WEBVTT - #2013 Transcranial Electrical Stimulation - David Gillespie

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<v Speaker 1>I get out your bloody champs. It's the project that's

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<v Speaker 1>You's Tiffany and Cook over there in her her rabbit

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<v Speaker 1>hole chewing on a fucking carrot. I'm not even being funny.

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<v Speaker 1>I'm not even being metaphoric. It's not an analogy. It's literal,

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<v Speaker 1>like having fucking bugs. Bunny on the podcast and when

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<v Speaker 1>I got on, she was just crunching and chomping. What

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<v Speaker 1>are you? Why are you eating a raw carrot?

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<v Speaker 2>Because I didn't want to feel like for the next

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<v Speaker 2>half an hour, I deep down I wanted to punch

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<v Speaker 2>you and David in the face, so I thought I'd

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<v Speaker 2>take the edge off with a carrot.

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<v Speaker 1>Why is the lady allowed to say that towards two men?

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<v Speaker 1>But if a man said that towards two women, I'd

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<v Speaker 1>be in trouble.

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<v Speaker 2>It's probably probably running out on it.

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<v Speaker 1>The gispo goialispaw was a joke. We know she, we

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<v Speaker 1>know God here, oh god. It was a rhetorical question.

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<v Speaker 3>Everyone.

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<v Speaker 1>I didn't really mean it. There's no there's nothing in it.

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<v Speaker 1>Don't send you an email. But Gilespo is going to

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<v Speaker 1>answer it anyway. Fuck, that's the problem you have him on.

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<v Speaker 1>You ask any question there's a fucking answer. Come on,

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<v Speaker 1>what is it?

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<v Speaker 3>Testosterone of course is the answer. Yeah, well, because because

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<v Speaker 3>the version of humans that has the testosterone supplement can

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<v Speaker 3>be quite dangerous, and so it has to have rules

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<v Speaker 3>around it.

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<v Speaker 1>I don't want to point out that there's a female

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<v Speaker 1>on the show that's probably got more testosterone than you, Gilespo.

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<v Speaker 3>So a, you know, are you whized honestly? Because yeah,

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<v Speaker 3>she's fit and works out on everything, But that doesn't

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<v Speaker 3>mean she's got more testosterone. No, that is well, well

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<v Speaker 3>not unless she's taking extra of course.

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<v Speaker 1>No, No, I don't think.

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<v Speaker 3>I don't think versions there. I don't know.

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<v Speaker 1>I don't think there's anything on board that's untoward. I

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<v Speaker 1>don't think. I don't think Wada are going to be

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<v Speaker 1>knocking on her bloody door anytime on a rabbit hole

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<v Speaker 1>anytime soon. You should ask Gillespo what is the what

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<v Speaker 1>is the underlying mechanism of your your hangariness, tiff, your

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<v Speaker 1>pensity to want to punch someone in the face when

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<v Speaker 1>you can't get a carrot or similar?

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<v Speaker 2>Yeah, David, why is hungry such a big emotion for me?

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<v Speaker 3>Huh, Well, it's probably to do with the whole reward

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<v Speaker 3>cycle thing, So it's you know, the purpose of our

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<v Speaker 3>dopamine system is to make as seek useful rewards, and

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<v Speaker 3>one of the most basic useful rewards is food. So

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<v Speaker 3>if you're genuinely hungry, then your dopamine system is firing

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<v Speaker 3>up to force you to get food and respond to

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<v Speaker 3>that hunger. So you are on edge. Dopamine Remember, its

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<v Speaker 3>function is to put you on edge, make you more focused,

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<v Speaker 3>make your muscles work better, make you more determined to

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<v Speaker 3>achieve the rewards. So that's probably what you're experiencing.

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<v Speaker 2>Wow, I am carrot in hand.

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<v Speaker 1>Well, a carrot in hand? Did the carrot help? I

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<v Speaker 1>feel like a carrot's not particularly helpful?

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<v Speaker 2>Look, and it did. But it's better than an apple.

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<v Speaker 2>If I eat an apple when I'm hungry, it makes

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<v Speaker 2>me makes you hungrier. Great, Yeah.

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<v Speaker 1>You know?

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<v Speaker 3>Or do you want to know why? Yes, So.

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<v Speaker 1>Get comfortable everyone, No.

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<v Speaker 3>This one's a quick one. So fructose, which is the

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<v Speaker 3>primary sugar in an apple, is it causes It fires

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<v Speaker 3>the hunger system, so it fires the appetite. Its function

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<v Speaker 3>is to make us want to eat more. So, from

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<v Speaker 3>an evolutionary perspective, if we've got something sweet, it was

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<v Speaker 3>usually the thing we shoved in our mouth first because

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<v Speaker 3>it's sweet. We like sweet things, and it actually makes

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<v Speaker 3>us hungrier and gets our appetite system going and ready

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<v Speaker 3>for real food. So that's why. And a lot of

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<v Speaker 3>people will tell you that, a lot of people will say,

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<v Speaker 3>if I'm hungry, the worst thing in the world I

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<v Speaker 3>can eat is an apple, because as soon as I do,

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<v Speaker 3>I'm even hungrier. Now, mind you, karras probably not a

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<v Speaker 3>great solution because it's got some fructose in it too,

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<v Speaker 3>but nowhere near the quantities of of something like an apple.

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<v Speaker 2>I normally eat my apples and pears with peanut butter,

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<v Speaker 2>with nut butter on them, and Harps teased me the

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<v Speaker 2>other day when I said that they are delicious.

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<v Speaker 3>My sister in law did that too, and I thought

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<v Speaker 3>she was totally insane because she take she'd slice a

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<v Speaker 3>bit of apple off and then put peanut butter on it,

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<v Speaker 3>and I thought she was insane till I tried it.

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<v Speaker 3>It was really nice, so good.

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<v Speaker 1>Well, I think what that does too, it because you're

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<v Speaker 1>putting the fat with the sugar at low is what

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<v Speaker 1>they call I don't know if they still use that term,

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<v Speaker 1>but glycemic load. So it doesn't create such an insulin response,

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<v Speaker 1>so you probably do you get hanged? Are you if

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<v Speaker 1>you have that and some nut butter, are you satisfied

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<v Speaker 1>after that or do you still want more?

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<v Speaker 3>Yeah?

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<v Speaker 2>No, that's why I have it.

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<v Speaker 3>And the fat. The fat is what what he needs.

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<v Speaker 1>Gillespo, you were telling us, I don't know if you

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<v Speaker 1>want to share this, but fuck it, I'm opening the door.

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<v Speaker 1>You were telling us before we press the record button

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<v Speaker 1>that it's very, very differ dificult for people who are

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<v Speaker 1>vegans and eat only kind of raw vegan diets, which

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<v Speaker 1>there are not a lot, but there are people that

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<v Speaker 1>it's almost impossible enough for them, impossible for them to

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<v Speaker 1>get enough calories eating that way to survive.

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<v Speaker 3>Based. Yeah, I'm a little reluctant to talk about this

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<v Speaker 3>too much because it's a vague memory of a study

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<v Speaker 3>I read as I was reading about something else, but

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<v Speaker 3>I'm pretty sure that's what it said, which is a

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<v Speaker 3>raw food diet cannot supply sufficient calories to keep an

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<v Speaker 3>adult human alive. So and the only sort of asterisk

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<v Speaker 3>on that is that unless you include a lot of

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<v Speaker 3>raw foods that have a lot of fat in them,

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<v Speaker 3>like avocados and in that particular study, I think they

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<v Speaker 3>observed that a large percentage, very large percentage of the

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<v Speaker 3>diet of those people who were doing this successfully or

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<v Speaker 3>at least managing to stay alive. I guess we're people

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<v Speaker 3>who were doing it with a large amount of avocado

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<v Speaker 3>in it.

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<v Speaker 2>I've got a question, when did David, When did humans

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<v Speaker 2>start cooking food cooking meat?

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<v Speaker 3>At the transition? Well, you know, I wasn't there, but

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<v Speaker 3>I was, Oh, Craig was, Yeah, I thought it might

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<v Speaker 3>have been, but I didn't want to say anything. At

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<v Speaker 3>the transition from the tree hanging version of us, well,

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<v Speaker 3>you know, it's wrong to say version of us because

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<v Speaker 3>we're a separate species. But in the evolutionary transition from

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<v Speaker 3>generally being in jungles and swinging around in trees into

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<v Speaker 3>the grassland version, where there were no trees and things

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<v Speaker 3>to do, where we had to do some outside the

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<v Speaker 3>body processing of our food supply. And so what we

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<v Speaker 3>found is that we could get by with a lot

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<v Speaker 3>less intestine if we process the food before we put

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<v Speaker 3>it in our mouths, which is what cooking is. So

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<v Speaker 3>that's breaking the food down using fire before we put

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<v Speaker 3>it into our body. So we need a lot less

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<v Speaker 3>intestine to do that, and what we save in intestine

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<v Speaker 3>we make up for in brains. So there's a strong

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<v Speaker 3>theory that the reason we were able to grow such

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<v Speaker 3>large brains and be what we are is because of fire.

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<v Speaker 3>Because we discovered that the fire was bloody handy in

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<v Speaker 3>predigesting food, and if we predigested it, we didn't need

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<v Speaker 3>anywhere near as much a testine and we could invest

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<v Speaker 3>those resources in growing brain instead of gut.

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<v Speaker 1>So the answer to your question tip is nine thirty eight.

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<v Speaker 3>The question when I don't know the exact time, but

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<v Speaker 3>sometime between the transition between chimpionzee like versions of us

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<v Speaker 3>and US versions of us.

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<v Speaker 1>Did you see that they just recently David pushed the

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<v Speaker 1>modern Homo sapient timeline back by two hundred thousand years

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<v Speaker 1>from three hundred thousand to half a million, Like, I

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<v Speaker 1>didn't see that, but yeah, what they call modern Homo sapiens.

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<v Speaker 3>Yeah, that was the big question is what we did

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<v Speaker 3>to all our cousins, because we weren't the only species

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<v Speaker 3>of human, not by a long shot. So Neanderthals were

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<v Speaker 3>a separate species, for example, but there were others. And

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<v Speaker 3>how you think it's robusters, that's me yep. So the

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<v Speaker 3>big question is what do we do to them? Because

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<v Speaker 3>we probably did something to them, so I.

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<v Speaker 1>Think we all know what we did to them. That's okay,

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<v Speaker 1>it's and we haven't stopped doing that to each other.

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<v Speaker 1>By the way, we're.

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<v Speaker 3>The only species of humans left, so there could have

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<v Speaker 3>been other species. Well, there were other species and they

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<v Speaker 3>didn't survive and we did, which makes a casta finger

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<v Speaker 3>suspicion in our direction.

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<v Speaker 1>I suspect that's an interesting question, though, Tiff. It is

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<v Speaker 1>it is? And how long I should know this? But

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<v Speaker 1>you'll definitely know because you're the smartest bloke on the show.

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<v Speaker 1>Agriculture What is that like ten thousand years old? About

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<v Speaker 1>ten thousand? Yeah, it's what allowed.

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<v Speaker 3>Us to live in groups larger than about one hundred

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<v Speaker 3>and fifty because suddenly we could not have to we

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<v Speaker 3>didn't have to move to the food. We kept the

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<v Speaker 3>food and we created it, and then we could have

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<v Speaker 3>large groups of humans around where we created the food.

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<v Speaker 3>So we noticed that the grasses and so on could

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<v Speaker 3>be you know, you can grow fields of the things

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<v Speaker 3>and take the grains from them and then feed large

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<v Speaker 3>amounts of people, so which necessitated us evolving the capacity

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<v Speaker 3>to work well with other strangers, which is we've talked

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<v Speaker 3>about many, many times on the show, which is how

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<v Speaker 3>we evolved empathy, and why we evolved empathy is we

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<v Speaker 3>have to be able to trust other humans.

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<v Speaker 1>Le'd be fascinating, all right, now, that's not what we're

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<v Speaker 1>talking about today. But beautiful, beautiful intro. We are going

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<v Speaker 1>to chat today. I don't even know why, but about

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<v Speaker 1>transcranial electrical stimulation. I have a really fundamental and I

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<v Speaker 1>say basic fundamental understanding of what that is and why

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<v Speaker 1>it's used. But why are we chatting about that? Why

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<v Speaker 1>are your interest in that?

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<v Speaker 3>Because the t GA in Australia has recently approved that.

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<v Speaker 3>I think I didn't get a chance to look up

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<v Speaker 3>this article before I came on here, but I think

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<v Speaker 3>this is the case in the last few weeks or

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<v Speaker 3>so for treatment of depression. And this is the so

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<v Speaker 3>just for people who are not quite sure what this is.

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<v Speaker 3>This is they look like a skull cap sort of

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<v Speaker 3>a thing. Put it on your head for about twenty

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<v Speaker 3>minutes a day, passes an electric current into various bits

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<v Speaker 3>of your brain. And this is not the kind you

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<v Speaker 3>know In one flock flew over the cokoo's nest where

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<v Speaker 3>you're getting a little bitt of me or anything. This

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<v Speaker 3>is very very mild electrical current, and if it's done right,

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<v Speaker 3>it has been shown to produce improvement in symptoms associated

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<v Speaker 3>with depression. And this is in double blind trials where

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<v Speaker 3>this is the kind of thing you can try pretty effectively,

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<v Speaker 3>which is that you can give someone a cap to

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<v Speaker 3>put on their head that makes it feel like they're

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<v Speaker 3>getting electrical stimulation, but they're not, and so they don't

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<v Speaker 3>know if they're getting it. You don't know if they're

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<v Speaker 3>getting it, the researchers don't know. It's all double blinded

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<v Speaker 3>and you can measure the utcomes and so there have

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<v Speaker 3>been studies done in this, quite recent studies in it

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<v Speaker 3>that have shown that it can improve symptoms associated with anxiety, depression,

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<v Speaker 3>and even addiction. So there's a recent study done on

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<v Speaker 3>marijuana addiction. Long term marijuana addiction, which is off marijuana

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<v Speaker 3>is often prescribed for pain relief, increasingly so, and the

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<v Speaker 3>hidden story there is that there's often a significant risk

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<v Speaker 3>of addiction and getting people off the marijuana addiction once

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<v Speaker 3>it started it can be very very difficult, and there

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<v Speaker 3>have been studies using this kind of technology to essentially

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<v Speaker 3>break the addiction, reduce the cravings, improve sleep, outcomes, improve anxiety,

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<v Speaker 3>are comes, improved withdrawal symptoms, all of those kinds of things.

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<v Speaker 3>So this is an interesting technology. The more interesting bit

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<v Speaker 3>from my perspective is why why does this work? What

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<v Speaker 3>is it doing in the brain that is causing this

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<v Speaker 3>to have this effect? Because it's an interesting effect. If

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<v Speaker 3>you look at the studies on this and say, Okay,

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<v Speaker 3>what are they saying are the outcomes from this? It

0:12:55.160 --> 0:12:58.440
<v Speaker 3>is very very similar to the kinds of outcomes that

0:12:58.480 --> 0:13:01.000
<v Speaker 3>we've talked about before, where I said what you need

0:13:01.040 --> 0:13:04.280
<v Speaker 3>to do is find something to increase your focus. So

0:13:04.480 --> 0:13:07.079
<v Speaker 3>if you are addicted to something, if you're suffering anxiety,

0:13:07.120 --> 0:13:10.880
<v Speaker 3>for suffering depression, you need to find something to increase

0:13:10.880 --> 0:13:13.199
<v Speaker 3>your focus. And so remember we've talked about you could do,

0:13:13.240 --> 0:13:16.200
<v Speaker 3>you know, take up playing a musical instrument, you know,

0:13:16.320 --> 0:13:18.760
<v Speaker 3>as something that gets you into that flow state where

0:13:18.800 --> 0:13:23.880
<v Speaker 3>you are increasing focus. And if I think mentioned you know,

0:13:23.920 --> 0:13:26.360
<v Speaker 3>one of the big ones that's historically been there is

0:13:26.800 --> 0:13:30.240
<v Speaker 3>meditation and those sorts of things which achieve the same

0:13:30.280 --> 0:13:32.240
<v Speaker 3>sort of thing which is putting you into a state

0:13:32.280 --> 0:13:36.080
<v Speaker 3>where you are entirely focused on just one thing. So

0:13:36.440 --> 0:13:39.240
<v Speaker 3>the outcomes from studies that show those sorts of things

0:13:39.280 --> 0:13:41.800
<v Speaker 3>are very, very similar to the artcomes that we're seeing

0:13:42.240 --> 0:13:45.840
<v Speaker 3>for these electrical stimulation studies. And so the big and

0:13:46.000 --> 0:13:48.600
<v Speaker 3>obvious question is how is it doing it? And the

0:13:48.679 --> 0:13:51.360
<v Speaker 3>answer is, according to a couple of recent papers on this,

0:13:51.960 --> 0:13:57.360
<v Speaker 3>is it's showing it's been shown to stimulate dopamine. So

0:13:58.679 --> 0:14:03.240
<v Speaker 3>this electrical stimulation is causing dopamine stimulation in the right

0:14:03.280 --> 0:14:06.280
<v Speaker 3>parts of the brain where it's applied in the right way,

0:14:06.880 --> 0:14:11.320
<v Speaker 3>it's causing dopamine stimulation. So it's an artificial way of

0:14:11.400 --> 0:14:14.800
<v Speaker 3>inducing focus. So yeah, we could do a little experiment

0:14:14.840 --> 0:14:19.720
<v Speaker 3>on Tiff, because you know she's when she's craving food

0:14:19.760 --> 0:14:23.840
<v Speaker 3>and it's making her angry. You could stimulate dopamine by

0:14:23.920 --> 0:14:26.160
<v Speaker 3>putting one of these things on her head and see

0:14:26.200 --> 0:14:29.280
<v Speaker 3>if the cravings go away, and according to the studies,

0:14:29.400 --> 0:14:33.880
<v Speaker 3>there's a good chance they would. So that's the kind

0:14:33.920 --> 0:14:36.280
<v Speaker 3>of thing we're talking about, which is an artificial stimulation

0:14:36.320 --> 0:14:39.840
<v Speaker 3>of dopamine, which is of course the way everyone is

0:14:39.880 --> 0:14:45.680
<v Speaker 3>treating ADHD now. So ADHD is artificial, is treated with

0:14:45.760 --> 0:14:48.600
<v Speaker 3>artificial stimulation dopamine using drugs, So we know how to

0:14:48.640 --> 0:14:53.600
<v Speaker 3>stimulate dopamine very very easily. You give people a stimulant drug,

0:14:53.960 --> 0:14:57.600
<v Speaker 3>you know, like ADHD medication or cocaine or any other stimulant.

0:14:58.200 --> 0:15:01.440
<v Speaker 3>Not sorry, not advocating giving cocaine into ADHD kids, but

0:15:01.560 --> 0:15:05.760
<v Speaker 3>I'm just saying that the mechanism is the same. And

0:15:06.760 --> 0:15:10.360
<v Speaker 3>so the interesting thing here is you're achieving that kind

0:15:10.440 --> 0:15:16.720
<v Speaker 3>of result, but not with a drug and also not

0:15:16.920 --> 0:15:20.720
<v Speaker 3>with any herbal gerbil you know, prayer mat or anything.

0:15:21.040 --> 0:15:26.160
<v Speaker 3>You're doing it with a piece of technology. Now the

0:15:26.240 --> 0:15:32.320
<v Speaker 3>interesting question there is is that better Is that a

0:15:32.320 --> 0:15:35.800
<v Speaker 3>better way to do this than using a drug or

0:15:35.880 --> 0:15:38.200
<v Speaker 3>using something else that stimulates over I mean, so people

0:15:38.400 --> 0:15:42.120
<v Speaker 3>have been able to self treat and self medicate all

0:15:42.160 --> 0:15:45.440
<v Speaker 3>of these symptoms themselves by giving themselves a stimulant like smoking.

0:15:45.760 --> 0:15:49.320
<v Speaker 3>So people you know they're suffering stress or suffering cravings,

0:15:49.320 --> 0:15:51.960
<v Speaker 3>that they know that smoking is a solution, or drinking

0:15:52.080 --> 0:15:55.360
<v Speaker 3>is a solution, or getting on insta is a solution,

0:15:56.120 --> 0:15:58.600
<v Speaker 3>or playing a video game is a solution, because all

0:15:58.640 --> 0:16:03.800
<v Speaker 3>of those things stimulate dopamine. Eating a carrot or eating

0:16:03.840 --> 0:16:08.320
<v Speaker 3>a carrot, desiring the carrot is what stimulates the dopamine.

0:16:08.320 --> 0:16:12.200
<v Speaker 3>The eating of it is the satisfaction of it. So

0:16:13.160 --> 0:16:17.160
<v Speaker 3>the interesting question there is, Okay, so we know we

0:16:17.200 --> 0:16:20.040
<v Speaker 3>can this is no miracle. We can stimulate dopamine any

0:16:20.120 --> 0:16:23.040
<v Speaker 3>number of ways. Why should this thing be regarded as

0:16:23.080 --> 0:16:27.680
<v Speaker 3>anything more special? Well, because the study seemed to be

0:16:27.720 --> 0:16:31.840
<v Speaker 3>suggesting this is all like the for what of a

0:16:31.840 --> 0:16:35.880
<v Speaker 3>better term natural stimulation of dopamine that you get from

0:16:35.960 --> 0:16:38.320
<v Speaker 3>finding something puts you in a state of flow. So

0:16:38.360 --> 0:16:41.200
<v Speaker 3>it's not high enough and harsh enough to become addictive

0:16:41.360 --> 0:16:44.280
<v Speaker 3>in its own right. You're not going to become addicted

0:16:44.800 --> 0:16:48.680
<v Speaker 3>to putting the cap on twenty minutes to day. You are,

0:16:48.800 --> 0:16:53.720
<v Speaker 3>in essence using it as methadine, a methadone for other addictions,

0:16:53.760 --> 0:16:56.760
<v Speaker 3>which is is giving you enough of a dopamine hit

0:16:57.560 --> 0:17:01.080
<v Speaker 3>to satisfy the cravings and ap to you going after

0:17:01.120 --> 0:17:06.760
<v Speaker 3>the other addiction and start to address the symptoms like

0:17:06.800 --> 0:17:10.359
<v Speaker 3>depression and sleep interruption and anxiety and so on. But

0:17:11.359 --> 0:17:14.800
<v Speaker 3>it isn't strong enough that they're finding people are becoming

0:17:14.840 --> 0:17:17.320
<v Speaker 3>addicted to this simulation.

0:17:18.400 --> 0:17:20.280
<v Speaker 1>Now you're making me want to go and buy one.

0:17:20.359 --> 0:17:21.880
<v Speaker 1>I'm just having a little bit of a look here

0:17:21.920 --> 0:17:24.960
<v Speaker 1>on I wonder if you can find me one of

0:17:25.000 --> 0:17:29.640
<v Speaker 1>those on craigslist. Iff uses and research. This is AI, everybody,

0:17:29.640 --> 0:17:33.160
<v Speaker 1>so take it with a grain of salt. Cognitive enhancement, memory, learning,

0:17:33.240 --> 0:17:39.480
<v Speaker 1>problem solving, improved mental health being studied for depression, addiction, anxiety.

0:17:39.520 --> 0:17:43.439
<v Speaker 1>As David was talking about rehab, stroke, recovery, motor learning,

0:17:43.520 --> 0:17:47.160
<v Speaker 1>pain and fatigue, some trials in chronic pain and fatigue syndromes.

0:17:47.760 --> 0:17:51.440
<v Speaker 1>That's interesting and in terms of safety, generally considered safe

0:17:51.440 --> 0:17:56.320
<v Speaker 1>when done properly. Mild tingling, itching or readiness, blah blah blah, rare,

0:17:56.520 --> 0:18:01.120
<v Speaker 1>rare symptoms, headache, dizziness, long term effects still being studied.

0:18:01.160 --> 0:18:04.040
<v Speaker 1>But it seems to I mean, we're not again everyone,

0:18:04.320 --> 0:18:07.040
<v Speaker 1>as David always says, we're not advising or recommending, We're

0:18:07.080 --> 0:18:11.560
<v Speaker 1>just having a chat about it. But yeah, I wonder like,

0:18:11.760 --> 0:18:14.720
<v Speaker 1>is it something that needs to be your understanding anyway, David,

0:18:14.800 --> 0:18:17.280
<v Speaker 1>that it needs to be used consistently or use it

0:18:17.320 --> 0:18:19.000
<v Speaker 1>for a period of time and then put it back

0:18:19.040 --> 0:18:19.600
<v Speaker 1>in the cupboard.

0:18:20.800 --> 0:18:23.120
<v Speaker 3>Well, I guess it depends how your mileage may vary.

0:18:23.520 --> 0:18:25.240
<v Speaker 3>By the way, while you were blathering on there, I

0:18:25.280 --> 0:18:27.320
<v Speaker 3>did check the TGA.

0:18:28.080 --> 0:18:32.959
<v Speaker 1>Hey, why when I'm sharing, am I blathering.

0:18:32.480 --> 0:18:35.040
<v Speaker 3>On because you were just reading an AI answer.

0:18:35.720 --> 0:18:37.080
<v Speaker 1>I was sharing some.

0:18:42.040 --> 0:18:44.800
<v Speaker 3>Anyway while you were reading that AI answer.

0:18:44.480 --> 0:18:46.399
<v Speaker 1>Back in therapy. You know what I'm going to need.

0:18:46.600 --> 0:18:49.760
<v Speaker 1>I'm going to need some transcrani electrical stimulation from a

0:18:49.800 --> 0:18:53.520
<v Speaker 1>depression from hanging out with that bastard every two weeks.

0:18:54.920 --> 0:18:59.560
<v Speaker 3>Possibly, yeah, anyway, Yes, the TGA did to prove it

0:19:00.280 --> 0:19:05.040
<v Speaker 3>last two weeks ago. So Australian Therapeutic Goods Administration has

0:19:05.080 --> 0:19:08.800
<v Speaker 3>approved for conditions like depression and chronic pain.

0:19:09.480 --> 0:19:14.359
<v Speaker 1>And so would who would prescribe that? Like, not like

0:19:14.400 --> 0:19:20.439
<v Speaker 1>a psychiatrist, a GP, who like, if somebody's got issues,

0:19:20.440 --> 0:19:23.520
<v Speaker 1>who's going to make that decision or prescribe or recommend that?

0:19:23.800 --> 0:19:26.159
<v Speaker 3>Well, I suspect the first off, as with anything medical,

0:19:26.160 --> 0:19:29.840
<v Speaker 3>would would be your GP. So they're your primary health

0:19:29.840 --> 0:19:33.919
<v Speaker 3>care provider, so you know, and i'd recommend anyone listening

0:19:33.920 --> 0:19:35.680
<v Speaker 3>to this who's thinking, Oh, I wouldn't mind giving that

0:19:35.720 --> 0:19:39.400
<v Speaker 3>a try first first porter call, talk to your GP

0:19:39.600 --> 0:19:43.720
<v Speaker 3>about it, you know, don't I don't know how easy

0:19:43.720 --> 0:19:47.679
<v Speaker 3>these things are to buy, you know, or even how

0:19:47.720 --> 0:19:50.159
<v Speaker 3>you get access to them, but they are approved for

0:19:50.240 --> 0:19:54.400
<v Speaker 3>certain uses in Australia and that's interesting because it's new,

0:19:54.920 --> 0:19:58.320
<v Speaker 3>and more interesting to me because it's a completely different

0:19:58.320 --> 0:20:01.160
<v Speaker 3>way of approaching this. The only other time I've seen

0:20:01.840 --> 0:20:06.399
<v Speaker 3>technology used as a cure for depression or anxiety is

0:20:06.440 --> 0:20:08.920
<v Speaker 3>a group in the United States that came out last

0:20:08.960 --> 0:20:12.000
<v Speaker 3>year and they got the equivalent of TGA approved approval

0:20:12.040 --> 0:20:15.199
<v Speaker 3>in the United States on what it was, essentially a

0:20:15.280 --> 0:20:19.960
<v Speaker 3>video game. And I think we may have even talked

0:20:19.960 --> 0:20:20.400
<v Speaker 3>about it.

0:20:21.240 --> 0:20:23.679
<v Speaker 1>I vaguely remember a brief chat about that.

0:20:23.760 --> 0:20:29.000
<v Speaker 3>Yeah, yeah, and and my point at the time was, well,

0:20:29.040 --> 0:20:33.400
<v Speaker 3>of course video games stimulate overman, so you would imagine

0:20:33.400 --> 0:20:36.600
<v Speaker 3>that that would work. This first time anyone had ever

0:20:36.960 --> 0:20:39.760
<v Speaker 3>gotten therapeutic approval for the use of a video game.

0:20:40.160 --> 0:20:44.080
<v Speaker 3>The problem with a video game as a solution here

0:20:44.400 --> 0:20:47.840
<v Speaker 3>is that it's like saying, my solution to my cocaine

0:20:47.880 --> 0:20:53.840
<v Speaker 3>addiction is more cocaine. And the problem, by the way,

0:20:53.920 --> 0:20:56.240
<v Speaker 3>it's an ad running around at the moment where they

0:20:56.240 --> 0:21:01.679
<v Speaker 3>say guys suffering from nicotine cravings and they call it

0:21:01.720 --> 0:21:03.600
<v Speaker 3>that on the ad. I can't remember this, so I

0:21:03.600 --> 0:21:09.280
<v Speaker 3>think the ads for nicorettes suffering for nicotine craving and

0:21:09.320 --> 0:21:12.280
<v Speaker 3>they say the solution is nicotine.

0:21:13.720 --> 0:21:16.520
<v Speaker 1>I know what that's dawn on me. I'm like, he's

0:21:16.560 --> 0:21:19.399
<v Speaker 1>got yeah, so let's give him nicotine to stop the

0:21:19.480 --> 0:21:20.240
<v Speaker 1>nicotine crave.

0:21:20.359 --> 0:21:22.480
<v Speaker 3>That's right. Do want to add for someone who's adicted to

0:21:22.520 --> 0:21:24.800
<v Speaker 3>cocaine and say, well, the solution is you need some

0:21:24.840 --> 0:21:27.840
<v Speaker 3>more cocaine. So guess what, we've got some for you.

0:21:28.280 --> 0:21:31.560
<v Speaker 1>We've got cocaine chewing gum or cocaine patches for you.

0:21:32.520 --> 0:21:36.200
<v Speaker 3>Yeah. So, And that's the problem is, that's why these

0:21:36.200 --> 0:21:38.359
<v Speaker 3>things are not solutions. It's why drinking is not a

0:21:38.400 --> 0:21:41.680
<v Speaker 3>solution to alcoholism, even though it does make you feel

0:21:41.720 --> 0:21:46.280
<v Speaker 3>better immediately and does remove most of the symptoms because

0:21:46.320 --> 0:21:51.320
<v Speaker 3>you are stimulating dopamine, which will help the problem is

0:21:51.359 --> 0:21:53.919
<v Speaker 3>that usually you're stimulating it too high. You raise the

0:21:53.960 --> 0:21:57.640
<v Speaker 3>delta foss B threshold. Remember that's the resistance they've offered dopamine,

0:21:57.720 --> 0:21:59.560
<v Speaker 3>and every time you raise it, you make it harder

0:21:59.600 --> 0:22:03.080
<v Speaker 3>to break it next time. The interesting thing about this

0:22:03.240 --> 0:22:05.679
<v Speaker 3>is this seems like it might be soft enough and

0:22:05.720 --> 0:22:08.960
<v Speaker 3>slow enough that it isn't quite reaching enough of a

0:22:08.960 --> 0:22:13.440
<v Speaker 3>threshold to do that, and we used over time may

0:22:13.560 --> 0:22:16.199
<v Speaker 3>well reduce those symptoms and bring you back down to

0:22:16.240 --> 0:22:18.320
<v Speaker 3>a more normal level, which is after all what I

0:22:18.359 --> 0:22:22.240
<v Speaker 3>advocate people do without drugs anyway, which is find that

0:22:22.280 --> 0:22:25.199
<v Speaker 3>flow state, find that focus state that allows you to

0:22:25.200 --> 0:22:27.280
<v Speaker 3>do it. And I guess this is the ozempic of

0:22:27.400 --> 0:22:29.880
<v Speaker 3>mental health here in that if you can't be bothered

0:22:29.920 --> 0:22:34.000
<v Speaker 3>doing that, then maybe there's a shortcut here if you.

0:22:34.080 --> 0:22:37.000
<v Speaker 1>Had your hand up three minutes ago and David just plow.

0:22:37.680 --> 0:22:40.239
<v Speaker 3>Just ignore it. You know why, Tiff, because I have

0:22:40.520 --> 0:22:42.719
<v Speaker 3>on my screen Craig has made it. I'm sure this

0:22:42.760 --> 0:22:45.800
<v Speaker 3>is something he's done. It's made, He's made him the

0:22:45.880 --> 0:22:50.040
<v Speaker 3>feature thing in the So you're just a little icon

0:22:50.160 --> 0:22:51.720
<v Speaker 3>up in the corner for me, How on.

0:22:51.680 --> 0:22:55.480
<v Speaker 1>Earth am I blamed for what's going on on your

0:22:55.520 --> 0:22:56.479
<v Speaker 1>computering points?

0:22:56.520 --> 0:22:56.720
<v Speaker 2>Land?

0:22:57.520 --> 0:22:58.840
<v Speaker 1>If what's your question for.

0:22:59.520 --> 0:23:05.480
<v Speaker 4>I would interested how what's his name? How closely related

0:23:05.640 --> 0:23:11.080
<v Speaker 4>or not? This process is to electric electroconvulsive therapy.

0:23:11.600 --> 0:23:15.080
<v Speaker 3>Not really, not really, not not really. So this is

0:23:15.280 --> 0:23:19.879
<v Speaker 3>very low voltages and applied to very specific parts of

0:23:19.880 --> 0:23:22.240
<v Speaker 3>the brain that are known to be receptive to this.

0:23:22.440 --> 0:23:25.879
<v Speaker 3>So you can't just get out some batteries and you know,

0:23:26.359 --> 0:23:33.359
<v Speaker 3>wire them up to your brain. Craig was going to

0:23:33.400 --> 0:23:35.240
<v Speaker 3>hook himself up to a car battery.

0:23:36.880 --> 0:23:41.440
<v Speaker 1>I need some bloody cranial stimulation, some cognitive enhancement.

0:23:42.320 --> 0:23:45.639
<v Speaker 3>So this is this is quite when you look at

0:23:45.640 --> 0:23:48.399
<v Speaker 3>the studies on this and look at the various I mean,

0:23:48.400 --> 0:23:51.480
<v Speaker 3>there's several different types of it, but look at the

0:23:51.520 --> 0:23:53.480
<v Speaker 3>way they've been studying and the type they've used and

0:23:53.480 --> 0:23:57.720
<v Speaker 3>how they've used it. It's really very precise stuff. So

0:23:58.080 --> 0:24:01.359
<v Speaker 3>it's and it's very low voltage. So this is this

0:24:01.440 --> 0:24:04.560
<v Speaker 3>is intended to be. And that's why in that AI

0:24:04.640 --> 0:24:07.720
<v Speaker 3>you were reading out before, Craig, they were saying, you know,

0:24:07.800 --> 0:24:11.000
<v Speaker 3>in terms of harm, there's no real evidence of harm

0:24:11.040 --> 0:24:11.320
<v Speaker 3>from this.

0:24:12.480 --> 0:24:15.240
<v Speaker 1>Now now he's listening to the AI. A minute ago

0:24:15.280 --> 0:24:18.560
<v Speaker 1>it was bullshit, and now he's fucking referencing it. I

0:24:18.760 --> 0:24:21.639
<v Speaker 1>tell you what. But I wonder, David, now that this

0:24:21.720 --> 0:24:24.639
<v Speaker 1>has been approved, I wonder what practically that means. I

0:24:24.680 --> 0:24:27.560
<v Speaker 1>wonder if that's going to be I wonder if we'll

0:24:27.560 --> 0:24:31.359
<v Speaker 1>see that being used, you know, more and more to

0:24:31.880 --> 0:24:33.280
<v Speaker 1>treat people with these issues.

0:24:33.880 --> 0:24:36.639
<v Speaker 3>The interesting bit, and this is the bit I'm really

0:24:36.640 --> 0:24:40.000
<v Speaker 3>interested in, and I've seen some preliminary work in this

0:24:40.240 --> 0:24:42.359
<v Speaker 3>is the idea that perhaps this could be used for

0:24:42.440 --> 0:24:47.439
<v Speaker 3>treatment of ADHD, which remember from our discussions, you know,

0:24:47.880 --> 0:24:50.240
<v Speaker 3>along the way here, ADHD is the sort of the

0:24:50.280 --> 0:24:54.800
<v Speaker 3>first stop on the highway to anxiety and depression as

0:24:54.840 --> 0:24:57.520
<v Speaker 3>a result of your dopemine levels being too low because

0:24:57.520 --> 0:25:03.760
<v Speaker 3>of addiction and stress. And this should be a reasonable

0:25:04.080 --> 0:25:07.680
<v Speaker 3>solution to that, certainly a more reasonable solution than the

0:25:07.760 --> 0:25:12.840
<v Speaker 3>giving kids drugs. If it works. I think it probably should,

0:25:13.720 --> 0:25:17.280
<v Speaker 3>just theoretically, and so other people are certainly thinking along

0:25:17.320 --> 0:25:20.679
<v Speaker 3>those lines as well, because there are trials underway in

0:25:20.720 --> 0:25:21.320
<v Speaker 3>that respect.

0:25:23.080 --> 0:25:27.160
<v Speaker 1>Well, I will be interested to see what happens. Tip

0:25:27.160 --> 0:25:27.880
<v Speaker 1>would you do it?

0:25:27.960 --> 0:25:30.920
<v Speaker 2>If you google it as we speak? Now? How much?

0:25:30.960 --> 0:25:35.320
<v Speaker 1>If you can get a home? See if you can

0:25:35.359 --> 0:25:39.000
<v Speaker 1>get a home kid, jump start your brain off your motorbike.

0:25:41.720 --> 0:25:42.400
<v Speaker 1>I'll tell you what.

0:25:42.640 --> 0:25:43.359
<v Speaker 2>For it now.

0:25:44.040 --> 0:25:47.320
<v Speaker 1>Well that's interesting, Well, mate, I think we're done. There

0:25:47.480 --> 0:25:50.280
<v Speaker 1>was anything else, anything else going on before you go

0:25:50.400 --> 0:25:53.239
<v Speaker 1>anything on planet Gillespie. That's bloody going off like a

0:25:53.240 --> 0:25:54.040
<v Speaker 1>frog in a sock.

0:25:54.160 --> 0:25:57.960
<v Speaker 3>Do we look there? I'm setting up in websit here.

0:25:58.000 --> 0:25:59.720
<v Speaker 3>This is it? You know how you're always tell me

0:25:59.720 --> 0:26:01.720
<v Speaker 3>how I wish at marketing and you're right.

0:26:02.560 --> 0:26:04.040
<v Speaker 1>Well, yeah you are.

0:26:05.560 --> 0:26:08.639
<v Speaker 3>Well I've sorted that. Well, I'm on the way to

0:26:08.760 --> 0:26:11.960
<v Speaker 3>sorting that out and so from now on, all people

0:26:12.000 --> 0:26:13.720
<v Speaker 3>have to remember is my name. So you just go

0:26:13.800 --> 0:26:16.480
<v Speaker 3>to David Gillespie dot org and you'll see links to

0:26:16.520 --> 0:26:19.159
<v Speaker 3>all the articles that we talk about, and as a

0:26:19.200 --> 0:26:22.160
<v Speaker 3>special feature, I'm even going to put links to these

0:26:22.280 --> 0:26:23.720
<v Speaker 3>chats on that website.

0:26:24.040 --> 0:26:28.320
<v Speaker 1>Shit, well, it's about time you dragged yourself out of

0:26:28.320 --> 0:26:31.720
<v Speaker 1>the bloody nineteen seventies and got yourself, you know, an

0:26:31.760 --> 0:26:37.200
<v Speaker 1>electronic brochure, a front of housefo you dot org tip?

0:26:37.280 --> 0:26:39.520
<v Speaker 1>What have you discovered? Have you got a home kid yet?

0:26:41.000 --> 0:26:43.720
<v Speaker 2>Cool? Eighteen hundred and I'll have one in the mail.

0:26:45.520 --> 0:26:47.480
<v Speaker 1>What is it? Read out? What you're looking at?

0:26:48.320 --> 0:26:52.120
<v Speaker 2>Well, now I'm asking chatters about it because I like chatters.

0:26:51.119 --> 0:26:54.440
<v Speaker 1>To tell me, oh no, don't ask chatters. All right,

0:26:54.520 --> 0:26:58.080
<v Speaker 1>that'll do, Doctor Gillespie. We appreciate. We'll say goodbye affair,

0:26:58.160 --> 0:27:01.439
<v Speaker 1>but mate, thanks for the chat. Always always good to

0:27:01.440 --> 0:27:01.920
<v Speaker 1>catch up.

0:27:02.600 --> 0:27:03.120
<v Speaker 3>Good to chat