 00:36:45,319 Speaker 2: there's some stuff that lay language would be like top 659 00:36:45,360 --> 00:36:50,239 Speaker 2: down kind of modulation. And that's where I think for me, 660 00:36:50,560 --> 00:36:53,200 Speaker 2: like there's a lot of data in psychological treatment about 661 00:36:53,200 --> 00:36:56,160 Speaker 2: a sense of agency predicting good outcomes, like if you 662 00:36:56,200 --> 00:36:59,040 Speaker 2: have a sense of self efficacy and control over the condition, 663 00:36:59,880 --> 00:37:03,400 Speaker 2: or if the condition is controlling you, you tend to 664 00:37:03,400 --> 00:37:06,120 Speaker 2: go on a different trajectory. And that's why I think 665 00:37:06,360 --> 00:37:10,480 Speaker 2: learning some of this can help empower people to go, hey, 666 00:37:10,520 --> 00:37:13,520 Speaker 2: you know what, I can't control everything, but I can 667 00:37:13,680 --> 00:37:19,120 Speaker 2: control my breathing and so therefore I can control whatever 668 00:37:19,160 --> 00:37:23,440 Speaker 2: it is panic attacks or whatever, and that has an 669 00:37:23,480 --> 00:37:26,400 Speaker 2: indirect influence on my next pain experience, and that has 670 00:37:26,440 --> 00:37:31,000 Speaker 2: an indirect effect on my mood, which then reduces my 671 00:37:31,080 --> 00:37:34,280 Speaker 2: depression or whatever. Like you can see the web start 672 00:37:34,360 --> 00:37:37,520 Speaker 2: to build, and I think it's really hard to formulate 673 00:37:37,520 --> 00:37:40,400 Speaker 2: this without like an exact kind of case example that 674 00:37:40,440 --> 00:37:42,799 Speaker 2: we're all on the same page with. So people are 675 00:37:42,800 --> 00:37:46,120 Speaker 2: probably just projecting their own experiences right now, and that's fine, 676 00:37:46,760 --> 00:37:49,400 Speaker 2: but maybe you can start connecting the dots between like 677 00:37:50,120 --> 00:37:52,720 Speaker 2: your diet and your sleep and you're like just thinking 678 00:37:52,760 --> 00:37:55,160 Speaker 2: some some broader stuff is going to influence it. And 679 00:37:55,160 --> 00:37:58,239 Speaker 2: we know, for instance, like sleep, there was a great 680 00:37:58,280 --> 00:38:01,520 Speaker 2: study looking at the Bideck direction all effects, so like 681 00:38:01,719 --> 00:38:03,960 Speaker 2: if you have bad sleep, you're going to have worse 682 00:38:04,000 --> 00:38:06,360 Speaker 2: pain the next day, and if you have bad pain, 683 00:38:06,400 --> 00:38:08,640 Speaker 2: you're going to have worse sleep the next night. And 684 00:38:08,680 --> 00:38:11,800 Speaker 2: so just in the pain and sleep web, that cycle 685 00:38:11,920 --> 00:38:13,919 Speaker 2: is a vicious one and can get worse and worse 686 00:38:13,960 --> 00:38:17,560 Speaker 2: and worse pretty quickly. So even just the time that 687 00:38:17,600 --> 00:38:20,879 Speaker 2: you're on a waiting list for a sleep study, Like, yeah, 688 00:38:20,960 --> 00:38:23,880 Speaker 2: it's just a really hard thing. And that's just isolating 689 00:38:23,920 --> 00:38:27,560 Speaker 2: two variables, which is just an unbelievable simplification. 690 00:38:28,120 --> 00:38:31,200 Speaker 1: Yeah, I'm I'm going to throw another one into the 691 00:38:31,200 --> 00:38:33,759 Speaker 1: mix before we get to the brillin Right. Okay, you 692 00:38:33,880 --> 00:38:38,400 Speaker 1: mentioned that sense of agency. Yeah, that plays very strongly 693 00:38:38,440 --> 00:38:42,400 Speaker 1: into the psychology and internal lookers of control and external 694 00:38:42,400 --> 00:38:45,880 Speaker 1: looks and control and whole research on haartiness and whether 695 00:38:46,000 --> 00:38:49,360 Speaker 1: or not people high in hardiness or have a high 696 00:38:49,400 --> 00:38:53,279 Speaker 1: internal looks of control believe that they have a very 697 00:38:53,400 --> 00:38:57,640 Speaker 1: strong influence on their destiny and the heartiness research tools 698 00:38:57,680 --> 00:39:02,879 Speaker 1: that they recover better from operations from all these sorts 699 00:39:02,880 --> 00:39:05,040 Speaker 1: of things, whereas people with an external look as of 700 00:39:05,040 --> 00:39:08,360 Speaker 1: control they've got lower agency, They believe that they have 701 00:39:08,520 --> 00:39:13,160 Speaker 1: less influence of things, and they take a lot longer 702 00:39:13,239 --> 00:39:16,600 Speaker 1: to recover from operations and things like that. So I 703 00:39:16,640 --> 00:39:20,719 Speaker 1: think that the psychology plays in here in terms of 704 00:39:21,040 --> 00:39:25,800 Speaker 1: what my agency actually is. Do you know what I think? 705 00:39:26,040 --> 00:39:28,960 Speaker 2: Like there's some interesting research about like, oh, maybe knowledge 706 00:39:28,960 --> 00:39:32,040 Speaker 2: and belief change is not sufficient for behavior change, and 707 00:39:32,080 --> 00:39:34,839 Speaker 2: some of that kind of ideas really fascinating. And one 708 00:39:34,880 --> 00:39:37,560 Speaker 2: idea of been thinking about is with these physio students. 709 00:39:37,600 --> 00:39:39,960 Speaker 2: So I have like seventy five students. They've done an 710 00:39:40,040 --> 00:39:44,120 Speaker 2: undergraduate degree in like biomechanical type stuff, so they're thinking 711 00:39:44,320 --> 00:39:46,719 Speaker 2: about the body very structurally, and then they come to 712 00:39:46,760 --> 00:39:51,000 Speaker 2: this course and often in like somewhere between week four 713 00:39:51,040 --> 00:39:55,080 Speaker 2: and week eight, like the midway point, most of the 714 00:39:55,120 --> 00:39:58,560 Speaker 2: students start having this moment where they apply what they've 715 00:39:58,600 --> 00:40:02,200 Speaker 2: been learning to their own experience. And it's this weird 716 00:40:02,640 --> 00:40:05,480 Speaker 2: time where I get all these emails and after class, 717 00:40:05,480 --> 00:40:07,600 Speaker 2: people are going, hey, hey, I know you've been saying 718 00:40:07,640 --> 00:40:11,680 Speaker 2: this helps patients, but like for my pain, which and 719 00:40:11,719 --> 00:40:13,480 Speaker 2: then you can see that they're starting to go, oh, 720 00:40:13,520 --> 00:40:15,399 Speaker 2: when I'm at the gym and this happens, or when 721 00:40:15,440 --> 00:40:19,160 Speaker 2: I have headaches, this is what's going on. And I think, 722 00:40:19,360 --> 00:40:24,520 Speaker 2: thinking by a psychosocially, yes, it probably is actually increasing 723 00:40:24,600 --> 00:40:29,560 Speaker 2: agency because I mean, anecdotally, we've got data on people 724 00:40:29,719 --> 00:40:33,960 Speaker 2: shifting to having an internal locus of control and the like. 725 00:40:34,040 --> 00:40:37,719 Speaker 2: So at a student level, at a professional level, when 726 00:40:37,719 --> 00:40:41,280 Speaker 2: people learn this stuff, it seems to have personal benefits. 727 00:40:41,280 --> 00:40:42,960 Speaker 2: And I know that's true for me and a lot 728 00:40:43,000 --> 00:40:45,080 Speaker 2: of the researchers I work with who are like, oh, 729 00:40:45,120 --> 00:40:47,720 Speaker 2: we want everyone to have this same amount of knowledge. 730 00:40:48,680 --> 00:40:50,960 Speaker 2: And I guess that's where I'm really fascinated, is like, 731 00:40:51,000 --> 00:40:55,800 Speaker 2: what's the minimal dose of knowledge and belief change that's 732 00:40:55,800 --> 00:41:00,520 Speaker 2: sufficient to empower someone long long term? And you see 733 00:41:00,560 --> 00:41:04,560 Speaker 2: those people online, like there's this awesome lady on Instagram 734 00:41:04,600 --> 00:41:07,560 Speaker 2: who can do like backflips and handstands and really cool stuff, 735 00:41:07,560 --> 00:41:09,799 Speaker 2: and like that's the kind of old person that we 736 00:41:09,840 --> 00:41:12,279 Speaker 2: want everyone to be, right, Like these these kind of 737 00:41:12,320 --> 00:41:14,880 Speaker 2: active people who just having a blast, their whole life 738 00:41:14,960 --> 00:41:18,840 Speaker 2: seems great and maybe it's not. And but I think 739 00:41:19,400 --> 00:41:23,160 Speaker 2: having joy and relating that to movement and physical activity 740 00:41:23,239 --> 00:41:26,680 Speaker 2: just seems like a good a good target for us 741 00:41:26,719 --> 00:41:30,560 Speaker 2: to aim for rather than it being about aesthetics or 742 00:41:30,640 --> 00:41:33,800 Speaker 2: just to try and like cope with pain or whatever 743 00:41:33,840 --> 00:41:37,120 Speaker 2: that those other motivators are. But it's a really hard 744 00:41:37,160 --> 00:41:41,040 Speaker 2: thing to set our goals, like long long term goals. 745 00:41:41,960 --> 00:41:45,640 Speaker 2: But people with heartiness and internal lockers of control, they 746 00:41:45,680 --> 00:41:47,680 Speaker 2: seem to do that like they're not thinking in the 747 00:41:47,680 --> 00:41:50,120 Speaker 2: short or the medium term so much like they're not 748 00:41:50,160 --> 00:41:55,840 Speaker 2: thinking in hours or days, they're thinking in months and years. 749 00:41:54,880 --> 00:42:01,160 Speaker 1: And they also see things like in injury as a 750 00:42:01,239 --> 00:42:04,640 Speaker 1: challenge for them to overcome. Right, Yeah, And I think 751 00:42:04,680 --> 00:42:09,640 Speaker 1: that psychological mindset please into stuff. It pleads into your behavior, 752 00:42:09,719 --> 00:42:13,120 Speaker 1: It plays into your belief systems, it pleads into high, 753 00:42:13,800 --> 00:42:16,800 Speaker 1: high effective that the treatment would be. I would imagine 754 00:42:17,080 --> 00:42:20,600 Speaker 1: through that belief idea. 755 00:42:20,280 --> 00:42:23,280 Speaker 2: Yeah, you should on this podcast I reckon your listeners 756 00:42:23,320 --> 00:42:27,640 Speaker 2: would like. Sean Zion is a researcher at Stanford and 757 00:42:27,719 --> 00:42:29,560 Speaker 2: he's done this stuff. He made this thing called the 758 00:42:29,600 --> 00:42:32,799 Speaker 2: Illness Mindset Inventory, and I think it was so this 759 00:42:32,880 --> 00:42:35,399 Speaker 2: is memory. Now I might be wrong, but I think 760 00:42:35,400 --> 00:42:38,359 Speaker 2: it was about cancer, and one of the items in 761 00:42:38,400 --> 00:42:41,360 Speaker 2: the questionnaire was about I see it as an opportunity. 762 00:42:42,640 --> 00:42:45,440 Speaker 2: It's just like, to me, that's just way too confronting. 763 00:42:45,560 --> 00:42:48,120 Speaker 2: It gives to a patient, right, and so, and he 764 00:42:48,160 --> 00:42:50,880 Speaker 2: could speak to all of that that research about like 765 00:42:51,239 --> 00:42:53,400 Speaker 2: when you say you see an injury as a challenge, 766 00:42:54,080 --> 00:42:56,560 Speaker 2: you see pain as an opportunity. Those kind of ideas 767 00:42:56,560 --> 00:42:59,840 Speaker 2: are just so hard to even grasp and it all 768 00:43:00,120 --> 00:43:03,279 Speaker 2: seems offensive to say it in the face of. 769 00:43:03,880 --> 00:43:07,719 Speaker 1: Well the historic philosophers believe that that that so their 770 00:43:07,800 --> 00:43:12,080 Speaker 1: whole attitude was that when you uncover misfortune, that that 771 00:43:12,239 --> 00:43:16,919 Speaker 1: this is a a good wrestling partner, that that will 772 00:43:16,960 --> 00:43:21,319 Speaker 1: actually enhanceure your strength and your resilience and your toughness. 773 00:43:21,440 --> 00:43:24,600 Speaker 1: So they actually saw these things are are reframed them 774 00:43:24,600 --> 00:43:29,439 Speaker 1: as opportunities and actually, in the extreme, welcomed them into 775 00:43:29,520 --> 00:43:33,279 Speaker 1: their lives. Right. So that's that that takes it to 776 00:43:33,600 --> 00:43:37,160 Speaker 1: another level. But if we did a little sidetrack there, 777 00:43:37,239 --> 00:43:41,320 Speaker 1: we just about got to the brain from the peripheral 778 00:43:41,320 --> 00:43:43,640 Speaker 1: nervous to the central nervous system and then up into 779 00:43:43,680 --> 00:43:47,759 Speaker 1: the brain. So what then, what's the next junction that 780 00:43:47,920 --> 00:43:49,480 Speaker 1: influences pain perception. 781 00:43:49,600 --> 00:43:53,200 Speaker 2: Yeah, so the way that there's some great work, like 782 00:43:53,239 --> 00:43:55,960 Speaker 2: there's a book called Explain Pain by David Butler and 783 00:43:56,080 --> 00:43:59,880 Speaker 2: Laura and Moseley. I like that. It's like a patient 784 00:44:00,080 --> 00:44:03,080 Speaker 2: friendly kind of way of explaining things. And the language 785 00:44:03,080 --> 00:44:06,200 Speaker 2: in that is pain is a distributed process, So there's 786 00:44:06,200 --> 00:44:09,360 Speaker 2: many different parts of the brain affecting the pain experience, 787 00:44:10,239 --> 00:44:12,680 Speaker 2: and this is a hard Like one of the challenges 788 00:44:13,440 --> 00:44:15,880 Speaker 2: with looking at this is like to say, you do 789 00:44:16,080 --> 00:44:20,600 Speaker 2: functional MRI like fMRI studies, and that's about blood flow changes, 790 00:44:20,640 --> 00:44:23,640 Speaker 2: and it's like, is that a perfect measure of what's 791 00:44:23,680 --> 00:44:28,560 Speaker 2: actually happening at a cellular level and physiological level. So 792 00:44:28,640 --> 00:44:31,560 Speaker 2: I think a lot of what I'm saying, I guess 793 00:44:31,640 --> 00:44:35,200 Speaker 2: will be clarified as science keeps getting better and our 794 00:44:35,200 --> 00:44:38,960 Speaker 2: ways of assessing and measuring stuff gets better. But yet, 795 00:44:39,040 --> 00:44:43,200 Speaker 2: just broadly speaking, I think what happens in the central 796 00:44:43,200 --> 00:44:46,120 Speaker 2: nervous system is just so multifactorial. Like that'd be the 797 00:44:46,120 --> 00:44:48,840 Speaker 2: take home message here is there's just so many different 798 00:44:48,880 --> 00:44:52,279 Speaker 2: little processes that are adding up. And if you want 799 00:44:52,320 --> 00:44:54,560 Speaker 2: to kind of experiment with this and develop your own 800 00:44:54,600 --> 00:44:58,040 Speaker 2: internal lock as control, start reflecting on different times you've 801 00:44:58,040 --> 00:45:00,000 Speaker 2: had the same pain, so it might be a headache 802 00:45:00,200 --> 00:45:03,400 Speaker 2: or whatever it is, sawne or something, and try and compare, 803 00:45:03,640 --> 00:45:05,880 Speaker 2: like what are all the ingredients if it was a 804 00:45:05,920 --> 00:45:09,320 Speaker 2: recipe in that pain versus pain A versus pain B, 805 00:45:09,960 --> 00:45:12,000 Speaker 2: And you can do this like in class. I've sat 806 00:45:12,040 --> 00:45:14,759 Speaker 2: in a lecture once where the lecturer got out us 807 00:45:14,760 --> 00:45:17,439 Speaker 2: to put our hands in a really icy cold cup 808 00:45:17,440 --> 00:45:21,600 Speaker 2: of water, and half the audience was looking at it 809 00:45:21,640 --> 00:45:23,480 Speaker 2: and it was told to stare at it, and the 810 00:45:23,520 --> 00:45:25,440 Speaker 2: other half of the audience was told to distract each 811 00:45:25,440 --> 00:45:27,799 Speaker 2: other and not think about it. And it was like 812 00:45:27,840 --> 00:45:30,600 Speaker 2: this really simple thing. It was one minute long, and 813 00:45:30,640 --> 00:45:33,080 Speaker 2: the pain ratings were so different, and it was really 814 00:45:33,120 --> 00:45:36,719 Speaker 2: fascinating Like that kind of like you can, like at 815 00:45:36,760 --> 00:45:40,279 Speaker 2: an acute, short term level, distraction and different strategies can 816 00:45:40,360 --> 00:45:43,480 Speaker 2: seem to help a little bit with the coping and 817 00:45:43,600 --> 00:45:46,960 Speaker 2: probably reduce the pain intensity itself. And so that's where 818 00:45:46,960 --> 00:45:50,719 Speaker 2: it's like, is the goal then to just like distract 819 00:45:50,800 --> 00:45:53,239 Speaker 2: our way out of long term pain? I don't know, 820 00:45:53,400 --> 00:45:55,480 Speaker 2: but maybe it can help us in those flare ups, 821 00:45:55,480 --> 00:46:00,200 Speaker 2: those times where pain seems insurmountable. There are strategies I 822 00:46:00,200 --> 00:46:03,239 Speaker 2: guess so coming up with a plan for long term 823 00:46:03,239 --> 00:46:05,720 Speaker 2: improvement is good, but also coming up with a plan 824 00:46:05,840 --> 00:46:09,160 Speaker 2: for short term coping, I think is really helpful. And 825 00:46:09,200 --> 00:46:11,200 Speaker 2: you want to weigh up the benefits and risks of 826 00:46:11,239 --> 00:46:13,520 Speaker 2: all of the different strategies you're using. And if you 827 00:46:13,520 --> 00:46:16,560 Speaker 2: think you're not using any strategies, you are. You're probably 828 00:46:16,640 --> 00:46:20,359 Speaker 2: just resting and taking medications, and those are passive, like 829 00:46:20,400 --> 00:46:22,879 Speaker 2: they feel like not even a choice, but you are 830 00:46:22,960 --> 00:46:25,280 Speaker 2: actually choosing to do those things. And if you start 831 00:46:25,520 --> 00:46:29,960 Speaker 2: putting the internal lookers of control inside you, then you 832 00:46:30,000 --> 00:46:31,719 Speaker 2: start going, oh, I do have a choice here, and 833 00:46:31,760 --> 00:46:34,520 Speaker 2: if I choose to do that again, that might have 834 00:46:34,600 --> 00:46:37,279 Speaker 2: this consequence. And if I choose to do that, then 835 00:46:37,320 --> 00:46:39,960 Speaker 2: that might have this consequence. And that's when you see 836 00:46:39,960 --> 00:46:42,520 Speaker 2: people start going, oh, I go to the gym, but 837 00:46:42,600 --> 00:46:45,200 Speaker 2: I think it's about the social benefits that's really helping 838 00:46:45,239 --> 00:46:48,560 Speaker 2: me or whatever, And you go, yeah, pain is it's biological, 839 00:46:48,600 --> 00:46:52,360 Speaker 2: it's psychological, and it's social all the time, every single time. 840 00:46:53,440 --> 00:46:56,000 Speaker 2: And I think embracing that is just where we start 841 00:46:56,040 --> 00:46:58,880 Speaker 2: to see this shift, and that's where I'm optimistic about 842 00:46:58,880 --> 00:47:01,400 Speaker 2: the future of pain related healthcare. 843 00:47:01,920 --> 00:47:05,520 Speaker 1: Can I give you a very concrete example. So I'm 844 00:47:05,560 --> 00:47:08,319 Speaker 1: going to be your physiotherapy student and bring this. Let's 845 00:47:08,320 --> 00:47:12,520 Speaker 1: do it to my experience. Right. So by eighteen months 846 00:47:12,520 --> 00:47:17,080 Speaker 1: two years ago, there was a little issue with some 847 00:47:17,200 --> 00:47:21,440 Speaker 1: of my blood work were the white blood cell kind 848 00:47:21,640 --> 00:47:25,040 Speaker 1: was pretty low, and they did some investigations and stuff 849 00:47:25,080 --> 00:47:28,640 Speaker 1: like that, and went to see a specialist and they went, oh, 850 00:47:28,920 --> 00:47:31,120 Speaker 1: I think you're okay, did some further blow brock, and 851 00:47:31,160 --> 00:47:34,000 Speaker 1: then it was again, And then I suppose to Doug said, 852 00:47:34,000 --> 00:47:36,239 Speaker 1: on are my options here? And I said, well, the 853 00:47:36,320 --> 00:47:42,440 Speaker 1: obvious thing that they're worried about with that is obviously cancer, right, 854 00:47:42,520 --> 00:47:45,160 Speaker 1: and a particular type of cancer. So we said, the 855 00:47:45,200 --> 00:47:48,040 Speaker 1: way that you can just know for sure is going 856 00:47:48,080 --> 00:47:51,400 Speaker 1: get a lumber puncture, right, and get a what do 857 00:47:51,440 --> 00:47:53,160 Speaker 1: you call it? Would they take a little bit of 858 00:47:53,200 --> 00:47:57,080 Speaker 1: the bone marrow, right, So get a bone marrow puncture 859 00:47:57,280 --> 00:47:59,960 Speaker 1: and analyze that. So I said, right, let's do it. 860 00:48:00,080 --> 00:48:04,239 Speaker 1: So I went in to get it, and I got 861 00:48:04,320 --> 00:48:10,239 Speaker 1: it the day after my book Death by Comfort was published. Right, 862 00:48:10,560 --> 00:48:14,400 Speaker 1: So here's the context. So I go in and they 863 00:48:14,520 --> 00:48:17,880 Speaker 1: come around and they give you a little local anesthetic 864 00:48:17,920 --> 00:48:20,600 Speaker 1: and then the nurse says, right, the doctor's going to 865 00:48:20,600 --> 00:48:23,359 Speaker 1: be around in a minute to give you morphine, and 866 00:48:23,480 --> 00:48:27,000 Speaker 1: once the morphine kicks in, then we'll do the lumber puncture. 867 00:48:27,480 --> 00:48:30,800 Speaker 1: And I said, what's the morphine for and she said, well, 868 00:48:31,000 --> 00:48:35,520 Speaker 1: it's a very uncomfortable experience. The morphine is just to 869 00:48:35,680 --> 00:48:38,600 Speaker 1: increase your comfort level. And I looked at her and 870 00:48:38,600 --> 00:48:41,799 Speaker 1: I went, I can't have it. I've just published a 871 00:48:41,800 --> 00:48:44,719 Speaker 1: book called Death by Comfort, Why modern life is killing 872 00:48:44,800 --> 00:48:46,759 Speaker 1: us and what we need to do about it. You're 873 00:48:46,800 --> 00:48:49,319 Speaker 1: telling me this is to make me more comfortable. I 874 00:48:49,360 --> 00:48:52,120 Speaker 1: don't want the morphine. And she went, are you crazy 875 00:48:52,120 --> 00:48:55,360 Speaker 1: in the head? And she found this fascinating. So we 876 00:48:55,400 --> 00:48:57,279 Speaker 1: had a chat about it, and then she brought the 877 00:48:57,320 --> 00:49:01,400 Speaker 1: doctor over and I went, I don't want to just 878 00:49:01,640 --> 00:49:04,520 Speaker 1: crack on and he said, and he says, well, everybody 879 00:49:04,560 --> 00:49:08,200 Speaker 1: takes the morphing, he says, apart from people who have 880 00:49:08,719 --> 00:49:12,640 Speaker 1: a reaction to morphine analogy. Yeah. And I said, well 881 00:49:12,640 --> 00:49:15,520 Speaker 1: do they die and he said no. I said, well 882 00:49:15,719 --> 00:49:19,160 Speaker 1: crack on. And so they thought this was very interesting. 883 00:49:19,200 --> 00:49:23,440 Speaker 1: But the nurse then as it was happening, she grabbed 884 00:49:23,440 --> 00:49:26,800 Speaker 1: my hand and started talking to me, and he started 885 00:49:26,800 --> 00:49:29,600 Speaker 1: having a little bit of a laugh around stuff and 886 00:49:30,640 --> 00:49:34,360 Speaker 1: I think two things played in to make that manageable. 887 00:49:34,920 --> 00:49:38,560 Speaker 1: One was my internal locus of control and the fact 888 00:49:38,560 --> 00:49:40,640 Speaker 1: that I just published a book called Death by Comfort 889 00:49:40,680 --> 00:49:44,359 Speaker 1: and this was a boat identity, right, So I think 890 00:49:44,520 --> 00:49:49,520 Speaker 1: that gave me a certain level of control or intended control, 891 00:49:49,560 --> 00:49:52,319 Speaker 1: if you like, over the pain. And then the fact 892 00:49:52,360 --> 00:49:55,920 Speaker 1: that the nurse who thought this was so fascinating, he 893 00:49:56,080 --> 00:49:58,520 Speaker 1: was grabbing my hand and just trying to distract me 894 00:49:58,560 --> 00:50:00,640 Speaker 1: and ask about questions and we having a bit of 895 00:50:00,640 --> 00:50:05,359 Speaker 1: a laugh Wiley fucking because it's pretty horrible alonger for puncture, right, 896 00:50:06,520 --> 00:50:11,520 Speaker 1: But that for me just plays into that whole internal 897 00:50:11,560 --> 00:50:14,680 Speaker 1: looks of control and the distraction element of things. 898 00:50:14,760 --> 00:50:18,720 Speaker 2: Yeah, yeah, yeah, there was a really interesting study looking 899 00:50:18,719 --> 00:50:21,399 Speaker 2: at I think it was epidurals and the language that's 900 00:50:21,520 --> 00:50:24,799 Speaker 2: used when the doctor's about to come in and if 901 00:50:24,840 --> 00:50:27,399 Speaker 2: it gets compared to yeah, this is the worst part 902 00:50:27,400 --> 00:50:31,239 Speaker 2: of the procedure versus sorry, it's like a beasting, and 903 00:50:31,239 --> 00:50:37,239 Speaker 2: it's the worst part of the procedure versus something like oh, 904 00:50:37,360 --> 00:50:39,600 Speaker 2: I can't of remember, this is uncomfortable or a little 905 00:50:39,600 --> 00:50:41,799 Speaker 2: bit of pressure or something like that, and they just 906 00:50:42,200 --> 00:50:44,239 Speaker 2: changed I think it was seven different words in the 907 00:50:44,320 --> 00:50:48,200 Speaker 2: sentence in the two groups of women, and in this 908 00:50:48,280 --> 00:50:50,759 Speaker 2: study the pain difference was more than two out of 909 00:50:50,760 --> 00:50:55,919 Speaker 2: ten on average, just from the language change and your Yeah, 910 00:50:55,960 --> 00:50:59,239 Speaker 2: in your example, you identified that it was an identity 911 00:50:59,280 --> 00:51:01,520 Speaker 2: thing for you. It was good timing in terms of 912 00:51:01,560 --> 00:51:04,759 Speaker 2: the book. You had really good rapport with the nurse. 913 00:51:04,800 --> 00:51:06,480 Speaker 2: By the sound of it. It was fun and it was 914 00:51:06,520 --> 00:51:09,440 Speaker 2: a bit silly, and you're kind of like almost mocking 915 00:51:09,480 --> 00:51:11,200 Speaker 2: the facts of what's going on and all that. So 916 00:51:11,360 --> 00:51:14,080 Speaker 2: like it's just like a really, that's a hard thing 917 00:51:14,160 --> 00:51:16,040 Speaker 2: to replicate in anyone else, because no one else has 918 00:51:16,040 --> 00:51:20,000 Speaker 2: published that book the day before, right, and just seeing 919 00:51:20,080 --> 00:51:24,920 Speaker 2: these the fact that the nurse grasped onto distraction and 920 00:51:25,000 --> 00:51:29,560 Speaker 2: handholding and comfort and laughing and so like, you've got 921 00:51:29,560 --> 00:51:35,480 Speaker 2: this nice biapsychosocial coping strategy, and our body has internal 922 00:51:36,000 --> 00:51:40,560 Speaker 2: like they're called endogenous opioids, and so like your internal 923 00:51:40,600 --> 00:51:42,920 Speaker 2: system would have been doing its best. 924 00:51:43,239 --> 00:51:47,240 Speaker 1: No, and I suspect, you know, this is a complete 925 00:51:47,280 --> 00:51:50,400 Speaker 1: guess that it probably up regulated more than if I 926 00:51:50,440 --> 00:51:51,360 Speaker 1: got the morphine. 927 00:51:51,680 --> 00:51:54,480 Speaker 2: I would guess, oh, yes, yes, yes, So yeah, we 928 00:51:54,480 --> 00:51:57,960 Speaker 2: see this in people who take opioids long term, their 929 00:51:58,239 --> 00:52:01,560 Speaker 2: ability to generate the internal opioids. I think it seems 930 00:52:01,560 --> 00:52:04,920 Speaker 2: like it's reduced. And so there's this conditioned kind of 931 00:52:05,000 --> 00:52:09,080 Speaker 2: state that happens where it's called opioid induced hyper algaesier, 932 00:52:09,160 --> 00:52:11,400 Speaker 2: where you take the tablet and it makes the pain worse. 933 00:52:12,600 --> 00:52:15,160 Speaker 2: And that's a really hard thing when people are dependent 934 00:52:15,200 --> 00:52:17,279 Speaker 2: on it. They can't stop taking it, but it's making 935 00:52:17,280 --> 00:52:18,680 Speaker 2: it worse. And they can't stop taking it, but it's 936 00:52:18,719 --> 00:52:20,840 Speaker 2: made it worse. And that's some of the kind of 937 00:52:20,880 --> 00:52:25,520 Speaker 2: the challenges that we see with these these external things 938 00:52:25,600 --> 00:52:30,800 Speaker 2: like surgeries, needles, medications, and that's why internal strategies are promoted. 939 00:52:30,840 --> 00:52:33,919 Speaker 2: But I don't want people to go, oh, well, Paul 940 00:52:34,000 --> 00:52:36,560 Speaker 2: did it. I'm going to do the same thing necessarily, 941 00:52:36,600 --> 00:52:38,680 Speaker 2: I think informed decision. 942 00:52:39,040 --> 00:52:42,200 Speaker 1: I'm a bit of a nutter, right, they don't try this, 943 00:52:42,800 --> 00:52:45,279 Speaker 1: but it would have been a really interesting experiment, right 944 00:52:45,360 --> 00:52:49,239 Speaker 1: to do the lumber puncture with just me and the 945 00:52:49,239 --> 00:52:52,640 Speaker 1: boat and nan have another one where it's the gnose 946 00:52:53,239 --> 00:52:57,520 Speaker 1: right and and there, and do the comparison, and that'd 947 00:52:57,560 --> 00:53:02,040 Speaker 1: be an interesting controlled experiment to see what elements played 948 00:53:02,080 --> 00:53:04,680 Speaker 1: into it, whether I just published the book or not 949 00:53:04,680 --> 00:53:06,719 Speaker 1: published the book, and whether the nose was holding my 950 00:53:06,760 --> 00:53:09,080 Speaker 1: hand had distracted me or not distract me, but anyway, 951 00:53:09,760 --> 00:53:10,200 Speaker 1: one of the. 952 00:53:10,160 --> 00:53:13,080 Speaker 2: Things with that is it's really hard just to be 953 00:53:13,120 --> 00:53:16,439 Speaker 2: able to have the control group right, Like, you can't Yeah, 954 00:53:16,480 --> 00:53:19,440 Speaker 2: you can't do that very well. And there's a researcher 955 00:53:19,480 --> 00:53:21,359 Speaker 2: I work with. His name's Mick Thacker, who does all 956 00:53:21,360 --> 00:53:23,960 Speaker 2: this stuff on predictive processing, and they're doing work in AI, 957 00:53:24,520 --> 00:53:27,480 Speaker 2: and the long term goal is a digital twin so 958 00:53:27,520 --> 00:53:29,880 Speaker 2: you can FEEDO type get a similar like it's like 959 00:53:29,920 --> 00:53:33,000 Speaker 2: a virtual Paul, and they could test stuff and see 960 00:53:33,000 --> 00:53:34,919 Speaker 2: how your body would react, and then they could test 961 00:53:34,920 --> 00:53:38,840 Speaker 2: another condition. And so I think potentially technology might allow 962 00:53:38,960 --> 00:53:42,279 Speaker 2: us to start answering these questions of like, oh, if 963 00:53:42,280 --> 00:53:44,360 Speaker 2: we could have a control group, we'd be able to 964 00:53:44,360 --> 00:53:47,239 Speaker 2: find out if it why Yeah. And I think once 965 00:53:47,280 --> 00:53:50,520 Speaker 2: we get to that point, we'll have so many more 966 00:53:50,600 --> 00:53:53,360 Speaker 2: answers than questions. Whereas at the moment, I feel like 967 00:53:53,400 --> 00:53:56,200 Speaker 2: every study I do, like I think we're up to 968 00:53:56,280 --> 00:53:59,000 Speaker 2: like eight papers this year, and it's like every single paper, 969 00:53:59,040 --> 00:54:01,240 Speaker 2: I'm like, we've just ended up with more questions questions. 970 00:54:01,680 --> 00:54:03,239 Speaker 2: It's like we've chipped away at it and it's a 971 00:54:03,239 --> 00:54:06,680 Speaker 2: better question than ever before, and we've answered something, but 972 00:54:06,760 --> 00:54:10,000 Speaker 2: like now there's even more things to answer and that's 973 00:54:10,080 --> 00:54:12,320 Speaker 2: just I guess it's part of the excitement of research 974 00:54:12,440 --> 00:54:15,200 Speaker 2: is you're having discussions and you're thinking about things that 975 00:54:15,280 --> 00:54:17,359 Speaker 2: no one has thought about in the past because we've 976 00:54:17,360 --> 00:54:20,160 Speaker 2: never known what we've known now. And I love that. Like, 977 00:54:20,239 --> 00:54:22,440 Speaker 2: to me, that's just like in twenty years or thirty 978 00:54:22,480 --> 00:54:24,920 Speaker 2: forty years, I'm definitely going to have that feeling still 979 00:54:25,160 --> 00:54:26,240 Speaker 2: and it's really exciting. 980 00:54:26,320 --> 00:54:28,759 Speaker 1: Yeah, it's the never ending quest for knowledge, right, It's 981 00:54:29,400 --> 00:54:32,239 Speaker 1: the gift that keeps on giving. Let's I am a 982 00:54:32,280 --> 00:54:33,960 Speaker 1: little bit of ware of time, and I do want 983 00:54:33,960 --> 00:54:37,840 Speaker 1: to talk about the children's stuff, right, So you have 984 00:54:37,920 --> 00:54:43,040 Speaker 1: written some books on and little bits of videos for children. 985 00:54:43,400 --> 00:54:48,000 Speaker 1: What to talk to me about the challenge of translating 986 00:54:49,280 --> 00:54:53,080 Speaker 1: all of the complex stuff you know to kids and 987 00:54:53,480 --> 00:54:55,840 Speaker 1: what if you find that actually works. 988 00:54:56,080 --> 00:54:58,640 Speaker 2: I've got them actually they're just sitting here. So the 989 00:54:58,719 --> 00:55:02,759 Speaker 2: kids books, it's a series five independent books and then 990 00:55:02,760 --> 00:55:03,879 Speaker 2: you can get them in a set as well. 991 00:55:03,920 --> 00:55:05,560 Speaker 1: Zoe and Zach's panhakes. 992 00:55:05,560 --> 00:55:08,160 Speaker 2: I love it, yes, yeah, yeah. And the idea is 993 00:55:08,200 --> 00:55:10,759 Speaker 2: that rather than having a resource that covers lots of 994 00:55:10,760 --> 00:55:13,000 Speaker 2: different topics, like kind of like in this podcast, we've 995 00:55:13,000 --> 00:55:15,080 Speaker 2: covered so many different topics and there's all these differ 996 00:55:15,160 --> 00:55:19,000 Speaker 2: rabbit holes that people can go down. I think for kids, like, 997 00:55:19,200 --> 00:55:22,480 Speaker 2: how can we work out if all of these messages 998 00:55:22,520 --> 00:55:24,840 Speaker 2: are helpful or maybe some of these messages are helpful. 999 00:55:25,160 --> 00:55:27,040 Speaker 2: What I wanted to do is like, let's break them 1000 00:55:27,080 --> 00:55:31,080 Speaker 2: into discrete resources and we can see, Oh, the kids 1001 00:55:31,080 --> 00:55:33,880 Speaker 2: who have chronic pains seem to benefit most from the 1002 00:55:33,960 --> 00:55:36,720 Speaker 2: third book, and then or if they want to engage 1003 00:55:36,719 --> 00:55:39,319 Speaker 2: in exercise and greater exposure, the fourth book's a good 1004 00:55:39,320 --> 00:55:42,520 Speaker 2: starting point, and we're finding out some stuff about the 1005 00:55:42,600 --> 00:55:46,360 Speaker 2: nitty gritty of the education. Whereas I think because like 1006 00:55:46,440 --> 00:55:48,880 Speaker 2: for some people, if you say, oh, pain doesn't relate 1007 00:55:48,920 --> 00:55:52,759 Speaker 2: to damage very well, even in a lab setting, some 1008 00:55:52,800 --> 00:55:55,840 Speaker 2: people get so upset with that message because it's just 1009 00:55:55,880 --> 00:55:57,799 Speaker 2: like you're saying, Hey, are you saying I'm faking it? 1010 00:55:58,040 --> 00:55:58,279 Speaker 1: Yeah? 1011 00:55:58,520 --> 00:56:01,319 Speaker 2: Whereas for other people it's so oh, it's such an 1012 00:56:01,360 --> 00:56:04,560 Speaker 2: important part of their journey, having that moment where they 1013 00:56:04,680 --> 00:56:08,479 Speaker 2: learned that. Whereas I think everyone like the second book 1014 00:56:08,560 --> 00:56:10,640 Speaker 2: in this series I can show you. I don't know 1015 00:56:10,680 --> 00:56:13,360 Speaker 2: if people will be able to watch this but yeah. 1016 00:56:13,360 --> 00:56:15,080 Speaker 2: This is called Zoe z Oppen's Lights It Up, and 1017 00:56:15,320 --> 00:56:18,120 Speaker 2: it's based on a real lab study where in the 1018 00:56:18,120 --> 00:56:21,600 Speaker 2: presence of a different colored light people felt different amounts 1019 00:56:21,600 --> 00:56:24,240 Speaker 2: of pain. And so in the story, little Zoe visits 1020 00:56:24,239 --> 00:56:27,200 Speaker 2: her grandma's lab and there's the red light and the 1021 00:56:27,200 --> 00:56:29,839 Speaker 2: blue light. And I'm sure I reckon you could guess 1022 00:56:29,840 --> 00:56:32,719 Speaker 2: this correctly. People felt more pain in the presence of 1023 00:56:32,760 --> 00:56:33,320 Speaker 2: which color. 1024 00:56:33,760 --> 00:56:38,240 Speaker 1: I would say, Oh, interesting, blue light, I would say 1025 00:56:38,680 --> 00:56:39,920 Speaker 1: more blue. 1026 00:56:41,360 --> 00:56:43,680 Speaker 2: So pain, more pain with blue or more pain with red? 1027 00:56:43,719 --> 00:56:47,080 Speaker 1: What do you think I would Oh, No, more pain 1028 00:56:47,120 --> 00:56:49,640 Speaker 1: with red, for sure, more pain with red because red 1029 00:56:50,000 --> 00:56:52,160 Speaker 1: would be associated with pain and inflammation. 1030 00:56:52,840 --> 00:56:56,080 Speaker 2: Yeah, sure, and stop signs and danger and warning and. 1031 00:56:56,360 --> 00:56:59,759 Speaker 1: All of that interesting little aside. Right, So placeboll in 1032 00:57:00,080 --> 00:57:07,520 Speaker 1: resting that blue pills are better for anxiety, right, unless 1033 00:57:07,560 --> 00:57:12,520 Speaker 1: you're an Italian meal and which kiss they're not because 1034 00:57:12,600 --> 00:57:15,960 Speaker 1: they get excited about blue because that's the color of 1035 00:57:16,000 --> 00:57:17,840 Speaker 1: the national soccer teams soccer team. 1036 00:57:17,920 --> 00:57:22,880 Speaker 2: Yeah right, yes, so it's really fac so I think yes. Anyway, 1037 00:57:22,880 --> 00:57:26,680 Speaker 2: we basically this kid's book is about I'm kind of 1038 00:57:26,680 --> 00:57:30,480 Speaker 2: helping kids grasp the study more or less and go 1039 00:57:30,600 --> 00:57:32,600 Speaker 2: hang on like The key line in the book is 1040 00:57:32,600 --> 00:57:34,600 Speaker 2: if a little light can change the volume of pain, 1041 00:57:34,920 --> 00:57:37,360 Speaker 2: plenty more is possible in my brainy brain. And then 1042 00:57:37,360 --> 00:57:40,080 Speaker 2: it goes through the BIA psychosocial model and it's all 1043 00:57:40,080 --> 00:57:43,360 Speaker 2: written like a kind of Doctor Susian style, lots of 1044 00:57:43,440 --> 00:57:46,600 Speaker 2: fun and cartoons, interactive way of thinking about it. And 1045 00:57:46,640 --> 00:57:50,439 Speaker 2: for me, I don't think it's like the books. I mean, 1046 00:57:50,560 --> 00:57:53,400 Speaker 2: I get emails from people saying the books have changed 1047 00:57:53,440 --> 00:57:55,840 Speaker 2: my kid's life, it's fixed our whole family, and it's 1048 00:57:55,840 --> 00:57:57,480 Speaker 2: like as if it's a cure, and I'm like, I 1049 00:57:57,520 --> 00:58:01,600 Speaker 2: don't think that's really like a good way of thinking 1050 00:58:01,640 --> 00:58:04,360 Speaker 2: about the books necessarily, like often they can be a support, 1051 00:58:05,000 --> 00:58:07,000 Speaker 2: but for me, I think at a minimum they're a 1052 00:58:07,000 --> 00:58:09,920 Speaker 2: conversation starter. And so a lot of clinics and stuff 1053 00:58:09,960 --> 00:58:13,240 Speaker 2: have this open and they've got the kid with juvenile 1054 00:58:13,600 --> 00:58:17,960 Speaker 2: arthritis and they're going the rheumatologists are saying, well, the 1055 00:58:18,000 --> 00:58:21,080 Speaker 2: disease is at bay at the moment, it's okay, and 1056 00:58:21,120 --> 00:58:23,200 Speaker 2: then the family's left going, well, why do I have 1057 00:58:23,240 --> 00:58:26,120 Speaker 2: all this pain? And so the books are kind of 1058 00:58:26,160 --> 00:58:30,720 Speaker 2: functioning as that conversation starter piece of going The science 1059 00:58:30,760 --> 00:58:33,439 Speaker 2: doesn't need to be that inaccessible and complex, like, let's 1060 00:58:33,440 --> 00:58:36,000 Speaker 2: bring it down and what do you think of Zoe's experience? 1061 00:58:36,000 --> 00:58:38,480 Speaker 2: And I think having a character and a relatable way 1062 00:58:38,800 --> 00:58:43,000 Speaker 2: of approaching the topic is much better than a textbook. 1063 00:58:43,600 --> 00:58:47,040 Speaker 2: But obviously I'm biased. I've made the resource. But yeah, 1064 00:58:47,080 --> 00:58:49,400 Speaker 2: so that's kind of the backstory of the books. And 1065 00:58:49,520 --> 00:58:52,440 Speaker 2: it's been so cool to see, like you write a 1066 00:58:52,480 --> 00:58:54,480 Speaker 2: research paper and a few thousand people see it in 1067 00:58:54,520 --> 00:58:56,880 Speaker 2: a year or something, but you do something like a 1068 00:58:56,880 --> 00:58:59,040 Speaker 2: ted ed video or you make kids books and it 1069 00:58:59,240 --> 00:59:02,040 Speaker 2: just goes out to so many more people, and I 1070 00:59:02,160 --> 00:59:05,120 Speaker 2: just I love that, Like I think, yeah, the reason 1071 00:59:05,160 --> 00:59:07,760 Speaker 2: I moved from clinical work into to research and to 1072 00:59:07,880 --> 00:59:10,240 Speaker 2: teaching is to try and help more than one person 1073 00:59:10,240 --> 00:59:12,440 Speaker 2: at a time. It's like a good version of a 1074 00:59:12,480 --> 00:59:16,640 Speaker 2: pyramid scheme kind of thing. Yeah, but it's like we 1075 00:59:16,680 --> 00:59:20,120 Speaker 2: can using mass media and the Internet. It's facilitated the 1076 00:59:20,200 --> 00:59:24,040 Speaker 2: chance to disseminate knowledge at a greater rate to more 1077 00:59:24,120 --> 00:59:26,640 Speaker 2: and more people and to kind of even out some 1078 00:59:26,680 --> 00:59:30,160 Speaker 2: of these health literacy inequalities around the world. And so 1079 00:59:30,200 --> 00:59:32,120 Speaker 2: I want to contribute to those efforts, and I think 1080 00:59:32,520 --> 00:59:34,200 Speaker 2: hopefully there's people wanting to do the same. 1081 00:59:34,680 --> 00:59:36,720 Speaker 1: Have you turned the book. I thought about turning the 1082 00:59:36,720 --> 00:59:41,520 Speaker 1: book into a series of little TikTok videos and yeah, 1083 00:59:41,560 --> 00:59:44,480 Speaker 1: an animeate it, right, because that would go out and 1084 00:59:44,480 --> 00:59:45,800 Speaker 1: read so many kids. 1085 00:59:46,360 --> 00:59:49,280 Speaker 2: Yes, yes, so there's been talks about like a TV thing. 1086 00:59:49,880 --> 00:59:52,240 Speaker 2: There's lots of these kind of it's all in early 1087 00:59:52,280 --> 00:59:53,920 Speaker 2: stages and we haven't done it yet. So if someone's 1088 00:59:53,960 --> 00:59:58,680 Speaker 2: listening and so, they should reach out later. But it's 1089 00:59:58,720 --> 01:00:02,640 Speaker 2: a hard thing going, Yeah, just what's that next step? Like, 1090 01:00:02,680 --> 01:00:05,280 Speaker 2: how do we help people more than what we're currently doing? 1091 01:00:05,360 --> 01:00:07,840 Speaker 2: And I think that's my job as a researcher, is 1092 01:00:07,880 --> 01:00:09,959 Speaker 2: to try and be strategic and think in the long 1093 01:00:10,040 --> 01:00:13,840 Speaker 2: term about these strategies. But yeah, I just can't believe 1094 01:00:13,920 --> 01:00:18,959 Speaker 2: how helpful a shiny resource is versus like a photocopied 1095 01:00:19,040 --> 01:00:22,720 Speaker 2: stick figure drawing. It seems to have a real big 1096 01:00:22,720 --> 01:00:26,200 Speaker 2: effect on our current kind of Western culture and approach 1097 01:00:26,240 --> 01:00:31,200 Speaker 2: to how we consume information. It's really hard, I think. Yeah, 1098 01:00:31,240 --> 01:00:33,360 Speaker 2: as you mentioned, like things like TikTok are just changing 1099 01:00:33,360 --> 01:00:36,760 Speaker 2: the way that people kind of process their learning. 1100 01:00:37,560 --> 01:00:41,600 Speaker 1: So me, you clearly have a very infectious enthusiasm for 1101 01:00:42,400 --> 01:00:46,720 Speaker 1: what you do. What are you excited about on the horizon. 1102 01:00:47,080 --> 01:00:50,560 Speaker 2: Yeah, I've actually just worked on another kids book series 1103 01:00:50,600 --> 01:00:53,040 Speaker 2: for preschoolers. So like, I guess it's this question of 1104 01:00:53,080 --> 01:00:54,880 Speaker 2: how young do we go right, Like do we go 1105 01:00:54,960 --> 01:00:58,240 Speaker 2: back all the way to like the breastfeeding mom or 1106 01:00:58,240 --> 01:01:00,760 Speaker 2: maybe in utero the expecting pair. Who do we want 1107 01:01:00,800 --> 01:01:03,840 Speaker 2: to educate? And I think so the step from primary 1108 01:01:03,880 --> 01:01:06,320 Speaker 2: school is to go to preschool. And you can't talk 1109 01:01:06,320 --> 01:01:08,520 Speaker 2: about pain. I don't think it, Like, I mean you could, 1110 01:01:08,600 --> 01:01:12,520 Speaker 2: and you could talk about acute pain management strategies, but 1111 01:01:12,600 --> 01:01:15,280 Speaker 2: I think what's good for the nervous system in the 1112 01:01:15,320 --> 01:01:17,240 Speaker 2: long term, Like they're the kinds of things I want 1113 01:01:17,280 --> 01:01:19,840 Speaker 2: to be educating and providing the science about. And so 1114 01:01:19,920 --> 01:01:23,160 Speaker 2: we've made this book for preschoolers, and it's about physical 1115 01:01:23,160 --> 01:01:26,720 Speaker 2: activity and play based activity. And it's not like I'll 1116 01:01:26,720 --> 01:01:29,120 Speaker 2: do three sets of ten of this exercise or anything 1117 01:01:29,160 --> 01:01:33,240 Speaker 2: like that. It's like, let's just kind of normalize outdoor 1118 01:01:33,680 --> 01:01:37,720 Speaker 2: fun adventures, play using our gross motor fine motor skills, 1119 01:01:38,240 --> 01:01:41,480 Speaker 2: like kind of helping people readiness for school, and like 1120 01:01:41,600 --> 01:01:45,840 Speaker 2: thinking just more whole child than three one body part. 1121 01:01:45,800 --> 01:01:49,200 Speaker 1: Free range children rather than pregging buttery children. 1122 01:01:50,560 --> 01:01:51,800 Speaker 2: That's what funny, Like I. 1123 01:01:51,720 --> 01:01:53,920 Speaker 1: Don't need seriously that's what we need to get back to, 1124 01:01:54,120 --> 01:01:58,600 Speaker 1: is rearsing free range kids, whether ranging and climbing trees 1125 01:01:58,640 --> 01:02:02,280 Speaker 1: and doing shit and learning stuff, rather than battery kids 1126 01:02:02,280 --> 01:02:04,360 Speaker 1: that are stuck inside on screens. Yeah. 1127 01:02:04,440 --> 01:02:07,480 Speaker 2: Yeah, and it's funny. I'm not, like, I'm a physio 1128 01:02:07,560 --> 01:02:10,560 Speaker 2: and obviously biased towards doing more exercise and stuff, but 1129 01:02:10,800 --> 01:02:14,320 Speaker 2: I think screens and some of the technological advancements for 1130 01:02:14,360 --> 01:02:16,440 Speaker 2: people to be able to learn more efficiently is just 1131 01:02:16,520 --> 01:02:19,560 Speaker 2: like mind blowing. And so I'm not against screens, but 1132 01:02:19,600 --> 01:02:22,800 Speaker 2: I think there's just the childhood that a lot of 1133 01:02:22,840 --> 01:02:26,720 Speaker 2: adults grew up with is not the same now, and 1134 01:02:27,560 --> 01:02:30,200 Speaker 2: there's this real thirst for like how do we marry 1135 01:02:30,240 --> 01:02:33,000 Speaker 2: this up of like, Okay, screens are kind of unavoidable, 1136 01:02:33,520 --> 01:02:36,160 Speaker 2: so we need to make it clear that there's benefits 1137 01:02:36,160 --> 01:02:40,680 Speaker 2: of also doing other stuff. And so it's raising that conversation. 1138 01:02:40,800 --> 01:02:43,600 Speaker 2: Is this next step, And I guess the to answer 1139 01:02:43,600 --> 01:02:46,240 Speaker 2: your question about the excitement, it's about thinking like, can 1140 01:02:46,280 --> 01:02:50,200 Speaker 2: we make a kind of curriculum or a big societal 1141 01:02:50,320 --> 01:02:53,400 Speaker 2: change for every age group across the whole lifespan. That's 1142 01:02:53,400 --> 01:02:54,760 Speaker 2: where I'm heading at the moment. 1143 01:02:55,120 --> 01:02:58,720 Speaker 1: Yeah, very cool, Josh. This has been bloody interesting. Who 1144 01:02:58,760 --> 01:03:01,200 Speaker 1: would know that a com about pain could be so 1145 01:03:01,280 --> 01:03:01,760 Speaker 1: much fun. 1146 01:03:03,000 --> 01:03:05,560 Speaker 2: I'm so glad. I really enjoyed it, and I appreciate 1147 01:03:05,920 --> 01:03:08,840 Speaker 2: you clearly have so much knowledge about such a big, 1148 01:03:08,920 --> 01:03:11,920 Speaker 2: broad number of topics. I kind of feel like I'm 1149 01:03:11,960 --> 01:03:16,240 Speaker 2: so narrowly focused and got my blinders on looking at pain. 1150 01:03:16,320 --> 01:03:19,800 Speaker 1: But yeah, well I'm a whatether they call it a 1151 01:03:21,480 --> 01:03:24,800 Speaker 1: it's the master of none, a jack of ultra, jack 1152 01:03:24,840 --> 01:03:27,479 Speaker 1: of all tree, it's a master of none. But yeah, 1153 01:03:27,720 --> 01:03:32,000 Speaker 1: look for me, I think I sure your enthusiasm just 1154 01:03:32,200 --> 01:03:36,760 Speaker 1: for or like awe about the body in general, and 1155 01:03:37,000 --> 01:03:41,400 Speaker 1: just high freaking cool shit is when you look onto 1156 01:03:41,440 --> 01:03:45,120 Speaker 1: the hoot, at the nervous system, the muscle system, you know, 1157 01:03:45,160 --> 01:03:48,080 Speaker 1: all of our systems and just how they react to 1158 01:03:48,320 --> 01:03:52,080 Speaker 1: inputs from the environment and psychology and all of that 1159 01:03:52,120 --> 01:03:55,720 Speaker 1: stuff is just so boddy fascinating. It's very cool. 1160 01:03:56,160 --> 01:03:56,960 Speaker 2: Totally agree. 1161 01:03:57,200 --> 01:04:01,720 Speaker 1: So keep doing what you're doing, keep your factious enthusiasm, 1162 01:04:02,320 --> 01:04:04,440 Speaker 1: because I think that that has a big impact. And 1163 01:04:05,800 --> 01:04:07,880 Speaker 1: it would be very cool to be a student of 1164 01:04:07,920 --> 01:04:10,919 Speaker 1: yours getting lectured too, rather than these boring as butt 1165 01:04:10,960 --> 01:04:13,640 Speaker 1: shit lecturers that are tan. 1166 01:04:16,640 --> 01:04:18,880 Speaker 2: Yeah, I hope there's little bits and pieces that are 1167 01:04:18,880 --> 01:04:21,080 Speaker 2: helpful here and people get to have the joy of 1168 01:04:21,120 --> 01:04:23,440 Speaker 2: being curious and going down all the rabbit holes that 1169 01:04:23,480 --> 01:04:24,040 Speaker 2: we mentioned. 1170 01:04:24,360 --> 01:04:27,760 Speaker 1: Yeah, absolutely, thanks Matte, and so well, oh, what's the 1171 01:04:27,800 --> 01:04:32,160 Speaker 1: best people of saying people? It's joshuapiet dot com. 1172 01:04:32,360 --> 01:04:36,000 Speaker 2: W is my middle initial. There's a NASCAR driver and 1173 01:04:36,000 --> 01:04:38,360 Speaker 2: a Netflix director. There's people with the same name as me, 1174 01:04:38,760 --> 01:04:41,360 Speaker 2: and so I've had to insert that W. So Joshua 1175 01:04:41,520 --> 01:04:44,480 Speaker 2: wpat dot com. There's a contact form and if you 1176 01:04:44,640 --> 01:04:46,680 Speaker 2: just or you could look up UTS and my name 1177 01:04:46,760 --> 01:04:49,800 Speaker 2: and it will come up with contact details. So yeah, 1178 01:04:49,840 --> 01:04:51,880 Speaker 2: reach out. I'd love to hear from people, happy to 1179 01:04:52,120 --> 01:04:55,080 Speaker 2: kind of have more conversations and see where things had. 1180 01:04:55,240 --> 01:04:57,600 Speaker 1: Awesome, great stuff. Matt, thanks for your time. This has 1181 01:04:57,640 --> 01:05:03,720 Speaker 1: been bloody amazing.